Compile Data Set for Download or QSAR

Found 11 hits of ic50 for UniProtKB: P16435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM50236853 (CHEMBL4094677) Show SMILES Cc1coc-2c1C(=O)C(=O)c1ccc(C)cc-21 Show InChI InChI=1S/C14H10O3/c1-7-3-4-9-10(5-7)14-11(8(2)6-17-14)13(16)12(9)15/h3-6H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM50236859 (CHEMBL4086536) Show SMILES Cc1cc2-c3occc3C(=O)C(=O)c2cc1C Show InChI InChI=1S/C14H10O3/c1-7-5-10-11(6-8(7)2)14-9(3-4-17-14)12(15)13(10)16/h3-6H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM81348 (β-Lapachone (A3) | Beta lapachone | R115 (Rea...) Show SMILES CC1(C)CCC2=C(O1)c1ccccc1C(=O)C2=O |c:5| Show InChI InChI=1S/C15H14O3/c1-15(2)8-7-11-13(17)12(16)9-5-3-4-6-10(9)14(11)18-15/h3-6H,7-8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM50236854 (CHEMBL4074173) Show SMILES Cc1coc-2c1C(=O)C(=O)c1c(C)ccc(C)c-21 Show InChI InChI=1S/C15H12O3/c1-7-4-5-8(2)11-10(7)13(16)14(17)12-9(3)6-18-15(11)12/h4-6H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM50236863 (CHEMBL3398294) Show SMILES COc1cccc2C(=O)C(=O)C3=C(OC(C)C3(C)C)c12 |t:11| Show InChI InChI=1S/C16H16O4/c1-8-16(2,3)12-14(18)13(17)9-6-5-7-10(19-4)11(9)15(12)20-8/h5-8H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM50236858 (CHEMBL4098063) Show SMILES CCc1coc-2c1C(=O)C(=O)c1cc(C)c(C)cc-21 Show InChI InChI=1S/C16H14O3/c1-4-10-7-19-16-12-6-9(3)8(2)5-11(12)14(17)15(18)13(10)16/h5-7H,4H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1a				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM50236857 (CHEMBL4080037) Show SMILES Cc1coc-2c1C(=O)C(=O)c1cc(C)ccc-21 Show InChI InChI=1S/C14H10O3/c1-7-3-4-9-10(5-7)12(15)13(16)11-8(2)6-17-14(9)11/h3-6H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM50236860 (CHEMBL4065098) Show SMILES CCc1coc-2c1C(=O)C(=O)c1cc(C)ccc-21 Show InChI InChI=1S/C15H12O3/c1-3-9-7-18-15-10-5-4-8(2)6-11(10)13(16)14(17)12(9)15/h4-7H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1a				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM50236861 (CHEMBL3398292) Show SMILES COc1ccc2C3=C(C(=O)C(=O)c2c1)C(C)(C)C(C)O3 |c:6| Show InChI InChI=1S/C16H16O4/c1-8-16(2,3)12-14(18)13(17)11-7-9(19-4)5-6-10(11)15(12)20-8/h5-8H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM50236862 (CHEMBL3398293) Show SMILES COc1ccc2C(=O)C(=O)C3=C(OC(C)C3(C)C)c2c1 |t:10| Show InChI InChI=1S/C16H16O4/c1-8-16(2,3)12-14(18)13(17)10-6-5-9(19-4)7-11(10)15(12)20-8/h5-8H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair
NADPH--cytochrome P450 reductase (Homo sapiens (Human))	BDBM50236855 (CHEMBL4102425) Show SMILES Cc1coc-2c1C(=O)C(=O)c1cc(C)c(C)cc-21 Show InChI InChI=1S/C15H12O3/c1-7-4-10-11(5-8(7)2)15-12(9(3)6-18-15)14(17)13(10)16/h4-6H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2; Maximum inhibition reached only 50%				Eur J Med Chem 129: 27-40 (2017) Article DOI: 10.1016/j.ejmech.2017.02.004 BindingDB Entry DOI: 10.7270/Q24170BB
					More data for this Ligand-Target Pair