Compile Data Set for Download or QSAR

Found 11 hits of ki for UniProtKB: P24593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50106431 (1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description The compound was tested for binding affinity against Insulin-like growth factor binding protein 5				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50106431 (1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)				Bioorg Med Chem Lett 13: 1931-4 (2003) BindingDB Entry DOI: 10.7270/Q2XD1138
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50106443 (1-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-isoquinolin...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(Cc2ccc(O)c(O)c2)n1 Show InChI InChI=1S/C17H13NO6/c19-13-2-1-8(4-14(13)20)3-11-10-7-16(22)15(21)6-9(10)5-12(18-11)17(23)24/h1-2,4-7,19-22H,3H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)				Bioorg Med Chem Lett 13: 1931-4 (2003) BindingDB Entry DOI: 10.7270/Q2XD1138
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50128459 (4-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-quinoline-2...) Show SMILES OC(=O)c1cc(Cc2ccc(O)c(O)c2)c2cc(O)c(O)cc2n1 Show InChI InChI=1S/C17H13NO6/c19-13-2-1-8(4-14(13)20)3-9-5-12(17(23)24)18-11-7-16(22)15(21)6-10(9)11/h1-2,4-7,19-22H,3H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)				Bioorg Med Chem Lett 13: 1931-4 (2003) BindingDB Entry DOI: 10.7270/Q2XD1138
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50106432 ((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...) Show SMILES Oc1ccc(cc1O)C(=O)c1[nH]c(=O)cc2cc(O)c(O)cc12 Show InChI InChI=1S/C16H11NO6/c18-10-2-1-7(3-11(10)19)16(23)15-9-6-13(21)12(20)4-8(9)5-14(22)17-15/h1-6,18-21H,(H,17,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description The compound was tested for binding affinity against Insulin-like growth factor binding protein 5				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50128462 (7-Amino-4-(3,4-dihydroxy-benzyl)-6-hydroxy-quinoli...) Show SMILES Nc1cc2nc(cc(Cc3ccc(O)c(O)c3)c2cc1O)C(O)=O Show InChI InChI=1S/C17H14N2O5/c18-11-7-12-10(6-15(11)21)9(5-13(19-12)17(23)24)3-8-1-2-14(20)16(22)4-8/h1-2,4-7,20-22H,3,18H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)				Bioorg Med Chem Lett 13: 1931-4 (2003) BindingDB Entry DOI: 10.7270/Q2XD1138
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50128461 (4-(3,4-Dihydroxy-benzyl)-7-fluoro-6-hydroxy-quinol...) Show SMILES OC(=O)c1cc(Cc2ccc(O)c(O)c2)c2cc(O)c(F)cc2n1 Show InChI InChI=1S/C17H12FNO5/c18-11-7-12-10(6-15(11)21)9(5-13(19-12)17(23)24)3-8-1-2-14(20)16(22)4-8/h1-2,4-7,20-22H,3H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)				Bioorg Med Chem Lett 13: 1931-4 (2003) BindingDB Entry DOI: 10.7270/Q2XD1138
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50128458 (4-(3,4-Dihydroxy-benzyl)-6-hydroxy-quinoline-2,7-d...) Show SMILES OC(=O)c1cc(Cc2ccc(O)c(O)c2)c2cc(O)c(cc2n1)C(O)=O Show InChI InChI=1S/C18H13NO7/c20-14-2-1-8(4-16(14)22)3-9-5-13(18(25)26)19-12-6-11(17(23)24)15(21)7-10(9)12/h1-2,4-7,20-22H,3H2,(H,23,24)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)				Bioorg Med Chem Lett 13: 1931-4 (2003) BindingDB Entry DOI: 10.7270/Q2XD1138
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50128456 (7-Chloro-4-(3,4-dihydroxy-benzyl)-6-hydroxy-quinol...) Show SMILES OC(=O)c1cc(Cc2ccc(O)c(O)c2)c2cc(O)c(Cl)cc2n1 Show InChI InChI=1S/C17H12ClNO5/c18-11-7-12-10(6-15(11)21)9(5-13(19-12)17(23)24)3-8-1-2-14(20)16(22)4-8/h1-2,4-7,20-22H,3H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)				Bioorg Med Chem Lett 13: 1931-4 (2003) BindingDB Entry DOI: 10.7270/Q2XD1138
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50128457 (7-Amino-4-(3,4-dihydroxy-benzyl)-6-methoxy-quinoli...) Show SMILES COc1cc2c(Cc3ccc(O)c(O)c3)cc(nc2cc1N)C(O)=O Show InChI InChI=1S/C18H16N2O5/c1-25-17-7-11-10(4-9-2-3-15(21)16(22)5-9)6-14(18(23)24)20-13(11)8-12(17)19/h2-3,5-8,21-22H,4,19H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)				Bioorg Med Chem Lett 13: 1931-4 (2003) BindingDB Entry DOI: 10.7270/Q2XD1138
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 5 (Homo sapiens (Human))	BDBM50128460 (4-(3,4-Dihydroxy-benzyl)-quinoline-2,6-dicarboxyli...) Show SMILES OC(=O)c1ccc2nc(cc(Cc3ccc(O)c(O)c3)c2c1)C(O)=O Show InChI InChI=1S/C18H13NO6/c20-15-4-1-9(6-16(15)21)5-11-8-14(18(24)25)19-13-3-2-10(17(22)23)7-12(11)13/h1-4,6-8,20-21H,5H2,(H,22,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)				Bioorg Med Chem Lett 13: 1931-4 (2003) BindingDB Entry DOI: 10.7270/Q2XD1138
					More data for this Ligand-Target Pair