Compile Data Set for Download or QSAR

Found 9 hits of ic50 for UniProtKB: P54493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460516 (CHEMBL4227539) Show SMILES Clc1cccc2c1nc(OCc1ccccc1)oc2=O Show InChI InChI=1S/C15H10ClNO3/c16-12-8-4-7-11-13(12)17-15(20-14(11)18)19-9-10-5-2-1-3-6-10/h1-8H,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460510 (CHEMBL4225584) Show SMILES Clc1cccc2nc(OCc3ccccc3)oc(=O)c12 Show InChI InChI=1S/C15H10ClNO3/c16-11-7-4-8-12-13(11)14(18)20-15(17-12)19-9-10-5-2-1-3-6-10/h1-8H,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460511 (CHEMBL4225103) Show SMILES Cc1cccc2nc(OCC#C)oc(=O)c12 Show InChI InChI=1S/C12H9NO3/c1-3-7-15-12-13-9-6-4-5-8(2)10(9)11(14)16-12/h1,4-6H,7H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50406296 (CHEMBL145012) Show SMILES O=c1oc(OCc2ccccc2)nc2ccccc12 Show InChI InChI=1S/C15H11NO3/c17-14-12-8-4-5-9-13(12)16-15(19-14)18-10-11-6-2-1-3-7-11/h1-9H,10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460512 (CHEMBL4225312) Show SMILES Cc1ccc2nc(OCc3ccccc3)oc(=O)c2c1 Show InChI InChI=1S/C16H13NO3/c1-11-7-8-14-13(9-11)15(18)20-16(17-14)19-10-12-5-3-2-4-6-12/h2-9H,10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460514 (CHEMBL4229256) Show SMILES Clc1cccc2nc(OCC#C)oc(=O)c12 Show InChI InChI=1S/C11H6ClNO3/c1-2-6-15-11-13-8-5-3-4-7(12)9(8)10(14)16-11/h1,3-5H,6H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50288096 (5-Chloro-2-ethoxy-benzo[d][1,3]oxazin-4-one | CHEM...) Show SMILES CCOc1nc2cccc(Cl)c2c(=O)o1 Show InChI InChI=1S/C10H8ClNO3/c1-2-14-10-12-7-5-3-4-6(11)8(7)9(13)15-10/h3-5H,2H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460513 (CHEMBL4228380) Show SMILES O=c1oc(OCc2ccccc2)nc2cc3ccccc3cc12 Show InChI InChI=1S/C19H13NO3/c21-18-16-10-14-8-4-5-9-15(14)11-17(16)20-19(23-18)22-12-13-6-2-1-3-7-13/h1-11H,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
					More data for this Ligand-Target Pair
Rhomboid protease GluP (Bacillus subtilis (strain 168))	BDBM50460515 (CHEMBL4229280) Show SMILES Cc1cccc2nc(OCc3ccccc3)oc(=O)c12 Show InChI InChI=1S/C16H13NO3/c1-11-6-5-9-13-14(11)15(18)20-16(17-13)19-10-12-7-3-2-4-8-12/h2-9H,10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...				Bioorg Med Chem Lett 28: 1423-1427 (2018) Article DOI: 10.1016/j.bmcl.2017.12.056 BindingDB Entry DOI: 10.7270/Q2WH2SM6
					More data for this Ligand-Target Pair