Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UDP-glucuronosyltransferase 1A8 (Homo sapiens (Human)) | BDBM50044561 (CHEMBL3222137) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 3.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toyama Chemical Co., Ltd. Curated by ChEMBL | Assay Description Substrate inhibition of human UGT1A8-mediated T-5224 hydroxyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC ... | Drug Metab Dispos 39: 803-13 (2011) Article DOI: 10.1124/dmd.110.037952 BindingDB Entry DOI: 10.7270/Q2W37Z2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
UDP-glucuronosyltransferase 1A8 (Homo sapiens (Human)) | BDBM50088502 (CHEBI:5970 | CHEMBL3527329) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Max Rubner-Institute Curated by ChEMBL | Assay Description Substrate inhibition of human recombinant UGT1A8 assessed as IRI-O-5-monoglucuronide formation incubated for 5 mins prior to UDPGA addition measured ... | Drug Metab Dispos 39: 610-6 (2011) Article DOI: 10.1124/dmd.110.033076 BindingDB Entry DOI: 10.7270/Q20V8FHC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
UDP-glucuronosyltransferase 1A8 (Homo sapiens (Human)) | BDBM50088502 (CHEBI:5970 | CHEMBL3527329) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Max Rubner-Institute Curated by ChEMBL | Assay Description Substrate inhibition of human recombinant UGT1A8 assessed as IRI-O-4'-monoglucuronide formation incubated for 5 mins prior to UDPGA addition measured... | Drug Metab Dispos 39: 610-6 (2011) Article DOI: 10.1124/dmd.110.033076 BindingDB Entry DOI: 10.7270/Q20V8FHC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
UDP-glucuronosyltransferase 1A8 (Homo sapiens (Human)) | BDBM50358252 (CHEMBL1922235) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 3.54E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant UGT1A8 after 10 mins in presence of UDPGA | Drug Metab Dispos 40: 276-82 (2012) Article DOI: 10.1124/dmd.111.042614 BindingDB Entry DOI: 10.7270/Q2G162JK | |||||||||||
More data for this Ligand-Target Pair |