Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
tRNA (guanine-N(1)-)-methyltransferase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50519348 (CHEMBL4517402) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a |
Singapore-MIT Alliance for Research and Technology Curated by ChEMBL | Assay Description Binding affinity to full length Mycobacterium tuberculosis tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surfac... | J Med Chem 62: 7788-7805 (2019) Article DOI: 10.1021/acs.jmedchem.9b00582 BindingDB Entry DOI: 10.7270/Q2C250TC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
tRNA (guanine-N(1)-)-methyltransferase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50009672 (AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a |
Singapore-MIT Alliance for Research and Technology Curated by ChEMBL | Assay Description Binding affinity to full length Mycobacterium tuberculosis tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surfac... | J Med Chem 62: 7788-7805 (2019) Article DOI: 10.1021/acs.jmedchem.9b00582 BindingDB Entry DOI: 10.7270/Q2C250TC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
tRNA (guanine-N(1)-)-methyltransferase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50519349 (CHEMBL2431997) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | n/a |
Singapore-MIT Alliance for Research and Technology Curated by ChEMBL | Assay Description Binding affinity to full length Mycobacterium tuberculosis tRNA (guanine(37)-N1)-methyltransferase expressed in Escherichia coli BL21 (DE3) by surfac... | J Med Chem 62: 7788-7805 (2019) Article DOI: 10.1021/acs.jmedchem.9b00582 BindingDB Entry DOI: 10.7270/Q2C250TC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |