Compile Data Set for Download or QSAR

Found 14 hits of ic50 for UniProtKB: P17865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Bacillus subtilis)	BDBM50392993 (TOTAROL) Show SMILES CC(C)c1c(O)ccc2c1CC[C@H]1C(C)(C)CCC[C@]21C |r| Show InChI InChI=1S/C20H30O/c1-13(2)18-14-7-10-17-19(3,4)11-6-12-20(17,5)15(14)8-9-16(18)21/h8-9,13,17,21H,6-7,10-12H2,1-5H3/t17-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity by enzyme-coupled assay				ACS Med Chem Lett 3: 818-822 (2012) Article DOI: 10.1021/ml3001775 BindingDB Entry DOI: 10.7270/Q2XG9S7W
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50067040 (((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...) Show SMILES COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O |w:12.11,5.4| Show InChI InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ polymerization				Eur J Med Chem 45: 4209-14 (2010) Article DOI: 10.1016/j.ejmech.2010.06.015 BindingDB Entry DOI: 10.7270/Q28G8KWN
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50085934 (CHEMBL3425686) Show SMILES CN(C)CCNc1nc(nc2ccc(C)cc12)-c1ccc2ccccc2c1 Show InChI InChI=1S/C23H24N4/c1-16-8-11-21-20(14-16)23(24-12-13-27(2)3)26-22(25-21)19-10-9-17-6-4-5-7-18(17)15-19/h4-11,14-15H,12-13H2,1-3H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50085935 (CHEMBL3425685) Show SMILES COc1ccc(cc1)-c1nc(NCCN(C)C)c2cc(C)ccc2n1 Show InChI InChI=1S/C20H24N4O/c1-14-5-10-18-17(13-14)20(21-11-12-24(2)3)23-19(22-18)15-6-8-16(25-4)9-7-15/h5-10,13H,11-12H2,1-4H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50085936 (CHEMBL3425684) Show SMILES CN(C)CCNc1nc(nc2ccc(C)cc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H21ClN4/c1-13-4-9-17-16(12-13)19(21-10-11-24(2)3)23-18(22-17)14-5-7-15(20)8-6-14/h4-9,12H,10-11H2,1-3H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50085937 (CHEMBL3425683) Show SMILES CN(C)CCNc1nc(N)nc2ccc(C)cc12 Show InChI InChI=1S/C13H19N5/c1-9-4-5-11-10(8-9)12(17-13(14)16-11)15-6-7-18(2)3/h4-5,8H,6-7H2,1-3H3,(H3,14,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50086040 (CHEMBL3425681) Show SMILES CN(C)CCNc1nc(NCc2ccccc2)nc2ccc(C)cc12 Show InChI InChI=1S/C20H25N5/c1-15-9-10-18-17(13-15)19(21-11-12-25(2)3)24-20(23-18)22-14-16-7-5-4-6-8-16/h4-10,13H,11-12,14H2,1-3H3,(H2,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50086041 (CHEMBL3425680) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(I)cc2)nc2ccc(C)cc12 Show InChI InChI=1S/C21H23IN4/c1-15-4-10-19-18(14-15)21(23-12-13-26(2)3)25-20(24-19)11-7-16-5-8-17(22)9-6-16/h4-11,14H,12-13H2,1-3H3,(H,23,24,25)/b11-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50086043 (CHEMBL3425679) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Br)cc2)nc2ccc(C)cc12 Show InChI InChI=1S/C21H23BrN4/c1-15-4-10-19-18(14-15)21(23-12-13-26(2)3)25-20(24-19)11-7-16-5-8-17(22)9-6-16/h4-11,14H,12-13H2,1-3H3,(H,23,24,25)/b11-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50086044 (CHEMBL3425678) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(cc2)C(C)(C)C)nc2ccc(C)cc12 Show InChI InChI=1S/C25H32N4/c1-18-7-13-22-21(17-18)24(26-15-16-29(5)6)28-23(27-22)14-10-19-8-11-20(12-9-19)25(2,3)4/h7-14,17H,15-16H2,1-6H3,(H,26,27,28)/b14-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50086048 (CHEMBL3425616) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(cc2)C(F)(F)F)nc2ccc(C)cc12 Show InChI InChI=1S/C22H23F3N4/c1-15-4-10-19-18(14-15)21(26-12-13-29(2)3)28-20(27-19)11-7-16-5-8-17(9-6-16)22(23,24)25/h4-11,14H,12-13H2,1-3H3,(H,26,27,28)/b11-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50085932 (CHEMBL3425687) Show SMILES CN(C)CCNc1nc(nc2ccc(C)cc12)-c1cc2ccccc2o1 Show InChI InChI=1S/C21H22N4O/c1-14-8-9-17-16(12-14)20(22-10-11-25(2)3)24-21(23-17)19-13-15-6-4-5-7-18(15)26-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50085931 (CHEMBL3425688) Show SMILES CN(C)CCNc1nc(nc2ccc(C)cc12)-c1cccs1 Show InChI InChI=1S/C17H20N4S/c1-12-6-7-14-13(11-12)16(18-8-9-21(2)3)20-17(19-14)15-5-4-10-22-15/h4-7,10-11H,8-9H2,1-3H3,(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Bacillus subtilis)	BDBM50085995 (CHEMBL3425682) Show SMILES CN(C)CCNc1nc(NCc2ccc(Cl)cc2)nc2ccc(C)cc12 Show InChI InChI=1S/C20H24ClN5/c1-14-4-9-18-17(12-14)19(22-10-11-26(2)3)25-20(24-18)23-13-15-5-7-16(21)8-6-15/h4-9,12H,10-11,13H2,1-3H3,(H2,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair