Compile Data Set for Download or QSAR

Found 4 hits of ic50 for UniProtKB: P07437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Homo sapiens)	BDBM50274078 (CHEMBL4128424) Show SMILES Clc1ccc(cc1)C1SCC(=O)N1NC(=O)COc1ccc2c(cc(=O)oc2c1)-c1ccccc1 Show InChI InChI=1S/C26H19ClN2O5S/c27-18-8-6-17(7-9-18)26-29(24(31)15-35-26)28-23(30)14-33-19-10-11-20-21(16-4-2-1-3-5-16)13-25(32)34-22(20)12-19/h1-13,26H,14-15H2,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre Curated by ChEMBL					Assay Description Inhibition of tubulin beta polymerization in human MCF7 cells after 18 to 24 hrs by ELISA based spectrophotometric analysis				Bioorg Med Chem 26: 3474-3490 (2018) Article DOI: 10.1016/j.bmc.2018.05.022 BindingDB Entry DOI: 10.7270/Q2J38W3R
					More data for this Ligand-Target Pair
Tubulin beta chain (Homo sapiens)	BDBM50274079 (CHEMBL4127437) Show SMILES COc1cc(cc(OC)c1OC)C1SCC(=O)N1NC(=O)COc1ccc2c(cc(=O)oc2c1)-c1ccccc1 Show InChI InChI=1S/C29H26N2O8S/c1-35-23-11-18(12-24(36-2)28(23)37-3)29-31(26(33)16-40-29)30-25(32)15-38-19-9-10-20-21(17-7-5-4-6-8-17)14-27(34)39-22(20)13-19/h4-14,29H,15-16H2,1-3H3,(H,30,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre Curated by ChEMBL					Assay Description Inhibition of tubulin beta polymerization in human MCF7 cells after 18 to 24 hrs by ELISA based spectrophotometric analysis				Bioorg Med Chem 26: 3474-3490 (2018) Article DOI: 10.1016/j.bmc.2018.05.022 BindingDB Entry DOI: 10.7270/Q2J38W3R
					More data for this Ligand-Target Pair
Tubulin beta chain (Homo sapiens)	BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) Show SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	6.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre Curated by ChEMBL					Assay Description Inhibition of tubulin beta polymerization in human MCF7 cells after 18 to 24 hrs by ELISA based spectrophotometric analysis				Bioorg Med Chem 26: 3474-3490 (2018) Article DOI: 10.1016/j.bmc.2018.05.022 BindingDB Entry DOI: 10.7270/Q2J38W3R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin beta chain (Homo sapiens)	BDBM50274080 (CHEMBL4129198) Show SMILES Fc1ccc(cc1)C1SCC(=O)N1NC(=O)COc1ccc2c(cc(=O)oc2c1)-c1ccccc1 Show InChI InChI=1S/C26H19FN2O5S/c27-18-8-6-17(7-9-18)26-29(24(31)15-35-26)28-23(30)14-33-19-10-11-20-21(16-4-2-1-3-5-16)13-25(32)34-22(20)12-19/h1-13,26H,14-15H2,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre Curated by ChEMBL					Assay Description Inhibition of tubulin beta polymerization in human MCF7 cells after 18 to 24 hrs by ELISA based spectrophotometric analysis				Bioorg Med Chem 26: 3474-3490 (2018) Article DOI: 10.1016/j.bmc.2018.05.022 BindingDB Entry DOI: 10.7270/Q2J38W3R
					More data for this Ligand-Target Pair