Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 1 subunit alpha (Homo sapiens (Human)) | BDBM50582059 (CHEMBL5082582) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulator activity at human Nav1.1 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00104 BindingDB Entry DOI: 10.7270/Q29K4G3X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1 subunit alpha (Homo sapiens (Human)) | BDBM50582057 (CHEMBL5077579) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 92 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulator activity at human Nav1.1 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00104 BindingDB Entry DOI: 10.7270/Q29K4G3X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1 subunit alpha (Homo sapiens (Human)) | BDBM50582058 (CHEMBL5093878) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 102 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulator activity at human Nav1.1 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00104 BindingDB Entry DOI: 10.7270/Q29K4G3X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1 subunit alpha (Homo sapiens (Human)) | BDBM50582054 (CHEMBL5091679) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 124 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulator activity at human Nav1.1 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00104 BindingDB Entry DOI: 10.7270/Q29K4G3X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1 subunit alpha (Homo sapiens (Human)) | BDBM50582055 (CHEMBL5083412) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulator activity at human Nav1.1 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00104 BindingDB Entry DOI: 10.7270/Q29K4G3X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1 subunit alpha (Homo sapiens (Human)) | BDBM50582056 (CHEMBL5091623) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulator activity at human Nav1.1 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00104 BindingDB Entry DOI: 10.7270/Q29K4G3X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1 subunit alpha (Homo sapiens (Human)) | BDBM50582060 (CHEMBL5084333) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 172 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulator activity at human Nav1.1 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00104 BindingDB Entry DOI: 10.7270/Q29K4G3X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1 subunit alpha (Homo sapiens (Human)) | BDBM168436 (US9675591, SKA-19) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 6.90E+3 | n/a | n/a | 7.35 | 25 |
The Regents of the University of California US Patent | Assay Description All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh... | US Patent US9675591 (2017) BindingDB Entry DOI: 10.7270/Q26T0JSP | |||||||||||
More data for this Ligand-Target Pair |