Compile Data Set for Download or QSAR

Found 9 hits of ic50 for UniProtKB: P19621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin [1-24] (Sus scrofa)	BDBM21641 (2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...) Show SMILES OC(=O)CNC(=O)C(CS)Cc1ccccc1 Show InChI InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica Curated by ChEMBL					Assay Description Inhibition of pig kidney NEP by fluorimetry				Bioorg Med Chem Lett 19: 4715-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT
					More data for this Ligand-Target Pair
Neprilysin [1-24] (Sus scrofa)	BDBM50046261 (2-(3-Mercapto-5-methyl-hexanoylamino)-3-phenyl-pro...) Show SMILES CC(C)CC(S)CC(=O)NC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H23NO3S/c1-11(2)8-13(21)10-15(18)17-14(16(19)20)9-12-6-4-3-5-7-12/h3-7,11,13-14,21H,8-10H2,1-2H3,(H,17,18)(H,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica Curated by ChEMBL					Assay Description Inhibition of pig kidney NEP by fluorimetry				Bioorg Med Chem Lett 19: 4715-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT
					More data for this Ligand-Target Pair
Neprilysin [1-24] (Sus scrofa)	BDBM50046258 (3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hex...) Show SMILES CC(C)CC(S)CC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C25H32N2O5S/c1-16(2)12-20(33)15-23(29)26-21(13-17-6-4-3-5-7-17)24(30)27-22(25(31)32)14-18-8-10-19(28)11-9-18/h3-11,16,20-22,28,33H,12-15H2,1-2H3,(H,26,29)(H,27,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica Curated by ChEMBL					Assay Description Inhibition of pig kidney NEP by fluorimetry				Bioorg Med Chem Lett 19: 4715-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT
					More data for this Ligand-Target Pair
Neprilysin [1-24] (Sus scrofa)	BDBM50298107 (3-(4-Hydroxy-phenyl)-2-(4,4,4-trifluoro-3-mercapto...) Show SMILES OC(=O)C(Cc1ccc(O)cc1)NC(=O)CC(S)C(F)(F)F Show InChI InChI=1S/C13H14F3NO4S/c14-13(15,16)10(22)6-11(19)17-9(12(20)21)5-7-1-3-8(18)4-2-7/h1-4,9-10,18,22H,5-6H2,(H,17,19)(H,20,21)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica Curated by ChEMBL					Assay Description Inhibition of pig kidney NEP by fluorimetry				Bioorg Med Chem Lett 19: 4715-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT
					More data for this Ligand-Target Pair
Neprilysin [1-24] (Sus scrofa)	BDBM50298108 (3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-...) Show SMILES OC(=O)C(Cc1ccc(F)cc1)NC(=O)CC(S)C(F)(F)F Show InChI InChI=1S/C13H13F4NO3S/c14-8-3-1-7(2-4-8)5-9(12(20)21)18-11(19)6-10(22)13(15,16)17/h1-4,9-10,22H,5-6H2,(H,18,19)(H,20,21)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica Curated by ChEMBL					Assay Description Inhibition of pig kidney NEP by fluorimetry				Bioorg Med Chem Lett 19: 4715-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT
					More data for this Ligand-Target Pair
Neprilysin [1-24] (Sus scrofa)	BDBM50298106 (3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...) Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)CC(S)C(F)(F)F Show InChI InChI=1S/C13H14F3NO3S/c14-13(15,16)10(21)7-11(18)17-9(12(19)20)6-8-4-2-1-3-5-8/h1-5,9-10,21H,6-7H2,(H,17,18)(H,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica Curated by ChEMBL					Assay Description Inhibition of pig kidney NEP by fluorimetry				Bioorg Med Chem Lett 19: 4715-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT
					More data for this Ligand-Target Pair
Neprilysin [1-24] (Sus scrofa)	BDBM50298111 (3-(4-Hydroxy-phenyl)-2-[3-phenyl-2-(4,4,4-trifluor...) Show SMILES OC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)NC(=O)CC(S)C(F)(F)F Show InChI InChI=1S/C22H23F3N2O5S/c23-22(24,25)18(33)12-19(29)26-16(10-13-4-2-1-3-5-13)20(30)27-17(21(31)32)11-14-6-8-15(28)9-7-14/h1-9,16-18,28,33H,10-12H2,(H,26,29)(H,27,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica Curated by ChEMBL					Assay Description Inhibition of pig kidney NEP by fluorimetry				Bioorg Med Chem Lett 19: 4715-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT
					More data for this Ligand-Target Pair
Neprilysin [1-24] (Sus scrofa)	BDBM50298109 (3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...) Show SMILES OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CC(S)C(F)(F)F Show InChI InChI=1S/C15H15F3N2O3S/c16-15(17,18)12(24)6-13(21)20-11(14(22)23)5-8-7-19-10-4-2-1-3-9(8)10/h1-4,7,11-12,19,24H,5-6H2,(H,20,21)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica Curated by ChEMBL					Assay Description Inhibition of pig kidney NEP by fluorimetry				Bioorg Med Chem Lett 19: 4715-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT
					More data for this Ligand-Target Pair
Neprilysin [1-24] (Sus scrofa)	BDBM50298110 (2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino...) Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)CC(S)C(F)(F)C(F)(F)F Show InChI InChI=1S/C14H14F5NO3S/c15-13(16,14(17,18)19)10(24)7-11(21)20-9(12(22)23)6-8-4-2-1-3-5-8/h1-5,9-10,24H,6-7H2,(H,20,21)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica Curated by ChEMBL					Assay Description Inhibition of pig kidney NEP by fluorimetry				Bioorg Med Chem Lett 19: 4715-9 (2009) Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT
					More data for this Ligand-Target Pair