Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tubulin beta-3 chain (Homo sapiens) | BDBM50552403 (CHEMBL4800264) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115887 BindingDB Entry DOI: 10.7270/Q2HM5D3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115887 BindingDB Entry DOI: 10.7270/Q2HM5D3P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assay | J Med Chem 56: 6829-44 (2013) Article DOI: 10.1021/jm400639z BindingDB Entry DOI: 10.7270/Q2Z60S0W | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50001839 (CHEMBL428647 | PACLITAXEL | taxol) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115887 BindingDB Entry DOI: 10.7270/Q2HM5D3P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50001839 (CHEMBL428647 | PACLITAXEL | taxol) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assay | J Med Chem 56: 6829-44 (2013) Article DOI: 10.1021/jm400639z BindingDB Entry DOI: 10.7270/Q2Z60S0W | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50493263 (CHEMBL2425924) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assay | J Med Chem 56: 6829-44 (2013) Article DOI: 10.1021/jm400639z BindingDB Entry DOI: 10.7270/Q2Z60S0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50552407 (CHEMBL4758455) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115887 BindingDB Entry DOI: 10.7270/Q2HM5D3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50552402 (CHEMBL3040513) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115887 BindingDB Entry DOI: 10.7270/Q2HM5D3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50493264 (CHEMBL1824506) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assay | J Med Chem 56: 6829-44 (2013) Article DOI: 10.1021/jm400639z BindingDB Entry DOI: 10.7270/Q2Z60S0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50546440 (CHEMBL552462) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to beta tubulin in HEK293 cells assessed as disruption of microtubule polymerization by ITDRF-CETSA assay | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127453 BindingDB Entry DOI: 10.7270/Q21G0QVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50552406 (CHEMBL4763551) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115887 BindingDB Entry DOI: 10.7270/Q2HM5D3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50552404 (CHEMBL4751710) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115887 BindingDB Entry DOI: 10.7270/Q2HM5D3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50552405 (CHEMBL4791869) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by ... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115887 BindingDB Entry DOI: 10.7270/Q2HM5D3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta-3 chain (Homo sapiens) | BDBM50588315 (CHEMBL5197309) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmc.2021.116510 BindingDB Entry DOI: 10.7270/Q25M69NW | ||||||||||||
More data for this Ligand-Target Pair |