Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal transducer and activator of transcription 5B (Mus musculus) | BDBM50514414 (CHEMBL4439829) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille Curated by ChEMBL | Assay Description Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferation | J Med Chem 63: 3817-3833 (2020) Article DOI: 10.1021/acs.jmedchem.9b01183 BindingDB Entry DOI: 10.7270/Q2NZ8C0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 5B (Mus musculus) | BDBM50514413 (CHEMBL4555061) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille Curated by ChEMBL | Assay Description Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferation | J Med Chem 63: 3817-3833 (2020) Article DOI: 10.1021/acs.jmedchem.9b01183 BindingDB Entry DOI: 10.7270/Q2NZ8C0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 5B (Mus musculus) | BDBM50514407 (CHEMBL4483038) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.53E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille Curated by ChEMBL | Assay Description Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferation | J Med Chem 63: 3817-3833 (2020) Article DOI: 10.1021/acs.jmedchem.9b01183 BindingDB Entry DOI: 10.7270/Q2NZ8C0R | |||||||||||
More data for this Ligand-Target Pair |