Compile Data Set for Download or QSAR

Found 13 hits of ic50 for UniProtKB: P00639   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Deoxyribonuclease-1 (Bos taurus)	BDBM50356642 (CHEMBL1917196) Show SMILES CCCCCCCCCCCC(=O)Oc1cccc2C(=O)C=CC(=O)c12 |c:21| Show InChI InChI=1S/C22H28O4/c1-2-3-4-5-6-7-8-9-10-14-21(25)26-20-13-11-12-17-18(23)15-16-19(24)22(17)20/h11-13,15-16H,2-10,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University Curated by ChEMBL					Assay Description Inhibition of bovine deoxyribonuclease I by agarose gel electrophoresis				Bioorg Med Chem 19: 5803-12 (2011) Article DOI: 10.1016/j.bmc.2011.08.023 BindingDB Entry DOI: 10.7270/Q2DZ0989
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50356643 (CHEMBL1917198) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)Oc1cccc2C(=O)C=CC(=O)c12 |c:27| Show InChI InChI=1S/C28H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-27(31)32-26-19-17-18-23-24(29)21-22-25(30)28(23)26/h9-10,17-19,21-22H,2-8,11-16,20H2,1H3/b10-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University Curated by ChEMBL					Assay Description Inhibition of bovine deoxyribonuclease I by agarose gel electrophoresis				Bioorg Med Chem 19: 5803-12 (2011) Article DOI: 10.1016/j.bmc.2011.08.023 BindingDB Entry DOI: 10.7270/Q2DZ0989
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50448689 (CHEMBL3127730) Show SMILES CCCC[C@@H](O)\C=C(/C)\C=C\C=C/C(=O)N1CCCC1=O |r| Show InChI InChI=1S/C17H25NO3/c1-3-4-9-15(19)13-14(2)8-5-6-10-16(20)18-12-7-11-17(18)21/h5-6,8,10,13,15,19H,3-4,7,9,11-12H2,1-2H3/b8-5+,10-6-,14-13+/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of bovine deoxyribonuclease 1 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50379294 (CHEMBL2011647) Show SMILES Cc1cc(O)cc(O)c1C(=O)O[C@H]1[C@@H]2COC(\C=C\CO)=CC2=CC(=O)[C@@]1(C)O |r,c:21,24| Show InChI InChI=1S/C21H22O8/c1-11-6-13(23)9-16(24)18(11)20(26)29-19-15-10-28-14(4-3-5-22)7-12(15)8-17(25)21(19,2)27/h3-4,6-9,15,19,22-24,27H,5,10H2,1-2H3/b4-3+/t15-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Science University of Tokyo Curated by ChEMBL					Assay Description Inhibition of bovine deoxyribonuclease 1 using [3H]-labelled DNA after 30 mins by agorose gel electrophoresis				J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50379292 (CHEMBL2011646) Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(OC(=O)c3c(C)cc(O)cc3O)[C@@H](O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,19(25)15(12)10-27-14)28-20(26)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,25H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Science University of Tokyo Curated by ChEMBL					Assay Description Inhibition of bovine deoxyribonuclease 1 using [3H]-labelled DNA after 30 mins by agorose gel electrophoresis				J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM22984 ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) Show SMILES COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO |r| Show InChI InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of bovine pancreas DNase 1 assessed as undigested supercoiled pBR322 DNA concentration				J Nat Prod 64: 204-7 (2001) BindingDB Entry DOI: 10.7270/Q2W37W21
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50448691 (CHEMBL3127729) Show SMILES C\C(\C=C\CCC(=O)N1CCCC1=O)=C/C1CCCCO1 Show InChI InChI=1S/C17H25NO3/c1-14(13-15-8-4-5-12-21-15)7-2-3-9-16(19)18-11-6-10-17(18)20/h2,7,13,15H,3-6,8-12H2,1H3/b7-2+,14-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of bovine deoxyribonuclease 1 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50448690 (CHEMBL3127728) Show SMILES CCCCC(=O)C=C(C)C=CCCC(=O)N1CCCC1=O |w:6.5,9.8| Show InChI InChI=1S/C17H25NO3/c1-3-4-9-15(19)13-14(2)8-5-6-10-16(20)18-12-7-11-17(18)21/h5,8,13H,3-4,6-7,9-12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of bovine deoxyribonuclease 1 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50448688 (Pecilocin | Variotin) Show SMILES CCCC[C@@H](O)\C=C(/C)\C=C\C=C\C(=O)N1CCCC1=O |r| Show InChI InChI=1S/C17H25NO3/c1-3-4-9-15(19)13-14(2)8-5-6-10-16(20)18-12-7-11-17(18)21/h5-6,8,10,13,15,19H,3-4,7,9,11-12H2,1-2H3/b8-5+,10-6+,14-13+/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of bovine deoxyribonuclease 1 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50379293 (CHEMBL2011648) Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1 |r,t:3,5| Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Science University of Tokyo Curated by ChEMBL					Assay Description Inhibition of bovine deoxyribonuclease 1 using [3H]-labelled DNA after 30 mins by agorose gel electrophoresis				J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50242374 (CHEMBL505529 | topostatin) Show SMILES CCCCCCCC(C)CC=C(C)C=CC(=O)C(C)CCC1OC(=O)[C@H](CC(OS(O)(=O)=O)C(N)=O)NC(=O)[C@@H](C)CNC(=O)C(=C)NC(=O)C1C |r,w:14.14,10.9| Show InChI InChI=1S/C36H58N4O11S/c1-8-9-10-11-12-13-22(2)14-15-23(3)16-18-29(41)24(4)17-19-30-26(6)34(44)39-27(7)35(45)38-21-25(5)33(43)40-28(36(46)50-30)20-31(32(37)42)51-52(47,48)49/h15-16,18,22,24-26,28,30-31H,7-14,17,19-21H2,1-6H3,(H2,37,42)(H,38,45)(H,39,44)(H,40,43)(H,47,48,49)/t22?,24?,25-,26?,28-,30?,31?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of bovine pancreas DNase 1 assessed as undigested supercoiled pBR322 DNA concentration				J Nat Prod 64: 204-7 (2001) BindingDB Entry DOI: 10.7270/Q2W37W21
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50008923 ((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...) Show SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O |r| Show InChI InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of bovine pancreas DNase 1 assessed as undigested supercoiled pBR322 DNA concentration				J Nat Prod 64: 204-7 (2001) BindingDB Entry DOI: 10.7270/Q2W37W21
					More data for this Ligand-Target Pair
Deoxyribonuclease-1 (Bos taurus)	BDBM50164888 (6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene...) Show SMILES Oc1ccc(\C=C2\C(=O)Oc3cc(O)ccc23)cc1 Show InChI InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)7-13-12-6-5-11(17)8-14(12)19-15(13)18/h1-8,16-17H/b13-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of bovine pancreas DNase 1 assessed as undigested supercoiled pBR322 DNA concentration				J Nat Prod 64: 204-7 (2001) BindingDB Entry DOI: 10.7270/Q2W37W21
					More data for this Ligand-Target Pair