Compile Data Set for Download or QSAR

Found 20 hits of ki for UniProtKB: P22909   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554696 (CHEMBL4749860) Show SMILES NCC1Cc2ccccc2CN1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50597775 (CHEMBL5198566) Show SMILES Nc1ncc(\C=C2/CCc3c(O)cccc3C2=O)cn1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113964 BindingDB Entry DOI: 10.7270/Q2BP06TV
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554684 (CHEMBL4796664) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCCCCNCC2Cc3ccccc3CN2)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554685 (CHEMBL4749263) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCCCCCNCC2Cc3ccccc3CN2)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50597773 (CHEMBL4535634) Show SMILES Oc1cccc(\C=C2/CCc3c(O)cccc3C2=O)c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113964 BindingDB Entry DOI: 10.7270/Q2BP06TV
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554689 (CHEMBL4754656) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCCCNCC2Cc3ccccc3CN2)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50597774 (CHEMBL5178192) Show SMILES Oc1ccc(\C=C2/CCc3c(O)cccc3C2=O)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113964 BindingDB Entry DOI: 10.7270/Q2BP06TV
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554691 (CHEMBL4764318) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCCNCC2Cc3ccccc3CN2)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554690 (CHEMBL4782649) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCCNCC2Cc3ccc(Cl)cc3CN2)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554694 (CHEMBL4740168) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCNCC2Cc3ccccc3CN2)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554692 (CHEMBL4751862) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCNCC2Cc3ccc(Cl)cc3CN2)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554686 (CHEMBL4754362) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCCNCC2CNCc3ccccc23)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50077537 ((+)-(7-nitro-1,2,3,4-tetrahydroisoquinolin-3-yl)me...) Show SMILES OCC1Cc2ccc(cc2CN1)[N+]([O-])=O Show InChI InChI=1S/C10H12N2O3/c13-6-9-3-7-1-2-10(12(14)15)4-8(7)5-11-9/h1-2,4,9,11,13H,3,5-6H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554695 (CHEMBL4760727) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCCNCC2Cc3ccc(cc3CN2)[N+]([O-])=O)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554683 (CHEMBL4783068) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCNCC2CNCc3ccccc23)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554693 (CHEMBL4800292) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCNCC2Cc3ccc(cc3CN2)[N+]([O-])=O)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50597772 (CHEMBL5170103) Show SMILES Oc1cccc2C(=O)\C(CCc12)=C\c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113964 BindingDB Entry DOI: 10.7270/Q2BP06TV
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50554681 (CHEMBL4795252) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCCNC(=O)C2Cc3ccccc3CN2)[C@@H](O)[C@H]1O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50023452 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES NC(=O)C1Cc2ccccc2CN1 Show InChI InChI=1S/C10H12N2O/c11-10(13)9-5-7-3-1-2-4-8(7)6-12-9/h1-4,9,12H,5-6H2,(H2,11,13)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus)	BDBM50294573 ((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-((2-amin...) Show SMILES NCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C12H18N6O3S/c13-1-2-22-3-6-8(19)9(20)12(21-6)18-5-17-7-10(14)15-4-16-11(7)18/h4-6,8-9,12,19-20H,1-3,13H2,(H2,14,15,16)/t6-,8-,9-,12-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.10E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01475 BindingDB Entry DOI: 10.7270/Q2MK6HJQ
					More data for this Ligand-Target Pair