Compile Data Set for Download or QSAR

Found 2266 hits of ic50 for UniProtKB: P52699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM360985 (4'-((4R,5S)-4-methyl-2- oxooxazolidin-5-yl)-N4-((R...) Show SMILES C[C@H]1NC(=O)O[C@H]1c1ccc(cc1)-c1ccc(c(c1-c1nnn[nH]1)S(N)(=O)=O)S(=O)(=O)N[C@@H]1CCNC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0410	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM360985 (4'-((4R,5S)-4-methyl-2- oxooxazolidin-5-yl)-N4-((R...) Show SMILES C[C@H]1NC(=O)O[C@H]1c1ccc(cc1)-c1ccc(c(c1-c1nnn[nH]1)S(N)(=O)=O)S(=O)(=O)N[C@@H]1CCNC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0410	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368054 (4'- (Cyclopropanesulfonamido)- 4-(methylsulfonyl)-...) Show SMILES CS(=O)(=O)c1ccc(-c2ccc(NS(=O)(=O)C3CC3)cc2)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C17H18N6O6S3/c1-30(24,25)14-9-8-13(15(16(14)31(18,26)27)17-19-22-23-20-17)10-2-4-11(5-3-10)21-32(28,29)12-6-7-12/h2-5,8-9,12,21H,6-7H2,1H3,(H2,18,26,27)(H,19,20,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0440	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361227 ((R)—N1-(1-aminopropan-2-yl)-4-(imidazo[1,2-a]...) Show SMILES C[C@H](CN)NS(=O)(=O)c1ccc(-c2cccn3ccnc23)c(-c2nn[nH]n2)c1S(N)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0540	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361227 ((R)—N1-(1-aminopropan-2-yl)-4-(imidazo[1,2-a]...) Show SMILES C[C@H](CN)NS(=O)(=O)c1ccc(-c2cccn3ccnc23)c(-c2nn[nH]n2)c1S(N)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0540	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361236 ((R)—N1-(1-aminopropan-2-yl)-4-(6-aminopyridin...) Show SMILES C[C@H](CN)NS(=O)(=O)c1ccc(-c2ccc(N)nc2)c(-c2nn[nH]n2)c1S(N)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0630	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361236 ((R)—N1-(1-aminopropan-2-yl)-4-(6-aminopyridin...) Show SMILES C[C@H](CN)NS(=O)(=O)c1ccc(-c2ccc(N)nc2)c(-c2nn[nH]n2)c1S(N)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0630	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM360850 (4-(2-amino-7- methylbenzo[d]thiazol-4-yl)- 3-(2H-t...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(N)(=O)=O)c2nc(N)sc12 Show InChI InChI=1S/C15H14N8O4S3/c1-6-2-3-8(11-12(6)28-15(16)19-11)7-4-5-9(29(17,24)25)13(30(18,26)27)10(7)14-20-22-23-21-14/h2-5H,1H3,(H2,16,19)(H2,17,24,25)(H2,18,26,27)(H,20,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0650	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM360850 (4-(2-amino-7- methylbenzo[d]thiazol-4-yl)- 3-(2H-t...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(N)(=O)=O)c2nc(N)sc12 Show InChI InChI=1S/C15H14N8O4S3/c1-6-2-3-8(11-12(6)28-15(16)19-11)7-4-5-9(29(17,24)25)13(30(18,26)27)10(7)14-20-22-23-21-14/h2-5H,1H3,(H2,16,19)(H2,17,24,25)(H2,18,26,27)(H,20,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0650	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM360980 ((R)-4'-(methylsulfonamido)-N4- (pyrrolidin-3-yl)-2...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1ccc(c(c1-c1nnn[nH]1)S(N)(=O)=O)S(=O)(=O)N[C@@H]1CCNC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0750	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361209 ((S)-4-(2-aminobenzo[d]thiazol-4-yl)-N1-((3-aminopy...) Show SMILES Nc1nc2c(cccc2s1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)NC[C@]1(N)CCNC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0750	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361209 ((S)-4-(2-aminobenzo[d]thiazol-4-yl)-N1-((3-aminopy...) Show SMILES Nc1nc2c(cccc2s1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)NC[C@]1(N)CCNC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0750	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM360980 ((R)-4'-(methylsulfonamido)-N4- (pyrrolidin-3-yl)-2...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1ccc(c(c1-c1nnn[nH]1)S(N)(=O)=O)S(=O)(=O)N[C@@H]1CCNC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0750	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361341 ((R)-N1-(4-aminobutan-2- yl)-4-(6-aminopyridin-3- y...) Show SMILES C[C@H](CCN)NS(=O)(=O)c1ccc(-c2ccc(N)nc2)c(-c2nn[nH]n2)c1S(N)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0760	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361341 ((R)-N1-(4-aminobutan-2- yl)-4-(6-aminopyridin-3- y...) Show SMILES C[C@H](CCN)NS(=O)(=O)c1ccc(-c2ccc(N)nc2)c(-c2nn[nH]n2)c1S(N)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0760	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368000 (3-(2-amino-7- methylbenzo[d]thiazol-4-yl)-6- ((R)-...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)[C@@H]2CCNC2)c2nc(N)sc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0760	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361210 ((R)-4-(2-aminobenzo[d]thiazol-4-yl)-N1-((3-aminopy...) Show SMILES Nc1nc2c(cccc2s1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)NC[C@@]1(N)CCNC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0770	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361210 ((R)-4-(2-aminobenzo[d]thiazol-4-yl)-N1-((3-aminopy...) Show SMILES Nc1nc2c(cccc2s1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)NC[C@@]1(N)CCNC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0770	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM367893 ((R)-benzyl tert-butyl (3-((2- (N,N-bis(4- methoxyb...) Show SMILES COc1ccc(CN(Cc2ccc(OC)cc2)S(=O)(=O)c2c(ccc(I)c2-c2nnn(Cc3ccc(OC)cc3)n2)S(=O)(=O)C[C@@H](CNC(=O)OC(C)(C)C)NC(=O)OCc2ccccc2)cc1 |r| Show InChI InChI=1S/C47H52IN7O11S2/c1-47(2,3)66-45(56)49-26-36(50-46(57)65-30-35-10-8-7-9-11-35)31-67(58,59)41-25-24-40(48)42(44-51-53-55(52-44)29-34-16-22-39(64-6)23-17-34)43(41)68(60,61)54(27-32-12-18-37(62-4)19-13-32)28-33-14-20-38(63-5)21-15-33/h7-25,36H,26-31H2,1-6H3,(H,49,56)(H,50,57)/t36-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0850	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368120 (3-(2-(2-amino-1,1- difluoroethyl)-1H- benzo[d]imid...) Show SMILES NCCS(=O)(=O)c1ccc(-c2cccc3[nH]c(nc23)C(F)(F)CN)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C18H19F2N9O4S2/c19-18(20,8-22)17-24-11-3-1-2-10(14(11)25-17)9-4-5-12(34(30,31)7-6-21)15(35(23,32)33)13(9)16-26-28-29-27-16/h1-5H,6-8,21-22H2,(H,24,25)(H2,23,32,33)(H,26,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0870	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368052 (3-(2-aminobenzo[d]thiazol- 4-yl)-6-(methylsulfonyl...) Show SMILES CS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C15H13N7O4S3/c1-28(23,24)10-6-5-7(8-3-2-4-9-12(8)18-15(16)27-9)11(13(10)29(17,25)26)14-19-21-22-20-14/h2-6H,1H3,(H2,16,18)(H2,17,25,26)(H,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0910	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368006 (3-(2-amino-7- methylbenzo[d]thiazol-4-yl)-6- (meth...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(C)(=O)=O)c2nc(N)sc12 Show InChI InChI=1S/C16H15N7O4S3/c1-7-3-4-9(12-13(7)28-16(17)19-12)8-5-6-10(29(2,24)25)14(30(18,26)27)11(8)15-20-22-23-21-15/h3-6H,1-2H3,(H2,17,19)(H2,18,26,27)(H,20,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0940	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM367903 (6-(2-aminoethylsulfonyl)-3-(2-(methylamino)benzo[d...) Show SMILES CNc1nc2c(cccc2s1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)CCN Show InChI InChI=1S/C17H18N8O4S3/c1-20-17-21-14-10(3-2-4-11(14)30-17)9-5-6-12(31(26,27)8-7-18)15(32(19,28)29)13(9)16-22-24-25-23-16/h2-6H,7-8,18H2,1H3,(H,20,21)(H2,19,28,29)(H,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0990	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361042 (N1-(2-aminoethyl)-4-(1H-benzo[d]imidazol-4-yl)-3-(...) Show SMILES NCCNS(=O)(=O)c1ccc(-c2cccc3[nH]cnc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C16H17N9O4S2/c17-6-7-21-31(28,29)12-5-4-9(10-2-1-3-11-14(10)20-8-19-11)13(15(12)30(18,26)27)16-22-24-25-23-16/h1-5,8,21H,6-7,17H2,(H,19,20)(H2,18,26,27)(H,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.102	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361042 (N1-(2-aminoethyl)-4-(1H-benzo[d]imidazol-4-yl)-3-(...) Show SMILES NCCNS(=O)(=O)c1ccc(-c2cccc3[nH]cnc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C16H17N9O4S2/c17-6-7-21-31(28,29)12-5-4-9(10-2-1-3-11-14(10)20-8-19-11)13(15(12)30(18,26)27)16-22-24-25-23-16/h1-5,8,21H,6-7,17H2,(H,19,20)(H2,18,26,27)(H,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.102	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361273 (US10221163, Example 430 | US10544130, Example 430) Show SMILES NCC(CN)NS(=O)(=O)c1ccc(-c2cccc3ccc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C19H22N10O4S2/c20-8-11(9-21)27-35(32,33)14-6-5-12(13-3-1-2-10-4-7-15(22)24-17(10)13)16(18(14)34(23,30)31)19-25-28-29-26-19/h1-7,11,27H,8-9,20-21H2,(H2,22,24)(H2,23,30,31)(H,25,26,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.102	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361273 (US10221163, Example 430 | US10544130, Example 430) Show SMILES NCC(CN)NS(=O)(=O)c1ccc(-c2cccc3ccc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C19H22N10O4S2/c20-8-11(9-21)27-35(32,33)14-6-5-12(13-3-1-2-10-4-7-15(22)24-17(10)13)16(18(14)34(23,30)31)19-25-28-29-26-19/h1-7,11,27H,8-9,20-21H2,(H2,22,24)(H2,23,30,31)(H,25,26,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.102	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361279 (US10221163, Example 436 | US10544130, Example 436) Show SMILES NCC(CN)NS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C17H20N10O4S3/c18-6-8(7-19)25-34(30,31)12-5-4-9(10-2-1-3-11-14(10)22-17(20)32-11)13(15(12)33(21,28)29)16-23-26-27-24-16/h1-5,8,25H,6-7,18-19H2,(H2,20,22)(H2,21,28,29)(H,23,24,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.103	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361279 (US10221163, Example 436 | US10544130, Example 436) Show SMILES NCC(CN)NS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C17H20N10O4S3/c18-6-8(7-19)25-34(30,31)12-5-4-9(10-2-1-3-11-14(10)22-17(20)32-11)13(15(12)33(21,28)29)16-23-26-27-24-16/h1-5,8,25H,6-7,18-19H2,(H2,20,22)(H2,21,28,29)(H,23,24,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.103	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368058 (3-((4′-(Cyclopropanesulfonamido)-3-sulfamoyl...) Show SMILES NS(=O)(=O)c1c(ccc(-c2ccc(NS(=O)(=O)C3CC3)cc2)c1-c1nn[nH]n1)S(=O)(=O)C1CN(C1)C(=O)NC1CC1 Show InChI InChI=1S/C23H26N8O7S3/c24-40(35,36)21-19(39(33,34)17-11-31(12-17)23(32)25-14-5-6-14)10-9-18(20(21)22-26-29-30-27-22)13-1-3-15(4-2-13)28-41(37,38)16-7-8-16/h1-4,9-10,14,16-17,28H,5-8,11-12H2,(H,25,32)(H2,24,35,36)(H,26,27,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.103	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368049 (4-(methylsulfonyl)-4′-(piperidin-4-yl)-2-(1H...) Show SMILES CS(=O)(=O)c1ccc(-c2ccc(cc2)C2CCNCC2)c(-c2nnn[nH]2)c1S(N)(=O)=O Show InChI InChI=1S/C19H22N6O4S2/c1-30(26,27)16-7-6-15(17(18(16)31(20,28)29)19-22-24-25-23-19)14-4-2-12(3-5-14)13-8-10-21-11-9-13/h2-7,13,21H,8-11H2,1H3,(H2,20,28,29)(H,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.103	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM360855 (4-(2-aminobenzo[d]oxazol- 4-yl)-N1-(2-aminoethyl)-...) Show SMILES NCCNS(=O)(=O)c1ccc(-c2cccc3oc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C16H17N9O5S2/c17-6-7-20-32(28,29)11-5-4-8(9-2-1-3-10-13(9)21-16(18)30-10)12(14(11)31(19,26)27)15-22-24-25-23-15/h1-5,20H,6-7,17H2,(H2,18,21)(H2,19,26,27)(H,22,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.105	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM367839 ((2-amino-3- cyanophenyl) boronic acid | US10227331...) Show SMILES Nc1c(cccc1B(O)O)C#N Show InChI InChI=1S/C7H7BN2O2/c9-4-5-2-1-3-6(7(5)10)8(11)12/h1-3,11-12H,10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.105	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361044 ((S)—N1-(1-amino-3-hydroxypropan-2-yl)-4-(2-am...) Show SMILES NCC(CO)NS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.109	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361044 ((S)—N1-(1-amino-3-hydroxypropan-2-yl)-4-(2-am...) Show SMILES NCC(CO)NS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.109	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368001 (3-(2-amino-7- methylbenzo[d]thiazol-4-yl)-6- ((S)-...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)[C@H]2CCNC2)c2nc(N)sc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.109	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361068 ((R)-N4-(pyrrolidin-3-yl)-2-(2H- tetrazol-5-yl)-3'-...) Show SMILES NS(=O)(=O)c1c(ccc(-c2cccc(c2)-c2nc[nH]n2)c1-c1nn[nH]n1)S(=O)(=O)N[C@@H]1CCNC1 Show InChI InChI=1S/C19H20N10O4S2/c20-34(30,31)17-15(35(32,33)27-13-6-7-21-9-13)5-4-14(16(17)19-25-28-29-26-19)11-2-1-3-12(8-11)18-22-10-23-24-18/h1-5,8,10,13,21,27H,6-7,9H2,(H2,20,30,31)(H,22,23,24)(H,25,26,28,29)/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361068 ((R)-N4-(pyrrolidin-3-yl)-2-(2H- tetrazol-5-yl)-3'-...) Show SMILES NS(=O)(=O)c1c(ccc(-c2cccc(c2)-c2nc[nH]n2)c1-c1nn[nH]n1)S(=O)(=O)N[C@@H]1CCNC1 Show InChI InChI=1S/C19H20N10O4S2/c20-34(30,31)17-15(35(32,33)27-13-6-7-21-9-13)5-4-14(16(17)19-25-28-29-26-19)11-2-1-3-12(8-11)18-22-10-23-24-18/h1-5,8,10,13,21,27H,6-7,9H2,(H2,20,30,31)(H,22,23,24)(H,25,26,28,29)/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361314 ((R)-2-((4′-(N-(pyrrolidin-3-yl)sulfamoyl)-3&...) Show SMILES NC(=O)c1csc(Nc2cccc(c2)-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)N[C@@H]2CCNC2)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.111	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361314 ((R)-2-((4′-(N-(pyrrolidin-3-yl)sulfamoyl)-3&...) Show SMILES NC(=O)c1csc(Nc2cccc(c2)-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)N[C@@H]2CCNC2)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.111	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361080 (US10221163, Example 237 | US10544130, Example 237) Show SMILES C[C@H](CN)NS(=O)(=O)c1ccc(-c2cccc3[nH]nnc23)c(-c2nn[nH]n2)c1S(N)(=O)=O |r| Show InChI InChI=1S/C16H16N10O4S2/c1-8(7-17)23-32(29,30)12-6-5-9(10-3-2-4-11-14(10)20-24-19-11)13(15(12)31(18,27)28)16-21-25-26-22-16/h2-6,8,23H,7,17H2,1H3,(H2,18,27,28)/b10-9+/t8-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361080 (US10221163, Example 237 | US10544130, Example 237) Show SMILES C[C@H](CN)NS(=O)(=O)c1ccc(-c2cccc3[nH]nnc23)c(-c2nn[nH]n2)c1S(N)(=O)=O |r| Show InChI InChI=1S/C16H16N10O4S2/c1-8(7-17)23-32(29,30)12-6-5-9(10-3-2-4-11-14(10)20-24-19-11)13(15(12)31(18,27)28)16-21-25-26-22-16/h2-6,8,23H,7,17H2,1H3,(H2,18,27,28)/b10-9+/t8-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361129 ((R)-4-(2-aminoquinolin- 8-yl)-N1-(pyrrolidin-3- yl...) Show SMILES Nc1ccc2cccc(-c3ccc(c(c3-c3nn[nH]n3)S(N)(=O)=O)S(=O)(=O)N[C@@H]3CCNC3)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.122	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361129 ((R)-4-(2-aminoquinolin- 8-yl)-N1-(pyrrolidin-3- yl...) Show SMILES Nc1ccc2cccc(-c3ccc(c(c3-c3nn[nH]n3)S(N)(=O)=O)S(=O)(=O)N[C@@H]3CCNC3)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.122	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM367851 (2-amino-4-(4-(azetidin-3-ylsulfonyl)-3-sulfamoyl-2...) Show SMILES Nc1nc2c(ccc(C(O)=O)c2s1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)C1CNC1 Show InChI InChI=1S/C18H16N8O6S3/c19-18-22-13-9(1-2-10(17(27)28)14(13)33-18)8-3-4-11(34(29,30)7-5-21-6-7)15(35(20,31)32)12(8)16-23-25-26-24-16/h1-4,7,21H,5-6H2,(H2,19,22)(H,27,28)(H2,20,31,32)(H,23,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.126	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368094 (6-((S)-3-amino-2-hydroxypropylsulfonyl)-3-(2-amino...) Show SMILES NC[C@H](O)CS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.126	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368058 (3-((4′-(Cyclopropanesulfonamido)-3-sulfamoyl...) Show SMILES NS(=O)(=O)c1c(ccc(-c2ccc(NS(=O)(=O)C3CC3)cc2)c1-c1nn[nH]n1)S(=O)(=O)C1CN(C1)C(=O)NC1CC1 Show InChI InChI=1S/C23H26N8O7S3/c24-40(35,36)21-19(39(33,34)17-11-31(12-17)23(32)25-14-5-6-14)10-9-18(20(21)22-26-29-30-27-22)13-1-3-15(4-2-13)28-41(37,38)16-7-8-16/h1-4,9-10,14,16-17,28H,5-8,11-12H2,(H,25,32)(H2,24,35,36)(H,26,27,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.126	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361172 (4-(2-Amino-7-methyl-1H-benzo[d]imidazol-4-yl)-N1-(...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)NCCN)c2nc(N)[nH]c12 Show InChI InChI=1S/C17H20N10O4S2/c1-8-2-3-10(14-13(8)22-17(19)23-14)9-4-5-11(33(30,31)21-7-6-18)15(32(20,28)29)12(9)16-24-26-27-25-16/h2-5,21H,6-7,18H2,1H3,(H3,19,22,23)(H2,20,28,29)(H,24,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.128	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361172 (4-(2-Amino-7-methyl-1H-benzo[d]imidazol-4-yl)-N1-(...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)NCCN)c2nc(N)[nH]c12 Show InChI InChI=1S/C17H20N10O4S2/c1-8-2-3-10(14-13(8)22-17(19)23-14)9-4-5-11(33(30,31)21-7-6-18)15(32(20,28)29)12(9)16-24-26-27-25-16/h2-5,21H,6-7,18H2,1H3,(H3,19,22,23)(H2,20,28,29)(H,24,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.128	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM367884 (6-(2-aminoethylsulfonyl)-3-(2- aminoquinolin-8-yl)...) Show SMILES NCCS(=O)(=O)c1ccc(-c2cccc3ccc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C18H18N8O4S2/c19-8-9-31(27,28)13-6-5-11(12-3-1-2-10-4-7-14(20)22-16(10)12)15(17(13)32(21,29)30)18-23-25-26-24-18/h1-7H,8-9,19H2,(H2,20,22)(H2,21,29,30)(H,23,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.129	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair

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