Compile Data Set for Download or QSAR

Found 5953 hits of ic50 for UniProtKB: O43614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559715 (WO2022109117, Example 60) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3cccc(OCCOC(=O)N12)n3 |wD:1.0,3.3,9.31,(-.5,-5.39,;-.13,-3.92,;-1.1,-2.75,;-.29,-1.46,;-.85,-.05,;-2.36,.17,;-3.86,.38,;-2.58,-1.34,;-2.14,1.67,;1.18,-1.84,;1.67,-.33,;2.7,.9,;4.32,1.22,;5.65,2.06,;7.08,1.48,;7.28,-.08,;5.99,-.92,;4.62,-.28,;8.39,-1.27,;9.96,-1.36,;10.67,-2.71,;9.94,-4.03,;8.38,-3.99,;7.51,-5.26,;6.21,-6.09,;4.67,-6.26,;3.19,-5.8,;1.99,-4.79,;.79,-5.72,;1.28,-3.35,;7.66,-2.63,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50601261 (CHEMBL5196538) Show SMILES CC1CC(NS(C)(=O)=O)C2COC3CCC(CC3)c3cccc(OCCOC(=O)N12)n3 |(3.17,5.31,;1.84,4.54,;.47,5.16,;-.6,4,;-2.14,4,;-2.91,5.34,;-2.14,6.67,;-4.24,6.11,;-4.24,4.57,;.17,2.67,;-.6,1.34,;-2.14,1.34,;-2.91,0,;-1.37,0,;-.6,-1.33,;-1.37,-2.66,;-2.91,-2.66,;-3.68,-1.33,;-.6,-4,;-1.37,-5.34,;-.6,-6.67,;.94,-6.67,;1.71,-5.33,;3.06,-3.88,;2.42,-2.1,;3.45,-.66,;2.36,.43,;2.76,1.91,;4.24,2.31,;1.67,3,;.94,-4,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00341 BindingDB Entry DOI: 10.7270/Q2RN3CXS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559716 (WO2022109117, Example 61) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3cccc(OCCCOC(=O)N12)n3 |wD:1.0,3.3,9.32,(16.42,6.26,;15.92,4.82,;16.78,3.57,;15.86,2.36,;16.29,.91,;17.77,.55,;19.25,.2,;18.13,2.03,;17.42,-.93,;14.42,2.87,;13.82,1.42,;12.67,.34,;11.12,.05,;10.85,1.56,;9.44,2.11,;8.17,1.22,;8.46,-.33,;9.89,-.9,;6.96,2.31,;5.4,2.22,;4.49,3.45,;5.13,4.84,;6.67,5.04,;7.38,6.45,;8.52,7.48,;9.99,7.92,;11.53,7.79,;12.91,7.09,;13.94,5.91,;15.26,6.68,;14.46,4.39,;7.52,3.76,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50601262 (CHEMBL5194793) Show SMILES CC1CC(NS(C)(=O)=O)C2COC3CCC(CC3)c3cccc(OCCCOC(=O)N12)n3 |(3.17,5.31,;1.84,4.54,;.47,5.16,;-.6,4,;-2.14,4,;-2.91,5.34,;-2.14,6.67,;-4.24,6.11,;-4.24,4.57,;.17,2.67,;-.6,1.34,;-2.14,1.34,;-2.91,0,;-1.37,0,;-.6,-1.33,;-1.37,-2.66,;-2.91,-2.66,;-3.68,-1.33,;-.6,-4,;-1.37,-5.34,;-.6,-6.67,;.94,-6.67,;1.71,-5.33,;3.45,-5.02,;4.14,-3.24,;3.05,-2.15,;3.45,-.66,;2.36,.43,;2.76,1.91,;4.24,2.31,;1.67,3,;.94,-4,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00341 BindingDB Entry DOI: 10.7270/Q2RN3CXS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50601264 (CHEMBL5177846) Show SMILES CC1CC(NS(C)(=O)=O)C2COC3CCC(CC3)c3nc(OCCOC(=O)N12)c(F)cc3F |(3.17,5.98,;1.84,5.21,;.47,5.82,;-.6,4.67,;-2.14,4.67,;-2.91,6,;-2.14,7.34,;-4.24,6.78,;-4.24,5.24,;.17,3.34,;-.6,2,;-2.14,2,;-2.91,.67,;-1.37,.67,;-.6,-.66,;-1.37,-2,;-2.91,-2,;-3.68,-.66,;-.6,-3.33,;.94,-3.33,;1.71,-4.66,;3.06,-3.21,;2.42,-1.43,;3.45,0,;2.36,1.09,;2.76,2.58,;4.24,2.98,;1.67,3.67,;.94,-6,;1.71,-7.34,;-.6,-6,;-1.37,-4.67,;-2.91,-4.67,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00341 BindingDB Entry DOI: 10.7270/Q2RN3CXS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559737 (WO2022109117, Example 82) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3nc(OCCOC(=O)N12)c(F)cc3F |wD:1.0,3.3,9.29,(-.98,-5.13,;-.61,-3.66,;-1.58,-2.49,;-.77,-1.2,;-1.33,.21,;-2.84,.42,;-4.34,.64,;-3.05,-1.08,;-2.62,1.93,;.7,-1.58,;1.19,-.08,;2.22,1.16,;3.84,1.48,;5.17,2.32,;6.6,1.74,;6.8,.18,;5.51,-.66,;4.14,-.02,;7.91,-1.01,;7.18,-2.37,;7.9,-3.73,;7.03,-5,;5.73,-5.83,;4.19,-6,;2.71,-5.54,;1.51,-4.53,;.31,-5.46,;.8,-3.09,;9.46,-3.77,;10.21,-5.09,;10.19,-2.45,;9.48,-1.1,;10.3,.18,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559656 (WO2022109117, Example 1) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3ccccc3\C=C/OC(=O)N12 |wU:1.0,3.3,14.19,17.17,11.34,c:28,(7.84,-2.1,;6.55,-1.27,;6.46,.27,;4.97,.66,;4.41,2.09,;5.37,3.29,;6.57,2.33,;4.17,4.26,;6.33,4.5,;5.77,5.93,;7.86,4.26,;4.14,-.64,;2.72,.03,;1.13,.06,;-.2,-.85,;.94,-1.91,;.69,-3.42,;-.71,-4.05,;-1.86,-2.99,;-1.66,-1.45,;-.07,-5.54,;-1.54,-6.01,;-1.86,-7.52,;-.72,-8.55,;.75,-8.08,;1.07,-6.57,;2.72,-6.8,;4.2,-6.14,;5.18,-4.87,;5.49,-3.35,;7.03,-3.32,;5.11,-1.83,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50601259 (CHEMBL5195414) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2COC3CCC(CC3)c3ccccc3\C=C\OC(=O)N12 |r,wU:11.11,3.3,1.0,t:28,(3.17,4.64,;1.84,3.87,;.47,4.49,;-.6,3.34,;-2.14,3.34,;-2.91,4.67,;-4.24,5.44,;-4.24,3.9,;-2.14,6,;-2.91,7.34,;-.6,6,;.17,2,;-.6,.67,;-2.14,.67,;-2.91,-.66,;-1.37,-.66,;-.6,-2,;-1.37,-3.33,;-2.91,-3.33,;-3.68,-2,;-.6,-4.67,;-1.37,-6.01,;-.6,-7.34,;.94,-7.34,;1.71,-6,;.94,-4.67,;1.71,-3.33,;1.19,-1.76,;2.41,-.63,;2.76,1.25,;4.24,1.65,;1.67,2.34,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00341 BindingDB Entry DOI: 10.7270/Q2RN3CXS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559734 (WO2022109117, Example 79) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3nc(OCCOC(=O)N12)ccc3C |wD:1.0,3.3,9.29,(-.94,-5.15,;-.57,-3.68,;-1.54,-2.51,;-.73,-1.23,;-1.29,.18,;-2.8,.4,;-4.3,.62,;-3.01,-1.1,;-2.58,1.9,;.74,-1.6,;1.23,-.1,;2.27,1.13,;3.88,1.46,;5.21,2.29,;6.64,1.71,;6.85,.16,;5.55,-.68,;4.18,-.05,;7.96,-1.03,;7.22,-2.39,;7.94,-3.75,;7.07,-5.02,;5.77,-5.85,;4.23,-6.02,;2.75,-5.57,;1.55,-4.55,;.36,-5.49,;.84,-3.12,;9.5,-3.8,;10.24,-2.47,;9.52,-1.13,;10.34,.15,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50601260 (CHEMBL5190821) Show SMILES CC1CC(NS(=O)(=O)N(C)C)C2COC3CCC(CC3)c3cccc(OCCOC(=O)N12)c3 |(3.17,4.64,;1.84,3.87,;.47,4.49,;-.6,3.34,;-2.14,3.34,;-2.91,4.67,;-4.24,5.44,;-4.24,3.9,;-2.14,6,;-2.91,7.34,;-.6,6,;.17,2,;-.6,.67,;-2.14,.67,;-2.91,-.66,;-1.37,-.66,;-.6,-2,;-1.37,-3.33,;-2.91,-3.33,;-3.68,-2,;-.6,-4.67,;-1.37,-6.01,;-.6,-7.34,;.94,-7.34,;1.71,-6,;3.06,-4.54,;2.42,-2.77,;3.45,-1.33,;2.36,-.24,;2.76,1.25,;4.24,1.65,;1.67,2.34,;.94,-4.67,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00341 BindingDB Entry DOI: 10.7270/Q2RN3CXS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559675 (WO2022109117, Example 20) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCCC(=O)N12)c3 |wU:14.14,17.16,wD:1.0,3.3,11.33,(16.31,5.89,;15.93,4.42,;16.91,3.25,;16.1,1.97,;16.66,.56,;18.16,.34,;18.38,1.84,;17.95,-1.16,;19.67,.12,;20.23,-1.29,;20.61,1.32,;14.63,2.34,;14.14,.84,;13.1,-.39,;11.49,-.71,;10.16,-1.55,;8.74,-.97,;8.53,.58,;9.82,1.42,;11.19,.79,;7.42,1.77,;5.85,1.87,;5.14,3.21,;5.88,4.53,;7.43,4.49,;8.3,5.76,;9.6,6.59,;11.14,6.76,;12.62,6.31,;13.82,5.29,;15.01,6.23,;14.53,3.86,;8.15,3.13,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559670 (WO2022109117, Example 15 | WO2022109117, Example 1...) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCOC(=O)N12)c3 |wU:14.14,17.16,wD:1.0,3.3,11.33,(16.49,5.93,;16.12,4.46,;17.09,3.29,;16.28,2.01,;16.85,.6,;18.35,.38,;18.57,1.88,;18.13,-1.12,;19.85,.16,;20.41,-1.25,;20.79,1.36,;14.81,2.38,;14.33,.88,;13.29,-.35,;11.68,-.68,;10.35,-1.51,;8.92,-.93,;8.71,.62,;10,1.46,;11.38,.83,;7.6,1.81,;6.04,1.9,;5.32,3.25,;6.06,4.57,;7.61,4.53,;8.49,5.8,;9.79,6.63,;11.33,6.8,;12.81,6.34,;14,5.33,;15.2,6.26,;14.71,3.89,;8.34,3.17,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50601263 (CHEMBL5206338) Show SMILES CC1CC(NS(C)(=O)=O)C2COC3CCC(CC3)c3nc(OCCOC(=O)N12)ccc3C |(3.17,5.31,;1.84,4.54,;.47,5.16,;-.6,4,;-2.14,4,;-2.91,5.34,;-2.14,6.67,;-4.24,6.11,;-4.24,4.57,;.17,2.67,;-.6,1.34,;-2.14,1.34,;-2.91,0,;-1.37,0,;-.6,-1.33,;-1.37,-2.66,;-2.91,-2.66,;-3.68,-1.33,;-.6,-4,;.94,-4,;1.71,-5.33,;3.06,-3.88,;2.42,-2.1,;3.45,-.66,;2.36,.43,;2.76,1.91,;4.24,2.31,;1.67,3,;.94,-6.67,;-.6,-6.67,;-1.37,-5.34,;-2.91,-5.34,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00341 BindingDB Entry DOI: 10.7270/Q2RN3CXS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559657 (WO2022109117, Example 2) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2CO[C@H]3CC[C@H](CC3)c3ccccc3\C=C/OC(=O)N12 |wU:1.0,3.3,12.17,15.15,9.32,c:26,(7.84,-2.1,;6.55,-1.27,;6.46,.27,;4.97,.66,;4.41,2.09,;5.37,3.29,;6.33,4.5,;6.57,2.33,;4.17,4.26,;4.14,-.64,;2.72,.03,;1.13,.06,;-.2,-.85,;.94,-1.91,;.69,-3.42,;-.71,-4.05,;-1.86,-2.99,;-1.66,-1.45,;-.07,-5.54,;-1.54,-6.01,;-1.86,-7.52,;-.72,-8.55,;.75,-8.08,;1.07,-6.57,;2.72,-6.8,;4.2,-6.14,;5.18,-4.87,;5.49,-3.35,;7.03,-3.32,;5.11,-1.83,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559711 (WO2022109117, Example 56) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3ccc(F)c(OCCOC(=O)N12)n3 |wD:1.0,3.3,9.32,(-.41,-5.44,;-.04,-3.96,;-1.01,-2.8,;-.2,-1.51,;-.76,-.1,;-2.27,.12,;-3.77,.33,;-2.49,-1.39,;-2.05,1.62,;1.27,-1.88,;1.76,-.38,;2.79,.85,;4.41,1.17,;5.74,2.01,;7.17,1.43,;7.37,-.13,;6.08,-.96,;4.71,-.33,;8.48,-1.32,;10.05,-1.41,;10.76,-2.76,;10.03,-4.08,;10.78,-5.4,;8.47,-4.04,;7.6,-5.31,;6.3,-6.14,;4.76,-6.31,;3.28,-5.85,;2.08,-4.84,;.88,-5.77,;1.37,-3.4,;7.75,-2.68,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559745 (WO2022109117, Example 90) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3cccc(NCCCOC(=O)N12)n3 |wD:3.3,9.32,1.0,(14.55,5.67,;14.04,4.23,;14.91,2.98,;13.98,1.77,;14.42,.31,;15.9,-.04,;17.38,-.39,;16.25,1.44,;15.55,-1.52,;12.55,2.28,;11.94,.82,;10.79,-.25,;9.24,-.54,;8.97,.97,;7.56,1.52,;6.29,.62,;6.58,-.92,;8.01,-1.5,;5.08,1.72,;3.52,1.63,;2.61,2.86,;3.25,4.25,;4.79,4.45,;5.49,5.86,;6.64,6.89,;8.11,7.33,;9.65,7.2,;11.03,6.5,;12.06,5.32,;13.38,6.09,;12.58,3.8,;5.64,3.17,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559747 (WO2022109117, Example 92) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3ccc(F)c(NCCOC(=O)N12)n3 |wD:1.0,3.3,9.32,(16.35,5.9,;15.98,4.43,;16.95,3.26,;16.14,1.97,;16.7,.56,;18.21,.35,;19.71,.13,;18.42,1.85,;17.99,-1.16,;14.66,2.35,;14.18,.85,;13.14,-.39,;11.53,-.71,;10.2,-1.55,;8.77,-.97,;8.56,.59,;9.86,1.43,;11.23,.79,;7.45,1.78,;5.89,1.87,;5.17,3.22,;5.91,4.54,;5.16,5.86,;7.46,4.5,;8.34,5.77,;9.64,6.6,;11.18,6.77,;12.66,6.31,;13.86,5.3,;15.05,6.23,;14.56,3.86,;8.19,3.14,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559712 (WO2022109117, Example 57) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3ccc(F)c(OCCCOC(=O)N12)n3 |wD:1.0,3.3,9.33,(16.71,6.34,;16.2,4.9,;17.07,3.65,;16.14,2.44,;16.58,.98,;18.06,.63,;19.54,.28,;18.41,2.11,;17.7,-.85,;14.71,2.95,;14.1,1.49,;12.95,.41,;11.4,.12,;11.13,1.64,;9.71,2.19,;8.45,1.29,;8.74,-.25,;10.17,-.83,;7.24,2.39,;5.68,2.3,;4.77,3.53,;5.41,4.92,;4.51,6.15,;6.95,5.12,;7.65,6.53,;8.8,7.56,;10.27,8.01,;11.81,7.87,;13.19,7.17,;14.22,5.99,;15.54,6.76,;14.74,4.47,;7.8,3.84,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559658 (WO2022109117, Example 3) Show SMILES COC[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(F)c3\C=C/OC(=O)N12 |wU:5.5,14.19,17.17,11.35,3.2,c:29,(9.41,.06,;9.25,-1.48,;7.84,-2.1,;6.55,-1.27,;6.46,.27,;4.97,.66,;4.41,2.09,;5.37,3.29,;6.33,4.5,;6.57,2.33,;4.17,4.26,;4.14,-.64,;2.72,.03,;1.13,.06,;-.2,-.85,;.94,-1.91,;.69,-3.42,;-.71,-4.05,;-1.86,-2.99,;-1.66,-1.45,;-.07,-5.54,;-1.54,-6.01,;-1.86,-7.52,;-.72,-8.55,;.75,-8.08,;1.89,-9.11,;1.07,-6.57,;2.72,-6.8,;4.2,-6.14,;5.18,-4.87,;5.49,-3.35,;7.03,-3.32,;5.11,-1.83,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559673 (WO2022109117, Example 18) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCCOC(=O)N12)c3 |wD:3.3,14.14,17.16,11.34,1.0,(17.24,6.51,;16.73,5.07,;17.59,3.82,;16.67,2.61,;17.1,1.15,;18.58,.8,;18.94,2.28,;18.23,-.68,;20.06,.45,;20.5,-1.01,;21.11,1.55,;15.23,3.12,;14.63,1.66,;13.48,.58,;11.93,.3,;11.66,1.81,;10.25,2.36,;8.98,1.46,;9.27,-.08,;10.7,-.66,;7.77,2.55,;6.21,2.47,;5.3,3.7,;5.95,5.09,;7.48,5.29,;8.19,6.69,;9.33,7.73,;10.8,8.17,;12.34,8.03,;13.72,7.33,;14.75,6.16,;16.07,6.92,;15.27,4.64,;8.33,4.01,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559725 (WO2022109117, Example 70) Show SMILES COc1cc2OCCOC(=O)N3[C@H](C)C[C@H](NS(C)(=O)=O)[C@@H]3COC3CCC(CC3)c(c1)n2 |wD:12.12,15.15,21.21,(12.69,-3.91,;11.95,-2.59,;10.43,-2.57,;9.69,-3.9,;8.14,-3.85,;7.26,-5.13,;5.96,-5.96,;4.42,-6.12,;2.94,-5.67,;1.74,-4.66,;.55,-5.59,;1.04,-3.22,;-.38,-3.78,;-.75,-5.26,;-1.35,-2.62,;-.54,-1.33,;-1.1,.08,;-2.6,.3,;-4.11,.52,;-2.82,-1.21,;-2.39,1.8,;.94,-1.7,;1.42,-.2,;2.46,1.03,;4.07,1.36,;5.4,2.19,;6.83,1.61,;7.04,.05,;5.75,-.78,;4.37,-.15,;8.15,-1.14,;9.71,-1.23,;7.41,-2.49,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559760 (WO2022109117, Example 105) Show SMILES COc1cc2OCCOC(=O)N3[C@H](C)C[C@H](NS(=O)(=O)C(F)F)[C@@H]3COC3CCC(CC3)c(c1)n2 |wD:12.12,15.15,23.23,(2.45,1.83,;3.22,3.13,;4.74,3.12,;5.48,4.44,;7.03,4.4,;7.91,5.67,;9.21,6.5,;10.75,6.67,;12.23,6.21,;13.43,5.2,;14.62,6.13,;14.14,3.76,;15.55,4.33,;15.92,5.8,;16.52,3.16,;15.71,1.87,;16.27,.46,;17.78,.25,;17.99,1.75,;17.56,-1.26,;19.28,.03,;19.84,-1.38,;20.22,1.22,;14.24,2.25,;13.75,.75,;12.71,-.49,;11.1,-.81,;9.77,-1.65,;8.34,-1.07,;8.13,.49,;9.43,1.33,;10.8,.69,;7.02,1.68,;5.46,1.77,;7.76,3.04,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559759 (WO2022109117, Example 104) Show SMILES COc1cc2OCCOC(=O)N3[C@H](C)C[C@H](NS(=O)(=O)CF)[C@@H]3COC3CCC(CC3)c(c1)n2 |wD:12.12,15.15,22.22,(2.45,1.83,;3.22,3.13,;4.74,3.12,;5.48,4.44,;7.03,4.4,;7.91,5.67,;9.21,6.5,;10.75,6.67,;12.23,6.21,;13.43,5.2,;14.62,6.13,;14.14,3.76,;15.55,4.33,;15.92,5.8,;16.52,3.16,;15.71,1.87,;16.27,.46,;17.78,.25,;17.99,1.75,;17.56,-1.26,;19.28,.03,;19.84,-1.38,;14.24,2.25,;13.75,.75,;12.71,-.49,;11.1,-.81,;9.77,-1.65,;8.34,-1.07,;8.13,.49,;9.43,1.33,;10.8,.69,;7.02,1.68,;5.46,1.77,;7.76,3.04,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559736 (WO2022109117, Example 81) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3nc(OCCCOC(=O)N12)c(F)cc3F |wD:1.0,3.3,9.30,(15.06,5.83,;14.55,4.4,;15.41,3.14,;14.49,1.93,;14.93,.47,;16.41,.12,;17.89,-.23,;16.76,1.6,;16.06,-1.36,;13.05,2.44,;12.45,.98,;11.3,-.09,;9.74,-.38,;9.48,1.13,;8.06,1.68,;6.79,.78,;7.08,-.76,;8.51,-1.34,;5.58,1.88,;6.14,3.33,;5.29,4.62,;5.99,6.02,;7.14,7.06,;8.62,7.5,;10.16,7.36,;11.54,6.66,;12.57,5.49,;13.89,6.25,;13.09,3.96,;3.75,4.41,;2.85,5.64,;3.11,3.02,;4.02,1.79,;3.37,.41,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559697 (WO2022109117, Example 42) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cc(F)cc(OCCCOC(=O)N12)c3 |wU:1.0,3.3,12.12,15.14,9.33,(18.09,4.06,;16.93,5.05,;17.05,6.57,;15.65,7.15,;15.3,8.63,;16.4,9.68,;17.51,10.72,;17.45,8.57,;15.36,10.78,;14.66,6,;13.41,6.95,;11.87,7.31,;10.39,6.79,;10.91,5.34,;9.96,4.16,;8.42,4.3,;7.9,5.78,;8.84,7,;7.92,2.75,;6.52,2.04,;6.35,.52,;4.96,-.1,;7.6,-.36,;9.03,.24,;10.34,-.63,;11.85,-.95,;13.35,-.6,;14.61,.29,;15.46,1.59,;15.76,3.12,;17.29,3.12,;15.45,4.7,;9.13,1.78,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559669 (WO2022109117, Example 14) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCCC(=O)N12)c3 |wU:14.14,17.16,wD:1.0,3.3,11.33,(16.68,5.97,;16.31,4.49,;17.28,3.33,;16.47,2.04,;17.03,.63,;18.54,.42,;18.75,1.92,;18.32,-1.09,;20.04,.2,;20.6,-1.21,;20.98,1.39,;15,2.42,;14.51,.92,;13.48,-.31,;11.86,-.64,;10.53,-1.48,;9.11,-.9,;8.9,.66,;10.19,1.5,;11.57,.86,;7.79,1.85,;6.23,1.94,;5.51,3.29,;6.25,4.61,;7.8,4.57,;8.68,5.84,;9.98,6.67,;11.51,6.83,;12.99,6.38,;14.19,5.37,;15.38,6.3,;14.9,3.93,;8.53,3.21,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559670 (WO2022109117, Example 15 | WO2022109117, Example 1...) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCOC(=O)N12)c3 |wU:14.14,17.16,wD:1.0,3.3,11.33,(16.49,5.93,;16.12,4.46,;17.09,3.29,;16.28,2.01,;16.85,.6,;18.35,.38,;18.57,1.88,;18.13,-1.12,;19.85,.16,;20.41,-1.25,;20.79,1.36,;14.81,2.38,;14.33,.88,;13.29,-.35,;11.68,-.68,;10.35,-1.51,;8.92,-.93,;8.71,.62,;10,1.46,;11.38,.83,;7.6,1.81,;6.04,1.9,;5.32,3.25,;6.06,4.57,;7.61,4.53,;8.49,5.8,;9.79,6.63,;11.33,6.8,;12.81,6.34,;14,5.33,;15.2,6.26,;14.71,3.89,;8.34,3.17,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559668 (WO2022109117, Example 13) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCCOC(=O)N12)c3 |wD:1.0,3.3,14.14,17.16,11.34,(17.2,6.5,;16.7,5.06,;17.56,3.81,;16.64,2.6,;17.07,1.14,;18.55,.79,;18.91,2.27,;18.2,-.69,;20.03,.44,;20.47,-1.02,;21.08,1.55,;15.2,3.11,;14.6,1.65,;13.45,.58,;11.9,.29,;11.63,1.8,;10.21,2.35,;8.95,1.45,;9.24,-.09,;10.66,-.66,;7.74,2.55,;6.18,2.46,;5.27,3.69,;5.91,5.08,;7.45,5.28,;8.15,6.68,;9.3,7.72,;10.77,8.16,;12.31,8.02,;13.69,7.32,;14.72,6.15,;16.04,6.91,;15.24,4.63,;8.3,4,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559726 (WO2022109117, Example 71) Show SMILES COc1cc2OCCCOC(=O)N3[C@H](C)C[C@H](NS(C)(=O)=O)[C@@H]3COC3CCC(CC3)c(c1)n2 |wD:13.13,16.16,22.22,(1.33,4.31,;2.22,3.08,;3.74,3.23,;4.38,4.62,;5.92,4.82,;6.63,6.23,;7.78,7.26,;9.25,7.71,;10.79,7.57,;12.17,6.87,;13.2,5.7,;14.52,6.46,;13.72,4.17,;15.18,4.61,;15.69,6.04,;16.05,3.35,;15.12,2.14,;15.56,.68,;17.04,.33,;18.52,-.02,;17.39,1.81,;16.69,-1.15,;13.69,2.65,;13.08,1.19,;11.93,.11,;10.38,-.18,;10.11,1.34,;8.69,1.89,;7.43,.99,;7.71,-.55,;9.14,-1.13,;6.21,2.08,;4.65,2,;6.78,3.54,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559758 (WO2022109117, Example 103) Show SMILES CCS(=O)(=O)N[C@H]1C[C@@H](C)N2[C@H]1COC1CCC(CC1)c1cc(OC)cc(OCCOC2=O)n1 |wD:8.8,6.5,11.10,(20.04,-1.37,;19.47,.05,;17.96,.27,;18.18,1.78,;17.74,-1.24,;16.45,.49,;15.88,1.9,;16.7,3.2,;15.72,4.37,;16.09,5.85,;14.3,3.8,;14.4,2.28,;13.91,.77,;12.87,-.47,;11.25,-.79,;9.91,-1.64,;8.48,-1.05,;8.27,.51,;9.57,1.35,;10.95,.72,;7.15,1.71,;5.58,1.8,;4.86,3.16,;3.33,3.17,;2.56,1.86,;5.6,4.48,;7.16,4.44,;8.04,5.72,;9.35,6.55,;10.9,6.72,;12.39,6.27,;13.59,5.25,;14.79,6.19,;7.89,3.07,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559722 (WO2022109117, Example 67) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3cc(C)cc(OCCCOC(=O)N12)n3 |wD:1.0,3.3,9.33,(15.92,6.11,;15.41,4.68,;16.28,3.42,;15.35,2.21,;15.79,.75,;17.27,.4,;18.75,.05,;17.62,1.88,;16.92,-1.08,;13.92,2.72,;13.31,1.26,;12.16,.18,;10.61,-.11,;10.34,1.41,;8.92,1.96,;7.66,1.06,;7.94,-.48,;9.37,-1.06,;6.44,2.16,;4.88,2.07,;3.97,3.3,;2.45,3.15,;4.61,4.69,;6.15,4.9,;6.86,6.3,;8.01,7.34,;9.48,7.78,;11.02,7.64,;12.4,6.94,;13.43,5.77,;14.75,6.53,;13.95,4.24,;7.01,3.61,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559677 (WO2022109117, Example 22) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(CCCCCC(=O)N12)c3 |wD:3.3,14.14,17.16,11.34,1.0,(16.59,6.33,;16.09,4.9,;16.95,3.65,;16.03,2.44,;16.46,.99,;17.93,.64,;18.28,2.11,;17.58,-.83,;19.41,.29,;19.84,-1.16,;20.45,1.39,;14.6,2.95,;13.99,1.5,;12.85,.42,;11.3,.14,;11.04,1.65,;9.62,2.19,;8.37,1.3,;8.65,-.24,;10.07,-.81,;7.16,2.39,;5.61,2.3,;4.7,3.53,;5.34,4.91,;6.87,5.11,;7.57,6.51,;8.71,7.54,;10.18,7.98,;11.71,7.85,;13.09,7.15,;14.12,5.98,;15.43,6.74,;14.63,4.46,;7.72,3.83,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559735 (WO2022109117, Example 80) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3ccc(C)c(OCCCOC(=O)N12)n3 |wD:1.0,3.3,9.33,(15.17,5.87,;14.66,4.43,;15.53,3.18,;14.6,1.97,;15.04,.51,;16.52,.16,;18,-.2,;16.87,1.64,;16.17,-1.33,;13.17,2.47,;12.56,1.02,;11.41,-.06,;9.86,-.35,;9.59,1.17,;8.17,1.71,;6.91,.82,;7.19,-.73,;8.62,-1.3,;5.69,1.91,;4.13,1.83,;3.22,3.06,;3.86,4.45,;2.96,5.68,;5.4,4.65,;6.11,6.05,;7.26,7.09,;8.73,7.54,;10.27,7.4,;11.65,6.7,;12.68,5.52,;14,6.29,;13.2,4,;6.26,3.36,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM514632 (US11098029, Example 67) Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1 |r,wU:8.8,5.5,16.17,19.19,22.26,(8.37,-3.54,;7.03,-4.31,;5.7,-3.54,;4.36,-4.31,;5.7,-2,;6.94,-1.1,;8.41,-1.57,;6.47,.37,;4.93,.37,;4.02,1.61,;4.65,3.02,;3.24,3.65,;5.28,4.43,;6.06,2.39,;7.2,3.42,;6.83,1.06,;4.45,-1.1,;2.99,-1.57,;1.84,-.54,;.38,-1.02,;.06,-2.52,;-1.41,-3,;-2.55,-1.97,;-2.23,-.46,;-.77,.01,;-4.02,-2.45,;-4.34,-3.95,;-5.8,-4.43,;-6.94,-3.4,;-6.62,-1.89,;-7.77,-.86,;-5.16,-1.41,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as increase in intracellular Ca2+ mobilization by measuring IP3 producti...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00501 BindingDB Entry DOI: 10.7270/Q2SQ944V
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM514601 (US11098029, Example 37) Show SMILES COc1ccc(CN([C@H]2C[C@@H](C)N([C@H]2CO[C@H]2CC[C@H](CC2)c2cccc(F)c2)C(=O)OCc2ccccc2)S(=O)(=O)N(C)C)cc1 |r,wU:10.10,8.7,13.14,16.16,19.23,(-8.92,-1.04,;-7.39,-1.2,;-6.49,.05,;-7.11,1.45,;-6.21,2.7,;-4.67,2.54,;-3.77,3.78,;-2.24,3.62,;-1.33,4.87,;-1.81,6.33,;-.56,7.24,;-.56,8.78,;.68,6.33,;.21,4.87,;1.11,3.62,;2.64,3.78,;3.55,2.54,;5.08,2.7,;5.99,1.45,;5.36,.05,;3.83,-.12,;2.92,1.13,;6.26,-1.2,;5.64,-2.61,;6.54,-3.85,;8.08,-3.69,;8.7,-2.29,;10.23,-2.12,;7.8,-1.04,;2.15,6.81,;3.29,5.78,;2.47,8.31,;1.32,9.35,;1.64,10.85,;.5,11.88,;.82,13.39,;2.28,13.86,;3.43,12.83,;3.11,11.33,;-1.61,2.22,;-.2,2.84,;-3.02,1.59,;-.99,.81,;.55,.65,;-1.89,-.44,;-4.05,1.13,;-4.95,-.12,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C250MP
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50561747 (CHEMBL4740509) Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)NCF)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1 |r,wU:22.26,19.19,16.17,8.8,5.5,(39.66,-14.61,;39.34,-13.1,;40.49,-12.08,;41.95,-12.55,;40.17,-10.57,;41.2,-9.43,;42.74,-9.59,;40.44,-8.09,;38.93,-8.41,;37.79,-7.37,;38.11,-5.86,;39.2,-4.77,;39.6,-6.26,;36.97,-4.84,;37.29,-3.33,;38.76,-2.86,;38.77,-9.94,;37.43,-10.71,;36.1,-9.94,;34.76,-10.7,;34.76,-12.24,;33.44,-13,;32.11,-12.24,;32.11,-10.7,;33.44,-9.92,;30.78,-13.01,;30.78,-14.55,;29.45,-15.32,;28.11,-14.56,;28.11,-13.01,;26.77,-12.25,;29.44,-12.24,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as increase in intracellular Ca2+ mobilization by measuring IP3 producti...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00501 BindingDB Entry DOI: 10.7270/Q2SQ944V
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM514590 (US11098029, Example 26) Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)CF)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1 |r,wU:15.16,8.8,5.5,wD:21.25,18.18,(3.21,-6.71,;4.12,-5.46,;3.49,-4.05,;1.96,-3.89,;4.4,-2.81,;5.94,-2.81,;6.84,-4.05,;6.41,-1.34,;5.17,-.44,;5.17,1.1,;6.5,1.87,;7.27,.54,;5.73,3.21,;7.83,2.64,;7.83,4.18,;3.92,-1.34,;2.45,-.87,;1.31,-1.9,;-.15,-1.42,;-.47,.08,;-1.94,.56,;-3.08,-.47,;-2.76,-1.98,;-1.3,-2.45,;-4.55,.01,;-4.87,1.51,;-6.33,1.99,;-7.48,.96,;-7.16,-.55,;-8.3,-1.58,;-5.69,-1.03,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C250MP
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559729 (WO2022109117, Example 74) Show SMILES COc1cc2nc(OCCOC(=O)N3[C@H](C)C[C@H](NS(C)(=O)=O)[C@@H]3COC3CCC2CC3)c1F |wD:14.14,17.17,23.23,(12.59,-3.85,;11.84,-2.53,;10.32,-2.51,;9.61,-1.17,;8.05,-1.08,;7.31,-2.43,;8.04,-3.79,;7.16,-5.06,;5.86,-5.89,;4.32,-6.06,;2.84,-5.61,;1.65,-4.59,;.45,-5.53,;.94,-3.16,;-.47,-3.72,;-.84,-5.19,;-1.44,-2.56,;-.63,-1.27,;-1.2,.14,;-2.7,.36,;-4.2,.57,;-2.92,-1.15,;-2.48,1.86,;.84,-1.64,;1.32,-.14,;2.36,1.09,;3.97,1.41,;5.3,2.25,;6.73,1.67,;6.94,.11,;5.64,-.73,;4.27,-.09,;9.59,-3.84,;10.34,-5.16,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559702 (WO2022109117, Example 47) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3cccc(OCCCOC(=O)N12)c3F |wD:1.0,3.3,9.32,(17.42,6.56,;16.91,5.12,;17.78,3.87,;16.85,2.66,;17.29,1.2,;18.77,.85,;20.25,.5,;19.12,2.33,;18.41,-.63,;15.42,3.17,;14.81,1.71,;13.66,.63,;12.11,.34,;11.84,1.86,;10.43,2.41,;9.17,1.51,;9.45,-.03,;10.88,-.61,;7.95,2.6,;6.39,2.52,;5.48,3.75,;6.13,5.14,;7.66,5.34,;8.37,6.74,;9.51,7.78,;10.98,8.22,;12.52,8.08,;13.9,7.38,;14.93,6.21,;16.25,6.97,;15.45,4.69,;8.51,4.06,;10.03,4.22,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559721 (WO2022109117, Example 66) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3cc(C)cc(OCCOC(=O)N12)n3 |wD:1.0,3.3,9.32,(-.66,-5.3,;-.28,-3.83,;-1.26,-2.66,;-.45,-1.37,;-1.01,.04,;-2.51,.25,;-4.02,.47,;-2.73,-1.25,;-2.3,1.76,;1.03,-1.75,;1.51,-.25,;2.55,.98,;4.16,1.31,;5.49,2.15,;6.92,1.57,;7.13,.01,;5.84,-.83,;4.46,-.19,;8.24,-1.18,;9.8,-1.27,;10.52,-2.62,;12.04,-2.64,;9.78,-3.94,;8.23,-3.9,;7.35,-5.17,;6.05,-6,;4.51,-6.17,;3.03,-5.71,;1.84,-4.7,;.64,-5.63,;1.13,-3.26,;7.5,-2.54,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.270	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM514589 (US11098029, Example 25) Show SMILES CNS(=O)(=O)N[C@H]1C[C@@H](C)N([C@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1)C(=O)OC |r,wU:17.21,14.14,11.12,6.5,8.8,(-.26,2.51,;.65,1.26,;2.18,1.42,;2.02,2.96,;2.34,-.11,;3.71,1.59,;4.62,.34,;6.16,.34,;6.63,-1.13,;7.96,-1.9,;5.39,-2.03,;4.14,-1.13,;2.65,-1.52,;1.56,-.43,;.08,-.83,;-.32,-2.32,;-1.81,-2.72,;-2.9,-1.63,;-2.5,-.14,;-1.01,.26,;-4.39,-2.03,;-4.79,-3.52,;-6.27,-3.92,;-7.36,-2.83,;-6.96,-1.34,;-8.05,-.25,;-5.48,-.94,;5.39,-3.57,;4.05,-4.34,;6.72,-4.34,;8.05,-3.57,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.270	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as increase in intracellular Ca2+ mobilization by measuring IP3 producti...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00501 BindingDB Entry DOI: 10.7270/Q2SQ944V
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM514589 (US11098029, Example 25) Show SMILES CNS(=O)(=O)N[C@H]1C[C@@H](C)N([C@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1)C(=O)OC |r,wU:17.21,14.14,11.12,6.5,8.8,(-.26,2.51,;.65,1.26,;2.18,1.42,;2.02,2.96,;2.34,-.11,;3.71,1.59,;4.62,.34,;6.16,.34,;6.63,-1.13,;7.96,-1.9,;5.39,-2.03,;4.14,-1.13,;2.65,-1.52,;1.56,-.43,;.08,-.83,;-.32,-2.32,;-1.81,-2.72,;-2.9,-1.63,;-2.5,-.14,;-1.01,.26,;-4.39,-2.03,;-4.79,-3.52,;-6.27,-3.92,;-7.36,-2.83,;-6.96,-1.34,;-8.05,-.25,;-5.48,-.94,;5.39,-3.57,;4.05,-4.34,;6.72,-4.34,;8.05,-3.57,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C250MP
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559699 (WO2022109117, Example 44) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3cc(F)cc(OCCCCC(=O)N12)c3 |wD:1.0,3.3,9.33,(17.39,6.55,;16.89,5.11,;17.75,3.86,;16.83,2.66,;17.26,1.2,;18.74,.85,;20.22,.5,;19.09,2.33,;18.39,-.63,;15.4,3.16,;14.79,1.71,;13.64,.63,;12.09,.34,;11.83,1.86,;10.41,2.4,;9.15,1.51,;9.44,-.03,;10.86,-.61,;7.94,2.6,;6.38,2.52,;5.47,3.74,;3.96,3.59,;6.12,5.13,;7.65,5.33,;8.36,6.73,;9.5,7.77,;10.97,8.21,;12.51,8.07,;13.89,7.37,;14.91,6.2,;16.23,6.96,;15.43,4.68,;8.5,4.05,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559665 (WO2022109117, Example 10) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCCCC(=O)N12)c3 |wD:1.0,3.3,14.14,17.16,11.34,(17.39,6.55,;16.89,5.11,;17.75,3.86,;16.83,2.66,;17.26,1.2,;18.74,.85,;19.09,2.33,;18.39,-.63,;20.22,.5,;20.65,-.96,;21.26,1.6,;15.4,3.16,;14.79,1.71,;13.64,.63,;12.09,.34,;11.83,1.86,;10.41,2.4,;9.15,1.51,;9.44,-.03,;10.86,-.61,;7.94,2.6,;6.38,2.52,;5.47,3.74,;6.12,5.13,;7.65,5.33,;8.36,6.73,;9.5,7.77,;10.97,8.21,;12.51,8.07,;13.89,7.37,;14.91,6.2,;16.23,6.96,;15.43,4.68,;8.5,4.05,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559746 (WO2022109117, Example 91) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3cccc(n3)N(C)CCCOC(=O)N12 |wD:3.3,9.35,1.0,(14.34,5.61,;13.83,4.17,;14.7,2.92,;13.77,1.71,;14.21,.25,;15.69,-.1,;17.17,-.45,;16.04,1.38,;15.34,-1.58,;12.34,2.22,;11.73,.76,;10.58,-.32,;9.03,-.61,;8.76,.91,;7.34,1.46,;6.08,.56,;6.37,-.98,;7.79,-1.56,;4.87,1.65,;3.31,1.57,;2.39,2.8,;3.04,4.19,;4.57,4.39,;5.43,3.11,;5.28,5.8,;4.07,6.72,;6.43,6.83,;7.9,7.27,;9.44,7.14,;10.82,6.44,;11.85,5.26,;13.17,6.03,;12.37,3.74,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559713 (WO2022109117, Example 58) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3nc(OCCOC(=O)N12)ccc3OC(F)(F)F |wD:1.0,3.3,9.29,(-.46,-5.42,;-.09,-3.95,;-1.06,-2.78,;-.25,-1.49,;-.81,-.07,;-2.32,.15,;-3.83,.36,;-2.54,-1.36,;-2.1,1.65,;1.23,-1.86,;1.71,-.36,;2.75,.88,;4.37,1.21,;5.71,2.05,;7.14,1.46,;7.35,-.1,;6.05,-.94,;4.67,-.3,;8.46,-1.29,;7.72,-2.65,;8.45,-4.02,;7.57,-5.29,;6.27,-6.12,;4.72,-6.29,;3.24,-5.84,;2.04,-4.82,;.84,-5.76,;1.33,-3.38,;10.01,-4.06,;10.74,-2.73,;10.03,-1.38,;10.85,-.1,;10.15,1.25,;8.63,1.32,;10.98,2.53,;11.67,1.18,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559674 (WO2022109117, Example 19) Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCCCC(=O)N12)c3 |wD:3.3,14.14,17.16,11.34,1.0,(17.21,6.5,;16.71,5.07,;17.57,3.81,;16.65,2.61,;17.08,1.15,;18.56,.8,;18.91,2.28,;18.21,-.68,;20.04,.45,;20.47,-1.01,;21.08,1.55,;15.21,3.11,;14.61,1.66,;13.46,.58,;11.91,.29,;11.65,1.81,;10.23,2.36,;8.97,1.46,;9.26,-.08,;10.68,-.66,;7.76,2.55,;6.2,2.47,;5.29,3.7,;5.94,5.08,;7.47,5.28,;8.17,6.68,;9.32,7.72,;10.79,8.16,;12.33,8.02,;13.7,7.32,;14.73,6.15,;16.05,6.91,;15.25,4.63,;8.32,4,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559751 (WO2022109117, Example 96) Show SMILES CS(=O)(=O)N[C@H]1C[C@@H](CO)N2[C@H]1COC1CCC(CC1)c1nc(OCCOC2=O)ccc1C(F)(F)F |wD:7.7,5.4,11.10,(19.65,.09,;18.14,.31,;18.36,1.82,;17.92,-1.2,;16.62,.53,;16.06,1.95,;16.87,3.24,;15.89,4.42,;16.27,5.9,;15.17,6.96,;14.48,3.85,;14.58,2.32,;14.09,.81,;13.05,-.42,;11.42,-.75,;10.09,-1.59,;8.65,-1.01,;8.44,.56,;9.74,1.4,;11.12,.76,;7.33,1.75,;8.07,3.12,;7.34,4.49,;8.22,5.76,;9.52,6.6,;11.07,6.77,;12.56,6.31,;13.76,5.29,;14.97,6.23,;5.77,4.53,;5.03,3.2,;5.75,1.85,;4.93,.56,;3.4,.63,;5.63,-.8,;6.45,.49,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559700 (WO2022109117, Example 45) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3cc(F)cc(OCCCOC(=O)N12)c3 |wD:1.0,3.3,9.33,(17.42,6.56,;16.91,5.12,;17.78,3.87,;16.85,2.66,;17.29,1.2,;18.77,.85,;20.25,.5,;19.12,2.33,;18.41,-.63,;15.42,3.17,;14.81,1.71,;13.66,.63,;12.11,.34,;11.84,1.86,;10.43,2.41,;9.17,1.51,;9.45,-.03,;10.88,-.61,;7.95,2.6,;6.39,2.52,;5.48,3.75,;3.97,3.6,;6.13,5.14,;7.66,5.34,;8.37,6.74,;9.51,7.78,;10.98,8.22,;12.52,8.08,;13.9,7.38,;14.93,6.21,;16.25,6.97,;15.45,4.69,;8.51,4.06,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM559723 (WO2022109117, Example 68) Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3nc(OCCOC(=O)N12)ccc3C(F)(F)F |wD:1.0,3.3,9.29,(-.72,-5.3,;-.34,-3.82,;-1.32,-2.65,;-.5,-1.35,;-1.07,.06,;-2.58,.28,;-4.09,.5,;-2.8,-1.23,;-2.36,1.79,;.98,-1.73,;1.46,-.22,;2.51,1.02,;4.13,1.34,;5.46,2.19,;6.9,1.6,;7.11,.04,;5.81,-.81,;4.43,-.17,;8.22,-1.16,;7.48,-2.52,;8.21,-3.89,;7.33,-5.17,;6.03,-6,;4.48,-6.17,;2.99,-5.72,;1.79,-4.7,;.59,-5.63,;1.08,-3.25,;9.77,-3.93,;10.51,-2.6,;9.8,-1.25,;10.62,.03,;9.92,1.39,;12.14,-.04,;11.32,-1.32,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022109117	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In a typical experiment, the OXI and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q2G
					More data for this Ligand-Target Pair

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