Found 100 hits of ki for UniProtKB: P54829 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103445
(CHEMBL3398243)Show InChI InChI=1S/C7H3F3S5/c8-7(9,10)4-1-2-5-6(3-4)12-14-15-13-11-5/h1-3H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 109 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250606
(CHEMBL4077342)Show SMILES OP(O)(=O)C(F)(c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C24H21Cl3F2NO6PS/c25-20-14-22(27)21(26)13-17(20)12-16-2-1-3-19(23(16)28)15-4-6-18(7-5-15)24(29,37(31,32)33)38(34,35)30-8-10-36-11-9-30/h1-7,13-14H,8-12H2,(H2,31,32,33) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of STEP (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112131 BindingDB Entry DOI: 10.7270/Q21C21KH |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50067512
(CHEMBL3401893)Show InChI InChI=1S/C7H4F3NS5/c8-7(9,10)3-1-4(11)6-5(2-3)12-14-16-15-13-6/h1-2H,11H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103444
(CHEMBL3398244)Show InChI InChI=1S/C7H7NS5.ClH/c1-4-2-5(8)7-6(3-4)9-11-13-12-10-7;/h2-3H,8H2,1H3;1H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103448
(CHEMBL3398247)Show InChI InChI=1S/C9H6F3NOS5/c1-4(14)13-6-2-5(9(10,11)12)3-7-8(6)16-18-19-17-15-7/h2-3H,1H3,(H,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 123 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103447
(CHEMBL3398250)Show SMILES Cl.Cl.Nc1cc(cc2SSSc3c(N)cc(cc3SSSc12)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H8F6N2S6.2ClH/c15-13(16,17)5-1-7(21)11-9(3-5)23-28-26-12-8(22)2-6(14(18,19)20)4-10(12)24-27-25-11;;/h1-4H,21-22H2;2*1H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103450
(CHEMBL3398249)Show InChI InChI=1S/C14H10F3NS5/c15-14(16,17)10-6-11(18-8-9-4-2-1-3-5-9)13-12(7-10)19-21-23-22-20-13/h1-7,18H,8H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 175 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103443
(CHEMBL3398245)Show InChI InChI=1S/C6H5NS5.ClH/c7-4-2-1-3-5-6(4)9-11-12-10-8-5;/h1-3H,7H2;1H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 183 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103446
(CHEMBL3398251)Show InChI InChI=1S/C7H2F3NO2S3/c8-7(9,10)3-1-4(11(12)13)6-5(2-3)14-16-15-6/h1-2H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50103449
(CHEMBL3398248)Show InChI InChI=1S/C9H8F3NS5/c1-2-13-6-3-5(9(10,11)12)4-7-8(6)15-17-18-16-14-7/h3-4,13H,2H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50067504
(CHEMBL3398246)Show InChI InChI=1S/C9H3F6NOS5/c10-8(11,12)3-1-4(16-7(17)9(13,14)15)6-5(2-3)18-20-22-21-19-6/h1-2H,(H,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 235 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assay |
Bioorg Med Chem Lett 25: 1044-6 (2015)
Article DOI: 10.1016/j.bmcl.2015.01.020 BindingDB Entry DOI: 10.7270/Q2QN68JF |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583252
(CHEMBL5077745)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250610
(CHEMBL4076072)Show SMILES OP(O)(=O)C(c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C24H22Cl3FNO6PS/c25-20-14-22(27)21(26)13-18(20)12-17-2-1-3-19(23(17)28)15-4-6-16(7-5-15)24(36(30,31)32)37(33,34)29-8-10-35-11-9-29/h1-7,13-14,24H,8-12H2,(H2,30,31,32) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250608
(CHEMBL4092589)Show SMILES OP(O)(=O)C(F)(C(=O)c1ccccc1)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F Show InChI InChI=1S/C27H18Cl3F2O4P/c28-22-15-24(30)23(29)14-19(22)13-18-7-4-8-21(25(18)31)16-9-11-20(12-10-16)27(32,37(34,35)36)26(33)17-5-2-1-3-6-17/h1-12,14-15H,13H2,(H2,34,35,36) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583253
(CHEMBL5083897)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 920 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250601
(CHEMBL4070970)Show SMILES OP(O)(=O)C(F)(C(=O)C1CCCCC1)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F Show InChI InChI=1S/C27H24Cl3F2O4P/c28-22-15-24(30)23(29)14-19(22)13-18-7-4-8-21(25(18)31)16-9-11-20(12-10-16)27(32,37(34,35)36)26(33)17-5-2-1-3-6-17/h4,7-12,14-15,17H,1-3,5-6,13H2,(H2,34,35,36) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583244
(CHEMBL5072214)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)COCCOCCN)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250600
(CHEMBL4103050)Show SMILES OP(O)(=O)C(F)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F Show InChI InChI=1S/C20H14Cl3F2O3P/c21-16-10-18(23)17(22)9-14(16)8-13-2-1-3-15(19(13)24)11-4-6-12(7-5-11)20(25)29(26,27)28/h1-7,9-10,20H,8H2,(H2,26,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250603
(CHEMBL4102693)Show SMILES OP(O)(=O)C(C(=O)N1CCOCC1)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F Show InChI InChI=1S/C25H22Cl3FNO5P/c26-20-14-22(28)21(27)13-18(20)12-17-2-1-3-19(23(17)29)15-4-6-16(7-5-15)24(36(32,33)34)25(31)30-8-10-35-11-9-30/h1-7,13-14,24H,8-12H2,(H2,32,33,34) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583233
(CHEMBL5085890)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583249
(CHEMBL5071305)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CN)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583250
(CHEMBL5080018)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50564155
(CHEMBL4792956)Show SMILES [#6]-c1cc(ccc1-c1ccc(\[#6]=[#6]-2\[#6](=O)-c3ccccc3-[#6]-2=O)o1)-[#6](-[#8])=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Competitive inhibition of N-terminal His-tagged striatal-enriched protein tyrosine phosphatase (unknown origin) assessed as inhibition of p-nitrophen... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112131 BindingDB Entry DOI: 10.7270/Q21C21KH |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50564156
(CHEMBL4780469)Show SMILES OC(=O)c1cccc2C3C(Cl)C(CC3C(Nc12)c1ccc(F)cc1)Sc1ccccc1[N+]([O-])=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Competitive inhibition of N-terminal His-tagged striatal-enriched protein tyrosine phosphatase (unknown origin) assessed as inhibition of p-nitrophen... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112131 BindingDB Entry DOI: 10.7270/Q21C21KH |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250604
(CHEMBL4084768)Show SMILES CN(C)C(=O)C(c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F)P(O)(O)=O Show InChI InChI=1S/C23H20Cl3FNO4P/c1-28(2)23(29)22(33(30,31)32)14-8-6-13(7-9-14)17-5-3-4-15(21(17)27)10-16-11-19(25)20(26)12-18(16)24/h3-9,11-12,22H,10H2,1-2H3,(H2,30,31,32) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250607
(CHEMBL4069436)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F Show InChI InChI=1S/C20H13Cl3F3O3P/c21-16-10-18(23)17(22)9-13(16)8-12-2-1-3-15(19(12)24)11-4-6-14(7-5-11)20(25,26)30(27,28)29/h1-7,9-10H,8H2,(H2,27,28,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583251
(CHEMBL5074161)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583237
(CHEMBL5083791)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583235
(CHEMBL5078422)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250599
(CHEMBL4088863)Show SMILES O[C@H](c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F)P(O)(O)=O |r| Show InChI InChI=1S/C20H15Cl3FO4P/c21-16-10-18(23)17(22)9-14(16)8-13-2-1-3-15(19(13)24)11-4-6-12(7-5-11)20(25)29(26,27)28/h1-7,9-10,20,25H,8H2,(H2,26,27,28)/t20-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250609
(CHEMBL4105477)Show SMILES OP(O)(=O)C(C(=O)N1CCCCC1)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F Show InChI InChI=1S/C26H24Cl3FNO4P/c27-21-15-23(29)22(28)14-19(21)13-18-5-4-6-20(24(18)30)16-7-9-17(10-8-16)25(36(33,34)35)26(32)31-11-2-1-3-12-31/h4-10,14-15,25H,1-3,11-13H2,(H2,33,34,35) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583239
(CHEMBL5088751)Show SMILES CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250602
(CHEMBL4087599)Show SMILES OP(O)(=O)C(F)(C(=O)N1CCCCC1)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F Show InChI InChI=1S/C26H23Cl3F2NO4P/c27-21-15-23(29)22(28)14-18(21)13-17-5-4-6-20(24(17)30)16-7-9-19(10-8-16)26(31,37(34,35)36)25(33)32-11-2-1-3-12-32/h4-10,14-15H,1-3,11-13H2,(H2,34,35,36) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583241
(CHEMBL5086743)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](C)C(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583232
(CHEMBL5083288)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250597
(CHEMBL4096664)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Br)c1 Show InChI InChI=1S/C20H14BrCl2F2O3P/c21-17-11-19(23)18(22)10-15(17)9-12-2-1-3-14(8-12)13-4-6-16(7-5-13)20(24,25)29(26,27)28/h1-8,10-11H,9H2,(H2,26,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50564157
(CHEMBL4792963)Show SMILES OC(=O)c1cc(ccc1O)-c1ccc(\C=C2/Sc3ccccc3C2=O)o1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Competitive inhibition of N-terminal His-tagged striatal-enriched protein tyrosine phosphatase (unknown origin) assessed as inhibition of p-nitrophen... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112131 BindingDB Entry DOI: 10.7270/Q21C21KH |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250606
(CHEMBL4077342)Show SMILES OP(O)(=O)C(F)(c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C24H21Cl3F2NO6PS/c25-20-14-22(27)21(26)13-17(20)12-16-2-1-3-19(23(16)28)15-4-6-18(7-5-15)24(29,37(31,32)33)38(34,35)30-8-10-36-11-9-30/h1-7,13-14H,8-12H2,(H2,31,32,33) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250606
(CHEMBL4077342)Show SMILES OP(O)(=O)C(F)(c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C24H21Cl3F2NO6PS/c25-20-14-22(27)21(26)13-17(20)12-16-2-1-3-19(23(16)28)15-4-6-18(7-5-15)24(29,37(31,32)33)38(34,35)30-8-10-36-11-9-30/h1-7,13-14H,8-12H2,(H2,31,32,33) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583236
(CHEMBL5088998)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250596
(CHEMBL4073186)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1 Show InChI InChI=1S/C20H14Cl3F2O3P/c21-17-11-19(23)18(22)10-15(17)9-12-2-1-3-14(8-12)13-4-6-16(7-5-13)20(24,25)29(26,27)28/h1-8,10-11H,9H2,(H2,26,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583238
(CHEMBL5082530)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583248
(CHEMBL5089288)Show SMILES NCCOCCOCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583234
(CHEMBL5091352)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50564158
(CHEMBL4794022)Show SMILES OC(=O)c1cccc2C3C(Cl)C(CC3C(Nc12)c1cccc(Br)c1)Sc1ccccc1[N+]([O-])=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Competitive inhibition of N-terminal His-tagged striatal-enriched protein tyrosine phosphatase (unknown origin) assessed as inhibition of p-nitrophen... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112131 BindingDB Entry DOI: 10.7270/Q21C21KH |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583242
(CHEMBL5091465)Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)COCCOCCN)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250595
(CHEMBL4100037)Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2F)c1 Show InChI InChI=1S/C20H14Cl2F3O3P/c21-17-10-15(19(23)11-18(17)22)9-12-2-1-3-14(8-12)13-4-6-16(7-5-13)20(24,25)29(26,27)28/h1-8,10-11H,9H2,(H2,26,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583246
(CHEMBL5086289)Show SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)COCCOCCN)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50583240
(CHEMBL5081376)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(O)=O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 6.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of TAM-3Y-F2Pmp peptide binding to N-terminal His6-fused STEP32 (282 to 563 residues) (unknown origin) expressed in Escherichia coli BL21(... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01303 BindingDB Entry DOI: 10.7270/Q24J0K1V |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 5
(Homo sapiens (Human)) | BDBM50250605
(CHEMBL4075995)Show SMILES CNC(=O)C(c1ccc(cc1)-c1cccc(Cc2cc(Cl)c(Cl)cc2Cl)c1F)P(O)(O)=O Show InChI InChI=1S/C22H18Cl3FNO4P/c1-27-22(28)21(32(29,30)31)13-7-5-12(6-8-13)16-4-2-3-14(20(16)26)9-15-10-18(24)19(25)11-17(15)23/h2-8,10-11,21H,9H2,1H3,(H,27,28)(H2,29,30,31) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90... |
J Med Chem 60: 9299-9319 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01292 BindingDB Entry DOI: 10.7270/Q2NZ8B27 |
More data for this Ligand-Target Pair | |