BindingDB PrimarySearch

Found 5 hits of ec50 for UniProtKB: P22459
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 4 (Homo sapiens (Human))	BDBM50375408 (CHEMBL259345) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of Kv1.4 channel inactivation expressed in xenopus oocytes by voltage clamp assay				Bioorg Med Chem 16: 3067-75 (2008) Article DOI: 10.1016/j.bmc.2007.12.031 BindingDB Entry DOI: 10.7270/Q2M04697
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 4 (Homo sapiens (Human))	BDBM50375409 (CHEMBL408488) Show SMILES CC1(C)OCC(Br)(CO1)[N+]([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of Kv1.4 channel inactivation expressed in xenopus oocytes by voltage clamp assay				Bioorg Med Chem 16: 3067-75 (2008) Article DOI: 10.1016/j.bmc.2007.12.031 BindingDB Entry DOI: 10.7270/Q2M04697
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 4 (Homo sapiens (Human))	BDBM50182585 (5-acetyl-7-(4'-bromo)benzyloxy-6-hydroxy-4-methoxy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of Kv1.4 channel				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 4 (Homo sapiens (Human))	BDBM50182587 (5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of Kv1.4 channel				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 4 (Homo sapiens (Human))	BDBM50182597 (5-acetyl-4,7-benzyloxy-6-hydroxybenzofuran \| CHEMB...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of Kv1.4 channel				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair