Compile Data Set for Download or QSAR

Found 11 hits of ec50 for UniProtKB: P19357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510635 (CHEMBL4452486) Show SMILES CC(C)(C)OC(=O)NCCOCCOc1ccccc1-c1nnc(Nc2ccc(CC(N)=O)cc2F)c2ccsc12 Show InChI InChI=1S/C29H32FN5O5S/c1-29(2,3)40-28(37)32-11-12-38-13-14-39-23-7-5-4-6-19(23)25-26-20(10-15-41-26)27(35-34-25)33-22-9-8-18(16-21(22)30)17-24(31)36/h4-10,15-16H,11-14,17H2,1-3H3,(H2,31,36)(H,32,37)(H,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510640 (CHEMBL4529010) Show SMILES CC(C)(C)OC(=O)NCCCCOc1ccccc1-c1nnc(Nc2ccc(CC(N)=O)cc2F)c2ccsc12 Show InChI InChI=1S/C29H32FN5O4S/c1-29(2,3)39-28(37)32-13-6-7-14-38-23-9-5-4-8-19(23)25-26-20(12-15-40-26)27(35-34-25)33-22-11-10-18(16-21(22)30)17-24(31)36/h4-5,8-12,15-16H,6-7,13-14,17H2,1-3H3,(H2,31,36)(H,32,37)(H,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510638 (CHEMBL4469586) Show SMILES NC(=O)Cc1ccc(Nc2nnc(-c3ccccc3OCC3COCCO3)c3sccc23)c(F)c1 Show InChI InChI=1S/C25H23FN4O4S/c26-19-11-15(12-22(27)31)5-6-20(19)28-25-18-7-10-35-24(18)23(29-30-25)17-3-1-2-4-21(17)34-14-16-13-32-8-9-33-16/h1-7,10-11,16H,8-9,12-14H2,(H2,27,31)(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510632 (CHEMBL4550275) Show SMILES NC(=O)Cc1ccc(Nc2nnc(-c3ccccc3OCc3cscn3)c3sccc23)c(F)c1 Show InChI InChI=1S/C24H18FN5O2S2/c25-18-9-14(10-21(26)31)5-6-19(18)28-24-17-7-8-34-23(17)22(29-30-24)16-3-1-2-4-20(16)32-11-15-12-33-13-27-15/h1-9,12-13H,10-11H2,(H2,26,31)(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510636 (CHEMBL4539293) Show SMILES CC(C)(C)NC(=O)NCCOCCOc1ccccc1-c1nnc(Nc2ccc(CC(N)=O)cc2F)c2ccsc12 Show InChI InChI=1S/C29H33FN6O4S/c1-29(2,3)34-28(38)32-11-12-39-13-14-40-23-7-5-4-6-19(23)25-26-20(10-15-41-26)27(36-35-25)33-22-9-8-18(16-21(22)30)17-24(31)37/h4-10,15-16H,11-14,17H2,1-3H3,(H2,31,37)(H,33,36)(H2,32,34,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510637 (CHEMBL4466592) Show SMILES NC(=O)Cc1ccc(Nc2nnc(-c3ccccc3OCc3ccccn3)c3sccc23)c(F)c1 Show InChI InChI=1S/C26H20FN5O2S/c27-20-13-16(14-23(28)33)8-9-21(20)30-26-19-10-12-35-25(19)24(31-32-26)18-6-1-2-7-22(18)34-15-17-5-3-4-11-29-17/h1-13H,14-15H2,(H2,28,33)(H,30,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510639 (CHEMBL4588796) Show SMILES COCCOc1ccccc1-c1nnc(Nc2ccc(CC(N)=O)cc2F)c2ccsc12 Show InChI InChI=1S/C23H21FN4O3S/c1-30-9-10-31-19-5-3-2-4-15(19)21-22-16(8-11-32-22)23(28-27-21)26-18-7-6-14(12-17(18)24)13-20(25)29/h2-8,11-12H,9-10,13H2,1H3,(H2,25,29)(H,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510641 (CHEMBL4435909) Show SMILES CCOC(=O)NCCCCOc1ccccc1-c1nnc(Nc2ccc(CC(N)=O)cc2F)c2ccsc12 Show InChI InChI=1S/C27H28FN5O4S/c1-2-36-27(35)30-12-5-6-13-37-22-8-4-3-7-18(22)24-25-19(11-14-38-25)26(33-32-24)31-21-10-9-17(15-20(21)28)16-23(29)34/h3-4,7-11,14-15H,2,5-6,12-13,16H2,1H3,(H2,29,34)(H,30,35)(H,31,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510634 (CHEMBL4570366) Show SMILES COCCOCCOc1ccccc1-c1nnc(Nc2ccc(CC(N)=O)cc2F)c2ccsc12 Show InChI InChI=1S/C25H25FN4O4S/c1-32-9-10-33-11-12-34-21-5-3-2-4-17(21)23-24-18(8-13-35-24)25(30-29-23)28-20-7-6-16(14-19(20)26)15-22(27)31/h2-8,13-14H,9-12,15H2,1H3,(H2,27,31)(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510633 (CHEMBL4439282) Show SMILES COc1ccccc1-c1nnc(Nc2ccc(CC(N)=O)cc2F)c2ccsc12 Show InChI InChI=1S/C21H17FN4O2S/c1-28-17-5-3-2-4-13(17)19-20-14(8-9-29-20)21(26-25-19)24-16-7-6-12(10-15(16)22)11-18(23)27/h2-10H,11H2,1H3,(H2,23,27)(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 4 (Rattus norvegicus)	BDBM50510631 (CHEMBL4576794) Show SMILES COc1ccccc1-c1nnc(Nc2ccc(CC(N)=O)cc2)c2CCCc12 Show InChI InChI=1S/C22H22N4O2/c1-28-19-8-3-2-5-18(19)21-16-6-4-7-17(16)22(26-25-21)24-15-11-9-14(10-12-15)13-20(23)27/h2-3,5,8-12H,4,6-7,13H2,1H3,(H2,23,27)(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Induction of GLUT4 translocation in rat L6-GLUT4myc differentiated myotube cells after 20 mins by chemiluminescent method				Bioorg Med Chem Lett 29: 1785-1790 (2019) Article DOI: 10.1016/j.bmcl.2019.05.013 BindingDB Entry DOI: 10.7270/Q2FR00XB
					More data for this Ligand-Target Pair