BindingDB PrimarySearch

Found 12 hits of ic50 data for polymerid = 50006276
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50412352 (CHEMBL5278336) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AChE in organophosphate-susceptible clone of Schizaphis graminum OSS adult or last-instar nymphs homogenates assessed as bimolecular ra...				Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437695 (CHEMBL1923233) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of USP5 in human Z138 cells after 1 hr by immunoblotting analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
Tokyo University of Agriculture Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50412352 (CHEMBL5278336) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AChE in organophosphate-resistant clone of Schizaphis graminum OR1 adult or last-instar nymphs homogenates assessed as bimolecular rate...				Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50538571 (CHEMBL4635160) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human 6His-tagged USP5 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...				J Med Chem 63: 5398-5420 (2020) Article DOI: 10.1021/acs.jmedchem.0c00245 BindingDB Entry DOI: 10.7270/Q2XK8K2T
RAPT Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50608542 (CHEMBL5276142) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PDB UniChem		n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50412352 (CHEMBL5278336) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AChE in organophosphate-susceptible clone of Schizaphis graminum OSS adult or last-instar nymphs homogenates assessed as bimolecular ra...				Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50608541 (CHEMBL1493046) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50412352 (CHEMBL5278336) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AChE in organophosphate-resistant clone of Schizaphis graminum OR1 adult or last-instar nymphs homogenates assessed as bimolecular rate...				Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437694 (CHEMBL1410015) Show SMILES Cc1cc(C(=O)CN2CCCC2)c(C)n1-c1ccc(F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars		n/a	n/a	1.43E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50271098 (CHEMBL4129140) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Progenra, Inc. Curated by ChEMBL					Assay Description Inhibition of USP5 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluor...				J Med Chem 61: 422-443 (2018) Article DOI: 10.1021/acs.jmedchem.7b00498 BindingDB Entry DOI: 10.7270/Q2CR5WVG
Progenra, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50608424 (CHEMBL5267683) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair