Found 54 hits of ic50 data for polymerid = 50006093 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601900
(CHEMBL5192614)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](C)B(O)O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601905
(CHEMBL5203212)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)C(F)(F)C(=O)NCC(O)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100890
(CHEMBL3325855)Show SMILES OC1Cc2c(O)cc3OC4(Oc5c(O)c(O)cc(O)c5C(C4O)c3c2OC1c1ccc(O)c(O)c1)c1ccc(O)c(O)c1 |THB:22:21:11.19.10:23.7.8| Show InChI InChI=1S/C30H24O13/c31-13-3-1-10(5-16(13)34)26-20(38)7-12-15(33)9-21-23(27(12)41-26)24-22-18(36)8-19(37)25(39)28(22)43-30(42-21,29(24)40)11-2-4-14(32)17(35)6-11/h1-6,8-9,20,24,26,29,31-40H,7H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100890
(CHEMBL3325855)Show SMILES OC1Cc2c(O)cc3OC4(Oc5c(O)c(O)cc(O)c5C(C4O)c3c2OC1c1ccc(O)c(O)c1)c1ccc(O)c(O)c1 |THB:22:21:11.19.10:23.7.8| Show InChI InChI=1S/C30H24O13/c31-13-3-1-10(5-16(13)34)26-20(38)7-12-15(33)9-21-23(27(12)41-26)24-22-18(36)8-19(37)25(39)28(22)43-30(42-21,29(24)40)11-2-4-14(32)17(35)6-11/h1-6,8-9,20,24,26,29,31-40H,7H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601898
(CHEMBL5188719)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H](NC(C)=O)C1CCCC1)C(=O)NCC(=O)NC(C)C(=O)C(=O)NCCC(O)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50045200
(CHEMBL3310712)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)C(F)(F)C(=O)NCC(O)=O |r| Show InChI InChI=1S/C28H47F2N7O10/c1-7-13(2)20(36-24(44)18(35-17(6)39)10-8-9-11-31)25(45)37-21(16(5)38)26(46)34-15(4)23(43)33-14(3)22(42)28(29,30)27(47)32-12-19(40)41/h13-16,18,20-21,38H,7-12,31H2,1-6H3,(H,32,47)(H,33,43)(H,34,46)(H,35,39)(H,36,44)(H,37,45)(H,40,41)/t13-,14-,15-,16+,18-,20-,21-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum serine protease subtilisin-like protease 1by fluorimetric assay |
Bioorg Med Chem Lett 24: 3582-6 (2014)
Article DOI: 10.1016/j.bmcl.2014.05.044
BindingDB Entry DOI: 10.7270/Q22Z175D |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50045201
(CHEMBL3310822)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)C(F)(F)C(=O)NCC(O)=O |r| Show InChI InChI=1S/C22H35F2N5O9/c1-7-9(2)15(28-13(6)31)19(36)29-16(12(5)30)20(37)27-11(4)18(35)26-10(3)17(34)22(23,24)21(38)25-8-14(32)33/h9-12,15-16,30H,7-8H2,1-6H3,(H,25,38)(H,26,35)(H,27,37)(H,28,31)(H,29,36)(H,32,33)/t9-,10-,11-,12+,15-,16-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum serine protease subtilisin-like protease 1by fluorimetric assay |
Bioorg Med Chem Lett 24: 3582-6 (2014)
Article DOI: 10.1016/j.bmcl.2014.05.044
BindingDB Entry DOI: 10.7270/Q22Z175D |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50045201
(CHEMBL3310822)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)C(F)(F)C(=O)NCC(O)=O |r| Show InChI InChI=1S/C22H35F2N5O9/c1-7-9(2)15(28-13(6)31)19(36)29-16(12(5)30)20(37)27-11(4)18(35)26-10(3)17(34)22(23,24)21(38)25-8-14(32)33/h9-12,15-16,30H,7-8H2,1-6H3,(H,25,38)(H,26,35)(H,27,37)(H,28,31)(H,29,36)(H,32,33)/t9-,10-,11-,12+,15-,16-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50045200
(CHEMBL3310712)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)C(F)(F)C(=O)NCC(O)=O |r| Show InChI InChI=1S/C28H47F2N7O10/c1-7-13(2)20(36-24(44)18(35-17(6)39)10-8-9-11-31)25(45)37-21(16(5)38)26(46)34-15(4)23(43)33-14(3)22(42)28(29,30)27(47)32-12-19(40)41/h13-16,18,20-21,38H,7-12,31H2,1-6H3,(H,32,47)(H,33,43)(H,34,46)(H,35,39)(H,36,44)(H,37,45)(H,40,41)/t13-,14-,15-,16+,18-,20-,21-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100879
(CHEMBL3326334)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NC(C)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C21H35N5O9/c1-6-10(2)16(25-13(5)28)20(34)26-17(12(4)27)19(33)23-9-14(29)24-11(3)18(32)21(35)22-8-7-15(30)31/h10-12,16-17,27H,6-9H2,1-5H3,(H,22,35)(H,23,33)(H,24,29)(H,25,28)(H,26,34)(H,30,31)/t10-,11?,12+,16-,17-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601906
(CHEMBL5204305)Show SMILES CC(C)[C@H](NC(=O)Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C)C(=O)C(F)(F)C(=O)NCC(O)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100886
(CHEMBL3325858)Show SMILES Cl.CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NC(C)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C28H49N7O10.ClH/c1-7-14(2)21(34-25(42)19(33-18(6)37)10-8-9-12-29)26(43)35-22(17(5)36)27(44)32-16(4)24(41)31-15(3)23(40)28(45)30-13-11-20(38)39;/h14-17,19,21-22,36H,7-13,29H2,1-6H3,(H,30,45)(H,31,41)(H,32,44)(H,33,37)(H,34,42)(H,35,43)(H,38,39);1H/t14-,15?,16-,17+,19-,21-,22-;/m0./s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100698
(CHEMBL3326343)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NC(CC)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C22H37N5O9/c1-6-11(3)17(25-13(5)29)21(35)27-18(12(4)28)20(34)24-10-15(30)26-14(7-2)19(33)22(36)23-9-8-16(31)32/h11-12,14,17-18,28H,6-10H2,1-5H3,(H,23,36)(H,24,34)(H,25,29)(H,26,30)(H,27,35)(H,31,32)/t11-,12+,14?,17-,18-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100882
(CHEMBL3325862)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NC(C)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C22H37N5O9/c1-7-10(2)16(26-14(6)29)20(34)27-17(13(5)28)21(35)25-12(4)19(33)24-11(3)18(32)22(36)23-9-8-15(30)31/h10-13,16-17,28H,7-9H2,1-6H3,(H,23,36)(H,24,33)(H,25,35)(H,26,29)(H,27,34)(H,30,31)/t10-,11?,12-,13+,16-,17-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100885
(CHEMBL3325859)Show SMILES Cl.CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NC(C)C(=O)C(=O)NCCCC(O)=O |r| Show InChI InChI=1S/C29H51N7O10.ClH/c1-7-15(2)22(35-26(43)20(34-19(6)38)11-8-9-13-30)27(44)36-23(18(5)37)28(45)33-17(4)25(42)32-16(3)24(41)29(46)31-14-10-12-21(39)40;/h15-18,20,22-23,37H,7-14,30H2,1-6H3,(H,31,46)(H,32,42)(H,33,45)(H,34,38)(H,35,43)(H,36,44)(H,39,40);1H/t15-,16?,17-,18+,20-,22-,23-;/m0./s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100697
(CHEMBL3326344)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NC(CO)C(=O)C(=O)NCCCO |r| Show InChI InChI=1S/C21H37N5O9/c1-5-11(2)16(24-13(4)30)20(34)26-17(12(3)29)19(33)23-9-15(31)25-14(10-28)18(32)21(35)22-7-6-8-27/h11-12,14,16-17,27-29H,5-10H2,1-4H3,(H,22,35)(H,23,33)(H,24,30)(H,25,31)(H,26,34)/t11-,12+,14?,16-,17-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100696
(CHEMBL3326345)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NC(C(C)C)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C23H39N5O9/c1-7-12(4)18(26-14(6)30)22(36)28-19(13(5)29)21(35)25-10-15(31)27-17(11(2)3)20(34)23(37)24-9-8-16(32)33/h11-13,17-19,29H,7-10H2,1-6H3,(H,24,37)(H,25,35)(H,26,30)(H,27,31)(H,28,36)(H,32,33)/t12-,13+,17?,18-,19-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601902
(CHEMBL5201848)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H](NC(C)=O)C1CCCC1)C(=O)NCC(=O)N[C@H]1CCOB1O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100705
(CHEMBL3326340)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NC(CCC(O)=O)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C24H39N5O11/c1-6-11(2)18(27-14(5)31)22(38)29-19(13(4)30)23(39)26-12(3)21(37)28-15(7-8-16(32)33)20(36)24(40)25-10-9-17(34)35/h11-13,15,18-19,30H,6-10H2,1-5H3,(H,25,40)(H,26,39)(H,27,31)(H,28,37)(H,29,38)(H,32,33)(H,34,35)/t11-,12-,13+,15?,18-,19-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50045202
(CHEMBL3310709)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)C(F)(F)C(=O)NCC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C50H65F2N7O12/c1-7-31(2)41(58-45(64)39(57-35(6)60)25-17-18-26-53-49(68)71-30-38-23-15-10-16-24-38)46(65)59-42(34(5)69-28-36-19-11-8-12-20-36)47(66)56-33(4)44(63)55-32(3)43(62)50(51,52)48(67)54-27-40(61)70-29-37-21-13-9-14-22-37/h8-16,19-24,31-34,39,41-42H,7,17-18,25-30H2,1-6H3,(H,53,68)(H,54,67)(H,55,63)(H,56,66)(H,57,60)(H,58,64)(H,59,65)/t31-,32-,33-,34+,39-,41-,42-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum serine protease subtilisin-like protease 1by fluorimetric assay |
Bioorg Med Chem Lett 24: 3582-6 (2014)
Article DOI: 10.1016/j.bmcl.2014.05.044
BindingDB Entry DOI: 10.7270/Q22Z175D |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601904
(CHEMBL5184663)Show SMILES CC(C)[C@H](NC(=O)[C@@H](NC(C)=O)C1CCCC1)C(=O)NCC(=O)N[C@@H](C)B(O)O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601897
(CHEMBL5205624)Show SMILES Cl.CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC)C(=O)C(=O)NC1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100892
(CHEMBL3354605)Show SMILES Cl.CC[C@@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NC(CCC(N)=O)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C30H52N8O11.ClH/c1-6-15(2)23(37-27(46)20(35-18(5)40)9-7-8-13-31)28(47)38-24(17(4)39)29(48)34-16(3)26(45)36-19(10-11-21(32)41)25(44)30(49)33-14-12-22(42)43;/h15-17,19-20,23-24,39H,6-14,31H2,1-5H3,(H2,32,41)(H,33,49)(H,34,48)(H,35,40)(H,36,45)(H,37,46)(H,38,47)(H,42,43);1H/t15-,16+,17-,19?,20+,23+,24+;/m1./s1 | PDB
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601903
(CHEMBL5194400)Show SMILES C[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](NC(C)=O)C1CCCC1)B(O)O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601901
(CHEMBL5180525)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H](NC(C)=O)C1CCCC1)C(=O)NCC(=O)N[C@@H](C)B(O)O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100884
(CHEMBL3325860)Show SMILES Cl.CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NC(C)C(=O)C(=O)NCC(O)=O |r| Show InChI InChI=1S/C27H47N7O10.ClH/c1-7-13(2)20(33-24(41)18(32-17(6)36)10-8-9-11-28)25(42)34-21(16(5)35)26(43)31-15(4)23(40)30-14(3)22(39)27(44)29-12-19(37)38;/h13-16,18,20-21,35H,7-12,28H2,1-6H3,(H,29,44)(H,30,40)(H,31,43)(H,32,36)(H,33,41)(H,34,42)(H,37,38);1H/t13-,14?,15-,16+,18-,20-,21-;/m0./s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601909
(CHEMBL537778 | GNF-Pf-2233 | MMV007224 | TCMDC-125...) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601912
(CHEMBL5204930)Show SMILES CS(=O)(=O)Nc1cc2nc(Nc3ccc(Br)cc3)c(Nc3ccc(Br)cc3)nc2cc1Cl | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601910
(CHEMBL5192502)Show SMILES Clc1cc(Nc2nc3ccccc3nc2Nc2ccc(Br)c(Cl)c2)ccc1Br | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601911
(CHEMBL5172494)Show SMILES Nc1cc2nc(Nc3ccc(Br)cc3)c(Nc3ccc(Br)cc3)nc2cc1Cl | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601899
(CHEMBL5182025)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)CCC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100889
(CHEMBL3325856)Show SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)Nc3ccc4c(Cl)c(OCCc5ccccc5)oc(=O)c4c3)[C@@]1([H])NC(=O)N2 |r| Show InChI InChI=1S/C39H50ClN5O7S/c40-35-28-19-18-27(24-29(28)37(49)52-38(35)51-23-20-26-12-4-1-5-13-26)43-34(48)17-7-3-11-22-41-32(46)15-6-2-10-21-42-33(47)16-9-8-14-31-36-30(25-53-31)44-39(50)45-36/h1,4-5,12-13,18-19,24,30-31,36H,2-3,6-11,14-17,20-23,25H2,(H,41,46)(H,42,47)(H,43,48)(H2,44,45,50)/t30-,31-,36-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601913
(CHEMBL1241101)Show SMILES [H][C@@]12CS[C@H](CCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)Nc3ccc4c(Cl)c(OCCc5ccccc5)oc(=O)c4c3)[C@]1([H])NC(=O)N2 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50388064
(CHEMBL1237284 | TCMDC-123970)Show SMILES COc1ccc2nc(C)cc(N=NCc3ccc(cc3)[N+]([O-])=O)c2c1 |w:11.10| Show InChI InChI=1S/C18H16N4O3/c1-12-9-18(16-10-15(25-2)7-8-17(16)20-12)21-19-11-13-3-5-14(6-4-13)22(23)24/h3-10H,11H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 by fluorimetric assay |
Bioorg Med Chem Lett 22: 5317-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.023
BindingDB Entry DOI: 10.7270/Q2SF2X79 |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50388063
(CHEMBL2059468)Show SMILES Cc1cc(N=NCc2ccc(cc2)[N+]([O-])=O)c2cc3OCOc3cc2n1 |w:4.3| Show InChI InChI=1S/C18H14N4O4/c1-11-6-16(14-7-17-18(26-10-25-17)8-15(14)20-11)21-19-9-12-2-4-13(5-3-12)22(23)24/h2-8H,9-10H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 by fluorimetric assay |
Bioorg Med Chem Lett 22: 5317-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.023
BindingDB Entry DOI: 10.7270/Q2SF2X79 |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100737
(CHEMBL3326338)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NC(C(C)C)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C24H41N5O9/c1-8-12(4)18(27-15(7)31)22(36)29-19(14(6)30)23(37)26-13(5)21(35)28-17(11(2)3)20(34)24(38)25-10-9-16(32)33/h11-14,17-19,30H,8-10H2,1-7H3,(H,25,38)(H,26,37)(H,27,31)(H,28,35)(H,29,36)(H,32,33)/t12-,13-,14+,17?,18-,19-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100878
(CHEMBL3326335)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NC(C)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C21H35N5O8/c1-7-10(2)16(26-14(6)27)20(33)25-13(5)19(32)24-12(4)18(31)23-11(3)17(30)21(34)22-9-8-15(28)29/h10-13,16H,7-9H2,1-6H3,(H,22,34)(H,23,31)(H,24,32)(H,25,33)(H,26,27)(H,28,29)/t10-,11?,12-,13-,16-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50045203
(CHEMBL3310710)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)C(F)(F)C(=O)NCC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C36H47F2N5O9/c1-7-21(2)29(42-25(6)44)33(48)43-30(24(5)51-19-26-14-10-8-11-15-26)34(49)41-23(4)32(47)40-22(3)31(46)36(37,38)35(50)39-18-28(45)52-20-27-16-12-9-13-17-27/h8-17,21-24,29-30H,7,18-20H2,1-6H3,(H,39,50)(H,40,47)(H,41,49)(H,42,44)(H,43,48)/t21-,22-,23-,24+,29-,30-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum serine protease subtilisin-like protease 1by fluorimetric assay |
Bioorg Med Chem Lett 24: 3582-6 (2014)
Article DOI: 10.1016/j.bmcl.2014.05.044
BindingDB Entry DOI: 10.7270/Q22Z175D |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100883
(CHEMBL3325861)Show SMILES Cl.CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NC(C)C(=O)C(=O)NCCC(N)=O |r| Show InChI InChI=1S/C28H50N8O9.ClH/c1-7-14(2)21(35-25(42)19(34-18(6)38)10-8-9-12-29)26(43)36-22(17(5)37)27(44)33-16(4)24(41)32-15(3)23(40)28(45)31-13-11-20(30)39;/h14-17,19,21-22,37H,7-13,29H2,1-6H3,(H2,30,39)(H,31,45)(H,32,41)(H,33,44)(H,34,38)(H,35,42)(H,36,43);1H/t14-,15?,16-,17+,19-,21-,22-;/m0./s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50388062
(CHEMBL2059472)Show SMILES Cc1cc(N=NCc2ccc(cc2)C#N)c2cc3OCOc3cc2n1 |w:4.3| Show InChI InChI=1S/C19H14N4O2/c1-12-6-17(23-21-10-14-4-2-13(9-20)3-5-14)15-7-18-19(25-11-24-18)8-16(15)22-12/h2-8H,10-11H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 by fluorimetric assay |
Bioorg Med Chem Lett 22: 5317-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.023
BindingDB Entry DOI: 10.7270/Q2SF2X79 |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50388061
(CHEMBL2057540)Show SMILES Cc1cc(N=NCc2ccccc2[N+]([O-])=O)c2cc3OCOc3cc2n1 |w:4.3| Show InChI InChI=1S/C18H14N4O4/c1-11-6-15(13-7-17-18(26-10-25-17)8-14(13)20-11)21-19-9-12-4-2-3-5-16(12)22(23)24/h2-8H,9-10H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 by fluorimetric assay |
Bioorg Med Chem Lett 22: 5317-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.023
BindingDB Entry DOI: 10.7270/Q2SF2X79 |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100877
(CHEMBL3326336)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](C)NC(C)=O)C(=O)NCC(=O)NC(C)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C18H29N5O9/c1-8(15(29)18(32)19-6-5-13(27)28)22-12(26)7-20-17(31)14(10(3)24)23-16(30)9(2)21-11(4)25/h8-10,14,24H,5-7H2,1-4H3,(H,19,32)(H,20,31)(H,21,25)(H,22,26)(H,23,30)(H,27,28)/t8?,9-,10+,14-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601908
(CHEMBL5169486)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)C(F)(F)C(O)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50601907
(CHEMBL5199452)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01093
BindingDB Entry DOI: 10.7270/Q2NK3K4B |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100733
(CHEMBL3326339)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NC(C(=O)C(=O)NCCC(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C27H39N5O9/c1-6-14(2)20(30-17(5)34)25(39)31-21(16(4)33)26(40)29-15(3)24(38)32-22(18-10-8-7-9-11-18)23(37)27(41)28-13-12-19(35)36/h7-11,14-16,20-22,33H,6,12-13H2,1-5H3,(H,28,41)(H,29,40)(H,30,34)(H,31,39)(H,32,38)(H,35,36)/t14-,15-,16+,20-,21-,22?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100702
(CHEMBL3326341)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NC(CCC(=O)N(C)C)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C26H44N6O10/c1-8-13(2)20(29-16(5)34)24(40)31-21(15(4)33)25(41)28-14(3)23(39)30-17(9-10-18(35)32(6)7)22(38)26(42)27-12-11-19(36)37/h13-15,17,20-21,33H,8-12H2,1-7H3,(H,27,42)(H,28,41)(H,29,34)(H,30,39)(H,31,40)(H,36,37)/t13-,14-,15+,17?,20-,21-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50100881
(CHEMBL3325863)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NC(C)(C)C(=O)NC(C)C(=O)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C23H39N5O9/c1-8-11(2)16(26-14(5)30)19(34)27-17(13(4)29)20(35)28-23(6,7)22(37)25-12(3)18(33)21(36)24-10-9-15(31)32/h11-13,16-17,29H,8-10H2,1-7H3,(H,24,36)(H,25,37)(H,26,30)(H,27,34)(H,28,35)(H,31,32)/t11-,12?,13+,16-,17-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 |
Bioorg Med Chem Lett 24: 4486-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.086
BindingDB Entry DOI: 10.7270/Q2DJ5HDB |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50388067
(CHEMBL2059462)Show SMILES [O-][N+](=O)c1ccc(CN=Nc2nc3ccccc3[nH]2)cc1 |w:9.9| Show InChI InChI=1S/C14H11N5O2/c20-19(21)11-7-5-10(6-8-11)9-15-18-14-16-12-3-1-2-4-13(12)17-14/h1-8H,9H2,(H,16,17) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 by fluorimetric assay |
Bioorg Med Chem Lett 22: 5317-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.023
BindingDB Entry DOI: 10.7270/Q2SF2X79 |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50388065
(CHEMBL1237282 | TCMDC-142139)Show SMILES COc1ccc2nccc(N=NCc3ccc(cc3)[N+]([O-])=O)c2c1 |w:10.9| Show InChI InChI=1S/C17H14N4O3/c1-24-14-6-7-16-15(10-14)17(8-9-18-16)20-19-11-12-2-4-13(5-3-12)21(22)23/h2-10H,11H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 by fluorimetric assay |
Bioorg Med Chem Lett 22: 5317-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.023
BindingDB Entry DOI: 10.7270/Q2SF2X79 |
More data for this
Ligand-Target Pair | |
Subtilisin-like protease 1
(Plasmodium falciparum) | BDBM50388066
(CHEMBL2059464)Show SMILES [O-][N+](=O)c1ccc(CN=Nc2c3CCCCc3nc3ccccc23)cc1 |w:9.9| Show InChI InChI=1S/C20H18N4O2/c25-24(26)15-11-9-14(10-12-15)13-21-23-20-16-5-1-3-7-18(16)22-19-8-4-2-6-17(19)20/h1,3,5,7,9-12H,2,4,6,8,13H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum SUB1 by fluorimetric assay |
Bioorg Med Chem Lett 22: 5317-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.023
BindingDB Entry DOI: 10.7270/Q2SF2X79 |
More data for this
Ligand-Target Pair | |
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