Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50065646 (CHEMBL3087181) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.214 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of rat MAGL | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50160284 (CHEMBL3785379) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of rat MAGL | J Med Chem 59: 2612-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01812 BindingDB Entry DOI: 10.7270/Q21R6SC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50450752 (CHEMBL4216513) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.269 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of rat MAGL | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50102829 (CHEMBL3356956) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.589 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of rat MAGL | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50099618 (CHEMBL1232635) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of rat MAGL | J Med Chem 63: 5783-5796 (2020) Article DOI: 10.1021/acs.jmedchem.9b02137 BindingDB Entry DOI: 10.7270/Q2GQ7288 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50099618 (CHEMBL1232635) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of rat MAGL | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50160284 (CHEMBL3785379) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of MAGL in rat brain membranes preincubated for 20 mins followed by fluorophosphonate-rhodamine addition measured after 30 mins by competi... | J Med Chem 59: 2612-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01812 BindingDB Entry DOI: 10.7270/Q21R6SC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514172 (CHEMBL4536072) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM179950 (US9133148, 3a) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of rat MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assay | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514166 (CHEMBL4448448) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514173 (CHEMBL4463191) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50359050 (CHEMBL1922513) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol... | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520895 (CHEMBL4472033) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514167 (CHEMBL4560077) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM60622 (BDBM50300355 | US11753371, Compound JZL-184 | US91...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
University of M£nster Curated by ChEMBL | Assay Description Inhibition of rat MAGL expressed in monkey COS7 cells | Eur J Med Chem 63: 64-75 (2013) Article DOI: 10.1016/j.ejmech.2013.01.050 BindingDB Entry DOI: 10.7270/Q2377B2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520905 (CHEMBL4437385) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50435396 (CHEMBL2391916) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520885 (CHEMBL4521157) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM179929 (US9133148, 1a) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of rat MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assay | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50450761 (CHEMBL4202705) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol... | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514173 (CHEMBL4463191) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL C208A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520890 (CHEMBL4445089) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514173 (CHEMBL4463191) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL C201A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514170 (CHEMBL4515209) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514182 (CHEMBL3219170) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50359050 (CHEMBL1922513) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain Curated by ChEMBL | Assay Description Inhibition of rat recombinant N-terminal his-tagged MAGL expressed in Escherichia coli DH5alpha assessed as 2-oleoylglycerol hydrolysis after 10 mins... | Bioorg Med Chem Lett 21: 7321-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.026 BindingDB Entry DOI: 10.7270/Q2B27VPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50359050 (CHEMBL1922513) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM61908 (2-methyl-1,2-benzothiazol-3-one | KUC103657N | acs...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50435396 (CHEMBL2391916) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL C208A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520896 (CHEMBL4463729) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514166 (CHEMBL4448448) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL C208A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50359049 (CHEMBL1922512) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain Curated by ChEMBL | Assay Description Inhibition of rat recombinant N-terminal his-tagged MAGL expressed in Escherichia coli DH5alpha assessed as 2-oleoylglycerol hydrolysis after 10 mins... | Bioorg Med Chem Lett 21: 7321-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.026 BindingDB Entry DOI: 10.7270/Q2B27VPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM66023 (2-octyl-1,2-thiazol-3-one | 2-octyl-3-isothiazolon...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol... | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM81363 (Pristimerin) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | 37 |
University of California Irvine | Assay Description Purified recombinant rat MGL was prepared and enzyme activity was assayed. | Chem Biol 16: 1045-52 (2009) Article DOI: 10.1016/j.chembiol.2009.09.012 BindingDB Entry DOI: 10.7270/Q2HH6HJ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50481947 (CHEBI:8416 | GNF-Pf-476 | PRISTIMERIN | Pristimeri...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant rat MAGL by LC-MS analysis | Citation and Details Article DOI: 10.1016/j.bmcl.2021.127986 BindingDB Entry DOI: 10.7270/Q2D222D0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50450775 (CHEMBL4207055 | med.21724, Compound 142) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of recombinant rat MAGL expressed in Escherichia coli using 2-AG as substrate | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514180 (CHEMBL4439900) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520901 (CHEMBL4472005) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520904 (CHEMBL4541769) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520894 (CHEMBL4540953) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520888 (CHEMBL4473440) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520898 (CHEMBL4435037) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520892 (CHEMBL4548730) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514166 (CHEMBL4448448) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL C201A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520887 (CHEMBL4565696) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50514179 (CHEMBL4558017) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad... | J Med Chem 63: 1261-1280 (2020) Article DOI: 10.1021/acs.jmedchem.9b01679 BindingDB Entry DOI: 10.7270/Q2377D2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM60419 (BDBM50295658 | NAM) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
University of M£nster Curated by ChEMBL | Assay Description Inhibition of MAGL in rat cerebellar membranes | Eur J Med Chem 63: 64-75 (2013) Article DOI: 10.1016/j.ejmech.2013.01.050 BindingDB Entry DOI: 10.7270/Q2377B2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM60419 (BDBM50295658 | NAM) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Chemical and Pharmaceutical Sciences, University of Ferrara , 44121 Ferrara, Italy. Curated by ChEMBL | Assay Description Inhibition of MAGL from Wistar rat brain using 2-monooleoyl[1,2,3-H]glycerol as substrate | J Med Chem 61: 1340-1354 (2018) Article DOI: 10.1021/acs.jmedchem.7b01845 BindingDB Entry DOI: 10.7270/Q2JM2D3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM60419 (BDBM50295658 | NAM) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille Curated by ChEMBL | Assay Description Inhibition of rat cerebellar membranes MAGL-like activity preincubated for 30 mins followed by 2-AG substrate addition after 90 mins by HPLC analysis | J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50520891 (CHEMBL4557262) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
MAK Scientific LLC Curated by ChEMBL | Assay Description Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte... | Bioorg Med Chem 27: 55-64 (2019) Article DOI: 10.1016/j.bmc.2018.11.003 BindingDB Entry DOI: 10.7270/Q2XD153X | |||||||||||
More data for this Ligand-Target Pair |
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