BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with Target = 'Melatonin receptor type 1C' and Ligand = 'BDBM9019'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description Effect of compound on Melatonin receptor in chicken brain in the presence of MnCl2				J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H
CNRS-BIOCIS Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description In vitro binding affinity against melatonin receptor using 2-[125I]iodomelatonin (0.05 nM) and chicken brain membranes				J Med Chem 39: 3089-95 (1996) Article DOI: 10.1021/jm960219h BindingDB Entry DOI: 10.7270/Q2736TNJ
CNRS-BIOCIS Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity towards melatonin receptor, determined in chicken brain membranes using [2-125I]melatonin				J Med Chem 41: 451-67 (1998) Article DOI: 10.1021/jm970246n BindingDB Entry DOI: 10.7270/Q2154KSH
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity towards melatonin receptor using 2-[125I]iodomelatonin as radioligand in chick brain membranes				Citation and Details BindingDB Entry DOI: 10.7270/Q2HQ422R
TBA					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity towards melatonin receptor was determined using 2-[125I]iodomelatonin as radioligand in chick brain membranes				Citation and Details BindingDB Entry DOI: 10.7270/Q2CZ39B1
TBA					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity towards melatonin receptor in chicken brain.				J Med Chem 39: 1797-805 (1996) Article DOI: 10.1021/jm9508189 BindingDB Entry DOI: 10.7270/Q29026HC
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity in chicken brain membranes by using [2-125I]melatonin in a competition radioligand binding assay				J Med Chem 38: 1132-9 (1995) Article DOI: 10.1021/jm00007a010 BindingDB Entry DOI: 10.7270/Q2HM5C6M
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nantong University Curated by ChEMBL					Assay Description Displacement of 2-[125I]iodomelatonin from chick brain melatonin receptor				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111847 BindingDB Entry DOI: 10.7270/Q2H70K32
Nantong University Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes				J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H
CNRS-BIOCIS Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.676	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand				J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4
Universit£ de Paris-Sud Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Inhibition of 2-[125I]- iodomelatonin from chicken brain melatonin receptors				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
Universit£ de Paris-Sud Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description Effect of compound on Melatonin receptor in chicken brain in the presence of GTP-gamma-S				J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H
CNRS-BIOCIS Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Xenopus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
King's College London Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 358: 522-8 (1998) Article DOI: 10.1007/pl00005288 BindingDB Entry DOI: 10.7270/Q2WW7G6S
King's College London Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Xenopus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
King's College Curated by PDSP K_i Database									Biol Cell 89: 531-7 (1997) Article DOI: 10.1016/s0248-4900(98)80009-9 BindingDB Entry DOI: 10.7270/Q2JS9P06
King's College Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Xenopus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0794	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Effect on pigment aggregation in Xenopus laevis melanophores				Bioorg Med Chem 15: 4543-51 (2007) Article DOI: 10.1016/j.bmc.2007.04.013 BindingDB Entry DOI: 10.7270/Q29026K8
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM9019 (CHEMBL45 \| Melatonin \| N-[2-(5-methoxy-1H-indol-3-...) Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skin				J Med Chem 42: 1100-5 (1999) Article DOI: 10.1021/jm9804937 BindingDB Entry DOI: 10.7270/Q28G8PDM
Universit£ de Paris-Sud Curated by ChEMBL					More data for this Ligand-Target Pair