Compile Data Set for Download or QSAR

Found 5 hits of ec50 for UniProtKB: P42680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Tec (Homo sapiens (Human))	BDBM434524 (US10562893, Compound 25) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccc(s3)-c3cnco3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C31H32N6O3S/c1-6-28(38)34-21-8-7-9-22(15-21)37-24-11-10-20(16-33-19(2)31(3,4)5)14-23(24)35-30(37)36-29(39)27-13-12-26(41-27)25-17-32-18-40-25/h6-15,17-19,33H,1,16H2,2-5H3,(H,34,38)(H,35,36,39)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description Tec: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Tec (Homo sapiens (Human))	BDBM434517 (US10562893, Compound 9) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3cccc(c3)C#N)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C31H32N6O2/c1-6-28(38)34-24-11-8-12-25(17-24)37-27-14-13-22(19-33-20(2)31(3,4)5)16-26(27)35-30(37)36-29(39)23-10-7-9-21(15-23)18-32/h6-17,20,33H,1,19H2,2-5H3,(H,34,38)(H,35,36,39)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description Tec: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Tec (Homo sapiens (Human))	BDBM434528 (US10562893, Compound 38) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccno3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C27H30N6O3/c1-6-24(34)30-19-8-7-9-20(15-19)33-22-11-10-18(16-28-17(2)27(3,4)5)14-21(22)31-26(33)32-25(35)23-12-13-29-36-23/h6-15,17,28H,1,16H2,2-5H3,(H,30,34)(H,31,32,35)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description Tec: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Tec (Homo sapiens (Human))	BDBM434526 (US10562893, Compound 28) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccnn3C)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C28H33N7O2/c1-7-25(36)31-20-9-8-10-21(16-20)35-23-12-11-19(17-29-18(2)28(3,4)5)15-22(23)32-27(35)33-26(37)24-13-14-30-34(24)6/h7-16,18,29H,1,17H2,2-6H3,(H,31,36)(H,32,33,37)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description Tec: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Tec (Homo sapiens (Human))	BDBM434515 (US10562893, Compound 2) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccc(s3)C(F)F)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C29H31F2N5O2S/c1-6-25(37)33-19-8-7-9-20(15-19)36-22-11-10-18(16-32-17(2)29(3,4)5)14-21(22)34-28(36)35-27(38)24-13-12-23(39-24)26(30)31/h6-15,17,26,32H,1,16H2,2-5H3,(H,33,37)(H,34,35,38)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description Tec: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair