BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 3 hits of kd for UniProtKB: P9WFY7   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
tRNA (guanine-N(1)-)-methyltransferase


(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
BDBM50519348
PNG
(CHEMBL4517402)
Show SMILES CCCCCCCCNCc1ccc(CNC(=O)c2csc3nc[nH]c(=O)c23)cc1
Show InChI InChI=1S/C23H30N4O2S/c1-2-3-4-5-6-7-12-24-13-17-8-10-18(11-9-17)14-25-21(28)19-15-30-23-20(19)22(29)26-16-27-23/h8-11,15-16,24H,2-7,12-14H2,1H3,(H,25,28)(H,26,27,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
n/an/an/a 190n/an/an/an/an/a



Singapore-MIT Alliance for Research and Technology

Curated by ChEMBL


Assay Description
Binding affinity to full length Mycobacterium tuberculosis tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surfac...


J Med Chem 62: 7788-7805 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00582
BindingDB Entry DOI: 10.7270/Q2C250TC
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
tRNA (guanine-N(1)-)-methyltransferase


(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
BDBM50009672
PNG
(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Show SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O
Show InChI InChI=1S/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6-,7+,9+,10+,13+/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/an/a 1.01E+4n/an/an/an/an/a



Singapore-MIT Alliance for Research and Technology

Curated by ChEMBL


Assay Description
Binding affinity to full length Mycobacterium tuberculosis tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surfac...


J Med Chem 62: 7788-7805 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00582
BindingDB Entry DOI: 10.7270/Q2C250TC
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
tRNA (guanine-N(1)-)-methyltransferase


(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
BDBM50519349
PNG
(CHEMBL2431997)
Show SMILES NC1CCN(Cc2ccc(CNC(=O)c3csc4nc[nH]c(=O)c34)cc2)CC1
Show InChI InChI=1S/C20H23N5O2S/c21-15-5-7-25(8-6-15)10-14-3-1-13(2-4-14)9-22-18(26)16-11-28-20-17(16)19(27)23-12-24-20/h1-4,11-12,15H,5-10,21H2,(H,22,26)(H,23,24,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
n/an/an/a 1.04E+4n/an/an/an/an/a



Singapore-MIT Alliance for Research and Technology

Curated by ChEMBL


Assay Description
Binding affinity to full length Mycobacterium tuberculosis tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surfac...


J Med Chem 62: 7788-7805 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00582
BindingDB Entry DOI: 10.7270/Q2C250TC
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)