Found 13 hits of ic50 for UniProtKB: P00883 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50380323
(CHEMBL2017785)Show SMILES CO[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O |r| Show InChI InChI=1S/C7H18O12P2/c1-17-5(3-19-21(14,15)16)7(10)6(9)4(8)2-18-20(11,12)13/h4-10H,2-3H2,1H3,(H2,11,12,13)(H2,14,15,16)/t4-,5-,6-,7-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle FBA assessed as inhibition of FBP cleavage by spectrophotometry |
ACS Med Chem Lett 2: 804-808 (2011)
Article DOI: 10.1021/ml200129s
BindingDB Entry DOI: 10.7270/Q28S4QXB |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50380322
(CHEMBL258208)Show SMILES O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O |r| Show InChI InChI=1S/C6H16O12P2/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16/h3-10H,1-2H2,(H2,11,12,13)(H2,14,15,16)/t3-,4-,5-,6-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| DrugBank
MMDB
PDB
Article
PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle FBA assessed as inhibition of FBP cleavage by spectrophotometry |
ACS Med Chem Lett 2: 804-808 (2011)
Article DOI: 10.1021/ml200129s
BindingDB Entry DOI: 10.7270/Q28S4QXB |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50330437
(1,6-di-O-phosphono-D-fructose | 2,3,4-trihydroxy-5...)Show SMILES OC(COP(O)(O)=O)[C@@H](O)C(=O)[C@H](O)COP(O)(O)=O |r| Show InChI InChI=1S/C6H14O12P2/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16/h3-5,7-9H,1-2H2,(H2,11,12,13)(H2,14,15,16)/t3?,4-,5-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle FBA assessed as inhibition of FBP cleavage by spectrophotometry |
ACS Med Chem Lett 2: 804-808 (2011)
Article DOI: 10.1021/ml200129s
BindingDB Entry DOI: 10.7270/Q28S4QXB |
More data for this
Ligand-Target Pair | |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50380328
(CHEMBL2017790)Show SMILES CCCCC[C@@](O)(COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O |r| Show InChI InChI=1S/C11H26O12P2/c1-2-3-4-5-11(15,7-23-25(19,20)21)10(14)9(13)8(12)6-22-24(16,17)18/h8-10,12-15H,2-7H2,1H3,(H2,16,17,18)(H2,19,20,21)/t8-,9-,10+,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle FBA assessed as inhibition of FBP cleavage by spectrophotometry |
ACS Med Chem Lett 2: 804-808 (2011)
Article DOI: 10.1021/ml200129s
BindingDB Entry DOI: 10.7270/Q28S4QXB |
More data for this
Ligand-Target Pair | |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50380326
(CHEMBL2017788)Show SMILES O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H](COP(O)(O)=O)OCCCc1ccccc1 |r| Show InChI InChI=1S/C15H26O12P2/c16-12(9-26-28(19,20)21)14(17)15(18)13(10-27-29(22,23)24)25-8-4-7-11-5-2-1-3-6-11/h1-3,5-6,12-18H,4,7-10H2,(H2,19,20,21)(H2,22,23,24)/t12-,13-,14-,15-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle FBA assessed as inhibition of FBP cleavage by spectrophotometry |
ACS Med Chem Lett 2: 804-808 (2011)
Article DOI: 10.1021/ml200129s
BindingDB Entry DOI: 10.7270/Q28S4QXB |
More data for this
Ligand-Target Pair | |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50380324
(CHEMBL2017786)Show SMILES CCO[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O |r| Show InChI InChI=1S/C8H20O12P2/c1-2-18-6(4-20-22(15,16)17)8(11)7(10)5(9)3-19-21(12,13)14/h5-11H,2-4H2,1H3,(H2,12,13,14)(H2,15,16,17)/t5-,6-,7-,8-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle FBA assessed as inhibition of FBP cleavage by spectrophotometry |
ACS Med Chem Lett 2: 804-808 (2011)
Article DOI: 10.1021/ml200129s
BindingDB Entry DOI: 10.7270/Q28S4QXB |
More data for this
Ligand-Target Pair | |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50320385
((4aR,6aR,12bS)-4,4,6a,12b-Tetramethyl-1,4a,5,6,6a,...)Show SMILES C[C@@]12CC[C@H]3C(C)(C)C(=O)CC[C@]3(C)C1Cc1cc3ccccc3n21 |r| Show InChI InChI=1S/C23H29NO/c1-21(2)18-9-12-23(4)19(22(18,3)11-10-20(21)25)14-16-13-15-7-5-6-8-17(15)24(16)23/h5-8,13,18-19H,9-12,14H2,1-4H3/t18-,19?,22-,23+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Yaound£ I
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle aldolase |
Bioorg Med Chem Lett 20: 3495-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.145
BindingDB Entry DOI: 10.7270/Q2HH6K8B |
More data for this
Ligand-Target Pair | |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50330433
(4-{hydroxy[(phosphonooxy)acetyl]amino}butyl dihydr...)Show InChI InChI=1S/C6H15NO10P2/c8-6(5-17-19(13,14)15)7(9)3-1-2-4-16-18(10,11)12/h9H,1-5H2,(H2,10,11,12)(H2,13,14,15) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ Paris-Sud
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle zinc dependent class 1 Fba expressed in Escherichia coli |
J Med Chem 53: 7836-42 (2010)
Article DOI: 10.1021/jm1009814
BindingDB Entry DOI: 10.7270/Q2MG7PQC |
More data for this
Ligand-Target Pair | |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50380329
(CHEMBL2017791)Show SMILES O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@](O)(CCCc1ccccc1)COP(O)(O)=O |r| Show InChI InChI=1S/C15H26O12P2/c16-12(9-26-28(20,21)22)13(17)14(18)15(19,10-27-29(23,24)25)8-4-7-11-5-2-1-3-6-11/h1-3,5-6,12-14,16-19H,4,7-10H2,(H2,20,21,22)(H2,23,24,25)/t12-,13-,14+,15-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.37E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle FBA assessed as inhibition of FBP cleavage by spectrophotometry |
ACS Med Chem Lett 2: 804-808 (2011)
Article DOI: 10.1021/ml200129s
BindingDB Entry DOI: 10.7270/Q28S4QXB |
More data for this
Ligand-Target Pair | |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50320386
(3-O-acetylgreenwayodendrin | CHEMBL1083629)Show SMILES CC(=O)O[C@H]1CC[C@]2(C)[C@H]3Cc4cc5ccccc5n4[C@]3(C)CC[C@H]2C1(C)C |r| Show InChI InChI=1S/C25H33NO2/c1-16(27)28-22-11-12-24(4)20(23(22,2)3)10-13-25(5)21(24)15-18-14-17-8-6-7-9-19(17)26(18)25/h6-9,14,20-22H,10-13,15H2,1-5H3/t20-,21+,22-,24-,25+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Yaound£ I
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle aldolase |
Bioorg Med Chem Lett 20: 3495-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.145
BindingDB Entry DOI: 10.7270/Q2HH6K8B |
More data for this
Ligand-Target Pair | |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50380325
(CHEMBL2017787)Show SMILES CCCCCO[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O |r| Show InChI InChI=1S/C11H26O12P2/c1-2-3-4-5-21-9(7-23-25(18,19)20)11(14)10(13)8(12)6-22-24(15,16)17/h8-14H,2-7H2,1H3,(H2,15,16,17)(H2,18,19,20)/t8-,9-,10-,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.57E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle FBA assessed as inhibition of FBP cleavage by spectrophotometry |
ACS Med Chem Lett 2: 804-808 (2011)
Article DOI: 10.1021/ml200129s
BindingDB Entry DOI: 10.7270/Q28S4QXB |
More data for this
Ligand-Target Pair | |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50380327
(CHEMBL2017789)Show SMILES CC[C@@](O)(COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O |r| Show InChI InChI=1S/C8H20O12P2/c1-2-8(12,4-20-22(16,17)18)7(11)6(10)5(9)3-19-21(13,14)15/h5-7,9-12H,2-4H2,1H3,(H2,13,14,15)(H2,16,17,18)/t5-,6-,7+,8-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.44E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle FBA assessed as inhibition of FBP cleavage by spectrophotometry |
ACS Med Chem Lett 2: 804-808 (2011)
Article DOI: 10.1021/ml200129s
BindingDB Entry DOI: 10.7270/Q28S4QXB |
More data for this
Ligand-Target Pair | |
Fructose-bisphosphate aldolase A
(Oryctolagus cuniculus) | BDBM50320387
(CHEMBL1086376 | polyveoline)Show SMILES C[C@@]12CC[C@H]3C(C)(C)[C@H](O)CC[C@]3(C)[C@@H]1C[C@@H]1Nc3ccccc3[C@H]21 |r| Show InChI InChI=1S/C23H33NO/c1-21(2)17-9-11-23(4)18(22(17,3)12-10-19(21)25)13-16-20(23)14-7-5-6-8-15(14)24-16/h5-8,16-20,24-25H,9-13H2,1-4H3/t16-,17-,18-,19+,20-,22-,23+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Yaound£ I
Curated by ChEMBL
| Assay Description
Inhibition of rabbit muscle aldolase |
Bioorg Med Chem Lett 20: 3495-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.145
BindingDB Entry DOI: 10.7270/Q2HH6K8B |
More data for this
Ligand-Target Pair | |
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