BDBM50335467 5-amino-N-tert-butyl-2-(methylthio)-4-(3-(2-oxo-2-(prop-2-ynylamino)ethylamino)phenyl)thieno[2,3-d]pyrimidine-6-carboxamide::CHEMBL1651721
SMILES: CSc1nc(-c2cccc(NCC(=O)NCC#C)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C
InChI Key: InChIKey=OBTDWDIYUNCNGX-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Follicle stimulating hormone receptor (Homo sapiens (Human)) | BDBM50335467 (5-amino-N-tert-butyl-2-(methylthio)-4-(3-(2-oxo-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter ge... | ACS Med Chem Lett 2: 85-89 (2011) Article DOI: 10.1021/ml100229v BindingDB Entry DOI: 10.7270/Q2RV0NZG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human)) | BDBM50335467 (5-amino-N-tert-butyl-2-(methylthio)-4-(3-(2-oxo-2-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene... | ACS Med Chem Lett 2: 85-89 (2011) Article DOI: 10.1021/ml100229v BindingDB Entry DOI: 10.7270/Q2RV0NZG | |||||||||||
More data for this Ligand-Target Pair |