Compile Data Set for Download or QSAR

Found 6 hits of ic50 for UniProtKB: E9PU00   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel, subfamily V, member 3 (Rattus norvegicus)	BDBM50463447 (CHEMBL4249046) Show SMILES [H][C@]12Cc3c(O)cc(CCCCC)cc3O[C@@]1(C)CCCC2(C)C |r| Show InChI InChI=1S/C21H32O2/c1-5-6-7-9-15-12-17(22)16-14-19-20(2,3)10-8-11-21(19,4)23-18(16)13-15/h12-13,19,22H,5-11,14H2,1-4H3/t19-,21+/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel, subfamily V, member 3 (Rattus norvegicus)	BDBM50463445 (CHEMBL4238545) Show SMILES CCCCCc1cc2O[C@]3(Cc2c(O)c1)[C@@H](C)CCCC3(C)C |r| Show InChI InChI=1S/C21H32O2/c1-5-6-7-10-16-12-18(22)17-14-21(23-19(17)13-16)15(2)9-8-11-20(21,3)4/h12-13,15,22H,5-11,14H2,1-4H3/t15-,21+/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel, subfamily V, member 3 (Rattus norvegicus)	BDBM50463446 (CHEMBL4244422) Show SMILES [H][C@]12Cc3c(O)cc(CCCCC)cc3O[C@]1(C)CCCC2(C)C |r| Show InChI InChI=1S/C21H32O2/c1-5-6-7-9-15-12-17(22)16-14-19-20(2,3)10-8-11-21(19,4)23-18(16)13-15/h12-13,19,22H,5-11,14H2,1-4H3/t19-,21-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel, subfamily V, member 3 (Rattus norvegicus)	BDBM50463444 (CHEMBL4238978) Show SMILES [H][C@]12Cc3c(O)cc(CCCCC)cc3O[C@]1(C)CC[C@@H](I)C2(C)C |r| Show InChI InChI=1S/C21H31IO2/c1-5-6-7-8-14-11-16(23)15-13-18-20(2,3)19(22)9-10-21(18,4)24-17(15)12-14/h11-12,18-19,23H,5-10,13H2,1-4H3/t18-,19-,21-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel, subfamily V, member 3 (Rattus norvegicus)	BDBM50463442 (CHEMBL4242719) Show SMILES CCCCCc1cc2O[C@]3(Cc2c(O)c1)[C@H](C)CCCC3(C)C |r| Show InChI InChI=1S/C21H32O2/c1-5-6-7-10-16-12-18(22)17-14-21(23-19(17)13-16)15(2)9-8-11-20(21,3)4/h12-13,15,22H,5-11,14H2,1-4H3/t15-,21-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel, subfamily V, member 3 (Rattus norvegicus)	BDBM50463443 (CHEMBL4241477) Show SMILES CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1 Show InChI InChI=1S/C28H40O2/c1-6-7-8-10-22-19-25(29)24-15-18-28(5,30-26(24)20-22)17-9-16-27(3,4)23-13-11-21(2)12-14-23/h11-14,19-20,29H,6-10,15-18H2,1-5H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair