Found 5 hits of ic50 data for polymerid = 5327 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Poly(A)-specific ribonuclease PARN
(Homo sapiens (Human)) | BDBM50119716
(CHEMBL3616525)Show InChI InChI=1S/C18H23N5O3/c1-20(2)10-6-11-22-16-15(17(24)23(26)18(22)25)21(13-19-16)12-9-14-7-4-3-5-8-14/h3-5,7-8,13,26H,6,9-12H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Inhibition of PARN (unknown origin) |
Bioorg Med Chem Lett 25: 4219-24 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.095 BindingDB Entry DOI: 10.7270/Q2BV7JFF |
More data for this Ligand-Target Pair | |
Poly(A)-specific ribonuclease PARN
(Homo sapiens (Human)) | BDBM50119651
(CHEMBL3616505)Show InChI InChI=1S/C12H10N4O3/c17-11-9-10(14-12(18)16(11)19)13-7-15(9)6-8-4-2-1-3-5-8/h1-5,7,19H,6H2,(H,14,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Inhibition of PARN (unknown origin) |
Bioorg Med Chem Lett 25: 4219-24 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.095 BindingDB Entry DOI: 10.7270/Q2BV7JFF |
More data for this Ligand-Target Pair | |
Poly(A)-specific ribonuclease PARN
(Homo sapiens (Human)) | BDBM50119654
(CHEMBL3616507)Show InChI InChI=1S/C11H9N5O3/c17-10-8-9(14-11(18)16(10)19)13-6-15(8)5-7-3-1-2-4-12-7/h1-4,6,19H,5H2,(H,14,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.19E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Inhibition of PARN (unknown origin) |
Bioorg Med Chem Lett 25: 4219-24 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.095 BindingDB Entry DOI: 10.7270/Q2BV7JFF |
More data for this Ligand-Target Pair | |
Poly(A)-specific ribonuclease PARN
(Homo sapiens (Human)) | BDBM50119655
(CHEMBL3616508)Show InChI InChI=1S/C11H9N5O3/c17-10-8-9(14-11(18)16(10)19)13-6-15(8)5-7-2-1-3-12-4-7/h1-4,6,19H,5H2,(H,14,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Inhibition of PARN (unknown origin) |
Bioorg Med Chem Lett 25: 4219-24 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.095 BindingDB Entry DOI: 10.7270/Q2BV7JFF |
More data for this Ligand-Target Pair | |
Poly(A)-specific ribonuclease PARN
(Homo sapiens (Human)) | BDBM50119656
(CHEMBL3616509)Show InChI InChI=1S/C11H9N5O3/c17-10-8-9(14-11(18)16(10)19)13-6-15(8)5-7-1-3-12-4-2-7/h1-4,6,19H,5H2,(H,14,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.45E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Inhibition of PARN (unknown origin) |
Bioorg Med Chem Lett 25: 4219-24 (2015)
Article DOI: 10.1016/j.bmcl.2015.07.095 BindingDB Entry DOI: 10.7270/Q2BV7JFF |
More data for this Ligand-Target Pair | |