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Target
Sequence
Name
&
Ki
IC50
Kd
EC50
Rate constants
ΔG°
ΔH°
-TΔS°
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/
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Ki
IC50
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EC50
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Compile Data Set for Download or QSAR
Found
30
hits of ic50 for UniProtKB:
P05198
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570964
(CHEMBL4857782)
Show SMILES
CCc1cc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)ccc1-c1cnc(N)c(c1)C(=O)NC(C)C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
Purchase
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
9
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570960
(CHEMBL4858308)
Show SMILES
CCc1cccc(c1)[C@@H](O)C(=O)Nc1ccc(c(C)c1)-c1cnc(N)c(c1)C(=O)NC(C)C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
18
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570963
(CHEMBL4848143)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1Cl |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
23
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570956
(CHEMBL4869882)
Show SMILES
Cc1cc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)ccc1-c1cnc(N)c(c1)C(=O)NC1CC1 |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/a
n/a
27
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570941
(CHEMBL4862478)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
33
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570972
(CHEMBL4848359)
Show SMILES
CNC(=O)c1nc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
40
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570958
(CHEMBL4853221)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cccc(Cl)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
40
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570966
(CHEMBL4861671)
Show SMILES
CC(C)NC(=O)c1nc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
42
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570955
(CHEMBL4863698)
Show SMILES
CCNC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
45
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570952
(CHEMBL4870100)
Show SMILES
CC(C)OC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
49
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570959
(CHEMBL4870780)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cccc(C)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
54
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570953
(CHEMBL4875875)
Show SMILES
CNC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
58
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570962
(CHEMBL4851480)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1F |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
72
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570957
(CHEMBL4876496)
Show SMILES
Cc1cc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)ccc1-c1cnc(N)c(c1)C(=O)NC(C)(C)C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
114
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570968
(CHEMBL4854504)
Show SMILES
CC(C)NC(=O)c1cncc(c1)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
181
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570942
(CHEMBL4852735)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
187
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570943
(CHEMBL4870495)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2ccccc2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
198
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570944
(CHEMBL4866245)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)Cc2ccccc2)cc1C
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
307
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570961
(CHEMBL4846663)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1 |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
313
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570965
(CHEMBL4870565)
Show SMILES
COc1cc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)ccc1-c1cnc(N)c(c1)C(=O)NC(C)C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
366
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570969
(CHEMBL4849149)
Show SMILES
CC(C)NC(=O)c1cc(cnc1C)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
638
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570948
(CHEMBL4868021)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@](C)(O)c2ccccc2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
2.13E+3
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570954
(CHEMBL4876223)
Show SMILES
CN(C)C(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
2.22E+3
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570946
(CHEMBL4853233)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)Nc2ccccc2)cc1C
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
2.36E+3
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570949
(CHEMBL4848921)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@@](C)(O)c2ccccc2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
3.02E+3
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570947
(CHEMBL4854364)
Show SMILES
CO[C@@H](C(=O)Nc1ccc(c(C)c1)-c1cnc(N)c(c1)C(=O)NC(C)C)c1ccccc1 |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
3.34E+3
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570970
(CHEMBL4858598)
Show SMILES
CNc1ncc(cc1C(=O)NC(C)C)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
4.03E+3
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570967
(CHEMBL4878188)
Show SMILES
CC(C)NC(=O)c1cc(nnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
7.65E+3
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570971
(CHEMBL4853611)
Show SMILES
Cc1cc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)ccc1-c1ccc(N)nc1 |r|
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
>1.00E+4
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2 subunit 1
(Homo sapiens)
BDBM50570945
(CHEMBL4856844)
Show SMILES
CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)Oc2ccccc2)cc1C
Show InChI
PDB
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
>1.00E+4
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2021.128058
BindingDB Entry DOI:
10.7270/Q26W9FWW
More data for this
Ligand-Target Pair
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