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Compile Data Set for Download or QSAR

Found 3 hits of ki for UniProtKB: P0A0H2   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
rRNA adenine N-6-methyltransferase


(Staphylococcus aureus (strain N315))
BDBM50291836
PNG
(CHEMBL4177311)
Show SMILES FC(F)(F)c1ccc(nc1)N1CCN(CC1)C(=O)c1csc(Nc2ncccn2)n1
Show InChI InChI=1S/C18H16F3N7OS/c19-18(20,21)12-2-3-14(24-10-12)27-6-8-28(9-7-27)15(29)13-11-30-17(25-13)26-16-22-4-1-5-23-16/h1-5,10-11H,6-9H2,(H,22,23,25,26)
UniProtKB/SwissProt

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UniChem

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Article
PubMed
1.11E+5n/an/an/an/an/an/an/an/a



International Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Competitive inhibition of bacterial C-terminal His6-tagged ErmC' expressed in Escherichia coli BL21(DE3) in presence of [methyl-3H]SAM


Eur J Med Chem 146: 60-67 (2018)


Article DOI: 10.1016/j.ejmech.2017.11.032
BindingDB Entry DOI: 10.7270/Q2P55R2F
More data for this
Ligand-Target Pair
rRNA adenine N-6-methyltransferase


(Staphylococcus aureus (strain N315))
BDBM50291837
PNG
(CHEMBL4172068)
Show SMILES FC(F)(F)c1ccc(nc1)N1CCN(CC1)C(=O)c1c[nH]c(=O)[nH]1
Show InChI InChI=1S/C14H14F3N5O2/c15-14(16,17)9-1-2-11(18-7-9)21-3-5-22(6-4-21)12(23)10-8-19-13(24)20-10/h1-2,7-8H,3-6H2,(H2,19,20,24)
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PubMed
1.48E+5n/an/an/an/an/an/an/an/a



International Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...


Eur J Med Chem 146: 60-67 (2018)


Article DOI: 10.1016/j.ejmech.2017.11.032
BindingDB Entry DOI: 10.7270/Q2P55R2F
More data for this
Ligand-Target Pair
rRNA adenine N-6-methyltransferase


(Staphylococcus aureus (strain N315))
BDBM50291835
PNG
(CHEMBL4098242)
Show SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cccc(O)c2)n1
Show InChI InChI=1S/C15H14N4O2S2/c1-8-13(23-15(16-8)17-9(2)20)12-7-22-14(19-12)18-10-4-3-5-11(21)6-10/h3-7,21H,1-2H3,(H,18,19)(H,16,17,20)
UniProtKB/SwissProt

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UniChem

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Article
PubMed
3.54E+5n/an/an/an/an/an/an/an/a



International Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Competitive inhibition of bacterial C-terminal His6-tagged ErmC' expressed in Escherichia coli BL21(DE3) in presence of [methyl-3H]SAM


Eur J Med Chem 146: 60-67 (2018)


Article DOI: 10.1016/j.ejmech.2017.11.032
BindingDB Entry DOI: 10.7270/Q2P55R2F
More data for this
Ligand-Target Pair