Compile Data Set for Download or QSAR

Found 13 hits of ec50 for UniProtKB: P49288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melatonin receptor type 1C (Gallus gallus)	BDBM50472540 (CHEMBL12815) Show SMILES CCCC(=O)N[C@H]1Cc2cccc3ccc(OC)c(C1)c23 Show InChI InChI=1S/C18H21NO2/c1-3-5-17(20)19-14-10-13-7-4-6-12-8-9-16(21-2)15(11-14)18(12)13/h4,6-9,14H,3,5,10-11H2,1-2H3,(H,19,20)/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<0.0100	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50472541 (CHEMBL273888) Show SMILES CCC(=O)N[C@@H]1Cc2cccc3ccc(OC)c(C1)c23 Show InChI InChI=1S/C17H19NO2/c1-3-16(19)18-13-9-12-6-4-5-11-7-8-15(20-2)14(10-13)17(11)12/h4-8,13H,3,9-10H2,1-2H3,(H,18,19)/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<0.0100	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50472537 (CHEMBL12664) Show SMILES CCC(=O)N[C@H]1Cc2cccc3ccc(OC)c(C1)c23 Show InChI InChI=1S/C17H19NO2/c1-3-16(19)18-13-9-12-6-4-5-11-7-8-15(20-2)14(10-13)17(11)12/h4-8,13H,3,9-10H2,1-2H3,(H,18,19)/t13-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<0.0100	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50472538 (CHEMBL12418) Show SMILES CCCC(=O)N[C@@H]1Cc2cccc3ccc(OC)c(C1)c23 Show InChI InChI=1S/C18H21NO2/c1-3-5-17(20)19-14-10-13-7-4-6-12-8-9-16(21-2)15(11-14)18(12)13/h4,6-9,14H,3,5,10-11H2,1-2H3,(H,19,20)/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<0.0100	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50470187 (CHEMBL428882) Show SMILES COc1ccc2ccc(OC)c(CCNC(C)=O)c2c1 Show InChI InChI=1S/C16H19NO3/c1-11(18)17-9-8-14-15-10-13(19-2)6-4-12(15)5-7-16(14)20-3/h4-7,10H,8-9H2,1-3H3,(H,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0370	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50035179 (Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...) Show SMILES COc1ccc2cccc(CCNC(C)=O)c2c1 Show InChI InChI=1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50472539 (CHEMBL12545) Show SMILES COc1ccc2cccc3C[C@@H](Cc1c23)NC(C)=O Show InChI InChI=1S/C16H17NO2/c1-10(18)17-13-8-12-5-3-4-11-6-7-15(19-2)14(9-13)16(11)12/h3-7,13H,8-9H2,1-2H3,(H,17,18)/t13-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50470868 (CHEMBL12795) Show SMILES COc1ccc2cccc3CC(Cc1c23)NC(C)=O Show InChI InChI=1S/C16H17NO2/c1-10(18)17-13-8-12-5-3-4-11-6-7-15(19-2)14(9-13)16(11)12/h3-7,13H,8-9H2,1-2H3,(H,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50472536 (CHEMBL276607) Show SMILES CCCC(=O)NC1Cc2cccc3ccc(OC)c(C1)c23 Show InChI InChI=1S/C18H21NO2/c1-3-5-17(20)19-14-10-13-7-4-6-12-8-9-16(21-2)15(11-14)18(12)13/h4,6-9,14H,3,5,10-11H2,1-2H3,(H,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description The functional activity on melatonin receptor was evaluated by its potency to lighten the skin of Xenopus laevis tadpoles				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50470869 (CHEMBL12477) Show SMILES CCC(=O)NC1Cc2cccc3ccc(OC)c(C1)c23 Show InChI InChI=1S/C17H19NO2/c1-3-16(19)18-13-9-12-6-4-5-11-7-8-15(20-2)14(10-13)17(11)12/h4-8,13H,3,9-10H2,1-2H3,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50472534 (CHEMBL12661) Show SMILES COc1ccc2cccc3C[C@H](Cc1c23)NC(C)=O Show InChI InChI=1S/C16H17NO2/c1-10(18)17-13-8-12-5-3-4-11-6-7-15(19-2)14(9-13)16(11)12/h3-7,13H,8-9H2,1-2H3,(H,17,18)/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50472535 (CHEMBL12296) Show SMILES O=C(NCCc1cccc2ccccc12)C1CCC1 Show InChI InChI=1S/C17H19NO/c19-17(15-8-4-9-15)18-12-11-14-7-3-6-13-5-1-2-10-16(13)14/h1-3,5-7,10,15H,4,8-9,11-12H2,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
					More data for this Ligand-Target Pair