Found 18 hits of ic50 data for polymerid = 50003232 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50352641
(CHEMBL1733803)Show InChI InChI=1S/C18H20N2O4S/c21-17(22)12-4-6-20(7-5-12)18-19-11-16(25-18)13-2-3-14-15(10-13)24-9-1-8-23-14/h2-3,10-12H,1,4-9H2,(H,21,22) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of fire fly luciferase |
J Med Chem 54: 6215-33 (2011)
Article DOI: 10.1021/jm200497t BindingDB Entry DOI: 10.7270/Q22F7NVF |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50261811
(CHEMBL467379 | N-(5-Phenylpyridin-2-yl)benzamide)Show InChI InChI=1S/C18H14N2O/c21-18(15-9-5-2-6-10-15)20-17-12-11-16(13-19-17)14-7-3-1-4-8-14/h1-13H,(H,19,20,21) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research
Curated by ChEMBL
| Assay Description Inhibition of firefly luciferase activity |
J Med Chem 51: 4724-9 (2008)
Article DOI: 10.1021/jm8004509 BindingDB Entry DOI: 10.7270/Q2BP02MH |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50272796
(3-Chloro-N-(5-phenylpyridin-2-yl)benzamide | CHEMB...)Show InChI InChI=1S/C18H13ClN2O/c19-16-8-4-7-14(11-16)18(22)21-17-10-9-15(12-20-17)13-5-2-1-3-6-13/h1-12H,(H,20,21,22) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research
Curated by ChEMBL
| Assay Description Inhibition of firefly luciferase activity |
J Med Chem 51: 4724-9 (2008)
Article DOI: 10.1021/jm8004509 BindingDB Entry DOI: 10.7270/Q2BP02MH |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50261869
(CHEMBL467971 | N-[5-(4-Methoxyphenyl)pyridin-2-yl]...)Show InChI InChI=1S/C19H16N2O2/c1-23-17-10-7-14(8-11-17)16-9-12-18(20-13-16)21-19(22)15-5-3-2-4-6-15/h2-13H,1H3,(H,20,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research
Curated by ChEMBL
| Assay Description Inhibition of firefly luciferase activity |
J Med Chem 51: 4724-9 (2008)
Article DOI: 10.1021/jm8004509 BindingDB Entry DOI: 10.7270/Q2BP02MH |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50261868
(CHEMBL512625 | N-[5-(4-Chorophenyl)pyridin-2-yl]be...)Show InChI InChI=1S/C18H13ClN2O/c19-16-9-6-13(7-10-16)15-8-11-17(20-12-15)21-18(22)14-4-2-1-3-5-14/h1-12H,(H,20,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research
Curated by ChEMBL
| Assay Description Inhibition of firefly luciferase activity |
J Med Chem 51: 4724-9 (2008)
Article DOI: 10.1021/jm8004509 BindingDB Entry DOI: 10.7270/Q2BP02MH |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50238208
(2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | ...)Show InChI InChI=1S/C15H16N2O3/c1-10-4-7-14(16-9-10)17-15(18)12-6-5-11(19-2)8-13(12)20-3/h4-9H,1-3H3,(H,16,17,18) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research
Curated by ChEMBL
| Assay Description Inhibition of firefly luciferase activity |
J Med Chem 51: 4724-9 (2008)
Article DOI: 10.1021/jm8004509 BindingDB Entry DOI: 10.7270/Q2BP02MH |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50352639
(CHEMBL1719232)Show InChI InChI=1S/C18H23N3O2S/c1-12(2)23-15-5-3-4-14(10-15)16-11-20-18(24-16)21-8-6-13(7-9-21)17(19)22/h3-5,10-13H,6-9H2,1-2H3,(H2,19,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of fire fly luciferase |
J Med Chem 54: 6215-33 (2011)
Article DOI: 10.1021/jm200497t BindingDB Entry DOI: 10.7270/Q22F7NVF |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50272833
(4-Amino-N-(5-phenylpyridin-2-yl)benzamide | CHEMBL...)Show InChI InChI=1S/C18H15N3O/c19-16-9-6-14(7-10-16)18(22)21-17-11-8-15(12-20-17)13-4-2-1-3-5-13/h1-12H,19H2,(H,20,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research
Curated by ChEMBL
| Assay Description Inhibition of firefly luciferase activity |
J Med Chem 51: 4724-9 (2008)
Article DOI: 10.1021/jm8004509 BindingDB Entry DOI: 10.7270/Q2BP02MH |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50352634
(CHEMBL1699500)Show InChI InChI=1S/C15H15BrN2O2S/c16-12-3-1-10(2-4-12)13-9-21-15(17-13)18-7-5-11(6-8-18)14(19)20/h1-4,9,11H,5-8H2,(H,19,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of fire fly luciferase |
J Med Chem 54: 6215-33 (2011)
Article DOI: 10.1021/jm200497t BindingDB Entry DOI: 10.7270/Q22F7NVF |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50261810
(CHEMBL510929 | N-quinolin-2-yl benzamide)Show InChI InChI=1S/C16H12N2O/c19-16(13-7-2-1-3-8-13)18-15-11-10-12-6-4-5-9-14(12)17-15/h1-11H,(H,17,18,19) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research
Curated by ChEMBL
| Assay Description Inhibition of firefly luciferase activity |
J Med Chem 51: 4724-9 (2008)
Article DOI: 10.1021/jm8004509 BindingDB Entry DOI: 10.7270/Q2BP02MH |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50261867
(CHEMBL505491 | N-(5-Phenylpyridin-2-yl)cyclohexane...)Show InChI InChI=1S/C18H20N2O/c21-18(15-9-5-2-6-10-15)20-17-12-11-16(13-19-17)14-7-3-1-4-8-14/h1,3-4,7-8,11-13,15H,2,5-6,9-10H2,(H,19,20,21) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research
Curated by ChEMBL
| Assay Description Inhibition of firefly luciferase activity |
J Med Chem 51: 4724-9 (2008)
Article DOI: 10.1021/jm8004509 BindingDB Entry DOI: 10.7270/Q2BP02MH |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50352636
(CHEMBL1721157)Show InChI InChI=1S/C18H21N3O3S/c19-17(22)12-4-6-21(7-5-12)18-20-11-16(25-18)13-2-3-14-15(10-13)24-9-1-8-23-14/h2-3,10-12H,1,4-9H2,(H2,19,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of fire fly luciferase |
J Med Chem 54: 6215-33 (2011)
Article DOI: 10.1021/jm200497t BindingDB Entry DOI: 10.7270/Q22F7NVF |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50352637
(CHEMBL1704063)Show InChI InChI=1S/C17H20N4O3S/c18-15(22)11-4-6-21(7-5-11)17-20-19-16(25-17)12-2-3-13-14(10-12)24-9-1-8-23-13/h2-3,10-11H,1,4-9H2,(H2,18,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of fire fly luciferase |
J Med Chem 54: 6215-33 (2011)
Article DOI: 10.1021/jm200497t BindingDB Entry DOI: 10.7270/Q22F7NVF |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50352642
(CHEMBL1709231)Show SMILES O=C(Nc1ccccc1)C1CCN(CC1)c1ncc(s1)-c1ccc2OCCCOc2c1 Show InChI InChI=1S/C24H25N3O3S/c28-23(26-19-5-2-1-3-6-19)17-9-11-27(12-10-17)24-25-16-22(31-24)18-7-8-20-21(15-18)30-14-4-13-29-20/h1-3,5-8,15-17H,4,9-14H2,(H,26,28) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of fire fly luciferase |
J Med Chem 54: 6215-33 (2011)
Article DOI: 10.1021/jm200497t BindingDB Entry DOI: 10.7270/Q22F7NVF |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50352638
(CHEMBL1726915)Show InChI InChI=1S/C16H19N3OS/c1-11-2-4-12(5-3-11)14-10-18-16(21-14)19-8-6-13(7-9-19)15(17)20/h2-5,10,13H,6-9H2,1H3,(H2,17,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of fire fly luciferase |
J Med Chem 54: 6215-33 (2011)
Article DOI: 10.1021/jm200497t BindingDB Entry DOI: 10.7270/Q22F7NVF |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50261812
(CHEMBL459844 | N-(5-Methylpyridin-2-yl)benzamide)Show InChI InChI=1S/C13H12N2O/c1-10-7-8-12(14-9-10)15-13(16)11-5-3-2-4-6-11/h2-9H,1H3,(H,14,15,16) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research
Curated by ChEMBL
| Assay Description Inhibition of firefly luciferase activity |
J Med Chem 51: 4724-9 (2008)
Article DOI: 10.1021/jm8004509 BindingDB Entry DOI: 10.7270/Q2BP02MH |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50352635
(CHEMBL1720902)Show SMILES CC(C)Oc1cccc(c1)-c1ccnc(n1)N1CCC(CC1)C(N)=O Show InChI InChI=1S/C19H24N4O2/c1-13(2)25-16-5-3-4-15(12-16)17-6-9-21-19(22-17)23-10-7-14(8-11-23)18(20)24/h3-6,9,12-14H,7-8,10-11H2,1-2H3,(H2,20,24) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of fire fly luciferase |
J Med Chem 54: 6215-33 (2011)
Article DOI: 10.1021/jm200497t BindingDB Entry DOI: 10.7270/Q22F7NVF |
More data for this Ligand-Target Pair | |
Luciferin 4-monooxygenase
(Luciola lateralis) | BDBM50352640
(CHEMBL1712678)Show InChI InChI=1S/C16H19N3OS2/c1-21-13-4-2-11(3-5-13)14-10-18-16(22-14)19-8-6-12(7-9-19)15(17)20/h2-5,10,12H,6-9H2,1H3,(H2,17,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute
Curated by ChEMBL
| Assay Description Inhibition of fire fly luciferase |
J Med Chem 54: 6215-33 (2011)
Article DOI: 10.1021/jm200497t BindingDB Entry DOI: 10.7270/Q22F7NVF |
More data for this Ligand-Target Pair | |