Found 8 hits of ki for UniProtKB: P53686 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
NAD-dependent protein deacetylase HST2
(Saccharomyces cerevisiae) | BDBM50304357
(4-(4-ethylphenoxy)-butyric acid 6-oxo-6H-benzo[c]c...)Show SMILES CCc1ccc(OCCCC(O)Oc2ccc3c(c2)oc(=O)c2ccccc32)cc1 Show InChI InChI=1S/C25H24O5/c1-2-17-9-11-18(12-10-17)28-15-5-8-24(26)29-19-13-14-21-20-6-3-4-7-22(20)25(27)30-23(21)16-19/h3-4,6-7,9-14,16,24,26H,2,5,8,15H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute
Curated by ChEMBL
| Assay Description
Noncompetitive inhibition of yeast Hst2 using NAD+ substrate |
Bioorg Med Chem 17: 7031-41 (2009)
Article DOI: 10.1016/j.bmc.2009.07.073
BindingDB Entry DOI: 10.7270/Q21V5FWG |
More data for this
Ligand-Target Pair | |
NAD-dependent protein deacetylase HST2
(Saccharomyces cerevisiae) | BDBM50304355
(3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methyl...)Show InChI InChI=1S/C14H9Cl5O2/c1-5-2-9(16)13(20)6(11(5)18)3-7-12(19)8(15)4-10(17)14(7)21/h2,4,20-21H,3H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute
Curated by ChEMBL
| Assay Description
Mixed inhibition of yeast Hst2 using Acetyl-lysine substrate |
Bioorg Med Chem 17: 7031-41 (2009)
Article DOI: 10.1016/j.bmc.2009.07.073
BindingDB Entry DOI: 10.7270/Q21V5FWG |
More data for this
Ligand-Target Pair | |
NAD-dependent protein deacetylase HST2
(Saccharomyces cerevisiae) | BDBM50304355
(3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methyl...)Show InChI InChI=1S/C14H9Cl5O2/c1-5-2-9(16)13(20)6(11(5)18)3-7-12(19)8(15)4-10(17)14(7)21/h2,4,20-21H,3H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute
Curated by ChEMBL
| Assay Description
Noncompetitive inhibition of yeast Hst2 using NAD+ substrate |
Bioorg Med Chem 17: 7031-41 (2009)
Article DOI: 10.1016/j.bmc.2009.07.073
BindingDB Entry DOI: 10.7270/Q21V5FWG |
More data for this
Ligand-Target Pair | |
NAD-dependent protein deacetylase HST2
(Saccharomyces cerevisiae) | BDBM50304357
(4-(4-ethylphenoxy)-butyric acid 6-oxo-6H-benzo[c]c...)Show SMILES CCc1ccc(OCCCC(O)Oc2ccc3c(c2)oc(=O)c2ccccc32)cc1 Show InChI InChI=1S/C25H24O5/c1-2-17-9-11-18(12-10-17)28-15-5-8-24(26)29-19-13-14-21-20-6-3-4-7-22(20)25(27)30-23(21)16-19/h3-4,6-7,9-14,16,24,26H,2,5,8,15H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute
Curated by ChEMBL
| Assay Description
Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrate |
Bioorg Med Chem 17: 7031-41 (2009)
Article DOI: 10.1016/j.bmc.2009.07.073
BindingDB Entry DOI: 10.7270/Q21V5FWG |
More data for this
Ligand-Target Pair | |
NAD-dependent protein deacetylase HST2
(Saccharomyces cerevisiae) | BDBM50304354
(3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...)Show InChI InChI=1S/C11H11NO3/c13-10(14)5-6-12-7-8-3-1-2-4-9(8)11(12)15/h1-4H,5-7H2,(H,13,14) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute
Curated by ChEMBL
| Assay Description
Noncompetitive inhibition of yeast Hst2 using NAD+ substrate |
Bioorg Med Chem 17: 7031-41 (2009)
Article DOI: 10.1016/j.bmc.2009.07.073
BindingDB Entry DOI: 10.7270/Q21V5FWG |
More data for this
Ligand-Target Pair | |
NAD-dependent protein deacetylase HST2
(Saccharomyces cerevisiae) | BDBM50304354
(3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...)Show InChI InChI=1S/C11H11NO3/c13-10(14)5-6-12-7-8-3-1-2-4-9(8)11(12)15/h1-4H,5-7H2,(H,13,14) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute
Curated by ChEMBL
| Assay Description
Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrate |
Bioorg Med Chem 17: 7031-41 (2009)
Article DOI: 10.1016/j.bmc.2009.07.073
BindingDB Entry DOI: 10.7270/Q21V5FWG |
More data for this
Ligand-Target Pair | |
NAD-dependent protein deacetylase HST2
(Saccharomyces cerevisiae) | BDBM50304351
(6-methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3...)Show InChI InChI=1S/C15H19NO3/c1-16-7-6-11-9-15(19-3)14(17)10-12(11)13(16)5-4-8-18-2/h9-10,13,17H,6-8H2,1-3H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute
Curated by ChEMBL
| Assay Description
Mixed inhibition of yeast Hst2 using NAD+ substrate |
Bioorg Med Chem 17: 7031-41 (2009)
Article DOI: 10.1016/j.bmc.2009.07.073
BindingDB Entry DOI: 10.7270/Q21V5FWG |
More data for this
Ligand-Target Pair | |
NAD-dependent protein deacetylase HST2
(Saccharomyces cerevisiae) | BDBM50304351
(6-methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3...)Show InChI InChI=1S/C15H19NO3/c1-16-7-6-11-9-15(19-3)14(17)10-12(11)13(16)5-4-8-18-2/h9-10,13,17H,6-8H2,1-3H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute
Curated by ChEMBL
| Assay Description
Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrate |
Bioorg Med Chem 17: 7031-41 (2009)
Article DOI: 10.1016/j.bmc.2009.07.073
BindingDB Entry DOI: 10.7270/Q21V5FWG |
More data for this
Ligand-Target Pair | |
Search and Browse
