Compile Data Set for Download or QSAR

Found 250 hits of ic50 data for polymerid = 1622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533354 (CHEMBL4455962) Show SMILES On1c(=O)cc(Nc2ccc(cc2)-c2ccc(Cl)cc2)[nH]c1=O Show InChI InChI=1S/C16H12ClN3O3/c17-12-5-1-10(2-6-12)11-3-7-13(8-4-11)18-14-9-15(21)20(23)16(22)19-14/h1-9,18,23H,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533372 (CHEMBL4454510) Show SMILES COc1cccc(OC)c1-c1cccc(Nc2cc(=O)n(O)c(=O)[nH]2)c1 Show InChI InChI=1S/C18H17N3O5/c1-25-13-7-4-8-14(26-2)17(13)11-5-3-6-12(9-11)19-15-10-16(22)21(24)18(23)20-15/h3-10,19,24H,1-2H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533353 (CHEMBL4549947) Show SMILES Cc1ccc(cc1)-c1ccc(Nc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C17H15N3O3/c1-11-2-4-12(5-3-11)13-6-8-14(9-7-13)18-15-10-16(21)20(23)17(22)19-15/h2-10,18,23H,1H3,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50468800 (CHEMBL4288759) Show SMILES On1c2ncccc2c(Nc2ccc(cc2)-c2cnc3ccccc3c2)nc1=O Show InChI InChI=1S/C22H15N5O2/c28-22-26-20(18-5-3-11-23-21(18)27(22)29)25-17-9-7-14(8-10-17)16-12-15-4-1-2-6-19(15)24-13-16/h1-13,29H,(H,25,26,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533398 (CHEMBL4438951) Show SMILES Cn1c(Nc2cccc(c2)-c2ccc(cc2)C#N)cc(=O)n(O)c1=O Show InChI InChI=1S/C18H14N4O3/c1-21-16(10-17(23)22(25)18(21)24)20-15-4-2-3-14(9-15)13-7-5-12(11-19)6-8-13/h2-10,20,25H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533383 (CHEMBL4471917) Show SMILES Cn1c(Nc2cccc(c2)-c2ccc(O)cc2)cc(=O)n(O)c1=O Show InChI InChI=1S/C17H15N3O4/c1-19-15(10-16(22)20(24)17(19)23)18-13-4-2-3-12(9-13)11-5-7-14(21)8-6-11/h2-10,18,21,24H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533399 (CHEMBL4586421) Show SMILES COc1ccc(cc1)-c1ccc(Nc2cc(=O)n(O)c(=O)n2C)cc1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-14-7-3-12(4-8-14)13-5-9-15(25-2)10-6-13/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50533367 (CHEMBL4461191) Show SMILES Oc1cccc(c1)-c1ccc(Nc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H13N3O4/c20-13-3-1-2-11(8-13)10-4-6-12(7-5-10)17-14-9-15(21)19(23)16(22)18-14/h1-9,17,20,23H,(H,18,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533358 (CHEMBL4466948) Show SMILES Cn1c(Nc2ccc(cc2)-c2ccccc2)cc(=O)n(O)c1=O Show InChI InChI=1S/C17H15N3O3/c1-19-15(11-16(21)20(23)17(19)22)18-14-9-7-13(8-10-14)12-5-3-2-4-6-12/h2-11,18,23H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533355 (CHEMBL4437367) Show SMILES COc1cccc(c1)-c1ccc(Nc2cc(=O)n(O)c(=O)n2C)cc1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-14-8-6-12(7-9-14)13-4-3-5-15(10-13)25-2/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50533405 (CHEMBL4550191) Show SMILES Oc1ccc(cc1)-c1ccc(Nc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H13N3O4/c20-13-7-3-11(4-8-13)10-1-5-12(6-2-10)17-14-9-15(21)19(23)16(22)18-14/h1-9,17,20,23H,(H,18,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50533386 (CHEMBL4466368) Show SMILES Oc1ccccc1-c1ccc(Nc2cc(=O)n(O)c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H13N3O4/c20-13-4-2-1-3-12(13)10-5-7-11(8-6-10)17-14-9-15(21)19(23)16(22)18-14/h1-9,17,20,23H,(H,18,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50468800 (CHEMBL4288759) Show SMILES On1c2ncccc2c(Nc2ccc(cc2)-c2cnc3ccccc3c2)nc1=O Show InChI InChI=1S/C22H15N5O2/c28-22-26-20(18-5-3-11-23-21(18)27(22)29)25-17-9-7-14(8-10-17)16-12-15-4-1-2-6-19(15)24-13-16/h1-13,29H,(H,25,26,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533402 (CHEMBL4581611) Show SMILES Cn1c(Nc2cccc(c2)-c2ccccc2)cc(=O)n(O)c1=O Show InChI InChI=1S/C17H15N3O3/c1-19-15(11-16(21)20(23)17(19)22)18-14-9-5-8-13(10-14)12-6-3-2-4-7-12/h2-11,18,23H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50468846 (CHEMBL4291913) Show SMILES On1c(=O)cc(Nc2cccc(c2)-c2ccc(Cl)cc2)[nH]c1=O Show InChI InChI=1S/C16H12ClN3O3/c17-12-6-4-10(5-7-12)11-2-1-3-13(8-11)18-14-9-15(21)20(23)16(22)19-14/h1-9,18,23H,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533404 (CHEMBL4445796) Show SMILES Cn1c(Nc2cccc(c2)-c2cncnc2)cc(=O)n(O)c1=O Show InChI InChI=1S/C15H13N5O3/c1-19-13(6-14(21)20(23)15(19)22)18-12-4-2-3-10(5-12)11-7-16-9-17-8-11/h2-9,18,23H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533378 (CHEMBL4440667) Show SMILES Cn1c(Nc2ccc(cc2)-c2cccc(c2)C#N)cc(=O)n(O)c1=O Show InChI InChI=1S/C18H14N4O3/c1-21-16(10-17(23)22(25)18(21)24)20-15-7-5-13(6-8-15)14-4-2-3-12(9-14)11-19/h2-10,20,25H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533412 (CHEMBL4472002) Show SMILES Cn1c(Oc2cccc(c2)-c2cccc(O)c2)cc(=O)n(O)c1=O Show InChI InChI=1S/C17H14N2O5/c1-18-16(10-15(21)19(23)17(18)22)24-14-7-3-5-12(9-14)11-4-2-6-13(20)8-11/h2-10,20,23H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533357 (CHEMBL4553834) Show SMILES Cn1c(Oc2cccc(c2)-c2cccc(c2)C#N)cc(=O)n(O)c1=O Show InChI InChI=1S/C18H13N3O4/c1-20-17(10-16(22)21(24)18(20)23)25-15-7-3-6-14(9-15)13-5-2-4-12(8-13)11-19/h2-10,24H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533403 (CHEMBL4563882) Show SMILES COc1ccc(cc1OC)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C19H19N3O5/c1-21-17(11-18(23)22(25)19(21)24)20-14-6-4-5-12(9-14)13-7-8-15(26-2)16(10-13)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533399 (CHEMBL4586421) Show SMILES COc1ccc(cc1)-c1ccc(Nc2cc(=O)n(O)c(=O)n2C)cc1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-14-7-3-12(4-8-14)13-5-9-15(25-2)10-6-13/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50533354 (CHEMBL4455962) Show SMILES On1c(=O)cc(Nc2ccc(cc2)-c2ccc(Cl)cc2)[nH]c1=O Show InChI InChI=1S/C16H12ClN3O3/c17-12-5-1-10(2-6-12)11-3-7-13(8-4-11)18-14-9-15(21)20(23)16(22)19-14/h1-9,18,23H,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533374 (CHEMBL4441277) Show SMILES COc1cccc(c1)-c1cccc(Oc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C18H16N2O5/c1-19-17(11-16(21)20(23)18(19)22)25-15-8-4-6-13(10-15)12-5-3-7-14(9-12)24-2/h3-11,23H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50533384 (CHEMBL4545702) Show SMILES COc1ccc(cc1)-c1ccccc1Oc1cc(=O)n(O)c(=O)n1C Show InChI InChI=1S/C18H16N2O5/c1-19-17(11-16(21)20(23)18(19)22)25-15-6-4-3-5-14(15)12-7-9-13(24-2)10-8-12/h3-11,23H,1-2H3	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV integrase pre-incubated for 10 mins before addition of oligo-5'-biotin ATGTGGAAAATCTCTAGCA annealed with ACTGCTAGAGATTTTCCACAT 3'-C...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533379 (CHEMBL4463922) Show SMILES COc1ccccc1-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-13-7-5-6-12(10-13)14-8-3-4-9-15(14)25-2/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533375 (CHEMBL4514889) Show SMILES COc1ccc(c(OC)c1)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C19H19N3O5/c1-21-17(11-18(23)22(25)19(21)24)20-13-6-4-5-12(9-13)15-8-7-14(26-2)10-16(15)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533369 (CHEMBL4473298) Show SMILES Cn1c(Nc2cccc(c2)-c2cccc(c2)C#N)cc(=O)n(O)c1=O Show InChI InChI=1S/C18H14N4O3/c1-21-16(10-17(23)22(25)18(21)24)20-15-7-3-6-14(9-15)13-5-2-4-12(8-13)11-19/h2-10,20,25H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533360 (CHEMBL4438393) Show SMILES Cn1c(Nc2ccc(cc2)-c2ccc(cc2)C#N)cc(=O)n(O)c1=O Show InChI InChI=1S/C18H14N4O3/c1-21-16(10-17(23)22(25)18(21)24)20-15-8-6-14(7-9-15)13-4-2-12(11-19)3-5-13/h2-10,20,25H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533363 (CHEMBL4440786) Show SMILES Cn1c(Oc2cccc(c2)-c2ccccc2)cc(=O)n(O)c1=O Show InChI InChI=1S/C17H14N2O4/c1-18-16(11-15(20)19(22)17(18)21)23-14-9-5-8-13(10-14)12-6-3-2-4-7-12/h2-11,22H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533398 (CHEMBL4438951) Show SMILES Cn1c(Nc2cccc(c2)-c2ccc(cc2)C#N)cc(=O)n(O)c1=O Show InChI InChI=1S/C18H14N4O3/c1-21-16(10-17(23)22(25)18(21)24)20-15-4-2-3-14(9-15)13-7-5-12(11-19)6-8-13/h2-10,20,25H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533369 (CHEMBL4473298) Show SMILES Cn1c(Nc2cccc(c2)-c2cccc(c2)C#N)cc(=O)n(O)c1=O Show InChI InChI=1S/C18H14N4O3/c1-21-16(10-17(23)22(25)18(21)24)20-15-7-3-6-14(9-15)13-5-2-4-12(8-13)11-19/h2-10,20,25H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533375 (CHEMBL4514889) Show SMILES COc1ccc(c(OC)c1)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C19H19N3O5/c1-21-17(11-18(23)22(25)19(21)24)20-13-6-4-5-12(9-13)15-8-7-14(26-2)10-16(15)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533359 (CHEMBL4472917) Show SMILES COc1ccc(cc1)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-14-5-3-4-13(10-14)12-6-8-15(25-2)9-7-12/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533360 (CHEMBL4438393) Show SMILES Cn1c(Nc2ccc(cc2)-c2ccc(cc2)C#N)cc(=O)n(O)c1=O Show InChI InChI=1S/C18H14N4O3/c1-21-16(10-17(23)22(25)18(21)24)20-15-8-6-14(7-9-15)13-4-2-12(11-19)3-5-13/h2-10,20,25H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533380 (CHEMBL4578639) Show SMILES COc1cccc(OC)c1-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C19H19N3O5/c1-21-16(11-17(23)22(25)19(21)24)20-13-7-4-6-12(10-13)18-14(26-2)8-5-9-15(18)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50533377 (CHEMBL4475877) Show SMILES COc1ccc(c(OC)c1)-c1cccc(Nc2cc(=O)n(O)c(=O)[nH]2)c1 Show InChI InChI=1S/C18H17N3O5/c1-25-13-6-7-14(15(9-13)26-2)11-4-3-5-12(8-11)19-16-10-17(22)21(24)18(23)20-16/h3-10,19,24H,1-2H3,(H,20,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV integrase pre-incubated for 10 mins before addition of oligo-5'-biotin ATGTGGAAAATCTCTAGCA annealed with ACTGCTAGAGATTTTCCACAT 3'-C...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533379 (CHEMBL4463922) Show SMILES COc1ccccc1-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-13-7-5-6-12(10-13)14-8-3-4-9-15(14)25-2/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533378 (CHEMBL4440667) Show SMILES Cn1c(Nc2ccc(cc2)-c2cccc(c2)C#N)cc(=O)n(O)c1=O Show InChI InChI=1S/C18H14N4O3/c1-21-16(10-17(23)22(25)18(21)24)20-15-7-5-13(6-8-15)14-4-2-3-12(9-14)11-19/h2-10,20,25H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533368 (CHEMBL4476701) Show SMILES Cn1c(Oc2cccc(c2)-c2ccc(cc2)C#N)cc(=O)n(O)c1=O Show InChI InChI=1S/C18H13N3O4/c1-20-17(10-16(22)21(24)18(20)23)25-15-4-2-3-14(9-15)13-7-5-12(11-19)6-8-13/h2-10,24H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50533372 (CHEMBL4454510) Show SMILES COc1cccc(OC)c1-c1cccc(Nc2cc(=O)n(O)c(=O)[nH]2)c1 Show InChI InChI=1S/C18H17N3O5/c1-25-13-7-4-8-14(26-2)17(13)11-5-3-6-12(9-11)19-15-10-16(22)21(24)18(23)20-15/h3-10,19,24H,1-2H3,(H,20,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of HIV integrase pre-incubated for 10 mins before addition of oligo-5'-biotin ATGTGGAAAATCTCTAGCA annealed with ACTGCTAGAGATTTTCCACAT 3'-C...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533352 (CHEMBL4530415) Show SMILES COc1cc(OC)cc(c1)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C19H19N3O5/c1-21-17(11-18(23)22(25)19(21)24)20-14-6-4-5-12(7-14)13-8-15(26-2)10-16(9-13)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533404 (CHEMBL4445796) Show SMILES Cn1c(Nc2cccc(c2)-c2cncnc2)cc(=O)n(O)c1=O Show InChI InChI=1S/C15H13N5O3/c1-19-13(6-14(21)20(23)15(19)22)18-12-4-2-3-10(5-12)11-7-16-9-17-8-11/h2-9,18,23H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533366 (CHEMBL4540166) Show SMILES COc1ccc(c(OC)c1)-c1ccc(Nc2cc(=O)n(O)c(=O)n2C)cc1 Show InChI InChI=1S/C19H19N3O5/c1-21-17(11-18(23)22(25)19(21)24)20-13-6-4-12(5-7-13)15-9-8-14(26-2)10-16(15)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533381 (CHEMBL4531433) Show SMILES COc1ccc(cc1)-c1ccc(Oc2cc(=O)n(O)c(=O)n2C)cc1 Show InChI InChI=1S/C18H16N2O5/c1-19-17(11-16(21)20(23)18(19)22)25-15-9-5-13(6-10-15)12-3-7-14(24-2)8-4-12/h3-11,23H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533371 (CHEMBL4437185) Show SMILES Cc1noc(C)c1-c1ccc(Nc2cc(=O)n(O)c(=O)n2C)cc1 Show InChI InChI=1S/C16H16N4O4/c1-9-15(10(2)24-18-9)11-4-6-12(7-5-11)17-13-8-14(21)20(23)16(22)19(13)3/h4-8,17,23H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533362 (CHEMBL4443953) Show SMILES COc1cc(OC)cc(c1)-c1ccc(Nc2cc(=O)n(O)c(=O)n2C)cc1 Show InChI InChI=1S/C19H19N3O5/c1-21-17(11-18(23)22(25)19(21)24)20-14-6-4-12(5-7-14)13-8-15(26-2)10-16(9-13)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50533372 (CHEMBL4454510) Show SMILES COc1cccc(OC)c1-c1cccc(Nc2cc(=O)n(O)c(=O)[nH]2)c1 Show InChI InChI=1S/C18H17N3O5/c1-25-13-7-4-8-14(26-2)17(13)11-5-3-6-12(9-11)19-15-10-16(22)21(24)18(23)20-15/h3-10,19,24H,1-2H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533355 (CHEMBL4437367) Show SMILES COc1cccc(c1)-c1ccc(Nc2cc(=O)n(O)c(=O)n2C)cc1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-14-8-6-12(7-9-14)13-4-3-5-15(10-13)25-2/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533358 (CHEMBL4466948) Show SMILES Cn1c(Nc2ccc(cc2)-c2ccccc2)cc(=O)n(O)c1=O Show InChI InChI=1S/C17H15N3O3/c1-19-15(11-16(21)20(23)17(19)22)18-14-9-7-13(8-10-14)12-5-3-2-4-6-12/h2-11,18,23H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533406 (CHEMBL4471489) Show SMILES COc1cccc(c1)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-14-7-3-5-12(9-14)13-6-4-8-15(10-13)25-2/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair

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