Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50117957 (CHEMBL123678 | {4-[3-(6,7-Diethoxy-quinazolin-4-yl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat double mutant (Gln50Lys Gln55His) enzyme using malachite... | J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303871 (4-Amino-7-cyclopropyl-5-fluoro-1-isobutyl-2-[5-(2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303879 (4-Amino-5-fluoro-7-[3-(N,N-dimethylamino)propyl]-1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303878 (4-Amino-7-(3-hydroxypropyl)-5-fluoro-1-isobutyl-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303880 (4-Amino-5-fluoro-7-(4-chlorobutyl)-1-isobutyl-2-[5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50117955 (4-[3-(6,7-Diethoxy-quinazolin-4-ylamino)-phenyl]-t...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat double mutant (Gln50Lys Gln55His) enzyme using malachite... | J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303854 (5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303875 (4-Amino-5-fluoro-7-(n-propyl)-1-isobutyl-2-[5-(2-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50117947 ((6,7-Diethoxy-quinazolin-4-yl)-[3-(2-methyl-thiazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat double mutant (Gln50Lys Gln55His) enzyme using malachite... | J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303861 (4-Amino-5-fluoro-1-(2-ethylbutyl)-2-[5-(2-phosphon...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303870 (4-Amino-7-vinyl-5-fluoro-1-isobutyl-2-[5-(2-phosph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303872 (4-Amino-7-phenyl-5-fluoro-1-isobutyl-2-[5-(2-phosp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50277565 (5-(6-amino-9-neopentyl-9H-purin-8-yl)furan-2-ylpho...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase | J Med Chem 52: 2880-98 (2009) Article DOI: 10.1021/jm900078f BindingDB Entry DOI: 10.7270/Q2V40V20 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303873 (4-Amino-7-(p-fluorophenyl)-5-fluoro-1-isobutyl-2-[...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303876 (4-Amino-7-(3,3-dimethyl-n-butyl)-5-fluoro-1-isobut...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303868 (4-Amino-5-fluoro-6-chloro-1-isobutyl-2-[5-(2-phosp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50277613 (CHEMBL484332 | {5-[6-Amino-9-(3-chloro-2,2-dimethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase | J Med Chem 52: 2880-98 (2009) Article DOI: 10.1021/jm900078f BindingDB Entry DOI: 10.7270/Q2V40V20 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303874 (4-Amino-7-(p-chlorophenyl)-5-fluoro-1-isobutyl-2-[...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303883 (4-Amino-L-propyl-2-[2-(5-phosphono)furanyl]benzimi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303866 (4-Amino-5-fluoro-7-chloro-1-isobutyl-2-[5-(2-phosp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303865 (4-Amino-5,7-dichloro-1-isobutyl-2-[5-(2-phosphono)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303864 (4-Amino-5,7-dibromo-1-isobutyl-2-[2-(5-phosphono)f...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303859 (4-Amino-7-bromo-1-isobutyl-2-[2-(5-phosphono)furan...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303857 (4-Amino-7-chloro-1-isobutyl-2-[2-(5-phosphono)fura...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303886 (4-Amino-1-cyclobutylmethyl-2-[2-(5-phosphono)furan...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303887 (4-Amino-1-cyclopentylmethyl-2-[2-(5-phosphono)fura...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303893 (4-Amino-1-norbornylmethyl-2-[2-(5-phosphono)furany...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303892 (4-Amino-5-methoxy-1-isobutyl-2-[5-(2-phosphono)fur...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303856 (4-Amino-5-chloro-1-isobutyl-2-[2-(5-phosphono)fura...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303867 (4-Amino-5-fluoro-7-bromo-1-isobutyl-2-[5-(2-phosph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303877 (4-Amino-7-(4-methylpentyl)-5-fluoro-1-isobutyl-2-[...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303863 (4-Amino-5-fluoro-1-cyclopropylmethyl-2-[5-(2-phosp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303860 (4-Amino-5-fluoro-1-isobutyl-2-[5-(2-phosphono)fura...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303862 (4-Amino-5-fluoro-1-(3-pentyl)-2-[5-(2-phosphono)fu...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50117957 (CHEMBL123678 | {4-[3-(6,7-Diethoxy-quinazolin-4-yl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat single mutant (Gln55His) enzyme using malachite green as... | J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50117955 (4-[3-(6,7-Diethoxy-quinazolin-4-ylamino)-phenyl]-t...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat single mutant (Gln55His) enzyme using malachite green as... | J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50117947 ((6,7-Diethoxy-quinazolin-4-yl)-[3-(2-methyl-thiazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat single mutant(Gln55His) enzyme using malachite green ass... | J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50303884 (4-Amino-l-isobutyl-2-[2-(5-phosphono)furanyl]benzi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase 1 | J Med Chem 53: 441-51 (2010) Article DOI: 10.1021/jm901420x BindingDB Entry DOI: 10.7270/Q2N58MFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50277660 (CHEMBL483354 | {5-[6-Amino-9-(2,2-dimethyl-propyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase | J Med Chem 52: 2880-98 (2009) Article DOI: 10.1021/jm900078f BindingDB Entry DOI: 10.7270/Q2V40V20 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50277564 (5-(6-amino-9-isobutyl-9H-purin-8-yl)furan-2-ylphos...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Metabasis Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver FBPase | J Med Chem 52: 2880-98 (2009) Article DOI: 10.1021/jm900078f BindingDB Entry DOI: 10.7270/Q2V40V20 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50117989 (4-[3-(2-Dimethylaminomethyl-6,7-diethoxy-quinazoli...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Concentration required for 50% Inhibition against recombinant wild type pig enzyme (F16BP) Fructose-1,6-bisphosphatase | J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50117955 (4-[3-(6,7-Diethoxy-quinazolin-4-ylamino)-phenyl]-t...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat wild type enzyme using malachite green assay | J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50095259 ((6,7-Dimethoxy-quinazolin-4-yl)-(3-ethynyl-phenyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Compound was evaluated for its concentration required to inhibit the rat liver F16BPase | Bioorg Med Chem Lett 11: 17-21 (2001) BindingDB Entry DOI: 10.7270/Q2HD7W52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM3532 (CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Compound was evaluated for its concentration required to inhibit the rat liver F16BPase | Bioorg Med Chem Lett 11: 17-21 (2001) BindingDB Entry DOI: 10.7270/Q2HD7W52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM3032 (CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Compound was evaluated for its concentration required to inhibit the rat liver F16BPase | Bioorg Med Chem Lett 11: 17-21 (2001) BindingDB Entry DOI: 10.7270/Q2HD7W52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50095256 ((6,7-Dimethoxy-quinazolin-4-yl)-(3-ethynyl-4-fluor...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Compound was evaluated for its concentration required to inhibit the rat liver F16BPase | Bioorg Med Chem Lett 11: 17-21 (2001) BindingDB Entry DOI: 10.7270/Q2HD7W52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50095261 ((3-Chloro-phenyl)-(6,7-diethoxy-quinazolin-4-yl)-a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Compound was evaluated for its concentration required to inhibit the rat liver F16BPase | Bioorg Med Chem Lett 11: 17-21 (2001) BindingDB Entry DOI: 10.7270/Q2HD7W52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM3556 (4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Compound was evaluated for its concentration required to inhibit the rat liver F16BPase | Bioorg Med Chem Lett 11: 17-21 (2001) BindingDB Entry DOI: 10.7270/Q2HD7W52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50095266 ((3-Chloro-4-fluoro-phenyl)-(6,7-diethoxy-quinazoli...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Compound was evaluated for its concentration required to inhibit the rat liver F16BPase | Bioorg Med Chem Lett 11: 17-21 (2001) BindingDB Entry DOI: 10.7270/Q2HD7W52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fructose-1,6-bisphosphatase 1 (Rattus norvegicus) | BDBM50117955 (4-[3-(6,7-Diethoxy-quinazolin-4-ylamino)-phenyl]-t...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat single mutant (Gln50Lys) enzyme using malachite green as... | J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0 | |||||||||||
More data for this Ligand-Target Pair |
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