null

SMILES: CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1

InChI Key: InChIKey=HVACNJHBAXOENX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50463443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50463443 (CHEMBL4241477) Show SMILES CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1 Show InChI InChI=1S/C28H40O2/c1-6-7-8-10-22-19-25(29)24-15-18-28(5,30-26(24)20-22)17-9-16-27(3,4)23-13-11-21(2)12-14-23/h11-14,19-20,29H,6-10,15-18H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced increase in intracellular calcium level pret...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 2 (Rattus norvegicus)	BDBM50463443 (CHEMBL4241477) Show SMILES CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1 Show InChI InChI=1S/C28H40O2/c1-6-7-8-10-22-19-25(29)24-15-18-28(5,30-26(24)20-22)17-9-16-27(3,4)23-13-11-21(2)12-14-23/h11-14,19-20,29H,6-10,15-18H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced increase in intracellular calcium level pretreated f...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat))	BDBM50463443 (CHEMBL4241477) Show SMILES CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1 Show InChI InChI=1S/C28H40O2/c1-6-7-8-10-22-19-25(29)24-15-18-28(5,30-26(24)20-22)17-9-16-27(3,4)23-13-11-21(2)12-14-23/h11-14,19-20,29H,6-10,15-18H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular calcium level pretreate...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50463443 (CHEMBL4241477) Show SMILES CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1 Show InChI InChI=1S/C28H40O2/c1-6-7-8-10-22-19-25(29)24-15-18-28(5,30-26(24)20-22)17-9-16-27(3,4)23-13-11-21(2)12-14-23/h11-14,19-20,29H,6-10,15-18H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Agonist activity at rat TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus)	BDBM50463443 (CHEMBL4241477) Show SMILES CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1 Show InChI InChI=1S/C28H40O2/c1-6-7-8-10-22-19-25(29)24-15-18-28(5,30-26(24)20-22)17-9-16-27(3,4)23-13-11-21(2)12-14-23/h11-14,19-20,29H,6-10,15-18H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by fluo-4-AM dye based fluorescence assay				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel, subfamily V, member 3 (Rattus norvegicus)	BDBM50463443 (CHEMBL4241477) Show SMILES CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1 Show InChI InChI=1S/C28H40O2/c1-6-7-8-10-22-19-25(29)24-15-18-28(5,30-26(24)20-22)17-9-16-27(3,4)23-13-11-21(2)12-14-23/h11-14,19-20,29H,6-10,15-18H2,1-5H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus)	BDBM50463443 (CHEMBL4241477) Show SMILES CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1 Show InChI InChI=1S/C28H40O2/c1-6-7-8-10-22-19-25(29)24-15-18-28(5,30-26(24)20-22)17-9-16-27(3,4)23-13-11-21(2)12-14-23/h11-14,19-20,29H,6-10,15-18H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular calcium level pretreated ...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50463443 (CHEMBL4241477) Show SMILES CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1 Show InChI InChI=1S/C28H40O2/c1-6-7-8-10-22-19-25(29)24-15-18-28(5,30-26(24)20-22)17-9-16-27(3,4)23-13-11-21(2)12-14-23/h11-14,19-20,29H,6-10,15-18H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular calcium level pret...				Bioorg Med Chem 26: 4532-4536 (2018) Article DOI: 10.1016/j.bmc.2018.07.044 BindingDB Entry DOI: 10.7270/Q2M32ZFD
					More data for this Ligand-Target Pair