Compile Data Set for Download or QSAR

Found 563 hits of ic50 for UniProtKB: P15207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Rattus norvegicus (Rat))	BDBM112830 (US8629167, 41) Show SMILES C[C@@H](O)C(Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(F)c(O)c1 |r| Show InChI InChI=1S/C19H16ClFN4O3/c1-9-13(6-7-14(22-3)16(9)20)23-17(10(2)26)19-25-24-18(28-19)11-4-5-12(21)15(27)8-11/h4-8,10,17,23,26-27H,1-2H3/t10-,17?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112818 (US8629167, 29) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(O)c(F)c1 |r| Show InChI InChI=1S/C19H16ClFN4O3/c1-9-13(5-6-14(22-3)16(9)20)23-17(10(2)26)19-25-24-18(28-19)11-4-7-15(27)12(21)8-11/h4-8,10,17,23,26-27H,1-2H3/t10-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112828 (US8629167, 39) Show SMILES C[C@@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C19H15ClF2N4O2/c1-9-14(6-7-15(23-3)16(9)20)24-17(10(2)27)19-26-25-18(28-19)11-4-5-12(21)13(22)8-11/h4-8,10,17,24,27H,1-2H3/t10-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112829 (US8629167, 40) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(F)c(O)c1 |r| Show InChI InChI=1S/C19H16ClFN4O3/c1-9-13(6-7-14(22-3)16(9)20)23-17(10(2)26)19-25-24-18(28-19)11-4-5-12(21)15(27)8-11/h4-8,10,17,23,26-27H,1-2H3/t10-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112826 (US8629167, 37) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(O)c(Cl)c1 |r| Show InChI InChI=1S/C19H16Cl2N4O3/c1-9-13(5-6-14(22-3)16(9)21)23-17(10(2)26)19-25-24-18(28-19)11-4-7-15(27)12(20)8-11/h4-8,10,17,23,26-27H,1-2H3/t10-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112824 (US8629167, 35) Show SMILES C[C@@H](O)[C@@H](Nc1ccc(C#N)c(Cl)c1C)c1nnc(o1)-c1ccc(F)cc1F |r| Show InChI InChI=1S/C19H15ClF2N4O2/c1-9-15(6-3-11(8-23)16(9)20)24-17(10(2)27)19-26-25-18(28-19)13-5-4-12(21)7-14(13)22/h3-7,10,17,24,27H,1-2H3/t10-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112819 (US8629167, 30) Show SMILES C[C@@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(O)c(Cl)c1 |r| Show InChI InChI=1S/C19H16Cl2N4O3/c1-9-13(5-6-14(22-3)16(9)21)23-17(10(2)26)19-25-24-18(28-19)11-4-7-15(27)12(20)8-11/h4-8,10,17,23,26-27H,1-2H3/t10-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112797 (US8629167, 7) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1cccc(O)c1 |r| Show InChI InChI=1S/C19H17ClN4O3/c1-10-14(7-8-15(21-3)16(10)20)22-17(11(2)25)19-24-23-18(27-19)12-5-4-6-13(26)9-12/h4-9,11,17,22,25-26H,1-2H3/t11-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112805 (US8629167, 15) Show SMILES Cc1c(N[C@@H](c2nnc(o2)-c2ccc(Cl)cc2)C(C)(C)O)ccc([N+]#[C-])c1Cl |r| Show InChI InChI=1S/C20H18Cl2N4O2/c1-11-14(9-10-15(23-4)16(11)22)24-17(20(2,3)27)19-26-25-18(28-19)12-5-7-13(21)8-6-12/h5-10,17,24,27H,1-3H3/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112812 (US8629167, 23) Show SMILES C[C@@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C20H16ClN5O2/c1-11-15(8-9-16(23-3)17(11)21)24-18(12(2)27)20-26-25-19(28-20)14-6-4-13(10-22)5-7-14/h4-9,12,18,24,27H,1-2H3/t12-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112841 (US8629167, 53) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(cc1)-n1cccn1 |r| Show InChI InChI=1S/C22H19ClN6O2/c1-13-17(9-10-18(24-3)19(13)23)26-20(14(2)30)22-28-27-21(31-22)15-5-7-16(8-6-15)29-12-4-11-25-29/h4-12,14,20,26,30H,1-2H3/t14-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112836 (US8629167, 47) Show SMILES CCc1c(N[C@H]([C@H](C)O)C2=NOC(O2)c2ccc(cc2)C#N)ccc(C#N)c1Cl |r,t:9| Show InChI InChI=1S/C21H19ClN4O3/c1-3-16-17(9-8-15(11-24)18(16)22)25-19(12(2)27)20-26-29-21(28-20)14-6-4-13(10-23)5-7-14/h4-9,12,19,21,25,27H,3H2,1-2H3/t12-,19+,21?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112882 (US8629167, 95) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c2scc(Cl)c12)c1nnc(o1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C21H14ClN5O2S/c1-11(28)18(21-27-26-20(29-21)13-5-3-12(9-23)4-6-13)25-15-7-8-16(24-2)19-17(15)14(22)10-30-19/h3-8,10-11,18,25,28H,1H3/t11-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112867 (US8629167, 80) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C=C)c1nnc(o1)-c1ccc(cc1)[N+]#[C-] |r| Show InChI InChI=1S/C21H16ClN5O2/c1-5-15-16(10-11-17(24-4)18(15)22)25-19(12(2)28)21-27-26-20(29-21)13-6-8-14(23-3)9-7-13/h5-12,19,25,28H,1H2,2H3/t12-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM18161 ((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C |r| Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00943 BindingDB Entry DOI: 10.7270/Q2DV1PHB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Rattus norvegicus (Rat))	BDBM112842 (US8629167, 54) Show SMILES CCc1c(N[C@H]([C@@H](C)O)c2nnc(o2)-c2ccc(cc2)[N+]#[C-])ccc([N+]#[C-])c1Cl |r| Show InChI InChI=1S/C21H18ClN5O2/c1-5-15-16(10-11-17(24-4)18(15)22)25-19(12(2)28)21-27-26-20(29-21)13-6-8-14(23-3)9-7-13/h6-12,19,25,28H,5H2,1-2H3/t12-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112853 (US8629167, 65) Show SMILES C[C@@H](O)[C@@H](Nc1ccc([N+]#[C-])c2sccc12)c1nnc(o1)-c1ccccc1 |r| Show InChI InChI=1S/C20H16N4O2S/c1-12(25)17(20-24-23-19(26-20)13-6-4-3-5-7-13)22-15-8-9-16(21-2)18-14(15)10-11-27-18/h3-12,17,22,25H,1H3/t12-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM26258 ((1S,2R,9R,10R,11S,14S,15S)-14-hydroxy-9,14,15-trim...) Show SMILES [H][C@@]12CC[C@](C)(O)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3C[C@@H](C)[C@@]21[H] |c:20| Show InChI InChI=1S/C20H30O2/c1-12-10-13-11-14(21)4-5-15(13)16-6-8-19(2)17(18(12)16)7-9-20(19,3)22/h11-12,15-18,22H,4-10H2,1-3H3/t12-,15+,16-,17+,18-,19+,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional Aut£noma de M£xico Curated by ChEMBL					Assay Description Displacement of [3H]-MIB from rat prostate cytosolic androgen receptor by liquid scintillation counting method				Bioorg Med Chem 25: 1600-1607 (2017) Article DOI: 10.1016/j.bmc.2017.01.018 BindingDB Entry DOI: 10.7270/Q27D2XCS
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112852 (US8629167, 64) Show SMILES C[C@@H](O)[C@@H](Nc1ccc([N+]#[C-])c2sccc12)c1nnc(o1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C20H15FN4O2S/c1-11(26)17(20-25-24-19(27-20)12-3-5-13(21)6-4-12)23-15-7-8-16(22-2)18-14(15)9-10-28-18/h3-11,17,23,26H,1H3/t11-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112851 (US8629167, 63) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c2sccc12)c1nnc(o1)-c1ccccc1 |r| Show InChI InChI=1S/C20H16N4O2S/c1-12(25)17(20-24-23-19(26-20)13-6-4-3-5-7-13)22-15-8-9-16(21-2)18-14(15)10-11-27-18/h3-12,17,22,25H,1H3/t12-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112849 (US8629167, 61) Show SMILES C[C@@H](O)[C@@H](Nc1ccc([N+]#[C-])c2sccc12)c1nnc(o1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C21H15N5O2S/c1-12(27)18(24-16-7-8-17(23-2)19-15(16)9-10-29-19)21-26-25-20(28-21)14-5-3-13(11-22)4-6-14/h3-10,12,18,24,27H,1H3/t12-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112865 (US8629167, 78) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(NC(C)=O)cc1 |r| Show InChI InChI=1S/C21H20ClN5O3/c1-11-16(9-10-17(23-4)18(11)22)25-19(12(2)28)21-27-26-20(30-21)14-5-7-15(8-6-14)24-13(3)29/h5-10,12,19,25,28H,1-3H3,(H,24,29)/t12-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM50367916 (METHYLTRIENOLONE | Metribolone | R-1881) Show SMILES C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3C=C[C@]12C |r,c:16,19,t:9| Show InChI InChI=1S/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of rat AR-mediated reporter gene expression in COS7 cells				Bioorg Med Chem Lett 16: 3233-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.047 BindingDB Entry DOI: 10.7270/Q2Q52QDP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Rattus norvegicus (Rat))	BDBM50025425 (17-Hydroxy-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2CC(=O)C=C[C@]12C |r,c:22| Show InChI InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,12,14-17,21H,3-6,8,10-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR)				J Med Chem 29: 2298-315 (1986) BindingDB Entry DOI: 10.7270/Q2XG9RQR
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM50367916 (METHYLTRIENOLONE | Metribolone | R-1881) Show SMILES C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3C=C[C@]12C |r,c:16,19,t:9| Show InChI InChI=1S/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00716 BindingDB Entry DOI: 10.7270/Q2J1076H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Rattus norvegicus (Rat))	BDBM26258 ((1S,2R,9R,10R,11S,14S,15S)-14-hydroxy-9,14,15-trim...) Show SMILES [H][C@@]12CC[C@](C)(O)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3C[C@@H](C)[C@@]21[H] |c:20| Show InChI InChI=1S/C20H30O2/c1-12-10-13-11-14(21)4-5-15(13)16-6-8-19(2)17(18(12)16)7-9-20(19,3)22/h11-12,15-18,22H,4-10H2,1-3H3/t12-,15+,16-,17+,18-,19+,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.66	n/a	n/a	n/a	n/a	n/a	n/a
University of Basel Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)				J Med Chem 48: 5666-74 (2005) Article DOI: 10.1021/jm050403f BindingDB Entry DOI: 10.7270/Q2TM7CBZ
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM18161 ((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C |r| Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]testosterone from androgen receptor in Sprague-Dawley rat prostate gland after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 21: 6310-3 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2011.08.118 BindingDB Entry DOI: 10.7270/Q2JH3MKZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Rattus norvegicus (Rat))	BDBM112868 (US8629167, 81) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1cccc(F)c1 |r| Show InChI InChI=1S/C19H16ClFN4O2/c1-10-14(7-8-15(22-3)16(10)20)23-17(11(2)26)19-25-24-18(27-19)12-5-4-6-13(21)9-12/h4-9,11,17,23,26H,1-2H3/t11-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112866 (US8629167, 79) Show SMILES Cc1c(N[C@H](CCO)c2nnc(o2)-c2ccc(cc2)[N+]#[C-])ccc([N+]#[C-])c1Cl |r| Show InChI InChI=1S/C20H16ClN5O2/c1-12-15(8-9-16(23-3)18(12)21)24-17(10-11-27)20-26-25-19(28-20)13-4-6-14(22-2)7-5-13/h4-9,17,24,27H,10-11H2,1H3/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112885 (US8629167, 49) Show SMILES C[C@@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(CO)cc1 |r| Show InChI InChI=1S/C20H19ClN4O3/c1-11-15(8-9-16(22-3)17(11)21)23-18(12(2)27)20-25-24-19(28-20)14-6-4-13(10-26)5-7-14/h4-9,12,18,23,26-27H,10H2,1-2H3/t12-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112821 (US8629167, 32) Show SMILES C[C@@H](O)C(Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H15Cl3N4O2/c1-9-14(6-7-15(23-3)16(9)22)24-17(10(2)27)19-26-25-18(28-19)11-4-5-12(20)13(21)8-11/h4-8,10,17,24,27H,1-2H3/t10-,17?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112811 (US8629167, 22) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C20H16ClN5O2/c1-11-15(8-9-16(23-3)17(11)21)24-18(12(2)27)20-26-25-19(28-20)14-6-4-13(10-22)5-7-14/h4-9,12,18,24,27H,1-2H3/t12-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM18161 ((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C |r| Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR)				J Med Chem 29: 2298-315 (1986) BindingDB Entry DOI: 10.7270/Q2XG9RQR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Rattus norvegicus (Rat))	BDBM50410541 (CHEMBL194467) Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC(=O)CC[C@]34C)[C@@H]1CC[C@H]2O Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17+,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.24	n/a	n/a	n/a	n/a	n/a	n/a
University of Basel Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)				J Med Chem 48: 5666-74 (2005) Article DOI: 10.1021/jm050403f BindingDB Entry DOI: 10.7270/Q2TM7CBZ
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM50025417 (7-Hydroxy-1,4a,6a-trimethyl-1,4a,4b,5,6,6a,7,8,9,9...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])N(C)C(=O)C=C[C@]12C |r,c:24| Show InChI InChI=1S/C19H29NO2/c1-18-11-9-17(22)20(3)15(18)6-4-12-13-5-7-16(21)19(13,2)10-8-14(12)18/h9,11-16,21H,4-8,10H2,1-3H3/t12?,13?,14?,15-,16?,18?,19?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR)				J Med Chem 29: 2298-315 (1986) BindingDB Entry DOI: 10.7270/Q2XG9RQR
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM50410489 (TRENBOLONE) Show SMILES C[C@]12C=CC3=C4CCC(=O)C=C4CCC3C1CC[C@@H]2O |c:2,4,10| Show InChI InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h8-10,15-17,20H,2-7H2,1H3/t15?,16?,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.63	n/a	n/a	n/a	n/a	n/a	n/a
University of Basel Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)				J Med Chem 48: 5666-74 (2005) Article DOI: 10.1021/jm050403f BindingDB Entry DOI: 10.7270/Q2TM7CBZ
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112810 (US8629167, 21) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C19H16Cl2N4O2/c1-10-14(7-8-15(22-3)16(10)21)23-17(11(2)26)19-25-24-18(27-19)12-5-4-6-13(20)9-12/h4-9,11,17,23,26H,1-2H3/t11-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112791 (US8629167, 1) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccccc1 |r| Show InChI InChI=1S/C19H17ClN4O2/c1-11-14(9-10-15(21-3)16(11)20)22-17(12(2)25)19-24-23-18(26-19)13-7-5-4-6-8-13/h4-10,12,17,22,25H,1-2H3/t12-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112832 (US8629167, 43) Show SMILES C[C@H](O)C(Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(C)o1 |r| Show InChI InChI=1S/C14H15ClN4O2/c1-7-10(5-6-11(16-4)12(7)15)17-13(8(2)20)14-19-18-9(3)21-14/h5-6,8,13,17,20H,1-3H3/t8-,13?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM50367916 (METHYLTRIENOLONE | Metribolone | R-1881) Show SMILES C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3C=C[C@]12C |r,c:16,19,t:9| Show InChI InChI=1S/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	3.09	n/a	n/a	n/a	n/a	n/a	n/a
University of Basel Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)				J Med Chem 48: 5666-74 (2005) Article DOI: 10.1021/jm050403f BindingDB Entry DOI: 10.7270/Q2TM7CBZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Rattus norvegicus (Rat))	BDBM18161 ((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C |r| Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Competitive binding affinity to rat androgen receptor				Bioorg Med Chem Lett 21: 6310-3 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2011.08.118 BindingDB Entry DOI: 10.7270/Q2JH3MKZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Rattus norvegicus (Rat))	BDBM18161 ((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C |r| Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]testosterone from Sprague-Dawley rat AR by liquid scintillation counting				Bioorg Med Chem Lett 21: 1744-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.073 BindingDB Entry DOI: 10.7270/Q2474B55
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Rattus norvegicus (Rat))	BDBM8885 ((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C |r,t:18| Show InChI InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR)				J Med Chem 29: 2298-315 (1986) BindingDB Entry DOI: 10.7270/Q2XG9RQR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Rattus norvegicus (Rat))	BDBM112823 (US8629167, 34) Show SMILES C[C@H](O)[C@@H](Nc1ccc(C#N)c(Cl)c1Cl)c1nnc(o1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C18H13Cl3N4O2/c1-9(26)16(23-13-7-4-11(8-22)14(20)15(13)21)18-25-24-17(27-18)10-2-5-12(19)6-3-10/h2-7,9,16,23,26H,1H3/t9-,16+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112858 (US8629167, 70) Show SMILES C[C@@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(NC(C)=O)cc1 |r| Show InChI InChI=1S/C21H20ClN5O3/c1-11-16(9-10-17(23-4)18(11)22)25-19(12(2)28)21-27-26-20(30-21)14-5-7-15(8-6-14)24-13(3)29/h5-10,12,19,25,28H,1-3H3,(H,24,29)/t12-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM180890 (US9133182, Example 19) Show SMILES C[C@@H]1OC(=O)N([C@H]1[C@H](O)C(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C14H10F6N2O3/c1-6-10(11(23)14(18,19)20)22(12(24)25-6)8-3-2-7(5-21)9(4-8)13(15,16)17/h2-4,6,10-11,23H,1H3/t6-,10+,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US9133182 (2015) BindingDB Entry DOI: 10.7270/Q2JD4VK6
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112803 (US8629167, 13) Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c2ccccc12)c1nnc(o1)-c1ccccc1 |r| Show InChI InChI=1S/C22H18N4O2/c1-14(27)20(22-26-25-21(28-22)15-8-4-3-5-9-15)24-19-13-12-18(23-2)16-10-6-7-11-17(16)19/h3-14,20,24,27H,1H3/t14-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112833 (US8629167, 44) Show SMILES C[C@@H](O)[C@@H](Nc1ccc(C#N)c(c1)C(F)(F)F)c1nnc(o1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C20H14F3N5O2/c1-11(29)17(26-15-7-6-14(10-25)16(8-15)20(21,22)23)19-28-27-18(30-19)13-4-2-12(9-24)3-5-13/h2-8,11,17,26,29H,1H3/t11-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112792 (US8629167, 2) Show SMILES COc1ccc(cc1)-c1nnc(o1)[C@H](Nc1ccc([N+]#[C-])c(Cl)c1C)[C@H](C)O |r| Show InChI InChI=1S/C20H19ClN4O3/c1-11-15(9-10-16(22-3)17(11)21)23-18(12(2)26)20-25-24-19(28-20)13-5-7-14(27-4)8-6-13/h5-10,12,18,23,26H,1-2,4H3/t12-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM112838 (US8629167, 50) Show SMILES C[C@H](O)[C@@H](Nc1ccc(C#N)c(Cl)c1)c1nnc(o1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C19H14ClN5O2/c1-11(26)17(23-15-7-6-14(10-22)16(20)8-15)19-25-24-18(27-19)13-4-2-12(9-21)3-5-13/h2-8,11,17,23,26H,1H3/t11-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Radius Health, Inc. US Patent					Assay Description In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...				US Patent US8629167 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KTX
					More data for this Ligand-Target Pair

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