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Compile Data Set for Download or QSAR

Found 2 hits of kd for UniProtKB: P30281   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3


(Homo sapiens (Human))		BDBM50538150
PNG
(CHEMBL4647703)
Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3cccc(NC(C)=O)c3)n2)nc1
Show InChI InChI=1S/C22H25ClN8O/c1-15(32)26-16-4-3-5-17(12-16)27-21-19(23)14-25-22(29-21)28-20-7-6-18(13-24-20)31-10-8-30(2)9-11-31/h3-7,12-14H,8-11H2,1-2H3,(H,26,32)(H2,24,25,27,28,29)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 71n/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant full-length GFP-fused CDK6/His-tagged cyclin D3 (unknown origin) expressed in HEK293T cells measured after 30 mins by...

J Med Chem 63: 3327-3347 (2020)


Article DOI: 10.1021/acs.jmedchem.9b02121
BindingDB Entry DOI: 10.7270/Q2N87F9B
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D3


(Homo sapiens (Human))		BDBM50519158
PNG
(CHEMBL4445812)
Show SMILES Clc1ccc(cc1Cl)C(=O)Nc1ccc2cc(ccc2c1)C(=O)Nc1nccs1
Show InChI InChI=1S/C21H13Cl2N3O2S/c22-17-6-4-15(11-18(17)23)19(27)25-16-5-3-12-9-14(2-1-13(12)10-16)20(28)26-21-24-7-8-29-21/h1-11H,(H,25,27)(H,24,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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UniChem
Article
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n/an/an/a 8.02E+3n/an/an/an/an/a



Chengdu University

Curated by ChEMBL


Assay Description
Binding affinity to wild-type human full length CDK4/cyclinD3 (M1 to E303 residues) expressed in mammalian expression system measured after 1 hr by k...

J Med Chem 62: 7697-7707 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00353
BindingDB Entry DOI: 10.7270/Q2X06BF7
More data for this
Ligand-Target Pair