Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337101 ((S)-1-(2-(Naphthalen-2-ylcarbonyl)benzamido)ethane...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337094 ((S)-1-(2-Fluoro-6-phenylbenzamido)ethaneboronic ac...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337100 ((S)-1-(2-[(Phenylsulfonyl)amino]benzamido)ethanebo...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337095 ((S)-1-(2,6-Difluorobenzamido)ethaneboronic acid | ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385268 (CHEMBL2035292) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385267 (CHEMBL2035284) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337093 ((S)-1-(2-Phenylbenzamido)ethaneboronic acid | CHEM...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337092 ((S)-1-(2-Benzylbenzamido)ethaneboronic acid | CHEM...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337091 ((S)-1-(1-Benzothiophene-5-carboxamido)ethaneboroni...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337098 ((R)-1-(2,6-Difluorobenzamido)ethaneboronic acid | ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337096 ((S)-1-(2,6-Dichlorobenzamido)ethaneboronic acid | ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337099 ((R)-1-(2-Benzylbenzamido)ethaneboronic acid | CHEM...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337090 ((S)-1-(Naphthalene-2-carboxamido)ethaneboronic aci...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385266 (CHEMBL2035295) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300661 (3-borono-5-(2-methoxybenzamido)benzoic acid | CHEM...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300664 (3-borono-5-(2-phenoxyacetamido)benzoic acid | CHEM...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300662 (3-borono-5-(thiophene-2-carboxamido)benzoic acid |...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300660 (3-benzamido-5-boronobenzoic acid | CHEMBL575719) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385262 (CHEMBL2035285) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337097 ((S)-1-(2-(Propan-2-yl)benzamido)ethaneboronic acid...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300663 (3-borono-5-(2-(thiophen-2-yl)acetamido)benzoic aci...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385263 (CHEMBL2035289) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300659 (3-borono-5-(2-phenylacetamido)benzoic acid | CHEMB...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM39809 (Acylglycineboronic acid, 6) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50067893 (3-Carboxyphenylboronicacid | 3-boronobenzoic acid ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385270 (CHEMBL2035291) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair |