Compile Data Set for Download or QSAR

Found 381 hits of ic50 for UniProtKB: P03433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50509159 (CHEMBL4588964) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C13H8F3NO4/c14-13(15,16)7-4-2-1-3-6(7)8-5-9(18)11(19)10(17-8)12(20)21/h1-5,19H,(H,17,18)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509161 (CHEMBL4563716) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1cccc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9N5O4/c19-9-5-8(14-10(11(9)20)13(21)22)6-2-1-3-7(4-6)12-15-17-18-16-12/h1-5,20H,(H,14,19)(H,21,22)(H,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509167 (CHEMBL4539596) Show SMILES CCc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C14H13NO4/c1-2-8-5-3-4-6-9(8)10-7-11(16)13(17)12(15-10)14(18)19/h3-7,17H,2H2,1H3,(H,15,16)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509165 (CHEMBL4459575) Show SMILES OC(=O)c1ccc(cc1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H9NO6/c15-9-5-8(14-10(11(9)16)13(19)20)6-1-3-7(4-2-6)12(17)18/h1-5,16H,(H,14,15)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509155 (CHEMBL4440123) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9N5O4/c19-9-5-8(14-10(11(9)20)13(21)22)6-1-3-7(4-2-6)12-15-17-18-16-12/h1-5,20H,(H,14,19)(H,21,22)(H,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509169 (CHEMBL4545631) Show SMILES Cc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-4-2-3-5-8(7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509169 (CHEMBL4545631) Show SMILES Cc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-4-2-3-5-8(7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509159 (CHEMBL4588964) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C13H8F3NO4/c14-13(15,16)7-4-2-1-3-6(7)8-5-9(18)11(19)10(17-8)12(20)21/h1-5,19H,(H,17,18)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509167 (CHEMBL4539596) Show SMILES CCc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C14H13NO4/c1-2-8-5-3-4-6-9(8)10-7-11(16)13(17)12(15-10)14(18)19/h3-7,17H,2H2,1H3,(H,15,16)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509165 (CHEMBL4459575) Show SMILES OC(=O)c1ccc(cc1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H9NO6/c15-9-5-8(14-10(11(9)16)13(19)20)6-1-3-7(4-2-6)12(17)18/h1-5,16H,(H,14,15)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509161 (CHEMBL4563716) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1cccc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9N5O4/c19-9-5-8(14-10(11(9)20)13(21)22)6-2-1-3-7(4-6)12-15-17-18-16-12/h1-5,20H,(H,14,19)(H,21,22)(H,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	>2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509155 (CHEMBL4440123) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9N5O4/c19-9-5-8(14-10(11(9)20)13(21)22)6-1-3-7(4-2-6)12-15-17-18-16-12/h1-5,20H,(H,14,19)(H,21,22)(H,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509160 (CHEMBL4570983) Show SMILES COc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO5/c1-19-10-5-3-2-4-7(10)8-6-9(15)12(16)11(14-8)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509170 (CHEMBL4440338) Show SMILES OC(=O)c1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H9NO6/c15-9-5-8(14-10(11(9)16)13(19)20)6-2-1-3-7(4-6)12(17)18/h1-5,16H,(H,14,15)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509170 (CHEMBL4440338) Show SMILES OC(=O)c1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H9NO6/c15-9-5-8(14-10(11(9)16)13(19)20)6-2-1-3-7(4-6)12(17)18/h1-5,16H,(H,14,15)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50612273 (BALOXAVIR | Baloxavir | S-033447) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PDB UniChem	PDB	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509160 (CHEMBL4570983) Show SMILES COc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO5/c1-19-10-5-3-2-4-7(10)8-6-9(15)12(16)11(14-8)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509166 (CHEMBL4550646) Show SMILES CSc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4S/c1-19-10-5-3-2-4-7(10)8-6-9(15)12(16)11(14-8)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509157 (CHEMBL4530222) Show SMILES CC(C)c1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C15H15NO4/c1-8(2)9-5-3-4-6-10(9)11-7-12(17)14(18)13(16-11)15(19)20/h3-8,18H,1-2H3,(H,16,17)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509166 (CHEMBL4550646) Show SMILES CSc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4S/c1-19-10-5-3-2-4-7(10)8-6-9(15)12(16)11(14-8)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509157 (CHEMBL4530222) Show SMILES CC(C)c1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C15H15NO4/c1-8(2)9-5-3-4-6-10(9)11-7-12(17)14(18)13(16-11)15(19)20/h3-8,18H,1-2H3,(H,16,17)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509172 (CHEMBL4553243) Show SMILES Cc1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-3-2-4-8(5-7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509172 (CHEMBL4553243) Show SMILES Cc1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-3-2-4-8(5-7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50508967 (CHEMBL3944613) Show SMILES OC(=O)c1cn(CC2(CCCC2)n2ccc3cccnc23)cc(O)c1=O Show InChI InChI=1S/C19H19N3O4/c23-15-11-21(10-14(16(15)24)18(25)26)12-19(6-1-2-7-19)22-9-5-13-4-3-8-20-17(13)22/h3-5,8-11,23H,1-2,6-7,12H2,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company Curated by ChEMBL					Assay Description Inhibition of Influenza A virus CEN				J Med Chem 62: 8101-8114 (2019) Article DOI: 10.1021/acs.jmedchem.9b00861 BindingDB Entry DOI: 10.7270/Q2K35XZJ
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509173 (CHEMBL4469796) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1 Show InChI InChI=1S/C12H9NO4/c14-9-6-8(7-4-2-1-3-5-7)13-10(11(9)15)12(16)17/h1-6,15H,(H,13,14)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509173 (CHEMBL4469796) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1 Show InChI InChI=1S/C12H9NO4/c14-9-6-8(7-4-2-1-3-5-7)13-10(11(9)15)12(16)17/h1-6,15H,(H,13,14)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509168 (CHEMBL4460007) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C18H13NO5/c20-14-10-13(19-16(17(14)21)18(22)23)12-8-4-5-9-15(12)24-11-6-2-1-3-7-11/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509154 (CHEMBL4453833) Show SMILES CC(C)c1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C15H15NO4/c1-8(2)9-4-3-5-10(6-9)11-7-12(17)14(18)13(16-11)15(19)20/h3-8,18H,1-2H3,(H,16,17)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509168 (CHEMBL4460007) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C18H13NO5/c20-14-10-13(19-16(17(14)21)18(22)23)12-8-4-5-9-15(12)24-11-6-2-1-3-7-11/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509154 (CHEMBL4453833) Show SMILES CC(C)c1cccc(c1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C15H15NO4/c1-8(2)9-4-3-5-10(6-9)11-7-12(17)14(18)13(16-11)15(19)20/h3-8,18H,1-2H3,(H,16,17)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509152 (CHEMBL4535893) Show SMILES Cc1ccc(cc1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-2-4-8(5-3-7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509152 (CHEMBL4535893) Show SMILES Cc1ccc(cc1)-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO4/c1-7-2-4-8(5-3-7)9-6-10(15)12(16)11(14-9)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM105203 (6-(4-Fluorophenyl)-3-hydroxy-5-[4-(1H-1, 2, 3, 4-t...) Show SMILES Oc1cc(-c2ccc(cc2)-c2nnn[nH]2)c([nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C18H12FN5O2/c19-13-7-5-11(6-8-13)16-14(9-15(25)18(26)20-16)10-1-3-12(4-2-10)17-21-23-24-22-17/h1-9,25H,(H,20,26)(H,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company Curated by ChEMBL					Assay Description Inhibition of Influenza A virus CEN				J Med Chem 62: 8101-8114 (2019) Article DOI: 10.1021/acs.jmedchem.9b00861 BindingDB Entry DOI: 10.7270/Q2K35XZJ
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM105203 (6-(4-Fluorophenyl)-3-hydroxy-5-[4-(1H-1, 2, 3, 4-t...) Show SMILES Oc1cc(-c2ccc(cc2)-c2nnn[nH]2)c([nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C18H12FN5O2/c19-13-7-5-11(6-8-13)16-14(9-15(25)18(26)20-16)10-1-3-12(4-2-10)17-21-23-24-22-17/h1-9,25H,(H,20,26)(H,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chiba University Curated by ChEMBL					Assay Description Inhibition of Influenza A/Puerto Rico/8/34 (H1N1) PA N-terminal domain endonuclease activity expressed in Escherichia coli BL21 (RIL) cells using (6-...				Bioorg Med Chem 23: 5466-75 (2015) Article DOI: 10.1016/j.bmc.2015.07.046 BindingDB Entry DOI: 10.7270/Q2N87CK3
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50409783 (CHEMBL1626982 | CHEMBL2068710 | CHEMBL2068711 | CH...) Show SMILES [O-]C(=O)C(=O)[CH-]C(=O)C1(Cc2ccc(Cl)cc2)CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C23H23ClNO4/c24-19-8-6-17(7-9-19)15-23(21(27)14-20(26)22(28)29)10-12-25(13-11-23)16-18-4-2-1-3-5-18/h1-9,14H,10-13,15-16H2,(H,28,29)/q-1/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Roche Discovery Welwyn Curated by ChEMBL					Assay Description Inhibitory concentration against cap-dependent endonuclease activity of influenza A/PR/8/34 RNP				J Med Chem 46: 1153-64 (2003) Article DOI: 10.1021/jm020334u BindingDB Entry DOI: 10.7270/Q22J6B6V
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509158 (CHEMBL4438546) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C18H13NO5/c20-15-10-14(19-16(17(15)21)18(22)23)11-5-4-8-13(9-11)24-12-6-2-1-3-7-12/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50508966 (CHEMBL4452342) Show SMILES CN(Cc1cc(=O)c(O)cn1-c1ccc(cc1)-c1nnn[nH]1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H17ClN6O2/c1-26(15-8-4-14(21)5-9-15)11-17-10-18(28)19(29)12-27(17)16-6-2-13(3-7-16)20-22-24-25-23-20/h2-10,12,29H,11H2,1H3,(H,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...				J Med Chem 59: 6444-54 (2016) Article DOI: 10.1021/acs.jmedchem.6b00628 BindingDB Entry DOI: 10.7270/Q2W95DPM
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50508966 (CHEMBL4452342) Show SMILES CN(Cc1cc(=O)c(O)cn1-c1ccc(cc1)-c1nnn[nH]1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H17ClN6O2/c1-26(15-8-4-14(21)5-9-15)11-17-10-18(28)19(29)12-27(17)16-6-2-13(3-7-16)20-22-24-25-23-20/h2-10,12,29H,11H2,1H3,(H,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...				J Med Chem 59: 6444-54 (2016) Article DOI: 10.1021/acs.jmedchem.6b00628 BindingDB Entry DOI: 10.7270/Q2W95DPM
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50508966 (CHEMBL4452342) Show SMILES CN(Cc1cc(=O)c(O)cn1-c1ccc(cc1)-c1nnn[nH]1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H17ClN6O2/c1-26(15-8-4-14(21)5-9-15)11-17-10-18(28)19(29)12-27(17)16-6-2-13(3-7-16)20-22-24-25-23-20/h2-10,12,29H,11H2,1H3,(H,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company Curated by ChEMBL					Assay Description Inhibition of Influenza A virus CEN				J Med Chem 62: 8101-8114 (2019) Article DOI: 10.1021/acs.jmedchem.9b00861 BindingDB Entry DOI: 10.7270/Q2K35XZJ
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509158 (CHEMBL4438546) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C18H13NO5/c20-15-10-14(19-16(17(15)21)18(22)23)11-5-4-8-13(9-11)24-12-6-2-1-3-7-12/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509156 (CHEMBL4170746) Show SMILES Cc1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C7H7NO4/c1-3-2-4(9)6(10)5(8-3)7(11)12/h2,10H,1H3,(H,8,9)(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509156 (CHEMBL4170746) Show SMILES Cc1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C7H7NO4/c1-3-2-4(9)6(10)5(8-3)7(11)12/h2,10H,1H3,(H,8,9)(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509171 (CHEMBL4476501) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C18H13NO5/c20-15-10-14(19-16(17(15)21)18(22)23)11-6-8-13(9-7-11)24-12-4-2-1-3-5-12/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509171 (CHEMBL4476501) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C18H13NO5/c20-15-10-14(19-16(17(15)21)18(22)23)11-6-8-13(9-7-11)24-12-4-2-1-3-5-12/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50409783 (CHEMBL1626982 | CHEMBL2068710 | CHEMBL2068711 | CH...) Show SMILES [O-]C(=O)C(=O)[CH-]C(=O)C1(Cc2ccc(Cl)cc2)CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C23H23ClNO4/c24-19-8-6-17(7-9-19)15-23(21(27)14-20(26)22(28)29)10-12-25(13-11-23)16-18-4-2-1-3-5-18/h1-9,14H,10-13,15-16H2,(H,28,29)/q-1/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Roche Discovery Welwyn Curated by ChEMBL					Assay Description Inhibitory concentration against cap-dependent endonuclease activity of influenza A/PR/8/34 RNP				J Med Chem 46: 1153-64 (2003) Article DOI: 10.1021/jm020334u BindingDB Entry DOI: 10.7270/Q22J6B6V
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50536153 (CHEMBL4531327) Show SMILES Cc1cc(=O)c(O)cn1-c1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C13H11N5O2/c1-8-6-11(19)12(20)7-18(8)10-4-2-9(3-5-10)13-14-16-17-15-13/h2-7,20H,1H3,(H,14,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...				J Med Chem 59: 6444-54 (2016) Article DOI: 10.1021/acs.jmedchem.6b00628 BindingDB Entry DOI: 10.7270/Q2W95DPM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50536153 (CHEMBL4531327) Show SMILES Cc1cc(=O)c(O)cn1-c1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C13H11N5O2/c1-8-6-11(19)12(20)7-18(8)10-4-2-9(3-5-10)13-14-16-17-15-13/h2-7,20H,1H3,(H,14,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...				J Med Chem 59: 6444-54 (2016) Article DOI: 10.1021/acs.jmedchem.6b00628 BindingDB Entry DOI: 10.7270/Q2W95DPM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polymerase acidic protein (Hepatitis C virus)	BDBM50509153 (CHEMBL4551356) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccc(cc1C(F)(F)F)-c1nnn[nH]1 Show InChI InChI=1S/C14H8F3N5O4/c15-14(16,17)7-3-5(12-19-21-22-20-12)1-2-6(7)8-4-9(23)11(24)10(18-8)13(25)26/h1-4,24H,(H,18,23)(H,25,26)(H,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509153 (CHEMBL4551356) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccc(cc1C(F)(F)F)-c1nnn[nH]1 Show InChI InChI=1S/C14H8F3N5O4/c15-14(16,17)7-3-5(12-19-21-22-20-12)1-2-6(7)8-4-9(23)11(24)10(18-8)13(25)26/h1-4,24H,(H,18,23)(H,25,26)(H,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50508959 (CHEMBL4439208) Show SMILES COCCN1C[C@H](C(c2ccccc2)c2ccccc2)n2cc(C(O)=O)c(=O)c(O)c2C1=O |r| Show InChI InChI=1S/C25H24N2O6/c1-33-13-12-26-15-19(20(16-8-4-2-5-9-16)17-10-6-3-7-11-17)27-14-18(25(31)32)22(28)23(29)21(27)24(26)30/h2-11,14,19-20,29H,12-13,15H2,1H3,(H,31,32)/t19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company Curated by ChEMBL					Assay Description Inhibition of Influenza A virus (A/WSN/1933(H1N1)) CEN using m7G[5']-ppp-[5'] [m2'-O]GAA UAU(-Cy3) GCA UCA CUA GUA AGC UUU GCU CUA(-BHQ2)-3' as subst...				J Med Chem 62: 8101-8114 (2019) Article DOI: 10.1021/acs.jmedchem.9b00861 BindingDB Entry DOI: 10.7270/Q2K35XZJ
					More data for this Ligand-Target Pair

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