Found 82 hits of ec50 data for polymerid = 50000096 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50403050
(CHEMBL2216803)Show SMILES COc1ccc(CCNC(=O)C[C@H]2S[C@H](N(C2=O)c2ccc(C(N)=O)c(Cl)c2)c2ccc(cc2)C#Cc2ccccc2)cc1OC |r| Show InChI InChI=1S/C36H32ClN3O5S/c1-44-30-17-12-25(20-31(30)45-2)18-19-39-33(41)22-32-35(43)40(27-15-16-28(34(38)42)29(37)21-27)36(46-32)26-13-10-24(11-14-26)9-8-23-6-4-3-5-7-23/h3-7,10-17,20-21,32,36H,18-19,22H2,1-2H3,(H2,38,42)(H,39,41)/t32-,36+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Dr. Hari Singh Gour University
Curated by ChEMBL
| Assay Description
Allosteric activation of human FSH receptor |
Bioorg Med Chem 20: 3378-95 (2012)
Article DOI: 10.1016/j.bmc.2012.03.069
BindingDB Entry DOI: 10.7270/Q2222VX4 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142662
(1-Butyl-1-[4'-((2S,5S)-1,5-dimethyl-4-octyl-3,6-di...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)NC)c2)C1=O Show InChI InChI=1S/C34H50N4O3/c1-6-8-10-11-12-13-22-38-26(3)32(39)36(5)31(33(38)40)24-27-17-19-29(20-18-27)30-16-14-15-28(23-30)25-37(21-9-7-2)34(41)35-4/h14-20,23,26,31H,6-13,21-22,24-25H2,1-5H3,(H,35,41)/t26-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity of the compound was determined in CHO-hFSHR cell-based cAMP accumulation assay |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142654
(2-{(S)-3-[3'-(1-Butyl-3-methyl-ureidomethyl)-biphe...)Show SMILES CCCCCNC(=O)CN1CC(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)NC)c2)C1=O Show InChI InChI=1S/C32H45N5O4/c1-5-7-9-17-34-29(38)22-37-23-30(39)35(4)28(31(37)40)20-24-13-15-26(16-14-24)27-12-10-11-25(19-27)21-36(18-8-6-2)32(41)33-3/h10-16,19,28H,5-9,17-18,20-23H2,1-4H3,(H,33,41)(H,34,38)/t28-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142669
(CHEMBL47953 | [4'-((2S,5S)-1,5-Dimethyl-4-octyl-3,...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(COC)C(=O)OC)c2)C1=O Show InChI InChI=1S/C32H45N3O5/c1-6-7-8-9-10-11-19-35-24(2)30(36)33(3)29(31(35)37)21-25-15-17-27(18-16-25)28-14-12-13-26(20-28)22-34(23-39-4)32(38)40-5/h12-18,20,24,29H,6-11,19,21-23H2,1-5H3/t24-,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142672
(Butyl-[4'-((2S,5S)-1,5-dimethyl-4-octyl-3,6-dioxo-...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)OC)c2)C1=O Show InChI InChI=1S/C34H49N3O4/c1-6-8-10-11-12-13-22-37-26(3)32(38)35(4)31(33(37)39)24-27-17-19-29(20-18-27)30-16-14-15-28(23-30)25-36(21-9-7-2)34(40)41-5/h14-20,23,26,31H,6-13,21-22,24-25H2,1-5H3/t26-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142651
(CHEMBL300022 | N-Hexyl-2-[(S)-4-methyl-2,5-dioxo-3...)Show SMILES CCCCCCNC(=O)CN1CC(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C29H39N3O6/c1-6-7-8-9-14-30-26(33)18-32-19-27(34)31(2)23(29(32)35)15-20-10-12-21(13-11-20)22-16-24(36-3)28(38-5)25(17-22)37-4/h10-13,16-17,23H,6-9,14-15,18-19H2,1-5H3,(H,30,33)/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142670
(1-[4'-((2S,5S)-1,5-Dimethyl-4-octyl-3,6-dioxo-pipe...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(COC)C(=O)NC)c2)C1=O Show InChI InChI=1S/C32H46N4O4/c1-6-7-8-9-10-11-19-36-24(2)30(37)34(4)29(31(36)38)21-25-15-17-27(18-16-25)28-14-12-13-26(20-28)22-35(23-40-5)32(39)33-3/h12-18,20,24,29H,6-11,19,21-23H2,1-5H3,(H,33,39)/t24-,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142675
(1-Butyl-1-[4'-((2S,5S)-4-hexyl-1,5-dimethyl-3,6-di...)Show SMILES CCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)NC)c2)C1=O Show InChI InChI=1S/C32H46N4O3/c1-6-8-10-11-20-36-24(3)30(37)34(5)29(31(36)38)22-25-15-17-27(18-16-25)28-14-12-13-26(21-28)23-35(19-9-7-2)32(39)33-4/h12-18,21,24,29H,6-11,19-20,22-23H2,1-5H3,(H,33,39)/t24-,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142662
(1-Butyl-1-[4'-((2S,5S)-1,5-dimethyl-4-octyl-3,6-di...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)NC)c2)C1=O Show InChI InChI=1S/C34H50N4O3/c1-6-8-10-11-12-13-22-38-26(3)32(39)36(5)31(33(38)40)24-27-17-19-29(20-18-27)30-16-14-15-28(23-30)25-37(21-9-7-2)34(41)35-4/h14-20,23,26,31H,6-13,21-22,24-25H2,1-5H3,(H,35,41)/t26-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity of the compound was determined in CHO-hFSHR cell-based cAMP accumulation assay |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142656
(Butyl-[4'-((2S,5S)-4-hexyl-1,5-dimethyl-3,6-dioxo-...)Show SMILES CCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)OC)c2)C1=O Show InChI InChI=1S/C32H45N3O4/c1-6-8-10-11-20-35-24(3)30(36)33(4)29(31(35)37)22-25-15-17-27(18-16-25)28-14-12-13-26(21-28)23-34(19-9-7-2)32(38)39-5/h12-18,21,24,29H,6-11,19-20,22-23H2,1-5H3/t24-,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142675
(1-Butyl-1-[4'-((2S,5S)-4-hexyl-1,5-dimethyl-3,6-di...)Show SMILES CCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)NC)c2)C1=O Show InChI InChI=1S/C32H46N4O3/c1-6-8-10-11-20-36-24(3)30(37)34(5)29(31(36)38)22-25-15-17-27(18-16-25)28-14-12-13-26(21-28)23-35(19-9-7-2)32(39)33-4/h12-18,21,24,29H,6-11,19-20,22-23H2,1-5H3,(H,33,39)/t24-,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity of the compound was determined in CHO-hFSHR cell-based cAMP accumulation assay |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142680
(CHEMBL46216 | N-[4'-((2S,5S)-1,5-Dimethyl-4-octyl-...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(COC)C(C)=O)c2)C1=O Show InChI InChI=1S/C32H45N3O4/c1-6-7-8-9-10-11-19-35-24(2)31(37)33(4)30(32(35)38)21-26-15-17-28(18-16-26)29-14-12-13-27(20-29)22-34(23-39-5)25(3)36/h12-18,20,24,30H,6-11,19,21-23H2,1-5H3/t24-,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142676
((3S,6S)-1,3-Dimethyl-4-octyl-6-(3',4',5'-trimethox...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C30H42N2O5/c1-7-8-9-10-11-12-17-32-21(2)29(33)31(3)25(30(32)34)18-22-13-15-23(16-14-22)24-19-26(35-4)28(37-6)27(20-24)36-5/h13-16,19-21,25H,7-12,17-18H2,1-6H3/t21-,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142661
(CHEMBL47059 | N-Butyl-N-[4'-((2S,5S)-1,5-dimethyl-...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(C)=O)c2)C1=O Show InChI InChI=1S/C34H49N3O3/c1-6-8-10-11-12-13-22-37-26(3)33(39)35(5)32(34(37)40)24-28-17-19-30(20-18-28)31-16-14-15-29(23-31)25-36(27(4)38)21-9-7-2/h14-20,23,26,32H,6-13,21-22,24-25H2,1-5H3/t26-,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142657
((3S,6S)-1-Heptyl-4,6-dimethyl-3-(3',4',5'-trimetho...)Show SMILES CCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C29H40N2O5/c1-7-8-9-10-11-16-31-20(2)28(32)30(3)24(29(31)33)17-21-12-14-22(15-13-21)23-18-25(34-4)27(36-6)26(19-23)35-5/h12-15,18-20,24H,7-11,16-17H2,1-6H3/t20-,24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142672
(Butyl-[4'-((2S,5S)-1,5-dimethyl-4-octyl-3,6-dioxo-...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)OC)c2)C1=O Show InChI InChI=1S/C34H49N3O4/c1-6-8-10-11-12-13-22-37-26(3)32(38)35(4)31(33(37)39)24-27-17-19-29(20-18-27)30-16-14-15-28(23-30)25-36(21-9-7-2)34(40)41-5/h14-20,23,26,31H,6-13,21-22,24-25H2,1-5H3/t26-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity of the compound was determined in CHO-hFSHR cell-based cAMP accumulation assay |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142657
((3S,6S)-1-Heptyl-4,6-dimethyl-3-(3',4',5'-trimetho...)Show SMILES CCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C29H40N2O5/c1-7-8-9-10-11-16-31-20(2)28(32)30(3)24(29(31)33)17-21-12-14-22(15-13-21)23-18-25(34-4)27(36-6)26(19-23)35-5/h12-15,18-20,24H,7-11,16-17H2,1-6H3/t20-,24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142676
((3S,6S)-1,3-Dimethyl-4-octyl-6-(3',4',5'-trimethox...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C30H42N2O5/c1-7-8-9-10-11-12-17-32-21(2)29(33)31(3)25(30(32)34)18-22-13-15-23(16-14-22)24-19-26(35-4)28(37-6)27(20-24)36-5/h13-16,19-21,25H,7-12,17-18H2,1-6H3/t21-,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity of the compound was determined in CHO-hFollicle stimulating hormone receptor cell-based cAMP accumulation assay |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142661
(CHEMBL47059 | N-Butyl-N-[4'-((2S,5S)-1,5-dimethyl-...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(C)=O)c2)C1=O Show InChI InChI=1S/C34H49N3O3/c1-6-8-10-11-12-13-22-37-26(3)33(39)35(5)32(34(37)40)24-28-17-19-30(20-18-28)31-16-14-15-29(23-31)25-36(27(4)38)21-9-7-2/h14-20,23,26,32H,6-13,21-22,24-25H2,1-5H3/t26-,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity of the compound was determined in CHO-hFSHR cell-based cAMP accumulation assay |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142656
(Butyl-[4'-((2S,5S)-4-hexyl-1,5-dimethyl-3,6-dioxo-...)Show SMILES CCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)OC)c2)C1=O Show InChI InChI=1S/C32H45N3O4/c1-6-8-10-11-20-35-24(3)30(36)33(4)29(31(35)37)22-25-15-17-27(18-16-25)28-14-12-13-26(21-28)23-34(19-9-7-2)32(38)39-5/h12-18,21,24,29H,6-11,19-20,22-23H2,1-5H3/t24-,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 48 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142656
(Butyl-[4'-((2S,5S)-4-hexyl-1,5-dimethyl-3,6-dioxo-...)Show SMILES CCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)OC)c2)C1=O Show InChI InChI=1S/C32H45N3O4/c1-6-8-10-11-20-35-24(3)30(36)33(4)29(31(35)37)22-25-15-17-27(18-16-25)28-14-12-13-26(21-28)23-34(19-9-7-2)32(38)39-5/h12-18,21,24,29H,6-11,19-20,22-23H2,1-5H3/t24-,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 48 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity of the compound was determined in CHO-hFSHR cell-based cAMP accumulation assay |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50403051
(CHEMBL2216804)Show SMILES CCOc1cc(CCNC(=O)C[C@H]2S[C@H](NC2=O)c2ccc(cc2)C#Cc2ccccc2)ccc1OC |r| Show InChI InChI=1S/C30H30N2O4S/c1-3-36-26-19-23(13-16-25(26)35-2)17-18-31-28(33)20-27-29(34)32-30(37-27)24-14-11-22(12-15-24)10-9-21-7-5-4-6-8-21/h4-8,11-16,19,27,30H,3,17-18,20H2,1-2H3,(H,31,33)(H,32,34)/t27-,30+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
Dr. Hari Singh Gour University
Curated by ChEMBL
| Assay Description
Agonist activity at human FSH receptor by aromatase-based assay |
Bioorg Med Chem 20: 3378-95 (2012)
Article DOI: 10.1016/j.bmc.2012.03.069
BindingDB Entry DOI: 10.7270/Q2222VX4 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142674
((3S,6R)-1,3-Dimethyl-4-octyl-6-(3',4',5'-trimethox...)Show SMILES CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C30H42N2O5/c1-7-8-9-10-11-12-17-32-21(2)29(33)31(3)25(30(32)34)18-22-13-15-23(16-14-22)24-19-26(35-4)28(37-6)27(20-24)36-5/h13-16,19-21,25H,7-12,17-18H2,1-6H3/t21-,25+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 68 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50403051
(CHEMBL2216804)Show SMILES CCOc1cc(CCNC(=O)C[C@H]2S[C@H](NC2=O)c2ccc(cc2)C#Cc2ccccc2)ccc1OC |r| Show InChI InChI=1S/C30H30N2O4S/c1-3-36-26-19-23(13-16-25(26)35-2)17-18-31-28(33)20-27-29(34)32-30(37-27)24-14-11-22(12-15-24)10-9-21-7-5-4-6-8-21/h4-8,11-16,19,27,30H,3,17-18,20H2,1-2H3,(H,31,33)(H,32,34)/t27-,30+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 80 | n/a | n/a | n/a | n/a |
Dr. Hari Singh Gour University
Curated by ChEMBL
| Assay Description
Agonist activity at human FSH receptor by cAMP-based assay |
Bioorg Med Chem 20: 3378-95 (2012)
Article DOI: 10.1016/j.bmc.2012.03.069
BindingDB Entry DOI: 10.7270/Q2222VX4 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50012105
(CHEMBL3263667)Show SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1coc(n1)C1CC1)C(=O)NCCCN1CCCC1=O Show InChI InChI=1S/C32H38N6O4/c1-22-6-2-3-7-27(22)36-16-18-37(19-17-36)28-12-11-24(30(40)33-13-5-15-38-14-4-8-29(38)39)20-25(28)34-31(41)26-21-42-32(35-26)23-9-10-23/h2-3,6-7,11-12,20-21,23H,4-5,8-10,13-19H2,1H3,(H,33,40)(H,34,41) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a... |
ACS Med Chem Lett 7: 345-7 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00082
BindingDB Entry DOI: 10.7270/Q2HQ41T6 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50012120
(CHEMBL3263691)Show SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1coc(n1)C1CC1)C(=O)NCCCc1nn[nH]n1 Show InChI InChI=1S/C29H33N9O3/c1-19-5-2-3-6-24(19)37-13-15-38(16-14-37)25-11-10-21(27(39)30-12-4-7-26-33-35-36-34-26)17-22(25)31-28(40)23-18-41-29(32-23)20-8-9-20/h2-3,5-6,10-11,17-18,20H,4,7-9,12-16H2,1H3,(H,30,39)(H,31,40)(H,33,34,35,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a... |
ACS Med Chem Lett 7: 345-7 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00082
BindingDB Entry DOI: 10.7270/Q2HQ41T6 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50173579
(CHEMBL3809148)Show SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)cc1)C(=O)NCCCN1CCCC1=O Show InChI InChI=1S/C32H36FN5O3/c1-23-6-2-3-7-28(23)36-18-20-37(21-19-36)29-14-11-25(31(40)34-15-5-17-38-16-4-8-30(38)39)22-27(29)35-32(41)24-9-12-26(33)13-10-24/h2-3,6-7,9-14,22H,4-5,8,15-21H2,1H3,(H,34,40)(H,35,41) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a... |
ACS Med Chem Lett 7: 345-7 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00082
BindingDB Entry DOI: 10.7270/Q2HQ41T6 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50173578
(CHEMBL3263694)Show SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1ccco1)C(=O)NCCCN1CCCC1=O Show InChI InChI=1S/C30H35N5O4/c1-22-7-2-3-8-25(22)33-16-18-34(19-17-33)26-12-11-23(21-24(26)32-30(38)27-9-5-20-39-27)29(37)31-13-6-15-35-14-4-10-28(35)36/h2-3,5,7-9,11-12,20-21H,4,6,10,13-19H2,1H3,(H,31,37)(H,32,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a... |
ACS Med Chem Lett 7: 345-7 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00082
BindingDB Entry DOI: 10.7270/Q2HQ41T6 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50173580
(CHEMBL3808949)Show SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1ccco1)C(=O)NCCCNC(=O)NCC=C Show InChI InChI=1S/C30H36N6O4/c1-3-13-32-30(39)33-15-7-14-31-28(37)23-11-12-26(24(21-23)34-29(38)27-10-6-20-40-27)36-18-16-35(17-19-36)25-9-5-4-8-22(25)2/h3-6,8-12,20-21H,1,7,13-19H2,2H3,(H,31,37)(H,34,38)(H2,32,33,39) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a... |
ACS Med Chem Lett 7: 345-7 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00082
BindingDB Entry DOI: 10.7270/Q2HQ41T6 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50012120
(CHEMBL3263691)Show SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1coc(n1)C1CC1)C(=O)NCCCc1nn[nH]n1 Show InChI InChI=1S/C29H33N9O3/c1-19-5-2-3-6-24(19)37-13-15-38(16-14-37)25-11-10-21(27(39)30-12-4-7-26-33-35-36-34-26)17-22(25)31-28(40)23-18-41-29(32-23)20-8-9-20/h2-3,5-6,10-11,17-18,20H,4,7-9,12-16H2,1H3,(H,30,39)(H,31,40)(H,33,34,35,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human FSHR expressed in rat granulocytes assessed as FSH-induced estradiol production after 72 hrs by radioimmunoss... |
ACS Med Chem Lett 7: 345-7 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00082
BindingDB Entry DOI: 10.7270/Q2HQ41T6 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50173581
(CHEMBL3809644)Show SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1coc(n1)C1CC1)C(=O)N[C@H]1CCC[C@H](O)C1 |r| Show InChI InChI=1S/C31H37N5O4/c1-20-5-2-3-8-27(20)35-13-15-36(16-14-35)28-12-11-22(29(38)32-23-6-4-7-24(37)18-23)17-25(28)33-30(39)26-19-40-31(34-26)21-9-10-21/h2-3,5,8,11-12,17,19,21,23-24,37H,4,6-7,9-10,13-16,18H2,1H3,(H,32,38)(H,33,39)/t23-,24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a... |
ACS Med Chem Lett 7: 345-7 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00082
BindingDB Entry DOI: 10.7270/Q2HQ41T6 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50012105
(CHEMBL3263667)Show SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1coc(n1)C1CC1)C(=O)NCCCN1CCCC1=O Show InChI InChI=1S/C32H38N6O4/c1-22-6-2-3-7-27(22)36-16-18-37(19-17-36)28-12-11-24(30(40)33-13-5-15-38-14-4-8-29(38)39)20-25(28)34-31(41)26-21-42-32(35-26)23-9-10-23/h2-3,6-7,11-12,20-21,23H,4-5,8-10,13-19H2,1H3,(H,33,40)(H,34,41) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human FSHR expressed in rat granulocytes assessed as FSH-induced estradiol production after 72 hrs by radioimmunoss... |
ACS Med Chem Lett 7: 345-7 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00082
BindingDB Entry DOI: 10.7270/Q2HQ41T6 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142665
((3S,6S)-1-Hexyl-4,6-dimethyl-3-(3',4',5'-trimethox...)Show SMILES CCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C28H38N2O5/c1-7-8-9-10-15-30-19(2)27(31)29(3)23(28(30)32)16-20-11-13-21(14-12-20)22-17-24(33-4)26(35-6)25(18-22)34-5/h11-14,17-19,23H,7-10,15-16H2,1-6H3/t19-,23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50173579
(CHEMBL3809148)Show SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)cc1)C(=O)NCCCN1CCCC1=O Show InChI InChI=1S/C32H36FN5O3/c1-23-6-2-3-7-28(23)36-18-20-37(21-19-36)29-14-11-25(31(40)34-15-5-17-38-16-4-8-30(38)39)22-27(29)35-32(41)24-9-12-26(33)13-10-24/h2-3,6-7,9-14,22H,4-5,8,15-21H2,1H3,(H,34,40)(H,35,41) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human FSHR expressed in rat granulocytes assessed as FSH-induced estradiol production after 72 hrs by radioimmunoss... |
ACS Med Chem Lett 7: 345-7 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00082
BindingDB Entry DOI: 10.7270/Q2HQ41T6 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142673
((3R,6S)-1,3-Dimethyl-4-octyl-6-(3',4',5'-trimethox...)Show SMILES CCCCCCCCN1[C@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C30H42N2O5/c1-7-8-9-10-11-12-17-32-21(2)29(33)31(3)25(30(32)34)18-22-13-15-23(16-14-22)24-19-26(35-4)28(37-6)27(20-24)36-5/h13-16,19-21,25H,7-12,17-18H2,1-6H3/t21-,25+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50335467
(5-amino-N-tert-butyl-2-(methylthio)-4-(3-(2-oxo-2-...)Show SMILES CSc1nc(-c2cccc(NCC(=O)NCC#C)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C Show InChI InChI=1S/C23H26N6O2S2/c1-6-10-25-15(30)12-26-14-9-7-8-13(11-14)18-16-17(24)19(20(31)29-23(2,3)4)33-21(16)28-22(27-18)32-5/h1,7-9,11,26H,10,12,24H2,2-5H3,(H,25,30)(H,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter ge... |
ACS Med Chem Lett 2: 85-89 (2011)
Article DOI: 10.1021/ml100229v
BindingDB Entry DOI: 10.7270/Q2RV0NZG |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142678
(CHEMBL44663 | N-Butyl-N-[4'-((2S,5S)-4-hexyl-1,5-d...)Show SMILES CCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(C)=O)c2)C1=O Show InChI InChI=1S/C32H45N3O3/c1-6-8-10-11-20-35-24(3)31(37)33(5)30(32(35)38)22-26-15-17-28(18-16-26)29-14-12-13-27(21-29)23-34(25(4)36)19-9-7-2/h12-18,21,24,30H,6-11,19-20,22-23H2,1-5H3/t24-,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142653
(3'-(1-Butyl-3-methyl-ureidomethyl)-biphenyl-4-carb...)Show SMILES CCCCN(Cc1cccc(c1)-c1ccc(cc1)C(=O)NC1CCCCN(CC(=O)NCCc2ccc(Cl)cc2)C1=O)C(=O)NC Show InChI InChI=1S/C36H44ClN5O4/c1-3-4-21-42(36(46)38-2)24-27-8-7-9-30(23-27)28-13-15-29(16-14-28)34(44)40-32-10-5-6-22-41(35(32)45)25-33(43)39-20-19-26-11-17-31(37)18-12-26/h7-9,11-18,23,32H,3-6,10,19-22,24-25H2,1-2H3,(H,38,46)(H,39,43)(H,40,44) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against Follicle stimulating hormone receptor expressed in chinese hamster ovary cells(CHO) |
Bioorg Med Chem Lett 14: 1713-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.042
BindingDB Entry DOI: 10.7270/Q2V40TMR |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50335473
(5-amino-4-(3-(2-((1-(2-(2-(2-azidoethoxy)ethoxy)et...)Show SMILES CSc1nc(-c2cccc(NCC(=O)NCc3cn(CCOCCOCCN=[N+]=[N-])nn3)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C Show InChI InChI=1S/C29H38N12O4S2/c1-29(2,3)37-26(43)25-23(30)22-24(35-28(46-4)36-27(22)47-25)18-6-5-7-19(14-18)32-16-21(42)33-15-20-17-41(40-38-20)9-11-45-13-12-44-10-8-34-39-31/h5-7,14,17,32H,8-13,15-16,30H2,1-4H3,(H,33,42)(H,37,43) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 397 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter ge... |
ACS Med Chem Lett 2: 85-89 (2011)
Article DOI: 10.1021/ml100229v
BindingDB Entry DOI: 10.7270/Q2RV0NZG |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142681
((S)-4-Methyl-1-octyl-3-(3',4',5'-trimethoxy-biphen...)Show SMILES CCCCCCCCN1CC(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C29H40N2O5/c1-6-7-8-9-10-11-16-31-20-27(32)30(2)24(29(31)33)17-21-12-14-22(15-13-21)23-18-25(34-3)28(36-5)26(19-23)35-4/h12-15,18-19,24H,6-11,16-17,20H2,1-5H3/t24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142660
((S)-4-Methyl-1-nonyl-3-(3',4',5'-trimethoxy-biphen...)Show SMILES CCCCCCCCCN1CC(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C30H42N2O5/c1-6-7-8-9-10-11-12-17-32-21-28(33)31(2)25(30(32)34)18-22-13-15-23(16-14-22)24-19-26(35-3)29(37-5)27(20-24)36-4/h13-16,19-20,25H,6-12,17-18,21H2,1-5H3/t25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50173578
(CHEMBL3263694)Show SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1ccco1)C(=O)NCCCN1CCCC1=O Show InChI InChI=1S/C30H35N5O4/c1-22-7-2-3-8-25(22)33-16-18-34(19-17-33)26-12-11-23(21-24(26)32-30(38)27-9-5-20-39-27)29(37)31-13-6-15-35-14-4-10-28(35)36/h2-3,5,7-9,11-12,20-21H,4,6,10,13-19H2,1H3,(H,31,37)(H,32,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human FSHR expressed in rat granulocytes assessed as FSH-induced estradiol production after 72 hrs by radioimmunoss... |
ACS Med Chem Lett 7: 345-7 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00082
BindingDB Entry DOI: 10.7270/Q2HQ41T6 |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142658
((S)-3-(4'-Methoxy-3',5'-dimethyl-biphenyl-4-ylmeth...)Show SMILES CCCCCCCCN1CC(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(C)c(OC)c(C)c2)C1=O Show InChI InChI=1S/C29H40N2O3/c1-6-7-8-9-10-11-16-31-20-27(32)30(4)26(29(31)33)19-23-12-14-24(15-13-23)25-17-21(2)28(34-5)22(3)18-25/h12-15,17-18,26H,6-11,16,19-20H2,1-5H3/t26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142682
((3R,6R)-1,3-Dimethyl-4-octyl-6-(3',4',5'-trimethox...)Show SMILES CCCCCCCCN1[C@H](C)C(=O)N(C)[C@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C30H42N2O5/c1-7-8-9-10-11-12-17-32-21(2)29(33)31(3)25(30(32)34)18-22-13-15-23(16-14-22)24-19-26(35-4)28(37-6)27(20-24)36-5/h13-16,19-21,25H,7-12,17-18H2,1-6H3/t21-,25-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142654
(2-{(S)-3-[3'-(1-Butyl-3-methyl-ureidomethyl)-biphe...)Show SMILES CCCCCNC(=O)CN1CC(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(CCCC)C(=O)NC)c2)C1=O Show InChI InChI=1S/C32H45N5O4/c1-5-7-9-17-34-29(38)22-37-23-30(39)35(4)28(31(37)40)20-24-13-15-26(16-14-24)27-12-10-11-25(19-27)21-36(18-8-6-2)32(41)33-3/h10-16,19,28H,5-9,17-18,20-23H2,1-4H3,(H,33,41)(H,34,38)/t28-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against Follicle stimulating hormone receptor expressed in chinese hamster ovary cells(CHO) |
Bioorg Med Chem Lett 14: 1713-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.042
BindingDB Entry DOI: 10.7270/Q2V40TMR |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142666
((S)-1-Heptyl-4-methyl-3-(3',4',5'-trimethoxy-biphe...)Show SMILES CCCCCCCN1CC(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C28H38N2O5/c1-6-7-8-9-10-15-30-19-26(31)29(2)23(28(30)32)16-20-11-13-21(14-12-20)22-17-24(33-3)27(35-5)25(18-22)34-4/h11-14,17-18,23H,6-10,15-16,19H2,1-5H3/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142655
(2-{4-[4'-(1-Butyl-3-methyl-ureidomethyl)-biphenyl-...)Show SMILES CCCCCCNC(=O)Cn1c(O)c(Cc2ccc(cc2)-c2ccc(CN(CCCC)C(=O)NC)cc2)n(C)c1=O Show InChI InChI=1S/C32H45N5O4/c1-5-7-9-10-19-34-29(38)23-37-30(39)28(35(4)32(37)41)21-24-11-15-26(16-12-24)27-17-13-25(14-18-27)22-36(20-8-6-2)31(40)33-3/h11-18,39H,5-10,19-23H2,1-4H3,(H,33,40)(H,34,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against Follicle stimulating hormone receptor expressed in chinese hamster ovary cells(CHO) |
Bioorg Med Chem Lett 14: 1713-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.042
BindingDB Entry DOI: 10.7270/Q2V40TMR |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142668
((S)-1-Hexyl-4-methyl-3-(3',4',5'-trimethoxy-biphen...)Show SMILES CCCCCCN1CC(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C27H36N2O5/c1-6-7-8-9-14-29-18-25(30)28(2)22(27(29)31)15-19-10-12-20(13-11-19)21-16-23(32-3)26(34-5)24(17-21)33-4/h10-13,16-17,22H,6-9,14-15,18H2,1-5H3/t22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142651
(CHEMBL300022 | N-Hexyl-2-[(S)-4-methyl-2,5-dioxo-3...)Show SMILES CCCCCCNC(=O)CN1CC(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C29H39N3O6/c1-6-7-8-9-14-30-26(33)18-32-19-27(34)31(2)23(29(32)35)15-20-10-12-21(13-11-20)22-16-24(36-3)28(38-5)25(17-22)37-4/h10-13,16-17,23H,6-9,14-15,18-19H2,1-5H3,(H,30,33)/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against Follicle stimulating hormone receptor expressed in chinese hamster ovary cells(CHO) |
Bioorg Med Chem Lett 14: 1713-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.042
BindingDB Entry DOI: 10.7270/Q2V40TMR |
More data for this
Ligand-Target Pair | |
Follicle-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50142659
((S)-3-(3',4'-Dimethoxy-biphenyl-4-ylmethyl)-4-meth...)Show SMILES CCCCCCCCN1CC(=O)N(C)[C@@H](Cc2ccc(cc2)-c2ccc(OC)c(OC)c2)C1=O Show InChI InChI=1S/C28H38N2O4/c1-5-6-7-8-9-10-17-30-20-27(31)29(2)24(28(30)32)18-21-11-13-22(14-12-21)23-15-16-25(33-3)26(19-23)34-4/h11-16,19,24H,5-10,17-18,20H2,1-4H3/t24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a |
Pharmacopeia, Inc
Curated by ChEMBL
| Assay Description
Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay. |
Bioorg Med Chem Lett 14: 1717-20 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.043
BindingDB Entry DOI: 10.7270/Q2QC02XV |
More data for this
Ligand-Target Pair | |
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