Found 9 hits of kd for UniProtKB: P04618 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein Rev
(Human immunodeficiency virus 1) | BDBM50097339
(CHEMBL415806 | Neamine derivative)Show SMILES C[C@@H](O)[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O Show InChI InChI=1S/C97H173N51O24/c1-46(133-72(156)60(27-30-66(98)150)142-79(163)59(25-13-41-130-96(118)119)145-86(170)70(101)47(2)149)71(155)134-51(17-5-33-122-88(102)103)73(157)137-58(24-12-40-129-95(116)117)81(165)148-65(44-68(100)152)85(169)141-55(21-9-37-126-92(110)111)76(160)136-52(18-6-34-123-89(104)105)74(158)135-53(19-7-35-124-90(106)107)75(159)138-57(23-11-39-128-94(114)115)80(164)147-64(43-48-45-132-50-16-4-3-15-49(48)50)84(168)140-56(22-10-38-127-93(112)113)78(162)144-62(29-32-69(153)154)82(166)139-54(20-8-36-125-91(108)109)77(161)143-61(28-31-67(99)151)83(167)146-63(87(171)172)26-14-42-131-97(120)121/h3-4,15-16,45-47,51-65,70,132,149H,5-14,17-44,101H2,1-2H3,(H2,98,150)(H2,99,151)(H2,100,152)(H,133,156)(H,134,155)(H,135,158)(H,136,160)(H,137,157)(H,138,159)(H,139,166)(H,140,168)(H,141,169)(H,142,163)(H,143,161)(H,144,162)(H,145,170)(H,146,167)(H,147,164)(H,148,165)(H,153,154)(H,171,172)(H4,102,103,122)(H4,104,105,123)(H4,106,107,124)(H4,108,109,125)(H4,110,111,126)(H4,112,113,127)(H4,114,115,128)(H4,116,117,129)(H4,118,119,130)(H4,120,121,131)/t46-,47+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,70-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| Purchase
CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a |
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
| Assay Description
Dissociation constant was determined for Rev Response Element RNA IIB |
Bioorg Med Chem Lett 11: 591-4 (2001)
BindingDB Entry DOI: 10.7270/Q2G44QT9 |
More data for this
Ligand-Target Pair | |
Protein Rev
(Human immunodeficiency virus 1) | BDBM50097337
(CHEMBL349996 | Neamine derivative)Show SMILES NC1CC(N)C(OC2OC(CNC(=O)C(CCCNC(N)=N)NC(=O)c3ccc4ccc5cccc6ccc3c4c56)C(O)C(O)C2N)C(O)C1O Show InChI InChI=1S/C35H46N8O8/c36-20-13-21(37)31(30(47)27(20)44)51-34-26(38)29(46)28(45)23(50-34)14-42-33(49)22(5-2-12-41-35(39)40)43-32(48)19-11-9-17-7-6-15-3-1-4-16-8-10-18(19)25(17)24(15)16/h1,3-4,6-11,20-23,26-31,34,44-47H,2,5,12-14,36-38H2,(H,42,49)(H,43,48)(H4,39,40,41) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a |
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
| Assay Description
Dissociation constant was determined for Rev Response Element RNA IIB |
Bioorg Med Chem Lett 11: 591-4 (2001)
BindingDB Entry DOI: 10.7270/Q2G44QT9 |
More data for this
Ligand-Target Pair | |
Protein Rev
(Human immunodeficiency virus 1) | BDBM50099375
(CHEMBL384228 | Neo-Neo dimer)Show SMILES NCC1OC(OC2C(CSCCOCCSSCCOCCSCC3OC(OC4C(O)C(O)CC(N)C4OC4OC(CN)C(O)C(O)C4N)C(O)C3OC3OC(CN)C(O)C(O)C3N)OC(OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)C2O)C(N)C(O)C1O Show InChI InChI=1S/C54H105N11O27S4/c55-11-21-33(69)37(73)27(62)49(81-21)87-43-18(60)9-17(59)31(67)47(43)91-53-41(77)45(89-51-29(64)39(75)35(71)23(13-57)83-51)25(85-53)15-93-5-1-79-3-7-95-96-8-4-80-2-6-94-16-26-46(90-52-30(65)40(76)36(72)24(14-58)84-52)42(78)54(86-26)92-48-32(68)20(66)10-19(61)44(48)88-50-28(63)38(74)34(70)22(12-56)82-50/h17-54,66-78H,1-16,55-65H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Tetsed for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropy |
Bioorg Med Chem Lett 11: 1127-31 (2001)
BindingDB Entry DOI: 10.7270/Q2W66M9H |
More data for this
Ligand-Target Pair | |
Protein Rev
(Human immunodeficiency virus 1) | BDBM50099377
(Aminoglycoside dimer analogue | CHEMBL3037952 | Ne...)Show SMILES NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CSCCOCCSSCCOCCSC[C@H]4O[C@@H](O[C@H]5[C@H](O)[C@@H](N)C[C@@H](N)[C@@H]5O[C@H]5O[C@H](CN)[C@@H](O)[C@H](O)[C@H]5N)[C@H](O)[C@@H]4O[C@H]4OC(CN)[C@@H](O)[C@H](O)[C@H]4N)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O |r| Show InChI InChI=1S/C49H97N11O22S4/c50-12-23-22(61)11-21(57)45(73-23)78-40-18(54)10-19(55)41(38(40)69)79-48-37(68)28(58)32(63)26(76-48)15-83-5-1-71-3-7-85-86-8-4-72-2-6-84-16-27-43(81-47-30(60)36(67)34(65)25(14-52)75-47)39(70)49(77-27)82-44-31(62)17(53)9-20(56)42(44)80-46-29(59)35(66)33(64)24(13-51)74-46/h17-49,61-70H,1-16,50-60H2/t17-,18-,19+,20+,21+,22-,23+,24+,25?,26+,27+,28-,29+,30+,31+,32+,33+,34+,35+,36+,37+,38-,39+,40+,41-,42-,43+,44-,45+,46+,47+,48+,49-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Tetsed for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropy |
Bioorg Med Chem Lett 11: 1127-31 (2001)
BindingDB Entry DOI: 10.7270/Q2W66M9H |
More data for this
Ligand-Target Pair | |
Protein Rev
(Human immunodeficiency virus 1) | BDBM19
((2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3...)Show SMILES NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
In vitro functional activity at Alpha-1D adrenergic receptor in rat aorta |
Bioorg Med Chem Lett 11: 1127-31 (2001)
BindingDB Entry DOI: 10.7270/Q2W66M9H |
More data for this
Ligand-Target Pair | |
Protein Rev
(Human immunodeficiency virus 1) | BDBM50097336
(CHEMBL152397 | Pyrene-1-carboxylic acid [(4R,5S,6S...)Show SMILES NC1CC(N)C(OC2OC(CNC(=O)c3ccc4ccc5cccc6ccc3c4c56)C(O)C(O)C2N)C(O)C1O Show InChI InChI=1S/C29H34N4O7/c30-17-10-18(31)27(26(37)23(17)34)40-29-22(32)25(36)24(35)19(39-29)11-33-28(38)16-9-7-14-5-4-12-2-1-3-13-6-8-15(16)21(14)20(12)13/h1-9,17-19,22-27,29,34-37H,10-11,30-32H2,(H,33,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a |
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human telomerase |
Bioorg Med Chem Lett 11: 591-4 (2001)
BindingDB Entry DOI: 10.7270/Q2G44QT9 |
More data for this
Ligand-Target Pair | |
Protein Rev
(Human immunodeficiency virus 1) | BDBM50099376
(Aminoglycoside dimer analogue | CHEMBL2368770)Show SMILES CN(C)C1=CC2Oc3cc(ccc3C(=C2C=C1)c1ccc(cc1C(O)=O)C(=O)NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@H](O[C@@H]3[C@H](O)[C@H](N)C[C@@H](N)[C@H]3O[C@H]3O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]3N)O[C@@H]2CO)[C@H](N)[C@H](O)[C@@H]1O)N(C)C |r,c:14,17,t:3| Show InChI InChI=1S/C48H67N7O18/c1-54(2)19-6-9-22-27(12-19)67-28-13-20(55(3)4)7-10-23(28)32(22)21-8-5-18(11-24(21)45(65)66)44(64)53-15-29-36(59)38(61)33(51)46(68-29)72-42-31(17-57)70-48(40(42)63)73-43-35(58)25(49)14-26(50)41(43)71-47-34(52)39(62)37(60)30(16-56)69-47/h5-13,25-27,29-31,33-43,46-48,56-63H,14-17,49-52H2,1-4H3,(H,53,64)(H,65,66)/t25-,26-,27?,29+,30+,31-,33-,34+,35-,36-,37-,38+,39-,40-,41-,42-,43-,46-,47-,48+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Tetsed for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropy |
Bioorg Med Chem Lett 11: 1127-31 (2001)
BindingDB Entry DOI: 10.7270/Q2W66M9H |
More data for this
Ligand-Target Pair | |
Protein Rev
(Human immunodeficiency virus 1) | BDBM50090266
(Aminoglycoside analogue | Tob-Tob dimer | Tobramyc...)Show SMILES NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CSCCOCCSSCCOCCSC[C@H]4O[C@H](O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6O[C@H](CN)[C@@H](O)C[C@H]6N)[C@@H]5O)[C@H](O)[C@@H](N)[C@@H]4O)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O |r| Show InChI InChI=1S/C44H88N10O18S4/c45-13-25-23(55)11-21(51)41(65-25)69-37-17(47)9-19(49)39(35(37)61)71-43-33(59)29(53)31(57)27(67-43)15-73-5-1-63-3-7-75-76-8-4-64-2-6-74-16-28-32(58)30(54)34(60)44(68-28)72-40-20(50)10-18(48)38(36(40)62)70-42-22(52)12-24(56)26(14-46)66-42/h17-44,55-62H,1-16,45-54H2/t17-,18-,19+,20+,21+,22+,23-,24-,25+,26+,27+,28+,29-,30-,31+,32+,33+,34+,35-,36-,37+,38+,39-,40-,41+,42+,43+,44+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 3.69E+3 | n/a | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Tetsed for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropy |
Bioorg Med Chem Lett 11: 1127-31 (2001)
BindingDB Entry DOI: 10.7270/Q2W66M9H |
More data for this
Ligand-Target Pair | |
Protein Rev
(Human immunodeficiency virus 1) | BDBM50366778
(47663 | Aktob | Nebcin | Nebicin | Nebramycin | Ne...)Show SMILES NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O |r| Show InChI InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 4.11E+3 | n/a | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Tetsed for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropy |
Bioorg Med Chem Lett 11: 1127-31 (2001)
BindingDB Entry DOI: 10.7270/Q2W66M9H |
More data for this
Ligand-Target Pair | |
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