Compile Data Set for Download or QSAR

Found 80 hits of ic50 for UniProtKB: P42582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50161047 (5-Methyl-3-phenyl-isoxazole-4-carboxylic acid (4-d...) Show SMILES CCN(CC)c1ccc(NC(=O)c2c(C)onc2-c2ccccc2)cc1 Show InChI InChI=1S/C21H23N3O2/c1-4-24(5-2)18-13-11-17(12-14-18)22-21(25)19-15(3)26-23-20(19)16-9-7-6-8-10-16/h6-14H,4-5H2,1-3H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249951 (CHEMBL4059969) Show SMILES CC(C)COC(=O)c1ccc(NC(=O)c2ccncc2)cc1 Show InChI InChI=1S/C17H18N2O3/c1-12(2)11-22-17(21)14-3-5-15(6-4-14)19-16(20)13-7-9-18-10-8-13/h3-10,12H,11H2,1-2H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249950 (CHEMBL4078483) Show SMILES CCOc1ccc(\C=C2/SC(=O)N(CC)C2=O)cc1 Show InChI InChI=1S/C14H15NO3S/c1-3-15-13(16)12(19-14(15)17)9-10-5-7-11(8-6-10)18-4-2/h5-9H,3-4H2,1-2H3/b12-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249881 (CHEMBL4099820) Show SMILES CCN(CC)c1ccc(\C=N\n2c(S)nnc2C2CCCCC2)cc1 Show InChI InChI=1S/C19H27N5S/c1-3-23(4-2)17-12-10-15(11-13-17)14-20-24-18(21-22-19(24)25)16-8-6-5-7-9-16/h10-14,16H,3-9H2,1-2H3,(H,22,25)/b20-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249967 (CHEMBL3196347) Show SMILES CCOc1ccc(\C=N\n2c(S)nnc2C2CCCCC2)cc1 Show InChI InChI=1S/C17H22N4OS/c1-2-22-15-10-8-13(9-11-15)12-18-21-16(19-20-17(21)23)14-6-4-3-5-7-14/h8-12,14H,2-7H2,1H3,(H,20,23)/b18-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249879 (CHEMBL4089681) Show SMILES CC(C)(C)c1ccc(\C=N\n2c(S)nnc2-c2ccncc2)cc1 Show InChI InChI=1S/C18H19N5S/c1-18(2,3)15-6-4-13(5-7-15)12-20-23-16(21-22-17(23)24)14-8-10-19-11-9-14/h4-12H,1-3H3,(H,22,24)/b20-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249880 (CHEMBL4061558) Show SMILES CN(C)c1ccc(\C=N\n2c(S)nnc2-c2ccncc2)cc1 Show InChI InChI=1S/C16H16N6S/c1-21(2)14-5-3-12(4-6-14)11-18-22-15(19-20-16(22)23)13-7-9-17-10-8-13/h3-11H,1-2H3,(H,20,23)/b18-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249874 (CHEMBL4076746) Show SMILES COc1cccc(\C=N\n2c(S)nnc2-c2ccccc2)c1OC Show InChI InChI=1S/C17H16N4O2S/c1-22-14-10-6-9-13(15(14)23-2)11-18-21-16(19-20-17(21)24)12-7-4-3-5-8-12/h3-11H,1-2H3,(H,20,24)/b18-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249836 (CHEMBL4095086) Show SMILES CCN1C(=O)S\C(=C/c2ccc(N3CCCC3)c(F)c2)C1=O Show InChI InChI=1S/C16H17FN2O2S/c1-2-19-15(20)14(22-16(19)21)10-11-5-6-13(12(17)9-11)18-7-3-4-8-18/h5-6,9-10H,2-4,7-8H2,1H3/b14-10-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249966 (CHEMBL4097402) Show SMILES CCOc1ccccc1\C=N\n1c(S)nnc1-c1ccccc1 Show InChI InChI=1S/C17H16N4OS/c1-2-22-15-11-7-6-10-14(15)12-18-21-16(19-20-17(21)23)13-8-4-3-5-9-13/h3-12H,2H2,1H3,(H,20,23)/b18-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249847 (CHEMBL4095473) Show SMILES CC(C)COC(=O)c1ccc(NC(=O)c2cccs2)cc1 Show InChI InChI=1S/C16H17NO3S/c1-11(2)10-20-16(19)12-5-7-13(8-6-12)17-15(18)14-4-3-9-21-14/h3-9,11H,10H2,1-2H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249873 (CHEMBL4103231) Show SMILES COc1ccc(\C=N\n2c(S)nnc2C2CCCCC2)cc1OCc1ccccc1 Show InChI InChI=1S/C23H26N4O2S/c1-28-20-13-12-18(14-21(20)29-16-17-8-4-2-5-9-17)15-24-27-22(25-26-23(27)30)19-10-6-3-7-11-19/h2,4-5,8-9,12-15,19H,3,6-7,10-11,16H2,1H3,(H,26,30)/b24-15+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249824 (CHEMBL4081879) Show SMILES CCCOc1ccc(\C=N\n2c(S)nnc2-c2ccncc2)cc1 Show InChI InChI=1S/C17H17N5OS/c1-2-11-23-15-5-3-13(4-6-15)12-19-22-16(20-21-17(22)24)14-7-9-18-10-8-14/h3-10,12H,2,11H2,1H3,(H,21,24)/b19-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249835 (CHEMBL4062678) Show SMILES CC(C)CCN1C(=O)S\C(=C/c2ccc(cc2)N(C)C)C1=O Show InChI InChI=1S/C17H22N2O2S/c1-12(2)9-10-19-16(20)15(22-17(19)21)11-13-5-7-14(8-6-13)18(3)4/h5-8,11-12H,9-10H2,1-4H3/b15-11-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249949 (CHEMBL4100136) Show SMILES Cc1onc(c1C(=O)Nc1ccc(OC(F)(F)F)cc1)-c1ccccc1 Show InChI InChI=1S/C18H13F3N2O3/c1-11-15(16(23-26-11)12-5-3-2-4-6-12)17(24)22-13-7-9-14(10-8-13)25-18(19,20)21/h2-10H,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249872 (CHEMBL4085301) Show SMILES COc1ccc(\C=N\n2c(S)nnc2-c2ccccc2)cc1C Show InChI InChI=1S/C17H16N4OS/c1-12-10-13(8-9-15(12)22-2)11-18-21-16(19-20-17(21)23)14-6-4-3-5-7-14/h3-11H,1-2H3,(H,20,23)/b18-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249870 (CHEMBL4086394) Show SMILES Sc1nnc(-c2ccccc2)n1\N=C\c1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C21H16N4OS/c27-21-24-23-20(17-9-3-1-4-10-17)25(21)22-15-16-8-7-13-19(14-16)26-18-11-5-2-6-12-18/h1-15H,(H,24,27)/b22-15+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249964 (CHEMBL1381879) Show SMILES CC(C)Oc1ccc(NC(=O)c2c(C)onc2-c2ccccc2)cc1 Show InChI InChI=1S/C20H20N2O3/c1-13(2)24-17-11-9-16(10-12-17)21-20(23)18-14(3)25-22-19(18)15-7-5-4-6-8-15/h4-13H,1-3H3,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249947 (CHEMBL4083694) Show SMILES CC(C)c1ccc(NC(=O)c2c(C)onc2-c2ccccc2)cc1 Show InChI InChI=1S/C20H20N2O2/c1-13(2)15-9-11-17(12-10-15)21-20(23)18-14(3)24-22-19(18)16-7-5-4-6-8-16/h4-13H,1-3H3,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249948 (CHEMBL4061938) Show SMILES Cc1onc(c1C(=O)Nc1ccc(C#N)c(Cl)c1)-c1ccccc1 Show InChI InChI=1S/C18H12ClN3O2/c1-11-16(17(22-24-11)12-5-3-2-4-6-12)18(23)21-14-8-7-13(10-20)15(19)9-14/h2-9H,1H3,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249946 (CHEMBL4070567) Show SMILES Cc1onc(c1C(=O)Nc1ccc2CCCc2c1)-c1ccccc1 Show InChI InChI=1S/C20H18N2O2/c1-13-18(19(22-24-13)15-6-3-2-4-7-15)20(23)21-17-11-10-14-8-5-9-16(14)12-17/h2-4,6-7,10-12H,5,8-9H2,1H3,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249976 (CHEMBL4073403) Show SMILES Cc1onc(c1C(=O)Nc1ccc(cc1)C(C)(C)C)-c1ccccc1 Show InChI InChI=1S/C21H22N2O2/c1-14-18(19(23-25-14)15-8-6-5-7-9-15)20(24)22-17-12-10-16(11-13-17)21(2,3)4/h5-13H,1-4H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249965 (CHEMBL4076019) Show SMILES CCN(CC)c1ccc(\C=N\n2c(S)nnc2-c2ccc(OC)cc2)cc1 Show InChI InChI=1S/C20H23N5OS/c1-4-24(5-2)17-10-6-15(7-11-17)14-21-25-19(22-23-20(25)27)16-8-12-18(26-3)13-9-16/h6-14H,4-5H2,1-3H3,(H,23,27)/b21-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249864 (CHEMBL4078535) Show SMILES Oc1c(CC=C)cccc1\C=N\n1c(S)nnc1-c1ccccc1 Show InChI InChI=1S/C18H16N4OS/c1-2-7-13-10-6-11-15(16(13)23)12-19-22-17(20-21-18(22)24)14-8-4-3-5-9-14/h2-6,8-12,23H,1,7H2,(H,21,24)/b19-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249904 (CHEMBL4098503) Show SMILES Cc1onc(c1C(=O)Nc1cccc(c1)S(=O)(=O)NCc1ccco1)-c1ccccc1 Show InChI InChI=1S/C22H19N3O5S/c1-15-20(21(25-30-15)16-7-3-2-4-8-16)22(26)24-17-9-5-11-19(13-17)31(27,28)23-14-18-10-6-12-29-18/h2-13,23H,14H2,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249945 (CHEMBL4081188) Show SMILES CCOc1ccc(NC(=O)c2c(C)onc2-c2ccccc2)cc1 Show InChI InChI=1S/C19H18N2O3/c1-3-23-16-11-9-15(10-12-16)20-19(22)17-13(2)24-21-18(17)14-7-5-4-6-8-14/h4-12H,3H2,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249952 (CHEMBL4090632) Show SMILES [O-][N+](=O)c1cccc(\C=C2/SC(=O)NC2=O)c1 Show InChI InChI=1S/C10H6N2O4S/c13-9-8(17-10(14)11-9)5-6-2-1-3-7(4-6)12(15)16/h1-5H,(H,11,13,14)/b8-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249903 (CHEMBL4080486) Show SMILES CCC(C)c1ccc(NC(=O)c2c(C)onc2-c2ccccc2Cl)cc1 Show InChI InChI=1S/C21H21ClN2O2/c1-4-13(2)15-9-11-16(12-10-15)23-21(25)19-14(3)26-24-20(19)17-7-5-6-8-18(17)22/h5-13H,4H2,1-3H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249944 (CHEMBL4099211) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)c2c(C)onc2-c2ccccc2)cc1 Show InChI InChI=1S/C21H20N2O4/c1-13(2)26-21(25)16-9-11-17(12-10-16)22-20(24)18-14(3)27-23-19(18)15-7-5-4-6-8-15/h4-13H,1-3H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249905 (CHEMBL1571383) Show SMILES Cc1onc(c1C(=O)Nc1ccc(cc1)-c1nnc2CCCCCn12)-c1ccccc1 Show InChI InChI=1S/C24H23N5O2/c1-16-21(22(28-31-16)17-8-4-2-5-9-17)24(30)25-19-13-11-18(12-14-19)23-27-26-20-10-6-3-7-15-29(20)23/h2,4-5,8-9,11-14H,3,6-7,10,15H2,1H3,(H,25,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249975 (CHEMBL4076171) Show SMILES Cc1onc(c1C(=O)Nc1cccc(c1)C(=O)NC1CC1)-c1ccccc1 Show InChI InChI=1S/C21H19N3O3/c1-13-18(19(24-27-13)14-6-3-2-4-7-14)21(26)23-17-9-5-8-15(12-17)20(25)22-16-10-11-16/h2-9,12,16H,10-11H2,1H3,(H,22,25)(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249828 (CHEMBL493742) Show SMILES CCc1ccc(\C=C2/SC(=O)NC2=O)cc1 Show InChI InChI=1S/C12H11NO2S/c1-2-8-3-5-9(6-4-8)7-10-11(14)13-12(15)16-10/h3-7H,2H2,1H3,(H,13,14,15)/b10-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249974 (CHEMBL4090787) Show SMILES Cc1onc(c1C(=O)Nc1ccc(cc1)C(C)(C)C)-c1ccccc1Cl Show InChI InChI=1S/C21H21ClN2O2/c1-13-18(19(24-26-13)16-7-5-6-8-17(16)22)20(25)23-15-11-9-14(10-12-15)21(2,3)4/h5-12H,1-4H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM7459 (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...) Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249960 (CHEMBL4068091) Show SMILES CC(C)CNC(=O)c1ccc(NC(=O)C2CC2)cc1 Show InChI InChI=1S/C15H20N2O2/c1-10(2)9-16-14(18)11-5-7-13(8-6-11)17-15(19)12-3-4-12/h5-8,10,12H,3-4,9H2,1-2H3,(H,16,18)(H,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249902 (CHEMBL4069789) Show SMILES Cc1onc(c1C(=O)Nc1ccc2OC3(CCCC3)Oc2c1)-c1ccccc1 Show InChI InChI=1S/C22H20N2O4/c1-14-19(20(24-28-14)15-7-3-2-4-8-15)21(25)23-16-9-10-17-18(13-16)27-22(26-17)11-5-6-12-22/h2-4,7-10,13H,5-6,11-12H2,1H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM7458 (5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...) Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)cc2o1 Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249863 (CHEMBL3193145) Show SMILES COc1ccc(\C=N\n2c(SC)nnc2-c2ccccc2)cc1C Show InChI InChI=1S/C18H18N4OS/c1-13-11-14(9-10-16(13)23-2)12-19-22-17(20-21-18(22)24-3)15-7-5-4-6-8-15/h4-12H,1-3H3/b19-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249827 (CHEMBL4060038) Show SMILES CCOc1ccc(\C=C2/SC(=O)N(CC)C2=O)cc1OCC Show InChI InChI=1S/C16H19NO4S/c1-4-17-15(18)14(22-16(17)19)10-11-7-8-12(20-5-2)13(9-11)21-6-3/h7-10H,4-6H2,1-3H3/b14-10-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249972 (CHEMBL4096074) Show SMILES Cc1onc(c1C(=O)Nc1cccc(c1)S(=O)(=O)NC1=NC=CC1)-c1ccccc1 |c:23,t:21| Show InChI InChI=1S/C21H18N4O4S/c1-14-19(20(24-29-14)15-7-3-2-4-8-15)21(26)23-16-9-5-10-17(13-16)30(27,28)25-18-11-6-12-22-18/h2-10,12-13H,11H2,1H3,(H,22,25)(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249901 (CHEMBL4068769) Show SMILES Cc1onc(c1C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1)-c1ccccc1 Show InChI InChI=1S/C21H17N5O4S/c1-14-18(19(25-30-14)15-6-3-2-4-7-15)20(27)24-16-8-10-17(11-9-16)31(28,29)26-21-22-12-5-13-23-21/h2-13H,1H3,(H,24,27)(H,22,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249862 (CHEMBL3211162) Show SMILES CCOc1ccc(\C=N\n2c(SC)nnc2-c2ccccc2)cc1OCC Show InChI InChI=1S/C20H22N4O2S/c1-4-25-17-12-11-15(13-18(17)26-5-2)14-21-24-19(22-23-20(24)27-3)16-9-7-6-8-10-16/h6-14H,4-5H2,1-3H3/b21-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249963 (CHEMBL4067647) Show SMILES CC(C)(C)c1ccc(\C=N\n2c(S)nnc2-c2cccnc2)cc1 Show InChI InChI=1S/C18H19N5S/c1-18(2,3)15-8-6-13(7-9-15)11-20-23-16(21-22-17(23)24)14-5-4-10-19-12-14/h4-12H,1-3H3,(H,22,24)/b20-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249900 (CHEMBL4060110) Show SMILES CCC(C)c1ccc(NC(=O)c2c(C)onc2-c2ccccc2)cc1 Show InChI InChI=1S/C21H22N2O2/c1-4-14(2)16-10-12-18(13-11-16)22-21(24)19-15(3)25-23-20(19)17-8-6-5-7-9-17/h5-14H,4H2,1-3H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249899 (CHEMBL4088348) Show SMILES Cc1onc(c1C(=O)Nc1cccc(c1)S(=O)(=O)N1CCCC1)-c1ccccc1 Show InChI InChI=1S/C21H21N3O4S/c1-15-19(20(23-28-15)16-8-3-2-4-9-16)21(25)22-17-10-7-11-18(14-17)29(26,27)24-12-5-6-13-24/h2-4,7-11,14H,5-6,12-13H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249861 (CHEMBL4105226) Show SMILES Sc1nnc(-c2ccccc2)n1\N=C\c1ccc(OC2CCCC2)cc1 Show InChI InChI=1S/C20H20N4OS/c26-20-23-22-19(16-6-2-1-3-7-16)24(20)21-14-15-10-12-18(13-11-15)25-17-8-4-5-9-17/h1-3,6-7,10-14,17H,4-5,8-9H2,(H,23,26)/b21-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249846 (CHEMBL4103229) Show SMILES CC(C)COC(=O)c1ccc(NC(=O)CCC(O)=O)cc1 Show InChI InChI=1S/C15H19NO5/c1-10(2)9-21-15(20)11-3-5-12(6-4-11)16-13(17)7-8-14(18)19/h3-6,10H,7-9H2,1-2H3,(H,16,17)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249898 (CHEMBL1348312) Show SMILES Cc1onc(c1C(=O)Nc1ccc(cc1)N1CCOCC1)-c1ccccc1Cl Show InChI InChI=1S/C21H20ClN3O3/c1-14-19(20(24-28-14)17-4-2-3-5-18(17)22)21(26)23-15-6-8-16(9-7-15)25-10-12-27-13-11-25/h2-9H,10-13H2,1H3,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249845 (CHEMBL4078962) Show SMILES CC(C)CNC(=O)c1ccc(NC(=O)C(F)(F)F)cc1 Show InChI InChI=1S/C13H15F3N2O2/c1-8(2)7-17-11(19)9-3-5-10(6-4-9)18-12(20)13(14,15)16/h3-6,8H,7H2,1-2H3,(H,17,19)(H,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249971 (CHEMBL4091690) Show SMILES Cc1onc(c1C(=O)Nc1ccc(Oc2ccccc2)cc1)-c1ccccc1 Show InChI InChI=1S/C23H18N2O3/c1-16-21(22(25-28-16)17-8-4-2-5-9-17)23(26)24-18-12-14-20(15-13-18)27-19-10-6-3-7-11-19/h2-15H,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
					More data for this Ligand-Target Pair

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