Compile Data Set for Download or QSAR

Found 1268 hits of ic50 for UniProtKB: P80457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM158057 (US9023882, 356) Show SMILES OC(=O)c1ccc(cc1O)-n1cc(C#N)c(c1)-c1ccco1 Show InChI InChI=1S/C16H10N2O4/c17-7-10-8-18(9-13(10)15-2-1-5-22-15)11-3-4-12(16(20)21)14(19)6-11/h1-6,8-9,19H,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157887 (US9023882, 160) Show SMILES OC(=O)COc1ccc(cc1)-c1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C20H14N2O5/c21-9-15-10-22(16-5-1-14(2-6-16)20(25)26)11-18(15)13-3-7-17(8-4-13)27-12-19(23)24/h1-8,10-11H,12H2,(H,23,24)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157874 (US9023882, 147) Show SMILES OC(=O)c1ccc(cc1)-n1cc(C#N)c(c1)-c1cccc(O)c1 Show InChI InChI=1S/C18H12N2O3/c19-9-14-10-20(15-6-4-12(5-7-15)18(22)23)11-17(14)13-2-1-3-16(21)8-13/h1-8,10-11,21H,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM121552 (US8729273, 22) Show SMILES OC(=O)c1ccnc(c1)-c1ccc2n(CC3CC3)cc(C#N)c2c1 Show InChI InChI=1S/C19H15N3O2/c20-9-15-11-22(10-12-1-2-12)18-4-3-13(7-16(15)18)17-8-14(19(23)24)5-6-21-17/h3-8,11-12H,1-2,10H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences Ltd. US Patent					Assay Description Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...				US Patent US8729273 (2014) BindingDB Entry DOI: 10.7270/Q2D79937
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157944 (US9023882, 233) Show SMILES CC(C)COc1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C16H16N2O3/c1-11(2)10-21-15-9-18(8-13(15)7-17)14-5-3-12(4-6-14)16(19)20/h3-6,8-9,11H,10H2,1-2H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098066 (1-(3-Cyano-4-hydroxy-phenyl)-1H-pyrazole-4-carboxy...) Show SMILES OC(=O)c1cnn(c1)-c1ccc(O)c(c1)C#N Show InChI InChI=1S/C11H7N3O3/c12-4-7-3-9(1-2-10(7)15)14-6-8(5-13-14)11(16)17/h1-3,5-6,15H,(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
South China University of Technology Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidoreductase pre-incubated for 3 mins followed xanthine substrate addition and measured every 1 mins for 10 mins...				Eur J Med Chem 140: 20-30 (2017) Article DOI: 10.1016/j.ejmech.2017.08.047 BindingDB Entry DOI: 10.7270/Q2474DFK
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM158072 (US9023882, 371) Show SMILES OC(=O)c1ccc(nc1)-n1cc(C#N)c(c1)-c1ccccc1 Show InChI InChI=1S/C17H11N3O2/c18-8-14-10-20(11-15(14)12-4-2-1-3-5-12)16-7-6-13(9-19-16)17(21)22/h1-7,9-11H,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157880 (US9023882, 153) Show SMILES OCCOc1cccc(c1)-c1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C20H16N2O4/c21-11-16-12-22(17-6-4-14(5-7-17)20(24)25)13-19(16)15-2-1-3-18(10-15)26-9-8-23/h1-7,10,12-13,23H,8-9H2,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157875 (US9023882, 148) Show SMILES OC(=O)c1ccc(cc1)-n1cc(C#N)c(c1)-c1ccc(O)cc1 Show InChI InChI=1S/C18H12N2O3/c19-9-14-10-20(15-5-1-13(2-6-15)18(22)23)11-17(14)12-3-7-16(21)8-4-12/h1-8,10-11,21H,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157886 (US9023882, 159) Show SMILES OC(=O)COc1cccc(c1)-c1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C20H14N2O5/c21-9-15-10-22(16-6-4-13(5-7-16)20(25)26)11-18(15)14-2-1-3-17(8-14)27-12-19(23)24/h1-8,10-11H,12H2,(H,23,24)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157954 (US9023882, 245) Show SMILES CCCCCc1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C17H18N2O2/c1-2-3-4-5-14-11-19(12-15(14)10-18)16-8-6-13(7-9-16)17(20)21/h6-9,11-12H,2-5H2,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM121532 (US8729273, 2) Show SMILES OC(=O)c1cnn(c1)-c1ccc2n(CC3CC3)cc(C#N)c2c1 Show InChI InChI=1S/C17H14N4O2/c18-6-12-9-20(8-11-1-2-11)16-4-3-14(5-15(12)16)21-10-13(7-19-21)17(22)23/h3-5,7,9-11H,1-2,8H2,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences Ltd. US Patent					Assay Description Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...				US Patent US8729273 (2014) BindingDB Entry DOI: 10.7270/Q2D79937
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50127486 (CHEMBL3628190) Show SMILES CCCCOc1ccc(cc1C#N)-c1nc(C)c(C(O)=O)n1O Show InChI InChI=1S/C16H17N3O4/c1-3-4-7-23-13-6-5-11(8-12(13)9-17)15-18-10(2)14(16(20)21)19(15)22/h5-6,8,22H,3-4,7H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysis				Eur J Med Chem 103: 343-53 (2015) Article DOI: 10.1016/j.ejmech.2015.08.056 BindingDB Entry DOI: 10.7270/Q2X3509Z
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50127441 (CHEMBL3628191) Show SMILES CCC(C)Oc1ccc(cc1C#N)-c1nc(C)c(C(O)=O)n1O Show InChI InChI=1S/C16H17N3O4/c1-4-9(2)23-13-6-5-11(7-12(13)8-17)15-18-10(3)14(16(20)21)19(15)22/h5-7,9,22H,4H2,1-3H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysis				Eur J Med Chem 103: 343-53 (2015) Article DOI: 10.1016/j.ejmech.2015.08.056 BindingDB Entry DOI: 10.7270/Q2X3509Z
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50320491 (2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...) Show SMILES CC(C)COc1ccc(cc1C#N)-c1nc(C)c(s1)C(O)=O Show InChI InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of bovine xanthine oxidase by spectrophotometry				Eur J Med Chem 45: 2663-70 (2010) Article DOI: 10.1016/j.ejmech.2010.02.013 BindingDB Entry DOI: 10.7270/Q2R211KJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157970 (US9023882, 262) Show SMILES OC(=O)c1ccc(cc1)-n1cc(C#N)c(NC(=O)c2ccccc2)n1 Show InChI InChI=1S/C18H12N4O3/c19-10-14-11-22(15-8-6-13(7-9-15)18(24)25)21-16(14)20-17(23)12-4-2-1-3-5-12/h1-9,11H,(H,24,25)(H,20,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50127441 (CHEMBL3628191) Show SMILES CCC(C)Oc1ccc(cc1C#N)-c1nc(C)c(C(O)=O)n1O Show InChI InChI=1S/C16H17N3O4/c1-4-9(2)23-13-6-5-11(7-12(13)8-17)15-18-10(3)14(16(20)21)19(15)22/h5-7,9,22H,4H2,1-3H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysis				Eur J Med Chem 103: 343-53 (2015) Article DOI: 10.1016/j.ejmech.2015.08.056 BindingDB Entry DOI: 10.7270/Q2X3509Z
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM158054 (US9023882, 352) Show SMILES CC(C)(C)c1nn(cc1C#N)-c1ccc(C(O)=O)c(O)c1 Show InChI InChI=1S/C15H15N3O3/c1-15(2,3)13-9(7-16)8-18(17-13)10-4-5-11(14(20)21)12(19)6-10/h4-6,8,19H,1-3H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50127486 (CHEMBL3628190) Show SMILES CCCCOc1ccc(cc1C#N)-c1nc(C)c(C(O)=O)n1O Show InChI InChI=1S/C16H17N3O4/c1-3-4-7-23-13-6-5-11(8-12(13)9-17)15-18-10(2)14(16(20)21)19(15)22/h5-6,8,22H,3-4,7H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysis				Eur J Med Chem 103: 343-53 (2015) Article DOI: 10.1016/j.ejmech.2015.08.056 BindingDB Entry DOI: 10.7270/Q2X3509Z
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311264 (4-(3-(4-methoxy-3-nitrophenyl)-1H-1,2,4-triazol-5-...) Show SMILES COc1ccc(cc1[N+]([O-])=O)-c1nnc([nH]1)-c1ccncc1 Show InChI InChI=1S/C14H11N5O3/c1-22-12-3-2-10(8-11(12)19(20)21)14-16-13(17-18-14)9-4-6-15-7-5-9/h2-8H,1H3,(H,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157950 (US9023882, 240) Show SMILES CCCCc1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C16H16N2O2/c1-2-3-4-13-10-18(11-14(13)9-17)15-7-5-12(6-8-15)16(19)20/h5-8,10-11H,2-4H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM158056 (US9023882, 355) Show SMILES CCCCc1cn(cc1C#N)-c1ccc(C(O)=O)c(O)c1 Show InChI InChI=1S/C16H16N2O3/c1-2-3-4-11-9-18(10-12(11)8-17)13-5-6-14(16(20)21)15(19)7-13/h5-7,9-10,19H,2-4H2,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM121531 (US8729273, 1) Show SMILES CC(C)n1cc(C#N)c2cc(ccc12)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C16H14N4O2/c1-10(2)19-8-11(6-17)14-5-13(3-4-15(14)19)20-9-12(7-18-20)16(21)22/h3-5,7-10H,1-2H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences Ltd. US Patent					Assay Description Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...				US Patent US8729273 (2014) BindingDB Entry DOI: 10.7270/Q2D79937
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098068 (1-[3-CYANO-4-(NEOPENTYLOXY)PHENYL]-1H-PYRAZOLE-4-C...) Show SMILES CC(C)(C)COc1ccc(cc1C#N)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C16H17N3O3/c1-16(2,3)10-22-14-5-4-13(6-11(14)7-17)19-9-12(8-18-19)15(20)21/h4-6,8-9H,10H2,1-3H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
South China University of Technology Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidoreductase pre-incubated for 3 mins followed xanthine substrate addition and measured every 1 mins for 10 mins...				Eur J Med Chem 140: 20-30 (2017) Article DOI: 10.1016/j.ejmech.2017.08.047 BindingDB Entry DOI: 10.7270/Q2474DFK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157948 (US9023882, 238) Show SMILES CCCc1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H14N2O2/c1-2-3-12-9-17(10-13(12)8-16)14-6-4-11(5-7-14)15(18)19/h4-7,9-10H,2-3H2,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157951 (US9023882, 241) Show SMILES CC(C)Cc1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C16H16N2O2/c1-11(2)7-13-9-18(10-14(13)8-17)15-5-3-12(4-6-15)16(19)20/h3-6,9-11H,7H2,1-2H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157953 (US9023882, 244) Show SMILES OC(=O)c1ccc(cc1)-n1cc(C#N)c(c1)-c1ccco1 Show InChI InChI=1S/C16H10N2O3/c17-8-12-9-18(10-14(12)15-2-1-7-21-15)13-5-3-11(4-6-13)16(19)20/h1-7,9-10H,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157938 (US9023882, 227) Show SMILES OC(=O)c1ccc(cc1)-n1cc(C#N)c(c1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C20H15N3O3/c21-10-16-12-23(17-8-6-15(7-9-17)20(25)26)13-18(16)19(24)22-11-14-4-2-1-3-5-14/h1-9,12-13H,11H2,(H,22,24)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50254496 (4-(3-(4-isobutoxy-3-nitrophenyl)-1H-1,2,4-triazol-...) Show SMILES CC(C)COc1ccc(cc1[N+]([O-])=O)-c1nnc([nH]1)-c1ccncc1 Show InChI InChI=1S/C17H17N5O3/c1-11(2)10-25-15-4-3-13(9-14(15)22(23)24)17-19-16(20-21-17)12-5-7-18-8-6-12/h3-9,11H,10H2,1-2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM121536 (US8729273, 6) Show SMILES COCCn1cc(C#N)c2cc(ccc12)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C16H14N4O3/c1-23-5-4-19-9-11(7-17)14-6-13(2-3-15(14)19)20-10-12(8-18-20)16(21)22/h2-3,6,8-10H,4-5H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences Ltd. US Patent					Assay Description Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...				US Patent US8729273 (2014) BindingDB Entry DOI: 10.7270/Q2D79937
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157921 (US9023882, 207) Show SMILES OC(=O)c1ccc(cc1)-n1cc(CCc2ccccc2)c(c1)C#N Show InChI InChI=1S/C20H16N2O2/c21-12-18-14-22(19-10-8-16(9-11-19)20(23)24)13-17(18)7-6-15-4-2-1-3-5-15/h1-5,8-11,13-14H,6-7H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM153045 (US8993616, 191) Show SMILES OC(=O)c1ccc(cc1O)-n1cc(C#N)c2cc(F)ccc12 Show InChI InChI=1S/C16H9FN2O3/c17-10-1-4-14-13(5-10)9(7-18)8-19(14)11-2-3-12(16(21)22)15(20)6-11/h1-6,8,20H,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Test compounds were dissolved in DMSO (Wako) at 40 mM concentration and then diluted to intended concentrations with phosphate-buffered saline (PBS)....				US Patent US8993616 (2015) BindingDB Entry DOI: 10.7270/Q2445K6V
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157992 (US9023882, 285) Show SMILES COc1ccc(cc1OC)-c1cn(cc1C#N)-c1ccc(C(O)=O)c(O)c1 Show InChI InChI=1S/C20H16N2O5/c1-26-18-6-3-12(7-19(18)27-2)16-11-22(10-13(16)9-21)14-4-5-15(20(24)25)17(23)8-14/h3-8,10-11,23H,1-2H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157967 (US9023882, 258) Show SMILES OC(=O)c1ccc(cc1)-n1cc(CCc2ccco2)c(c1)C#N Show InChI InChI=1S/C18H14N2O3/c19-10-15-12-20(16-6-3-13(4-7-16)18(21)22)11-14(15)5-8-17-2-1-9-23-17/h1-4,6-7,9,11-12H,5,8H2,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157879 (US9023882, 152) Show SMILES OCCOc1ccccc1-c1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C20H16N2O4/c21-11-15-12-22(16-7-5-14(6-8-16)20(24)25)13-18(15)17-3-1-2-4-19(17)26-10-9-23/h1-8,12-13,23H,9-10H2,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50240899 (5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3-methoxy-chrom...) Show SMILES COc1c(oc2cc(O)cc(O)c2c1=O)-c1ccc(O)cc1 Show InChI InChI=1S/C16H12O6/c1-21-16-14(20)13-11(19)6-10(18)7-12(13)22-15(16)8-2-4-9(17)5-3-8/h2-7,17-19H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM158040 (US9023882, 337) Show SMILES OC(=O)c1ccc(cc1)-c1cn(cc1C#N)-c1ccc(C(O)=O)c(O)c1 Show InChI InChI=1S/C19H12N2O5/c20-8-13-9-21(14-5-6-15(19(25)26)17(22)7-14)10-16(13)11-1-3-12(4-2-11)18(23)24/h1-7,9-10,22H,(H,23,24)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157873 (US9023882, 146) Show SMILES OC(=O)c1ccc(cc1)-n1cc(C#N)c(c1)-c1ccccc1O Show InChI InChI=1S/C18H12N2O3/c19-9-13-10-20(14-7-5-12(6-8-14)18(22)23)11-16(13)15-3-1-2-4-17(15)21/h1-8,10-11,21H,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50426742 (CHEMBL2322167) Show SMILES CC(C)(C)COc1ccc(cc1C#N)-c1cc(=O)[nH]c(N)n1 Show InChI InChI=1S/C16H18N4O2/c1-16(2,3)9-22-13-5-4-10(6-11(13)8-17)12-7-14(21)20-15(18)19-12/h4-7H,9H2,1-3H3,(H3,18,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Healthcare Limited Curated by ChEMBL					Assay Description Inhibition of bovine xanthine oxidase-mediated uric acid production after 30 mins by spectrophotometric analysis				Bioorg Med Chem Lett 23: 834-8 (2013) Article DOI: 10.1016/j.bmcl.2012.11.057 BindingDB Entry DOI: 10.7270/Q28W3FMN
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157945 (US9023882, 234) Show SMILES COCCOc1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H14N2O4/c1-20-6-7-21-14-10-17(9-12(14)8-16)13-4-2-11(3-5-13)15(18)19/h2-5,9-10H,6-7H2,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157881 (US9023882, 154) Show SMILES OCCOc1ccc(cc1)-c1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C20H16N2O4/c21-11-16-12-22(17-5-1-15(2-6-17)20(24)25)13-19(16)14-3-7-18(8-4-14)26-10-9-23/h1-8,12-13,23H,9-10H2,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157966 (US9023882, 257) Show SMILES CCOc1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C14H12N2O3/c1-2-19-13-9-16(8-11(13)7-15)12-5-3-10(4-6-12)14(17)18/h3-6,8-9H,2H2,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50457198 (CHEMBL4203776) Show SMILES OC(=O)c1cnn(c1)-c1ccc(N2CCCCC2)c(c1)C#N Show InChI InChI=1S/C16H16N4O2/c17-9-12-8-14(20-11-13(10-18-20)16(21)22)4-5-15(12)19-6-2-1-3-7-19/h4-5,8,10-11H,1-3,6-7H2,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
South China University of Technology Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidoreductase pre-incubated for 3 mins followed xanthine substrate addition and measured every 1 mins for 10 mins...				Eur J Med Chem 140: 20-30 (2017) Article DOI: 10.1016/j.ejmech.2017.08.047 BindingDB Entry DOI: 10.7270/Q2474DFK
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM153046 (US8993616, 192) Show SMILES OC(=O)c1ccc(cc1O)-n1cc(C#N)c2ccc(F)cc12 Show InChI InChI=1S/C16H9FN2O3/c17-10-1-3-12-9(7-18)8-19(14(12)5-10)11-2-4-13(16(21)22)15(20)6-11/h1-6,8,20H,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Test compounds were dissolved in DMSO (Wako) at 40 mM concentration and then diluted to intended concentrations with phosphate-buffered saline (PBS)....				US Patent US8993616 (2015) BindingDB Entry DOI: 10.7270/Q2445K6V
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM158042 (US9023882, 339) Show SMILES OC(=O)c1ccc(cc1O)-n1cc(C#N)c(c1)-c1ccc(O)cc1 Show InChI InChI=1S/C18H12N2O4/c19-8-12-9-20(10-16(12)11-1-4-14(21)5-2-11)13-3-6-15(18(23)24)17(22)7-13/h1-7,9-10,21-22H,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM121534 (US8729273, 4) Show SMILES CC(C)Cn1cc(C#N)c2cc(ccc12)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C17H16N4O2/c1-11(2)8-20-9-12(6-18)15-5-14(3-4-16(15)20)21-10-13(7-19-21)17(22)23/h3-5,7,9-11H,8H2,1-2H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences Ltd. US Patent					Assay Description Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...				US Patent US8729273 (2014) BindingDB Entry DOI: 10.7270/Q2D79937
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157939 (US9023882, 228) Show SMILES CN(Cc1ccccc1)C(=O)c1cn(cc1C#N)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C21H17N3O3/c1-23(12-15-5-3-2-4-6-15)20(25)19-14-24(13-17(19)11-22)18-9-7-16(8-10-18)21(26)27/h2-10,13-14H,12H2,1H3,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM157925 (US9023882, 211) Show SMILES OC(=O)c1ccc(cc1)-n1cc(C#N)c(c1)-c1cccc(c1)C#N Show InChI InChI=1S/C19H11N3O2/c20-9-13-2-1-3-15(8-13)18-12-22(11-16(18)10-21)17-6-4-14(5-7-17)19(23)24/h1-8,11-12H,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	25
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...				US Patent US9023882 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CM6
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM121547 (US8729273, 17) Show SMILES CC(C)n1cc([N+]([O-])=O)c2cc(ccc12)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C15H14N4O4/c1-9(2)17-8-14(19(22)23)12-5-11(3-4-13(12)17)18-7-10(6-16-18)15(20)21/h3-9H,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences Ltd. US Patent					Assay Description Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...				US Patent US8729273 (2014) BindingDB Entry DOI: 10.7270/Q2D79937
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM121539 (US8729273, 9) Show SMILES OC(=O)c1cnn(c1)-c1ccc2n(cc(C#N)c2c1)C1CCCC1 Show InChI InChI=1S/C18H16N4O2/c19-8-12-10-21(14-3-1-2-4-14)17-6-5-15(7-16(12)17)22-11-13(9-20-22)18(23)24/h5-7,9-11,14H,1-4H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences Ltd. US Patent					Assay Description Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...				US Patent US8729273 (2014) BindingDB Entry DOI: 10.7270/Q2D79937
					More data for this Ligand-Target Pair

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