Found 10 hits of kd for UniProtKB: P05369 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Farnesyl pyrophosphate synthase
(Rattus norvegicus) | BDBM50559034
(CHEMBL4785030)Show SMILES COc1ccccc1CN(CCS(=O)(=O)N1CCNCC1)S(=O)(=O)c1ccc(C)cc1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 1.43E+4 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111905
BindingDB Entry DOI: 10.7270/Q2GB27RX |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Rattus norvegicus) | BDBM50559030
(CHEMBL4748453)Show SMILES C[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)\C=N\NC(=O)COc1ccc(Cl)cc1Cl |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 2.57E+4 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111905
BindingDB Entry DOI: 10.7270/Q2GB27RX |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Rattus norvegicus) | BDBM50466400
(CHEMBL1818656)Show SMILES CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OCc1ccccc1 |r| Show InChI InChI=1S/C15H21NO6/c1-9(18)16-12-14(20)13(19)11(7-17)22-15(12)21-8-10-5-3-2-4-6-10/h2-6,11-15,17,19-20H,7-8H2,1H3,(H,16,18)/t11-,12-,13-,14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| Purchase
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 4.81E+4 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111905
BindingDB Entry DOI: 10.7270/Q2GB27RX |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Rattus norvegicus) | BDBM50559036
(CHEMBL4794885)Show SMILES Cc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)ccc2c3CCCCCc3c(=O)oc12 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 5.38E+4 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111905
BindingDB Entry DOI: 10.7270/Q2GB27RX |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Rattus norvegicus) | BDBM50559031
(CHEMBL2137967)Show SMILES CC(C)Oc1ccc(CNC(=O)C2CCCN(C2)S(=O)(=O)N2CCOCC2)cc1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 7.20E+4 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111905
BindingDB Entry DOI: 10.7270/Q2GB27RX |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Rattus norvegicus) | BDBM50559035
(CHEMBL4764217)Show SMILES OC[C@H]1O[C@@H](Oc2ccc3c(c2)oc(=O)c2ccccc32)[C@H](O)[C@@H](O)[C@@H]1O |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 1.06E+5 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111905
BindingDB Entry DOI: 10.7270/Q2GB27RX |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Rattus norvegicus) | BDBM50559037
(CHEMBL4753538)Show SMILES OC1(CC(=O)CC2(O)C(=O)Nc3ccccc23)C(=O)Nc2ccccc12 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 1.81E+5 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111905
BindingDB Entry DOI: 10.7270/Q2GB27RX |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Rattus norvegicus) | BDBM50245886
(4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymet...)Show SMILES OC[C@H]1O[C@@H](Oc2ccc(C=O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C13H16O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-5,9-13,15-18H,6H2/t9-,10-,11+,12-,13-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.28E+5 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111905
BindingDB Entry DOI: 10.7270/Q2GB27RX |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Rattus norvegicus) | BDBM50559033
(CHEMBL4761604)Show SMILES CNS(=O)(=O)c1cn(CC(=O)Nc2cc(C)cc(C)c2)cc1S(=O)(=O)NC | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 4.42E+5 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111905
BindingDB Entry DOI: 10.7270/Q2GB27RX |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Rattus norvegicus) | BDBM50559032
(CHEMBL1596034)Show SMILES CCC(C)c1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)cc1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 4.99E+5 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111905
BindingDB Entry DOI: 10.7270/Q2GB27RX |
More data for this
Ligand-Target Pair | |
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