Compile Data Set for Download or QSAR

Found 314 hits of ic50 for UniProtKB: P43004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50327884 ((2S,3S)-2-amino-3-(3-(4-(trifluoromethyl)benzamido...) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)c2ccc(cc2)C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C19H17F3N2O6/c20-19(21,22)12-6-4-11(5-7-12)16(25)24-13-3-1-2-10(8-13)9-30-15(18(28)29)14(23)17(26)27/h1-8,14-15H,9,23H2,(H,24,25)(H,26,27)(H,28,29)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50327884 ((2S,3S)-2-amino-3-(3-(4-(trifluoromethyl)benzamido...) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)c2ccc(cc2)C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C19H17F3N2O6/c20-19(21,22)12-6-4-11(5-7-12)16(25)24-13-3-1-2-10(8-13)9-30-15(18(28)29)14(23)17(26)27/h1-8,14-15H,9,23H2,(H,24,25)(H,26,27)(H,28,29)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366648 (CHEMBL4173045) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)c2cccc(c2)C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C19H17F3N2O6/c20-19(21,22)12-5-2-4-11(8-12)16(25)24-13-6-1-3-10(7-13)9-30-15(18(28)29)14(23)17(26)27/h1-8,14-15H,9,23H2,(H,24,25)(H,26,27)(H,28,29)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50327884 ((2S,3S)-2-amino-3-(3-(4-(trifluoromethyl)benzamido...) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)c2ccc(cc2)C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C19H17F3N2O6/c20-19(21,22)12-6-4-11(5-7-12)16(25)24-13-3-1-2-10(8-13)9-30-15(18(28)29)14(23)17(26)27/h1-8,14-15H,9,23H2,(H,24,25)(H,26,27)(H,28,29)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of EAAT2 (unknown origin) transiently expressed in COS1 cells by [14C]glutamate based uptake assay				J Med Chem 63: 3834-3867 (2020) Article DOI: 10.1021/acs.jmedchem.9b01237 BindingDB Entry DOI: 10.7270/Q26113PD
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50327884 ((2S,3S)-2-amino-3-(3-(4-(trifluoromethyl)benzamido...) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)c2ccc(cc2)C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C19H17F3N2O6/c20-19(21,22)12-6-4-11(5-7-12)16(25)24-13-3-1-2-10(8-13)9-30-15(18(28)29)14(23)17(26)27/h1-8,14-15H,9,23H2,(H,24,25)(H,26,27)(H,28,29)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation counting				J Med Chem 53: 7236-50 (2010) Article DOI: 10.1021/jm100959g BindingDB Entry DOI: 10.7270/Q27081NR
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366648 (CHEMBL4173045) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)c2cccc(c2)C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C19H17F3N2O6/c20-19(21,22)12-5-2-4-11(8-12)16(25)24-13-6-1-3-10(7-13)9-30-15(18(28)29)14(23)17(26)27/h1-8,14-15H,9,23H2,(H,24,25)(H,26,27)(H,28,29)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366616 (CHEMBL4176427) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)CCc2ccc(cc2)C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C21H21F3N2O6/c22-21(23,24)14-7-4-12(5-8-14)6-9-16(27)26-15-3-1-2-13(10-15)11-32-18(20(30)31)17(25)19(28)29/h1-5,7-8,10,17-18H,6,9,11,25H2,(H,26,27)(H,28,29)(H,30,31)/t17-,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366616 (CHEMBL4176427) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)CCc2ccc(cc2)C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C21H21F3N2O6/c22-21(23,24)14-7-4-12(5-8-14)6-9-16(27)26-15-3-1-2-13(10-15)11-32-18(20(30)31)17(25)19(28)29/h1-5,7-8,10,17-18H,6,9,11,25H2,(H,26,27)(H,28,29)(H,30,31)/t17-,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366614 (CHEMBL4176482) Show SMILES N[C@@H]([C@H](OCc1ccccc1)C(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O |r| Show InChI InChI=1S/C23H19BrF2N2O5/c24-16-10-17(25)18(26)11-19(16)33-15-8-6-14(7-9-15)28-22(29)21(20(27)23(30)31)32-12-13-4-2-1-3-5-13/h1-11,20-21H,12,27H2,(H,28,29)(H,30,31)/t20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366614 (CHEMBL4176482) Show SMILES N[C@@H]([C@H](OCc1ccccc1)C(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O |r| Show InChI InChI=1S/C23H19BrF2N2O5/c24-16-10-17(25)18(26)11-19(16)33-15-8-6-14(7-9-15)28-22(29)21(20(27)23(30)31)32-12-13-4-2-1-3-5-13/h1-11,20-21H,12,27H2,(H,28,29)(H,30,31)/t20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366609 (CHEMBL4177507) Show SMILES N[C@@H]([C@H](OCc1ccccc1)C(=O)Nc1ccc-2c(Cc3ccccc-23)c1)C(O)=O |r| Show InChI InChI=1S/C24H22N2O4/c25-21(24(28)29)22(30-14-15-6-2-1-3-7-15)23(27)26-18-10-11-20-17(13-18)12-16-8-4-5-9-19(16)20/h1-11,13,21-22H,12,14,25H2,(H,26,27)(H,28,29)/t21-,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366609 (CHEMBL4177507) Show SMILES N[C@@H]([C@H](OCc1ccccc1)C(=O)Nc1ccc-2c(Cc3ccccc-23)c1)C(O)=O |r| Show InChI InChI=1S/C24H22N2O4/c25-21(24(28)29)22(30-14-15-6-2-1-3-7-15)23(27)26-18-10-11-20-17(13-18)12-16-8-4-5-9-19(16)20/h1-11,13,21-22H,12,14,25H2,(H,26,27)(H,28,29)/t21-,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410456 (CHEMBL2113122) Show SMILES N[C@@H](CC(=O)Nc1ccc(cc1)-c1cccc(c1)C(F)(F)F)C(O)=O |r| Show InChI InChI=1S/C17H15F3N2O3/c18-17(19,20)12-3-1-2-11(8-12)10-4-6-13(7-5-10)22-15(23)9-14(21)16(24)25/h1-8,14H,9,21H2,(H,22,23)(H,24,25)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM86712 (CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...) Show SMILES N[C@@H](CC(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O |r| Show InChI InChI=1S/C16H13BrF2N2O4/c17-10-5-11(18)12(19)6-14(10)25-9-3-1-8(2-4-9)21-15(22)7-13(20)16(23)24/h1-6,13H,7,20H2,(H,21,22)(H,23,24)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM86712 (CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...) Show SMILES N[C@@H](CC(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O |r| Show InChI InChI=1S/C16H13BrF2N2O4/c17-10-5-11(18)12(19)6-14(10)25-9-3-1-8(2-4-9)21-15(22)7-13(20)16(23)24/h1-6,13H,7,20H2,(H,21,22)(H,23,24)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM86712 (CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...) Show SMILES N[C@@H](CC(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O |r| Show InChI InChI=1S/C16H13BrF2N2O4/c17-10-5-11(18)12(19)6-14(10)25-9-3-1-8(2-4-9)21-15(22)7-13(20)16(23)24/h1-6,13H,7,20H2,(H,21,22)(H,23,24)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410463 (CHEMBL2113115) Show SMILES N[C@@H](CC(=O)Nc1ccc-2c(Cc3cc(F)ccc-23)c1)C(O)=O |r| Show InChI InChI=1S/C17H15FN2O3/c18-11-1-3-13-9(6-11)5-10-7-12(2-4-14(10)13)20-16(21)8-15(19)17(22)23/h1-4,6-7,15H,5,8,19H2,(H,20,21)(H,22,23)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366656 (CHEMBL4162363) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C19H17F3N2O6/c20-19(21,22)13-7-2-1-6-12(13)16(25)24-11-5-3-4-10(8-11)9-30-15(18(28)29)14(23)17(26)27/h1-8,14-15H,9,23H2,(H,24,25)(H,26,27)(H,28,29)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366656 (CHEMBL4162363) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C19H17F3N2O6/c20-19(21,22)13-7-2-1-6-12(13)16(25)24-11-5-3-4-10(8-11)9-30-15(18(28)29)14(23)17(26)27/h1-8,14-15H,9,23H2,(H,24,25)(H,26,27)(H,28,29)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410455 (CHEMBL2113116) Show SMILES N[C@@H](CC(=O)Nc1ccc-2c(Cc3cc(Cl)ccc-23)c1)C(O)=O |r| Show InChI InChI=1S/C17H15ClN2O3/c18-11-1-3-13-9(6-11)5-10-7-12(2-4-14(10)13)20-16(21)8-15(19)17(22)23/h1-4,6-7,15H,5,8,19H2,(H,20,21)(H,22,23)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM86713 (WAY 213394 | WAY-213394) Show SMILES Cc1ccccc1-c1ccc(NC(=O)C[C@H](N)C(O)=O)cc1 Show InChI InChI=1S/C17H18N2O3/c1-11-4-2-3-5-14(11)12-6-8-13(9-7-12)19-16(20)10-15(18)17(21)22/h2-9,15H,10,18H2,1H3,(H,19,20)(H,21,22)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM86714 (WAY 212922 | WAY-212922) Show SMILES N[C@@H](CC(=O)Nc1ccc-2c(Cc3cc(ccc-23)C(F)(F)F)c1)C(O)=O Show InChI InChI=1S/C18H15F3N2O3/c19-18(20,21)11-1-3-13-9(6-11)5-10-7-12(2-4-14(10)13)23-16(24)8-15(22)17(25)26/h1-4,6-7,15H,5,8,22H2,(H,23,24)(H,25,26)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410461 (CHEMBL2113126) Show SMILES Cc1cc(NC(=O)C[C@H](N)C(O)=O)ccc1-c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C17H16Cl2N2O3/c1-9-6-11(21-16(22)8-15(20)17(23)24)3-4-12(9)10-2-5-13(18)14(19)7-10/h2-7,15H,8,20H2,1H3,(H,21,22)(H,23,24)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410457 (CHEMBL2113112) Show SMILES Cc1cc(NC(=O)C[C@H](N)C(O)=O)ccc1-c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C18H17F3N2O3/c1-10-7-13(23-16(24)9-15(22)17(25)26)5-6-14(10)11-3-2-4-12(8-11)18(19,20)21/h2-8,15H,9,22H2,1H3,(H,23,24)(H,25,26)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366626 (CHEMBL4165811) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)Cc2ccc(cc2)C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C20H19F3N2O6/c21-20(22,23)13-6-4-11(5-7-13)9-15(26)25-14-3-1-2-12(8-14)10-31-17(19(29)30)16(24)18(27)28/h1-8,16-17H,9-10,24H2,(H,25,26)(H,27,28)(H,29,30)/t16-,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366626 (CHEMBL4165811) Show SMILES N[C@@H]([C@H](OCc1cccc(NC(=O)Cc2ccc(cc2)C(F)(F)F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C20H19F3N2O6/c21-20(22,23)13-6-4-11(5-7-13)9-15(26)25-14-3-1-2-12(8-14)10-31-17(19(29)30)16(24)18(27)28/h1-8,16-17H,9-10,24H2,(H,25,26)(H,27,28)(H,29,30)/t16-,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410460 (CHEMBL2113121) Show SMILES N[C@@H](CC(=O)Nc1ccc(Oc2ccc(F)c(F)c2)cc1)C(O)=O |r| Show InChI InChI=1S/C16H14F2N2O4/c17-12-6-5-11(7-13(12)18)24-10-3-1-9(2-4-10)20-15(21)8-14(19)16(22)23/h1-7,14H,8,19H2,(H,20,21)(H,22,23)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM86712 (CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...) Show SMILES N[C@@H](CC(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O |r| Show InChI InChI=1S/C16H13BrF2N2O4/c17-10-5-11(18)12(19)6-14(10)25-9-3-1-8(2-4-9)21-15(22)7-13(20)16(23)24/h1-6,13H,7,20H2,(H,21,22)(H,23,24)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in oocytes expressing in human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410452 (CHEMBL2113125) Show SMILES Cc1cc(NC(=O)C[C@H](N)C(O)=O)ccc1-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C17H17ClN2O3/c1-10-8-13(20-16(21)9-15(19)17(22)23)6-7-14(10)11-2-4-12(18)5-3-11/h2-8,15H,9,19H2,1H3,(H,20,21)(H,22,23)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50173936 (2-Amino-N-(3-methyl-biphenyl-4-yl)-succinamic acid...) Show SMILES Cc1cc(ccc1NC(=O)CC(N)C(O)=O)-c1ccccc1 Show InChI InChI=1S/C17H18N2O3/c1-11-9-13(12-5-3-2-4-6-12)7-8-15(11)19-16(20)10-14(18)17(21)22/h2-9,14H,10,18H2,1H3,(H,19,20)(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410465 (CHEMBL2113113) Show SMILES N[C@@H](CC(=O)Nc1ccc(-c2ccc(F)c(Cl)c2)c(c1)C(F)(F)F)C(O)=O |r| Show InChI InChI=1S/C17H13ClF4N2O3/c18-12-5-8(1-4-13(12)19)10-3-2-9(6-11(10)17(20,21)22)24-15(25)7-14(23)16(26)27/h1-6,14H,7,23H2,(H,24,25)(H,26,27)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410459 (CHEMBL2113117) Show SMILES N[C@@H](CC(=O)Nc1ccc-2c(Cc3cc(Br)ccc-23)c1)C(O)=O |r| Show InChI InChI=1S/C17H15BrN2O3/c18-11-1-3-13-9(6-11)5-10-7-12(2-4-14(10)13)20-16(21)8-15(19)17(22)23/h1-4,6-7,15H,5,8,19H2,(H,20,21)(H,22,23)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50561801 (CHEMBL4759043) Show SMILES OC(=O)C(F)(F)F.Cc1ccc(cc1)S(=O)(=O)n1cc(-c2ccsc2)c2ccc(CO[C@@H]([C@H](N)C(O)=O)C(O)=O)cc12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00342 BindingDB Entry DOI: 10.7270/Q2WH2TQZ
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50561801 (CHEMBL4759043) Show SMILES OC(=O)C(F)(F)F.Cc1ccc(cc1)S(=O)(=O)n1cc(-c2ccsc2)c2ccc(CO[C@@H]([C@H](N)C(O)=O)C(O)=O)cc12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00342 BindingDB Entry DOI: 10.7270/Q2WH2TQZ
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410450 (CHEMBL2113118) Show SMILES N[C@@H](CC(=O)Nc1ccc-2c(Cc3c-2cc(Cl)cc3Cl)c1)C(O)=O |r| Show InChI InChI=1S/C17H14Cl2N2O3/c18-9-5-12-11-2-1-10(21-16(22)7-15(20)17(23)24)3-8(11)4-13(12)14(19)6-9/h1-3,5-6,15H,4,7,20H2,(H,21,22)(H,23,24)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410453 (CHEMBL2113128) Show SMILES N[C@@H](CC(=O)Nc1ccc(cc1)-c1ccc2ccccc2c1)C(O)=O |r| Show InChI InChI=1S/C20H18N2O3/c21-18(20(24)25)12-19(23)22-17-9-7-14(8-10-17)16-6-5-13-3-1-2-4-15(13)11-16/h1-11,18H,12,21H2,(H,22,23)(H,24,25)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410454 (CHEMBL2113124) Show SMILES Cc1cc(NC(=O)C[C@H](N)C(O)=O)ccc1-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C18H17F3N2O3/c1-10-8-13(23-16(24)9-15(22)17(25)26)6-7-14(10)11-2-4-12(5-3-11)18(19,20)21/h2-8,15H,9,22H2,1H3,(H,23,24)(H,25,26)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50173917 (2-Amino-N-(10-ethyl-10H-phenoxazin-2-yl)-succinami...) Show SMILES CCN1c2ccccc2Oc2ccc(NC(=O)CC(N)C(O)=O)cc12 Show InChI InChI=1S/C18H19N3O4/c1-2-21-13-5-3-4-6-15(13)25-16-8-7-11(9-14(16)21)20-17(22)10-12(19)18(23)24/h3-9,12H,2,10,19H2,1H3,(H,20,22)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50561803 (CHEMBL4790691) Show SMILES OC(=O)C(F)(F)F.Cc1ccc(cc1)S(=O)(=O)n1cc(-c2ccc(cc2)C(F)(F)F)c2ccc(CO[C@@H]([C@H](N)C(O)=O)C(O)=O)cc12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	309	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00342 BindingDB Entry DOI: 10.7270/Q2WH2TQZ
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50561803 (CHEMBL4790691) Show SMILES OC(=O)C(F)(F)F.Cc1ccc(cc1)S(=O)(=O)n1cc(-c2ccc(cc2)C(F)(F)F)c2ccc(CO[C@@H]([C@H](N)C(O)=O)C(O)=O)cc12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00342 BindingDB Entry DOI: 10.7270/Q2WH2TQZ
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410458 (CHEMBL2113123) Show SMILES Cc1cc(ccc1NC(=O)C[C@H](N)C(O)=O)-c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C18H17F3N2O3/c1-10-7-12(11-3-2-4-13(8-11)18(19,20)21)5-6-15(10)23-16(24)9-14(22)17(25)26/h2-8,14H,9,22H2,1H3,(H,23,24)(H,25,26)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366637 (CHEMBL4164207) Show SMILES N[C@@H]([C@H](OCC1CCCCC1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H19NO5/c12-8(10(13)14)9(11(15)16)17-6-7-4-2-1-3-5-7/h7-9H,1-6,12H2,(H,13,14)(H,15,16)/t8-,9-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366637 (CHEMBL4164207) Show SMILES N[C@@H]([C@H](OCC1CCCCC1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H19NO5/c12-8(10(13)14)9(11(15)16)17-6-7-4-2-1-3-5-7/h7-9H,1-6,12H2,(H,13,14)(H,15,16)/t8-,9-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50197046 (CHEMBL3939524) Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C16H16N2O6S/c17-13(15(19)20)14(16(21)22)18-25(23,24)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13-14,18H,17H2,(H,19,20)(H,21,22)/t13-,14?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method				J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50173914 (2-Amino-N-(3'-chloro-4'-fluoro-6-methyl-biphenyl-3...) Show SMILES Cc1ccc(NC(=O)CC(N)C(O)=O)cc1-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C17H16ClFN2O3/c1-9-2-4-11(21-16(22)8-15(20)17(23)24)7-12(9)10-3-5-14(19)13(18)6-10/h2-7,15H,8,20H2,1H3,(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410448 (CHEMBL2113120) Show SMILES N[C@@H](CC(=O)Nc1ccc2oc3cc(F)c(F)cc3c2c1)C(O)=O |r| Show InChI InChI=1S/C16H12F2N2O4/c17-10-4-9-8-3-7(20-15(21)6-12(19)16(22)23)1-2-13(8)24-14(9)5-11(10)18/h1-5,12H,6,19H2,(H,20,21)(H,22,23)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50197046 (CHEMBL3939524) Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C16H16N2O6S/c17-13(15(19)20)14(16(21)22)18-25(23,24)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13-14,18H,17H2,(H,19,20)(H,21,22)/t13-,14?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method				J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50410464 (CHEMBL2113111) Show SMILES CCc1cc(ccc1NC(=O)C[C@H](N)C(O)=O)-c1ccc(F)c(Cl)c1 |r| Show InChI InChI=1S/C18H18ClFN2O3/c1-2-10-7-11(12-3-5-14(20)13(19)8-12)4-6-16(10)22-17(23)9-15(21)18(24)25/h3-8,15H,2,9,21H2,1H3,(H,22,23)(H,24,25)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2				Bioorg Med Chem Lett 15: 4985-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.003 BindingDB Entry DOI: 10.7270/Q25H7FSP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366651 (CHEMBL4173825) Show SMILES N[C@@H]([C@H](OCC1CCC1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C9H15NO5/c10-6(8(11)12)7(9(13)14)15-4-5-2-1-3-5/h5-7H,1-4,10H2,(H,11,12)(H,13,14)/t6-,7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366651 (CHEMBL4173825) Show SMILES N[C@@H]([C@H](OCC1CCC1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C9H15NO5/c10-6(8(11)12)7(9(13)14)15-4-5-2-1-3-5/h5-7H,1-4,10H2,(H,11,12)(H,13,14)/t6-,7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	692	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
					More data for this Ligand-Target Pair

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