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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: P42232   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Signal transducer and activator of transcription 5B


(Mus musculus)
BDBM50514414
PNG
(CHEMBL4439829)
Show SMILES COC(=O)c1nonc1NCn1cnnn1
Show InChI InChI=1S/C6H7N7O3/c1-15-6(14)4-5(10-16-9-4)7-2-13-3-8-11-12-13/h3H,2H2,1H3,(H,7,10)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Univ. Lille

Curated by ChEMBL


Assay Description
Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferation


J Med Chem 63: 3817-3833 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01183
BindingDB Entry DOI: 10.7270/Q2NZ8C0R
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 5B


(Mus musculus)
BDBM50514413
PNG
(CHEMBL4555061)
Show SMILES OC(=O)c1nonc1NCn1nnnc1Cc1ccccc1
Show InChI InChI=1S/C12H11N7O3/c20-12(21)10-11(16-22-15-10)13-7-19-9(14-17-18-19)6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,13,16)(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.60E+4n/an/an/an/an/an/a



Univ. Lille

Curated by ChEMBL


Assay Description
Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferation


J Med Chem 63: 3817-3833 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01183
BindingDB Entry DOI: 10.7270/Q2NZ8C0R
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 5B


(Mus musculus)
BDBM50514407
PNG
(CHEMBL4483038)
Show SMILES OC(=O)c1nonc1NCn1cnnn1
Show InChI InChI=1S/C5H5N7O3/c13-5(14)3-4(9-15-8-3)6-1-12-2-7-10-11-12/h2H,1H2,(H,6,9)(H,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.53E+5n/an/an/an/an/an/a



Univ. Lille

Curated by ChEMBL


Assay Description
Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferation


J Med Chem 63: 3817-3833 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01183
BindingDB Entry DOI: 10.7270/Q2NZ8C0R
More data for this
Ligand-Target Pair