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Compile Data Set for Download or QSAR

Found 194 hits of ec50 for UniProtKB: P19550   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324123
PNG
(US10189816, Compound 116)
Show SMILES COc1ccc(F)c(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)c1 |r|
Show InChI InChI=1S/C37H48FN3O4/c1-23-31(26-9-10-27-21-40(16-13-25(27)19-26)22-28-20-29(44-8)11-12-30(28)38)33(41-17-14-37(6,7)15-18-41)32(24(2)39-23)34(35(42)43)45-36(3,4)5/h9-12,19-20,34H,13-18,21-22H2,1-8H3,(H,42,43)/t34-/m0/s1
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n/an/an/an/a 2n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324103
PNG
(US10189816, Compound 96)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cc(F)cc(F)c4F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H44F3N3O3/c1-21-29(24-8-9-25-19-41(13-10-23(25)16-24)20-26-17-27(37)18-28(38)31(26)39)32(42-14-11-36(6,7)12-15-42)30(22(2)40-21)33(34(43)44)45-35(3,4)5/h8-9,16-18,33H,10-15,19-20H2,1-7H3,(H,43,44)/t33-/m0/s1
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ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324171
PNG
(US10189816, Compound 164)
Show SMILES Cc1cccc(Cl)c1CN1CCc2cc(ccc2C1)-c1cnc(C)c([C@H](OC(C)(C)C)C(O)=O)c1N1CCC(C)(C)CC1 |r|
Show InChI InChI=1S/C36H46ClN3O3/c1-23-9-8-10-30(37)29(23)22-39-16-13-25-19-26(11-12-27(25)21-39)28-20-38-24(2)31(33(34(41)42)43-35(3,4)5)32(28)40-17-14-36(6,7)15-18-40/h8-12,19-20,33H,13-18,21-22H2,1-7H3,(H,41,42)/t33-/m0/s1
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ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324136
PNG
(US10189816, Compound 129)
Show SMILES COc1cccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)c1Cl |r|
Show InChI InChI=1S/C37H48ClN3O4/c1-23-30(26-12-13-27-21-40(17-14-25(27)20-26)22-28-10-9-11-29(44-8)32(28)38)33(41-18-15-37(6,7)16-19-41)31(24(2)39-23)34(35(42)43)45-36(3,4)5/h9-13,20,34H,14-19,21-22H2,1-8H3,(H,42,43)/t34-/m0/s1
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ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324087
PNG
(US10189816, Compound 80)
Show SMILES Cc1cccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)c1C |r|
Show InChI InChI=1S/C38H51N3O3/c1-24-11-10-12-30(25(24)2)22-40-18-15-28-21-29(13-14-31(28)23-40)32-26(3)39-27(4)33(35(36(42)43)44-37(5,6)7)34(32)41-19-16-38(8,9)17-20-41/h10-14,21,35H,15-20,22-23H2,1-9H3,(H,42,43)/t35-/m0/s1
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n/an/an/an/a 3n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324058
PNG
(US10189816, Compound 51)
Show SMILES Cc1cccc(F)c1CN1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1N1CCC(C)(C)CC1 |r|
Show InChI InChI=1S/C37H48FN3O3/c1-23-10-9-11-30(38)29(23)22-40-17-14-26-20-27(12-13-28(26)21-40)31-24(2)39-25(3)32(34(35(42)43)44-36(4,5)6)33(31)41-18-15-37(7,8)16-19-41/h9-13,20,34H,14-19,21-22H2,1-8H3,(H,42,43)/t34-/m0/s1
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n/an/an/an/a 3n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324052
PNG
(US10189816, Compound 45)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cc(F)ccc4Cl)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H45ClFN3O3/c1-22-30(25-8-9-26-20-40(15-12-24(26)18-25)21-27-19-28(38)10-11-29(27)37)32(41-16-13-36(6,7)14-17-41)31(23(2)39-22)33(34(42)43)44-35(3,4)5/h8-11,18-19,33H,12-17,20-21H2,1-7H3,(H,42,43)/t33-/m0/s1
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ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324030
PNG
(US10189816, Compound 23)
Show SMILES Cc1cccc(Cl)c1CN1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1N1CCC(C)(C)CC1 |r|
Show InChI InChI=1S/C37H48ClN3O3/c1-23-10-9-11-30(38)29(23)22-40-17-14-26-20-27(12-13-28(26)21-40)31-24(2)39-25(3)32(34(35(42)43)44-36(4,5)6)33(31)41-18-15-37(7,8)16-19-41/h9-13,20,34H,14-19,21-22H2,1-8H3,(H,42,43)/t34-/m0/s1
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n/an/an/an/a 3n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324014
PNG
(US10189816, Compound 7)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cccc(F)c4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H46FN3O3/c1-23-30(27-11-12-28-22-39(16-13-26(28)20-27)21-25-9-8-10-29(37)19-25)32(40-17-14-36(6,7)15-18-40)31(24(2)38-23)33(34(41)42)43-35(3,4)5/h8-12,19-20,33H,13-18,21-22H2,1-7H3,(H,41,42)/t33-/m0/s1
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n/an/an/an/a 4n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324045
PNG
(US10189816, Compound 38)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cc(F)ccc4F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H45F2N3O3/c1-22-30(25-8-9-26-20-40(15-12-24(26)18-25)21-27-19-28(37)10-11-29(27)38)32(41-16-13-36(6,7)14-17-41)31(23(2)39-22)33(34(42)43)44-35(3,4)5/h8-11,18-19,33H,12-17,20-21H2,1-7H3,(H,42,43)/t33-/m0/s1
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ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM323830
PNG
(US10189816, Compound 1)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccc(F)cc4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H46FN3O3/c1-23-30(27-10-11-28-22-39(17-14-26(28)20-27)21-25-8-12-29(37)13-9-25)32(40-18-15-36(6,7)16-19-40)31(24(2)38-23)33(34(41)42)43-35(3,4)5/h8-13,20,33H,14-19,21-22H2,1-7H3,(H,41,42)/t33-/m0/s1
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ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324080
PNG
(US10189816, Compound 73)
Show SMILES Cc1ccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)c(F)c1F |r|
Show InChI InChI=1S/C37H47F2N3O3/c1-22-9-10-28(32(39)31(22)38)21-41-16-13-25-19-26(11-12-27(25)20-41)29-23(2)40-24(3)30(34(35(43)44)45-36(4,5)6)33(29)42-17-14-37(7,8)15-18-42/h9-12,19,34H,13-18,20-21H2,1-8H3,(H,43,44)/t34-/m0/s1
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ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324163
PNG
(US10189816, Compound 156)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccc5OCCOc5c4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C38H49N3O5/c1-24-32(34(41-16-13-38(6,7)14-17-41)33(25(2)39-24)35(36(42)43)46-37(3,4)5)28-9-10-29-23-40(15-12-27(29)21-28)22-26-8-11-30-31(20-26)45-19-18-44-30/h8-11,20-21,35H,12-19,22-23H2,1-7H3,(H,42,43)/t35-/m0/s1
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ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324117
PNG
(US10189816, Compound 110)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cccc(OC(F)(F)F)c4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C37H46F3N3O4/c1-23-30(32(43-17-14-36(6,7)15-18-43)31(24(2)41-23)33(34(44)45)47-35(3,4)5)27-11-12-28-22-42(16-13-26(28)20-27)21-25-9-8-10-29(19-25)46-37(38,39)40/h8-12,19-20,33H,13-18,21-22H2,1-7H3,(H,44,45)/t33-/m0/s1
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ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324151
PNG
(US10189816, Compound 144)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4c(O)cc(F)cc4F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H45F2N3O4/c1-21-30(24-8-9-25-19-40(13-10-23(25)16-24)20-27-28(38)17-26(37)18-29(27)42)32(41-14-11-36(6,7)12-15-41)31(22(2)39-21)33(34(43)44)45-35(3,4)5/h8-9,16-18,33,42H,10-15,19-20H2,1-7H3,(H,43,44)/t33-/m0/s1
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n/an/an/an/a 8n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324038
PNG
(US10189816, Compound 31)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cc(F)cc(F)c4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H45F2N3O3/c1-22-30(26-8-9-27-21-40(13-10-25(27)18-26)20-24-16-28(37)19-29(38)17-24)32(41-14-11-36(6,7)12-15-41)31(23(2)39-22)33(34(42)43)44-35(3,4)5/h8-9,16-19,33H,10-15,20-21H2,1-7H3,(H,42,43)/t33-/m0/s1
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n/an/an/an/a 11n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324130
PNG
(US10189816, Compound 123)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccccc4OC(F)(F)F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C37H46F3N3O4/c1-23-30(32(43-18-15-36(6,7)16-19-43)31(24(2)41-23)33(34(44)45)47-35(3,4)5)26-12-13-27-21-42(17-14-25(27)20-26)22-28-10-8-9-11-29(28)46-37(38,39)40/h8-13,20,33H,14-19,21-22H2,1-7H3,(H,44,45)/t33-/m0/s1
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n/an/an/an/a 11n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324095
PNG
(US10189816, Compound 88)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccccc4OCCO)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C38H51N3O5/c1-25-32(28-12-13-29-23-40(17-14-27(29)22-28)24-30-10-8-9-11-31(30)45-21-20-42)34(41-18-15-38(6,7)16-19-41)33(26(2)39-25)35(36(43)44)46-37(3,4)5/h8-13,22,35,42H,14-21,23-24H2,1-7H3,(H,43,44)/t35-/m0/s1
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n/an/an/an/a 12n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324110
PNG
(US10189816, Compound 103)
Show SMILES CCOc1cccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)c1 |r|
Show InChI InChI=1S/C38H51N3O4/c1-9-44-31-12-10-11-27(21-31)23-40-18-15-28-22-29(13-14-30(28)24-40)32-25(2)39-26(3)33(35(36(42)43)45-37(4,5)6)34(32)41-19-16-38(7,8)17-20-41/h10-14,21-22,35H,9,15-20,23-24H2,1-8H3,(H,42,43)/t35-/m0/s1
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n/an/an/an/a 12n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324141
PNG
(US10189816, Compound 134)
Show SMILES Cc1cc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)ccc1Cl |r|
Show InChI InChI=1S/C37H48ClN3O3/c1-23-19-26(9-12-30(23)38)21-40-16-13-27-20-28(10-11-29(27)22-40)31-24(2)39-25(3)32(34(35(42)43)44-36(4,5)6)33(31)41-17-14-37(7,8)15-18-41/h9-12,19-20,34H,13-18,21-22H2,1-8H3,(H,42,43)/t34-/m0/s1
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n/an/an/an/a 12n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324073
PNG
(US10189816, Compound 66)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cc(F)ccc4C(F)(F)F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C37H45F4N3O3/c1-22-30(32(44-16-13-36(6,7)14-17-44)31(23(2)42-22)33(34(45)46)47-35(3,4)5)25-8-9-26-20-43(15-12-24(26)18-25)21-27-19-28(38)10-11-29(27)37(39,40)41/h8-11,18-19,33H,12-17,20-21H2,1-7H3,(H,45,46)/t33-/m0/s1
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n/an/an/an/a 13n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324157
PNG
(US10189816, Compound 150)
Show SMILES CC(C)Oc1ccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)cc1 |r|
Show InChI InChI=1S/C39H53N3O4/c1-25(2)45-32-14-10-28(11-15-32)23-41-19-16-29-22-30(12-13-31(29)24-41)33-26(3)40-27(4)34(36(37(43)44)46-38(5,6)7)35(33)42-20-17-39(8,9)18-21-42/h10-15,22,25,36H,16-21,23-24H2,1-9H3,(H,43,44)/t36-/m0/s1
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n/an/an/an/a 21n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324173
PNG
(US10189816, Compound 166)
Show SMILES Cc1cccc(Cl)c1CN1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1N1CCCC(C)(C)C1 |r|
Show InChI InChI=1S/C37H48ClN3O3/c1-23-11-9-12-30(38)29(23)21-40-18-15-26-19-27(13-14-28(26)20-40)31-24(2)39-25(3)32(34(35(42)43)44-36(4,5)6)33(31)41-17-10-16-37(7,8)22-41/h9,11-14,19,34H,10,15-18,20-22H2,1-8H3,(H,42,43)/t34-/m0/s1
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n/an/an/an/a 23n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324146
PNG
(US10189816, Compound 139)
Show SMILES COc1ccc(cc1CN1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1N1CCC(C)(C)CC1)C(C)C |r|
Show InChI InChI=1S/C40H55N3O4/c1-25(2)28-13-14-33(46-10)32(21-28)24-42-18-15-29-22-30(11-12-31(29)23-42)34-26(3)41-27(4)35(37(38(44)45)47-39(5,6)7)36(34)43-19-16-40(8,9)17-20-43/h11-14,21-22,25,37H,15-20,23-24H2,1-10H3,(H,44,45)/t37-/m0/s1
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n/an/an/an/a 30n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324021
PNG
(US10189816, Compound 14)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccc(cc4)-c4ccccc4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C42H51N3O3/c1-28-36(38(45-23-20-42(6,7)21-24-45)37(29(2)43-28)39(40(46)47)48-41(3,4)5)34-17-18-35-27-44(22-19-33(35)25-34)26-30-13-15-32(16-14-30)31-11-9-8-10-12-31/h8-18,25,39H,19-24,26-27H2,1-7H3,(H,46,47)/t39-/m0/s1
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n/an/an/an/a 34n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324066
PNG
(US10189816, Compound 59)
Show SMILES CC(C)c1ccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)cc1 |r|
Show InChI InChI=1S/C39H53N3O3/c1-25(2)29-12-10-28(11-13-29)23-41-19-16-30-22-31(14-15-32(30)24-41)33-26(3)40-27(4)34(36(37(43)44)45-38(5,6)7)35(33)42-20-17-39(8,9)18-21-42/h10-15,22,25,36H,16-21,23-24H2,1-9H3,(H,43,44)/t36-/m0/s1
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n/an/an/an/a 58n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324170
PNG
(US10189816, Compound 163)
Show SMILES CCCCCCCCCOc1ccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)cc1 |r|
Show InChI InChI=1S/C45H65N3O4/c1-9-10-11-12-13-14-15-28-51-38-20-16-34(17-21-38)30-47-25-22-35-29-36(18-19-37(35)31-47)39-32(2)46-33(3)40(42(43(49)50)52-44(4,5)6)41(39)48-26-23-45(7,8)24-27-48/h16-21,29,42H,9-15,22-28,30-31H2,1-8H3,(H,49,50)/t42-/m0/s1
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n/an/an/an/a 76n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM323830
PNG
(US10189816, Compound 1)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccc(F)cc4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H46FN3O3/c1-23-30(27-10-11-28-22-39(17-14-26(28)20-27)21-25-8-12-29(37)13-9-25)32(40-18-15-36(6,7)16-19-40)31(24(2)38-23)33(34(41)42)43-35(3,4)5/h8-13,20,33H,14-19,21-22H2,1-7H3,(H,41,42)/t33-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324009
PNG
(US10189816, Compound 2)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cccc(c4)C(F)(F)F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C37H46F3N3O3/c1-23-30(27-11-12-28-22-42(16-13-26(28)20-27)21-25-9-8-10-29(19-25)37(38,39)40)32(43-17-14-36(6,7)15-18-43)31(24(2)41-23)33(34(44)45)46-35(3,4)5/h8-12,19-20,33H,13-18,21-22H2,1-7H3,(H,44,45)/t33-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324010
PNG
(US10189816, Compound 3)
Show SMILES Cc1cccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)c1 |r|
Show InChI InChI=1S/C37H49N3O3/c1-24-10-9-11-27(20-24)22-39-17-14-28-21-29(12-13-30(28)23-39)31-25(2)38-26(3)32(34(35(41)42)43-36(4,5)6)33(31)40-18-15-37(7,8)16-19-40/h9-13,20-21,34H,14-19,22-23H2,1-8H3,(H,41,42)/t34-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324011
PNG
(US10189816, Compound 4)
Show SMILES Cc1ccccc1CN1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1N1CCC(C)(C)CC1 |r|
Show InChI InChI=1S/C37H49N3O3/c1-24-11-9-10-12-29(24)22-39-18-15-27-21-28(13-14-30(27)23-39)31-25(2)38-26(3)32(34(35(41)42)43-36(4,5)6)33(31)40-19-16-37(7,8)17-20-40/h9-14,21,34H,15-20,22-23H2,1-8H3,(H,41,42)/t34-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324012
PNG
(US10189816, Compound 5)
Show SMILES Cc1ccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)cc1 |r|
Show InChI InChI=1S/C37H49N3O3/c1-24-9-11-27(12-10-24)22-39-18-15-28-21-29(13-14-30(28)23-39)31-25(2)38-26(3)32(34(35(41)42)43-36(4,5)6)33(31)40-19-16-37(7,8)17-20-40/h9-14,21,34H,15-20,22-23H2,1-8H3,(H,41,42)/t34-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324013
PNG
(US10189816, Compound 6)
Show SMILES COc1cccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)c1 |r|
Show InChI InChI=1S/C37H49N3O4/c1-24-31(28-12-13-29-23-39(17-14-27(29)21-28)22-26-10-9-11-30(20-26)43-8)33(40-18-15-37(6,7)16-19-40)32(25(2)38-24)34(35(41)42)44-36(3,4)5/h9-13,20-21,34H,14-19,22-23H2,1-8H3,(H,41,42)/t34-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324014
PNG
(US10189816, Compound 7)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cccc(F)c4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H46FN3O3/c1-23-30(27-11-12-28-22-39(16-13-26(28)20-27)21-25-9-8-10-29(37)19-25)32(40-17-14-36(6,7)15-18-40)31(24(2)38-23)33(34(41)42)43-35(3,4)5/h8-12,19-20,33H,13-18,21-22H2,1-7H3,(H,41,42)/t33-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324015
PNG
(US10189816, Compound 8)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccc(cc4)C(F)(F)F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C37H46F3N3O3/c1-23-30(27-10-11-28-22-42(17-14-26(28)20-27)21-25-8-12-29(13-9-25)37(38,39)40)32(43-18-15-36(6,7)16-19-43)31(24(2)41-23)33(34(44)45)46-35(3,4)5/h8-13,20,33H,14-19,21-22H2,1-7H3,(H,44,45)/t33-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324016
PNG
(US10189816, Compound 9)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccccc4F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H46FN3O3/c1-23-30(26-12-13-27-21-39(17-14-25(27)20-26)22-28-10-8-9-11-29(28)37)32(40-18-15-36(6,7)16-19-40)31(24(2)38-23)33(34(41)42)43-35(3,4)5/h8-13,20,33H,14-19,21-22H2,1-7H3,(H,41,42)/t33-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324018
PNG
(US10189816, Compound 11)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cccc(c4)-c4ccccc4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C42H51N3O3/c1-28-36(38(45-22-19-42(6,7)20-23-45)37(29(2)43-28)39(40(46)47)48-41(3,4)5)34-16-17-35-27-44(21-18-33(35)25-34)26-30-12-11-15-32(24-30)31-13-9-8-10-14-31/h8-17,24-25,39H,18-23,26-27H2,1-7H3,(H,46,47)/t39-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324019
PNG
(US10189816, Compound 12)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccccc4C(F)(F)F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C37H46F3N3O3/c1-23-30(26-12-13-27-21-42(17-14-25(27)20-26)22-28-10-8-9-11-29(28)37(38,39)40)32(43-18-15-36(6,7)16-19-43)31(24(2)41-23)33(34(44)45)46-35(3,4)5/h8-13,20,33H,14-19,21-22H2,1-7H3,(H,44,45)/t33-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324020
PNG
(US10189816, Compound 13)
Show SMILES CC(N1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1N1CCC(C)(C)CC1)c1ccccc1 |r|
Show InChI InChI=1S/C37H49N3O3/c1-24-31(29-14-15-30-23-40(19-16-28(30)22-29)26(3)27-12-10-9-11-13-27)33(39-20-17-37(7,8)18-21-39)32(25(2)38-24)34(35(41)42)43-36(4,5)6/h9-15,22,26,34H,16-21,23H2,1-8H3,(H,41,42)/t26?,34-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324021
PNG
(US10189816, Compound 14)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccc(cc4)-c4ccccc4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C42H51N3O3/c1-28-36(38(45-23-20-42(6,7)21-24-45)37(29(2)43-28)39(40(46)47)48-41(3,4)5)34-17-18-35-27-44(22-19-33(35)25-34)26-30-13-15-32(16-14-30)31-11-9-8-10-12-31/h8-18,25,39H,19-24,26-27H2,1-7H3,(H,46,47)/t39-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324022
PNG
(US10189816, Compound 15)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cccc(c4C)C(F)(F)F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C38H48F3N3O3/c1-23-28(10-9-11-30(23)38(39,40)41)21-43-17-14-26-20-27(12-13-29(26)22-43)31-24(2)42-25(3)32(34(35(45)46)47-36(4,5)6)33(31)44-18-15-37(7,8)16-19-44/h9-13,20,34H,14-19,21-22H2,1-8H3,(H,45,46)/t34-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324023
PNG
(US10189816, Compound 16)
Show SMILES Cc1ccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)cc1C(F)(F)F |r|
Show InChI InChI=1S/C38H48F3N3O3/c1-23-9-10-26(19-30(23)38(39,40)41)21-43-16-13-27-20-28(11-12-29(27)22-43)31-24(2)42-25(3)32(34(35(45)46)47-36(4,5)6)33(31)44-17-14-37(7,8)15-18-44/h9-12,19-20,34H,13-18,21-22H2,1-8H3,(H,45,46)/t34-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324024
PNG
(US10189816, Compound 161 | US10189816, Compound 17)
Show SMILES Cc1ccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)cc1C |r|
Show InChI InChI=1S/C38H51N3O3/c1-24-10-11-28(20-25(24)2)22-40-17-14-29-21-30(12-13-31(29)23-40)32-26(3)39-27(4)33(35(36(42)43)44-37(5,6)7)34(32)41-18-15-38(8,9)16-19-41/h10-13,20-21,35H,14-19,22-23H2,1-9H3,(H,42,43)/t35-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324025
PNG
(US10189816, Compound 18)
Show SMILES Cc1ccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)cc1F |r|
Show InChI InChI=1S/C37H48FN3O3/c1-23-9-10-26(19-30(23)38)21-40-16-13-27-20-28(11-12-29(27)22-40)31-24(2)39-25(3)32(34(35(42)43)44-36(4,5)6)33(31)41-17-14-37(7,8)15-18-41/h9-12,19-20,34H,13-18,21-22H2,1-8H3,(H,42,43)/t34-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324026
PNG
(US10189816, Compound 19)
Show SMILES Cc1ccc(CN2CCc3cc(ccc3C2)-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c2N2CCC(C)(C)CC2)c(C)c1 |r|
Show InChI InChI=1S/C38H51N3O3/c1-24-10-11-30(25(2)20-24)22-40-17-14-28-21-29(12-13-31(28)23-40)32-26(3)39-27(4)33(35(36(42)43)44-37(5,6)7)34(32)41-18-15-38(8,9)16-19-41/h10-13,20-21,35H,14-19,22-23H2,1-9H3,(H,42,43)/t35-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324027
PNG
(US10189816, Compound 20)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccc(F)cc4F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H45F2N3O3/c1-22-30(25-8-9-26-20-40(15-12-24(26)18-25)21-27-10-11-28(37)19-29(27)38)32(41-16-13-36(6,7)14-17-41)31(23(2)39-22)33(34(42)43)44-35(3,4)5/h8-11,18-19,33H,12-17,20-21H2,1-7H3,(H,42,43)/t33-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324028
PNG
(US10189816, Compound 21)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4cccc(F)c4F)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H45F2N3O3/c1-22-29(25-11-12-26-20-40(16-13-24(26)19-25)21-27-9-8-10-28(37)31(27)38)32(41-17-14-36(6,7)15-18-41)30(23(2)39-22)33(34(42)43)44-35(3,4)5/h8-12,19,33H,13-18,20-21H2,1-7H3,(H,42,43)/t33-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324029
PNG
(US10189816, Compound 22)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccc(Cl)c(F)c4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H45ClFN3O3/c1-22-30(26-9-10-27-21-40(15-12-25(27)19-26)20-24-8-11-28(37)29(38)18-24)32(41-16-13-36(6,7)14-17-41)31(23(2)39-22)33(34(42)43)44-35(3,4)5/h8-11,18-19,33H,12-17,20-21H2,1-7H3,(H,42,43)/t33-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324030
PNG
(US10189816, Compound 23)
Show SMILES Cc1cccc(Cl)c1CN1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1N1CCC(C)(C)CC1 |r|
Show InChI InChI=1S/C37H48ClN3O3/c1-23-10-9-11-30(38)29(23)22-40-17-14-26-20-27(12-13-28(26)21-40)31-24(2)39-25(3)32(34(35(42)43)44-36(4,5)6)33(31)41-18-15-37(7,8)16-19-41/h9-13,20,34H,14-19,21-22H2,1-8H3,(H,42,43)/t34-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM324031
PNG
(US10189816, Compound 24)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccc(F)c(Cl)c4)CCc3c2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H45ClFN3O3/c1-22-30(26-9-10-27-21-40(15-12-25(27)19-26)20-24-8-11-29(38)28(37)18-24)32(41-16-13-36(6,7)14-17-41)31(23(2)39-22)33(34(42)43)44-35(3,4)5/h8-11,18-19,33H,12-17,20-21H2,1-7H3,(H,42,43)/t33-/m0/s1
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n/an/an/an/a<100n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10189816 (2019)


BindingDB Entry DOI: 10.7270/Q23R0W0W
More data for this
Ligand-Target Pair
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