Compile Data Set for Download or QSAR

Found 1061 hits of ic50 for UniProtKB: P05771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition Protein kinase C (PKC)				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair				3D Structure (crystal)
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519062 (CHEMBL4442196) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](OC(C)=O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:41:57.58:38,THB:62:43:57.58:38,45:43:57.58:38,56:57:43.41.44:38,32:37:45.57.56:41| Show InChI InChI=1S/C46H56O13/c1-25(2)42-22-31(23-53-39(49)29-17-11-8-12-18-29)45-34-37(42)57-46(58-42,59-45)32(54-28(5)48)21-15-7-6-10-16-26(3)33-27(4)36(55-40(50)30-19-13-9-14-20-30)44(52,35(33)45)41(51)43(24-47)38(34)56-43/h8-9,11-14,17-20,26-27,31-38,41,47,51-52H,1,6-7,10,15-16,21-24H2,2-5H3/t26-,27+,31+,32-,33+,34-,35-,36+,37-,38+,41-,42-,43+,44-,45-,46?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519087 (CHEMBL3741746) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:38:35:54.55,THB:55:34:38:54.53.42,32:34:38:54.53.42,53:54:40.38.41:35,42:40:35:54.55,56:54:40.38.41:35| Show InChI InChI=1S/C44H54O12/c1-24(2)40-21-29(22-51-37(47)27-16-10-7-11-17-27)43-32-35(40)54-44(55-40,56-43)30(46)20-14-6-5-9-15-25(3)31-26(4)34(52-38(48)28-18-12-8-13-19-28)42(50,33(31)43)39(49)41(23-45)36(32)53-41/h7-8,10-13,16-19,25-26,29-36,39,45-46,49-50H,1,5-6,9,14-15,20-23H2,2-4H3/t25-,26+,29+,30-,31+,32-,33-,34+,35-,36+,39-,40-,41+,42-,43-,44?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519068 (CHEMBL4575056) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCCC(=O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:38:54.55:35,THB:59:40:54.55:35,42:40:54.55:35,53:54:40.38.41:35,32:34:42.54.53:38| Show InChI InChI=1S/C44H52O12/c1-24(2)40-21-29(22-51-37(47)27-16-10-7-11-17-27)43-32-35(40)54-44(55-40,56-43)30(46)20-14-6-5-9-15-25(3)31-26(4)34(52-38(48)28-18-12-8-13-19-28)42(50,33(31)43)39(49)41(23-45)36(32)53-41/h7-8,10-13,16-19,25-26,29,31-36,39,45,49-50H,1,5-6,9,14-15,20-23H2,2-4H3/t25-,26+,29+,31+,32-,33-,34+,35-,36+,39-,40-,41+,42-,43-,44?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519060 (CHEMBL4528495) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccc4ccccc4c3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:42:58.59:39,THB:63:44:58.59:39,36:38:46.58.57:42,46:44:58.59:39,57:58:44.42.45:39| Show InChI InChI=1S/C48H56O12/c1-26(2)44-23-33(24-55-41(51)30-16-9-7-10-17-30)47-36-39(44)58-48(59-44,60-47)34(50)19-11-6-5-8-14-27(3)35-28(4)38(46(54,37(35)47)43(53)45(25-49)40(36)57-45)56-42(52)32-21-20-29-15-12-13-18-31(29)22-32/h7,9-10,12-13,15-18,20-22,27-28,33-40,43,49-50,53-54H,1,5-6,8,11,14,19,23-25H2,2-4H3/t27-,28+,33+,34-,35+,36-,37-,38+,39-,40+,43-,44-,45+,46-,47-,48?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519083 (CHEMBL4538431) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccc(OC)cc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:40:56.57:37,THB:61:42:56.57:37,44:42:56.57:37,55:56:42.40.43:37,34:36:44.56.55:40| Show InChI InChI=1S/C45H56O13/c1-24(2)41-21-29(22-53-38(48)27-14-10-8-11-15-27)44-33-36(41)56-45(57-41,58-44)31(47)16-12-7-6-9-13-25(3)32-26(4)35(54-39(49)28-17-19-30(52-5)20-18-28)43(51,34(32)44)40(50)42(23-46)37(33)55-42/h8,10-11,14-15,17-20,25-26,29,31-37,40,46-47,50-51H,1,6-7,9,12-13,16,21-23H2,2-5H3/t25-,26+,29+,31-,32+,33-,34-,35+,36-,37+,40-,41-,42+,43-,44-,45?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519084 (CHEMBL4443190) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)C)[C@@]13[H] |r,TLB:1:38:54.55:35,THB:59:40:54.55:35,42:40:54.55:35,53:54:40.38.41:35,32:34:42.54.53:38| Show InChI InChI=1S/C44H56O12/c1-24(2)40-21-29(22-51-37(47)27-16-10-7-11-17-27)43-32-35(40)54-44(55-40,56-43)30(46)20-14-6-5-9-15-25(3)31-26(4)34(52-38(48)28-18-12-8-13-19-28)42(50,33(31)43)39(49)41(23-45)36(32)53-41/h7-8,10-13,16-19,24-26,29-36,39,45-46,49-50H,5-6,9,14-15,20-23H2,1-4H3/t25-,26+,29+,30-,31+,32-,33-,34+,35-,36+,39-,40-,41+,42-,43-,44?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50393214 (CHEMBL2151411) Show SMILES CN1CCN(CC1)c1nc(C2=C(C(=O)NC2=O)c2c[nH]c3c(C)cccc23)c2ccccc2n1 |t:11| Show InChI InChI=1S/C26H24N6O2/c1-15-6-5-8-16-18(14-27-22(15)16)20-21(25(34)30-24(20)33)23-17-7-3-4-9-19(17)28-26(29-23)32-12-10-31(2)11-13-32/h3-9,14,27H,10-13H2,1-2H3,(H,30,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PKCbeta-1 by scintillation proximity assay				J Med Chem 54: 6028-39 (2011) Article DOI: 10.1021/jm200469u BindingDB Entry DOI: 10.7270/Q2K35VR1
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519069 (CHEMBL4435580) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccc(cc3)[N+]([O-])=O)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:41:57.58:38,THB:62:43:57.58:38,45:43:57.58:38,56:57:43.41.44:38,35:37:45.57.56:41| Show InChI InChI=1S/C44H53NO14/c1-23(2)40-20-28(21-54-37(48)26-13-9-7-10-14-26)43-32-35(40)57-44(58-40,59-43)30(47)15-11-6-5-8-12-24(3)31-25(4)34(55-38(49)27-16-18-29(19-17-27)45(52)53)42(51,33(31)43)39(50)41(22-46)36(32)56-41/h7,9-10,13-14,16-19,24-25,28,30-36,39,46-47,50-51H,1,5-6,8,11-12,15,20-22H2,2-4H3/t24-,25+,28+,30-,31+,32-,33-,34+,35-,36+,39-,40-,41+,42-,43-,44?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519063 (CHEMBL4587471) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccncc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:38:54.55:35,THB:59:40:54.55:35,42:40:54.55:35,53:54:40.38.41:35,32:34:42.54.53:38| Show InChI InChI=1S/C43H53NO12/c1-23(2)39-20-28(21-51-36(47)26-13-9-7-10-14-26)42-31-34(39)54-43(55-39,56-42)29(46)15-11-6-5-8-12-24(3)30-25(4)33(52-37(48)27-16-18-44-19-17-27)41(50,32(30)42)38(49)40(22-45)35(31)53-40/h7,9-10,13-14,16-19,24-25,28-35,38,45-46,49-50H,1,5-6,8,11-12,15,20-22H2,2-4H3/t24-,25+,28+,29-,30+,31-,32-,33+,34-,35+,38-,39-,40+,41-,42-,43?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of protein kinase C				Citation and Details BindingDB Entry DOI: 10.7270/Q27946V3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein kinase C beta type (Homo sapiens (Human))	BDBM50393218 (CHEMBL1996510) Show SMILES O=C1NC(=O)C(=C1c1c[nH]c2ccccc12)c1nc(nc2ccccc12)N1CCNCC1 |c:5| Show InChI InChI=1S/C24H20N6O2/c31-22-19(16-13-26-17-7-3-1-5-14(16)17)20(23(32)29-22)21-15-6-2-4-8-18(15)27-24(28-21)30-11-9-25-10-12-30/h1-8,13,25-26H,9-12H2,(H,29,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PKCbeta-1 by scintillation proximity assay				J Med Chem 54: 6028-39 (2011) Article DOI: 10.1021/jm200469u BindingDB Entry DOI: 10.7270/Q2K35VR1
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM33971 (AEB071 | Sotrastaurin | med.21724, Compound 190) Show SMILES CN1CCN(CC1)c1nc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc2n1 |t:11| Show InChI InChI=1S/C25H22N6O2/c1-30-10-12-31(13-11-30)25-27-19-9-5-3-7-16(19)22(28-25)21-20(23(32)29-24(21)33)17-14-26-18-8-4-2-6-15(17)18/h2-9,14,26H,10-13H2,1H3,(H,29,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01031 BindingDB Entry DOI: 10.7270/Q2FF3XF8
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50235283 (CHEMBL4102228) Show SMILES CN(C)Cc1ccc2ccc(Cl)c(C3=C(C(=O)NC3=O)c3c[nH]c4ccccc34)c2c1 |t:13| Show InChI InChI=1S/C25H20ClN3O2/c1-29(2)13-14-7-8-15-9-10-19(26)21(17(15)11-14)23-22(24(30)28-25(23)31)18-12-27-20-6-4-3-5-16(18)20/h3-12,27H,13H2,1-2H3,(H,28,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PKCbeta1 (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assay				Bioorg Med Chem Lett 27: 781-786 (2017) Article DOI: 10.1016/j.bmcl.2017.01.038 BindingDB Entry DOI: 10.7270/Q2930WF1
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519067 (CHEMBL4443186) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](OC(=O)C(\C)=C\C)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:44:60.61:41,THB:65:46:60.61:41,48:46:60.61:41,59:60:46.44.47:41,32:40:48.60.59:44| Show InChI InChI=1S/C49H60O13/c1-7-28(4)41(51)57-34-23-17-9-8-12-18-29(5)35-30(6)38(58-43(53)32-21-15-11-16-22-32)47(55)37(35)48-33(25-56-42(52)31-19-13-10-14-20-31)24-45(27(2)3)39(60-49(34,61-45)62-48)36(48)40-46(26-50,59-40)44(47)54/h7,10-11,13-16,19-22,29-30,33-40,44,50,54-55H,2,8-9,12,17-18,23-26H2,1,3-6H3/b28-7+/t29-,30+,33+,34-,35+,36-,37-,38+,39-,40+,44-,45-,46+,47-,48-,49?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519070 (CHEMBL4580586) Show SMILES [H][C@@]12O[C@]1(COC(C)=O)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:41:57.58:38,THB:62:43:57.58:38,45:43:57.58:38,56:57:43.41.44:38,35:37:45.57.56:41| Show InChI InChI=1S/C46H56O13/c1-25(2)42-22-31(23-53-39(49)29-17-11-8-12-18-29)45-34-37(42)57-46(58-42,59-45)32(48)21-15-7-6-10-16-26(3)33-27(4)36(55-40(50)30-19-13-9-14-20-30)44(52,35(33)45)41(51)43(38(34)56-43)24-54-28(5)47/h8-9,11-14,17-20,26-27,31-38,41,48,51-52H,1,6-7,10,15-16,21-24H2,2-5H3/t26-,27+,31+,32-,33+,34-,35-,36+,37-,38+,41-,42-,43+,44-,45-,46?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519066 (CHEMBL4460926) Show SMILES [H][C@@]12O[C@]1(COC(=O)CCC(O)=O)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:45:61.62:42,THB:66:47:61.62:42,49:47:61.62:42,60:61:47.45.48:42,39:41:49.61.60:45| Show InChI InChI=1S/C48H58O15/c1-26(2)44-23-31(24-57-41(53)29-16-10-7-11-17-29)47-36-39(44)61-48(62-44,63-47)32(49)20-14-6-5-9-15-27(3)35-28(4)38(59-42(54)30-18-12-8-13-19-30)46(56,37(35)47)43(55)45(40(36)60-45)25-58-34(52)22-21-33(50)51/h7-8,10-13,16-19,27-28,31-32,35-40,43,49,55-56H,1,5-6,9,14-15,20-25H2,2-4H3,(H,50,51)/t27-,28+,31+,32-,35+,36-,37-,38+,39-,40+,43-,44-,45+,46-,47-,48?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519065 (CHEMBL4578026) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](OC(=O)c4ccccc4)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:46:62.63:43,THB:67:48:62.63:43,50:48:62.63:43,61:62:48.46.49:43,32:42:50.62.61:46| Show InChI InChI=1S/C51H58O13/c1-29(2)47-26-35(27-58-43(53)32-19-11-7-12-20-32)50-38-41(47)62-51(63-47,64-50)36(59-44(54)33-21-13-8-14-22-33)25-17-6-5-10-18-30(3)37-31(4)40(60-45(55)34-23-15-9-16-24-34)49(57,39(37)50)46(56)48(28-52)42(38)61-48/h7-9,11-16,19-24,30-31,35-42,46,52,56-57H,1,5-6,10,17-18,25-28H2,2-4H3/t30-,31+,35+,36-,37+,38-,39-,40+,41-,42+,46-,47-,48+,49-,50-,51?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519064 (CHEMBL4586553) Show SMILES [H][C@@]12O[C@]1(COC(=O)C(C)(C)CC(O)=O)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:47:63.64:44,THB:68:49:63.64:44,51:49:63.64:44,62:63:49.47.50:44,41:43:51.63.62:47| Show InChI InChI=1S/C50H62O15/c1-27(2)46-23-32(25-59-41(54)30-18-12-9-13-19-30)49-36-39(46)63-50(64-46,65-49)33(51)22-16-8-7-11-17-28(3)35-29(4)38(61-42(55)31-20-14-10-15-21-31)48(58,37(35)49)43(56)47(40(36)62-47)26-60-44(57)45(5,6)24-34(52)53/h9-10,12-15,18-21,28-29,32-33,35-40,43,51,56,58H,1,7-8,11,16-17,22-26H2,2-6H3,(H,52,53)/t28-,29+,32+,33-,35+,36-,37-,38+,39-,40+,43-,46-,47+,48-,49-,50?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519061 (CHEMBL4533733) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)\C=C\c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:40:56.57:37,THB:61:42:56.57:37,34:36:44.56.55:40,44:42:56.57:37,55:56:42.40.43:37| Show InChI InChI=1S/C46H56O12/c1-26(2)42-23-31(24-53-40(50)30-18-12-8-13-19-30)45-35-38(42)56-46(57-42,58-45)32(48)20-14-6-5-9-15-27(3)34-28(4)37(54-33(49)22-21-29-16-10-7-11-17-29)44(52,36(34)45)41(51)43(25-47)39(35)55-43/h7-8,10-13,16-19,21-22,27-28,31-32,34-39,41,47-48,51-52H,1,5-6,9,14-15,20,23-25H2,2-4H3/b22-21+/t27-,28+,31+,32-,34+,35-,36-,37+,38-,39+,41-,42-,43+,44-,45-,46?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519089 (CHEMBL4560772) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](OC(C)=O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:41:57.58:38,THB:62:43:57.58:38,45:43:57.58:38,56:57:43.41.44:38,35:37:45.57.56:41| Show InChI InChI=1S/C46H56O13/c1-25(2)42-22-31(23-53-39(50)29-17-11-8-12-18-29)45-34-37(42)57-46(58-42,59-45)32(49)21-15-7-6-10-16-26(3)33-27(4)36(55-40(51)30-19-13-9-14-20-30)44(52,35(33)45)41(54-28(5)48)43(24-47)38(34)56-43/h8-9,11-14,17-20,26-27,31-38,41,47,49,52H,1,6-7,10,15-16,21-24H2,2-5H3/t26-,27+,31+,32-,33+,34-,35-,36+,37-,38+,41-,42-,43+,44-,45-,46?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519088 (CHEMBL4475196) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](OC(=O)c4ccc(cc4)[N+]([O-])=O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:49:65.66:46,THB:70:51:65.66:46,53:51:65.66:46,64:65:51.49.52:46,32:45:53.65.64:49| Show InChI InChI=1S/C51H57NO15/c1-28(2)47-25-34(26-61-43(54)31-16-10-7-11-17-31)50-38-41(47)65-51(66-47,67-50)36(62-44(55)33-21-23-35(24-22-33)52(59)60)20-14-6-5-9-15-29(3)37-30(4)40(63-45(56)32-18-12-8-13-19-32)49(58,39(37)50)46(57)48(27-53)42(38)64-48/h7-8,10-13,16-19,21-24,29-30,34,36-42,46,53,57-58H,1,5-6,9,14-15,20,25-27H2,2-4H3/t29-,30+,34+,36-,37+,38-,39-,40+,41-,42+,46-,47-,48+,49-,50-,51?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519086 (CHEMBL4460901) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](O)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](CO)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:30:38.39:27,THB:34:32:38.39:27,37:38:32.30.33:27,43:32:38.39:27,24:26:34.38.37:30| Show InChI InChI=1S/C30H46O10/c1-14(2)26-11-17(12-31)29-20-23(26)38-30(39-26,40-29)18(33)10-8-6-5-7-9-15(3)19-16(4)22(34)28(36,21(19)29)25(35)27(13-32)24(20)37-27/h15-25,31-36H,1,5-13H2,2-4H3/t15-,16+,17+,18-,19+,20-,21-,22+,23-,24+,25-,26-,27+,28-,29-,30?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519085 (CHEMBL4444766) Show SMILES [H][C@@]12O[C@]1(CO)C(=O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:38:54.55:35,THB:59:40:54.55:35,42:40:54.55:35,53:54:40.38.41:35,32:34:42.54.53:38| Show InChI InChI=1S/C44H52O12/c1-24(2)40-21-29(22-51-37(47)27-16-10-7-11-17-27)43-32-35(40)54-44(55-40,56-43)30(46)20-14-6-5-9-15-25(3)31-26(4)34(52-38(48)28-18-12-8-13-19-28)42(50,33(31)43)39(49)41(23-45)36(32)53-41/h7-8,10-13,16-19,25-26,29-36,45-46,50H,1,5-6,9,14-15,20-23H2,2-4H3/t25-,26+,29+,30-,31+,32-,33-,34+,35-,36+,40-,41+,42-,43-,44?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519082 (CHEMBL4527508) Show SMILES [H][C@@]12O[C@]1(COC(=O)c1ccccc1)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:46:62.63:43,THB:67:48:62.63:43,50:48:62.63:43,61:62:48.46.49:43,40:42:50.62.61:46| Show InChI InChI=1S/C51H58O13/c1-29(2)47-26-35(27-58-43(53)32-19-11-7-12-20-32)50-38-41(47)62-51(63-47,64-50)36(52)25-17-6-5-10-18-30(3)37-31(4)40(60-45(55)34-23-15-9-16-24-34)49(57,39(37)50)46(56)48(42(38)61-48)28-59-44(54)33-21-13-8-14-22-33/h7-9,11-16,19-24,30-31,35-42,46,52,56-57H,1,5-6,10,17-18,25-28H2,2-4H3/t30-,31+,35+,36-,37+,38-,39-,40+,41-,42+,46-,47-,48+,49-,50-,51?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519071 (CHEMBL4585270) Show SMILES [H][C@@]12O[C@]1(COC(=O)\C=C\c1ccc(OC)cc1)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:50:66.67:47,THB:71:52:66.67:47,54:52:66.67:47,65:66:52.50.53:47,44:46:54.66.65:50| Show InChI InChI=1S/C54H62O14/c1-31(2)50-28-37(29-62-47(57)35-17-11-8-12-18-35)53-42-45(50)66-54(67-50,68-53)39(55)21-15-7-6-10-16-32(3)41-33(4)44(64-48(58)36-19-13-9-14-20-36)52(60,43(41)53)49(59)51(46(42)65-51)30-63-40(56)27-24-34-22-25-38(61-5)26-23-34/h8-9,11-14,17-20,22-27,32-33,37,39,41-46,49,55,59-60H,1,6-7,10,15-16,21,28-30H2,2-5H3/b27-24+/t32-,33+,37+,39-,41+,42-,43-,44+,45-,46+,49-,50-,51+,52-,53-,54?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519072 (CHEMBL4580556) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](OC(=O)c4ccc5ccccc5c4)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:50:66.67:47,THB:71:52:66.67:47,54:52:66.67:47,65:66:52.50.53:47,32:46:54.66.65:50| Show InChI InChI=1S/C55H60O13/c1-31(2)51-28-39(29-62-47(57)35-19-10-7-11-20-35)54-42-45(51)66-55(67-51,68-54)40(63-49(59)38-26-25-34-18-15-16-23-37(34)27-38)24-14-6-5-9-17-32(3)41-33(4)44(64-48(58)36-21-12-8-13-22-36)53(61,43(41)54)50(60)52(30-56)46(42)65-52/h7-8,10-13,15-16,18-23,25-27,32-33,39-46,50,56,60-61H,1,5-6,9,14,17,24,28-30H2,2-4H3/t32-,33+,39+,40-,41+,42-,43-,44+,45-,46+,50-,51-,52+,53-,54-,55?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519073 (CHEMBL4536366) Show SMILES [H][C@@]12O[C@]1(COC(=O)C1(C)COC(C)(C)OC1)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:49:65.66:46,THB:70:51:65.66:46,53:51:65.66:46,64:65:51.49.52:46,43:45:53.65.64:49| Show InChI InChI=1S/C52H66O15/c1-29(2)48-24-34(25-59-42(54)32-19-13-10-14-20-32)51-37-40(48)65-52(66-48,67-51)35(53)23-17-9-8-12-18-30(3)36-31(4)39(63-43(55)33-21-15-11-16-22-33)50(58,38(36)51)44(56)49(41(37)64-49)28-60-45(57)47(7)26-61-46(5,6)62-27-47/h10-11,13-16,19-22,30-31,34-41,44,53,56,58H,1,8-9,12,17-18,23-28H2,2-7H3/t30-,31+,34+,35-,36+,37-,38-,39+,40-,41+,44-,48-,49+,50-,51-,52?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519074 (CHEMBL4442856) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](OC(=O)\C=C\c4ccccc4)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:48:64.65:45,THB:69:50:64.65:45,52:50:64.65:45,63:64:50.48.51:45,32:44:52.64.63:48| Show InChI InChI=1S/C53H60O13/c1-31(2)49-28-37(29-60-46(56)35-21-13-8-14-22-35)52-41-44(49)64-53(65-49,66-52)38(61-39(55)27-26-34-19-11-7-12-20-34)25-17-6-5-10-18-32(3)40-33(4)43(62-47(57)36-23-15-9-16-24-36)51(59,42(40)52)48(58)50(30-54)45(41)63-50/h7-9,11-16,19-24,26-27,32-33,37-38,40-45,48,54,58-59H,1,5-6,10,17-18,25,28-30H2,2-4H3/b27-26+/t32-,33+,37+,38-,40+,41-,42-,43+,44-,45+,48-,49-,50+,51-,52-,53?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519075 (CHEMBL4558004) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](O)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:30:46.47:27,THB:51:32:46.47:27,24:26:34.46.45:30,34:32:46.47:27,45:46:32.30.33:27| Show InChI InChI=1S/C37H50O11/c1-19(2)33-16-23(17-44-31(41)22-13-9-7-10-14-22)36-26-29(33)46-37(47-33,48-36)24(39)15-11-6-5-8-12-20(3)25-21(4)28(40)35(43,27(25)36)32(42)34(18-38)30(26)45-34/h7,9-10,13-14,20-21,23-30,32,38-40,42-43H,1,5-6,8,11-12,15-18H2,2-4H3/t20-,21+,23+,24-,25+,26-,27-,28+,29-,30+,32-,33-,34+,35-,36-,37?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519076 (CHEMBL4570883) Show SMILES [H][C@@]12O[C@]1(COC(=O)[C@@]13CC[C@@](C)(C(=O)O1)C3(C)C)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:14:13:16:10.9,1:51:67.68:48,THB:55:53:67.68:48,66:67:53.51.54:48,45:47:55.67.66:51,72:53:67.68:48| Show InChI InChI=1S/C54H66O15/c1-29(2)49-26-34(27-62-42(56)32-19-13-10-14-20-32)53-37-40(49)66-54(68-49,69-53)35(55)23-17-9-8-12-18-30(3)36-31(4)39(64-43(57)33-21-15-11-16-22-33)52(61,38(36)53)44(58)50(41(37)65-50)28-63-46(60)51-25-24-48(7,45(59)67-51)47(51,5)6/h10-11,13-16,19-22,30-31,34-41,44,55,58,61H,1,8-9,12,17-18,23-28H2,2-7H3/t30-,31+,34+,35-,36+,37-,38-,39+,40-,41+,44-,48+,49-,50+,51-,52-,53-,54?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519077 (CHEMBL4470135) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](OC(=O)c1ccccc1)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:46:62.63:43,THB:67:48:62.63:43,50:48:62.63:43,61:62:48.46.49:43,40:42:50.62.61:46| Show InChI InChI=1S/C51H58O13/c1-29(2)47-26-35(27-58-43(54)32-19-11-7-12-20-32)50-38-41(47)62-51(63-47,64-50)36(53)25-17-6-5-10-18-30(3)37-31(4)40(59-44(55)33-21-13-8-14-22-33)49(57,39(37)50)46(48(28-52)42(38)61-48)60-45(56)34-23-15-9-16-24-34/h7-9,11-16,19-24,30-31,35-42,46,52-53,57H,1,5-6,10,17-18,25-28H2,2-4H3/t30-,31+,35+,36-,37+,38-,39-,40+,41-,42+,46-,47-,48+,49-,50-,51?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519078 (CHEMBL4587134) Show SMILES [H][C@@]12O[C@]1(COC(=O)CC(C)(C)C(O)=O)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:47:63.64:44,THB:68:49:63.64:44,51:49:63.64:44,62:63:49.47.50:44,41:43:51.63.62:47| Show InChI InChI=1S/C50H62O15/c1-27(2)46-23-32(25-59-41(53)30-18-12-9-13-19-30)49-36-39(46)63-50(64-46,65-49)33(51)22-16-8-7-11-17-28(3)35-29(4)38(61-42(54)31-20-14-10-15-21-31)48(58,37(35)49)43(55)47(40(36)62-47)26-60-34(52)24-45(5,6)44(56)57/h9-10,12-15,18-21,28-29,32-33,35-40,43,51,55,58H,1,7-8,11,16-17,22-26H2,2-6H3,(H,56,57)/t28-,29+,32+,33-,35+,36-,37-,38+,39-,40+,43-,46-,47+,48-,49-,50?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519079 (CHEMBL4451784) Show SMILES [H][C@@]12O[C@]1(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](OC(=O)c4ccc(OC)cc4)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:48:64.65:45,THB:69:50:64.65:45,52:50:64.65:45,63:64:50.48.51:45,32:44:52.64.63:48| Show InChI InChI=1S/C52H60O14/c1-29(2)48-26-35(27-60-44(54)32-17-11-8-12-18-32)51-39-42(48)64-52(65-48,66-51)37(61-45(55)34-22-24-36(59-5)25-23-34)21-15-7-6-10-16-30(3)38-31(4)41(62-46(56)33-19-13-9-14-20-33)50(58,40(38)51)47(57)49(28-53)43(39)63-49/h8-9,11-14,17-20,22-25,30-31,35,37-43,47,53,57-58H,1,6-7,10,15-16,21,26-28H2,2-5H3/t30-,31+,35+,37-,38+,39-,40-,41+,42-,43+,47-,48-,49+,50-,51-,52?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519080 (CHEMBL4562111) Show SMILES [H][C@@]12O[C@]1(COC(=O)c1ccccc1)[C@@H](O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](OC(=O)c4ccccc4)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:54:70.71:51,THB:75:56:70.71:51,58:56:70.71:51,69:70:56.54.57:51,40:50:58.70.69:54| Show InChI InChI=1S/C58H62O14/c1-34(2)54-31-41(32-65-49(59)37-22-12-7-13-23-37)57-44-47(54)70-58(71-54,72-57)42(67-51(61)39-26-16-9-17-27-39)30-20-6-5-11-21-35(3)43-36(4)46(68-52(62)40-28-18-10-19-29-40)56(64,45(43)57)53(63)55(48(44)69-55)33-66-50(60)38-24-14-8-15-25-38/h7-10,12-19,22-29,35-36,41-48,53,63-64H,1,5-6,11,20-21,30-33H2,2-4H3/t35-,36+,41+,42-,43+,44-,45-,46+,47-,48+,53-,54-,55+,56-,57-,58?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50519081 (CHEMBL4537465) Show SMILES [H][C@@]12O[C@]1(COC(C)=O)[C@@H](OC(C)=O)[C@]1(O)[C@@H](OC(=O)c3ccccc3)[C@@H](C)[C@]3([H])[C@H](C)CCCCCC[C@@H](OC(C)=O)C45O[C@]6([H])[C@@]2([H])[C@](O4)([C@H](COC(=O)c2ccccc2)C[C@@]6(O5)C(C)=C)[C@@]13[H] |r,TLB:1:47:63.64:44,THB:68:49:63.64:44,51:49:63.64:44,62:63:49.47.50:44,38:43:51.63.62:47| Show InChI InChI=1S/C50H60O15/c1-27(2)46-24-35(25-57-43(54)33-19-13-10-14-20-33)49-38-41(46)63-50(64-46,65-49)36(59-31(6)52)23-17-9-8-12-18-28(3)37-29(4)40(61-44(55)34-21-15-11-16-22-34)48(56,39(37)49)45(60-32(7)53)47(42(38)62-47)26-58-30(5)51/h10-11,13-16,19-22,28-29,35-42,45,56H,1,8-9,12,17-18,23-26H2,2-7H3/t28-,29+,35+,36-,37+,38-,39-,40+,41-,42+,45-,46-,47+,48-,49-,50?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Agonist activity at Protein kinase C in human MT4 cells infected with HIV-1 NL4-3 assessed as inhibition of viral replication measured on day 3 post-...				J Med Chem 62: 6958-6971 (2019) Article DOI: 10.1021/acs.jmedchem.9b00339 BindingDB Entry DOI: 10.7270/Q2959MZJ
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50393228 (CHEMBL2153750) Show SMILES CN1CCN(CC1)c1nc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2cc(F)ccc2n1 |t:11| Show InChI InChI=1S/C25H21FN6O2/c1-31-8-10-32(11-9-31)25-28-19-7-6-14(26)12-16(19)22(29-25)21-20(23(33)30-24(21)34)17-13-27-18-5-3-2-4-15(17)18/h2-7,12-13,27H,8-11H2,1H3,(H,30,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PKCbeta-1 by scintillation proximity assay				J Med Chem 54: 6028-39 (2011) Article DOI: 10.1021/jm200469u BindingDB Entry DOI: 10.7270/Q2K35VR1
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Gachon University Curated by ChEMBL					Assay Description Inhibition of human PKCb2 using Histone H1 as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 163: 453-480 (2019) Article DOI: 10.1016/j.ejmech.2018.11.037 BindingDB Entry DOI: 10.7270/Q2TQ650N
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50235288 (CHEMBL4072879) Show SMILES CNCc1ccc2ccc(Cl)c(C3=C(C(=O)NC3=O)c3cn(C)c4ccccc34)c2c1 |t:12| Show InChI InChI=1S/C25H20ClN3O2/c1-27-12-14-7-8-15-9-10-19(26)21(17(15)11-14)23-22(24(30)28-25(23)31)18-13-29(2)20-6-4-3-5-16(18)20/h3-11,13,27H,12H2,1-2H3,(H,28,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PKCbeta1 (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assay				Bioorg Med Chem Lett 27: 781-786 (2017) Article DOI: 10.1016/j.bmcl.2017.01.038 BindingDB Entry DOI: 10.7270/Q2930WF1
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Gachon University Curated by ChEMBL					Assay Description Inhibition of human PKCb2 using Histone H1 as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 163: 453-480 (2019) Article DOI: 10.1016/j.ejmech.2018.11.037 BindingDB Entry DOI: 10.7270/Q2TQ650N
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50393219 (CHEMBL2151415) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2nc(nc3ccccc23)N2CCNCC2)c2ccccc12 |t:4| Show InChI InChI=1S/C25H22N6O2/c1-30-14-17(15-6-3-5-9-19(15)30)20-21(24(33)29-23(20)32)22-16-7-2-4-8-18(16)27-25(28-22)31-12-10-26-11-13-31/h2-9,14,26H,10-13H2,1H3,(H,29,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PKCbeta-1 by scintillation proximity assay				J Med Chem 54: 6028-39 (2011) Article DOI: 10.1021/jm200469u BindingDB Entry DOI: 10.7270/Q2K35VR1
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50486405 (CHEMBL2236794) Show SMILES NC[C@H]1Cc2c(C3=C(Nc4ccccc4)C(=O)NC3=O)c3ccccc3n2C1 |r,c:6| Show InChI InChI=1S/C22H20N4O2/c23-11-13-10-17-18(15-8-4-5-9-16(15)26(17)12-13)19-20(22(28)25-21(19)27)24-14-6-2-1-3-7-14/h1-9,13H,10-12,23H2,(H2,24,25,27,28)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PKCbeta2 (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-010-9439-6 BindingDB Entry DOI: 10.7270/Q2862KBF
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50486405 (CHEMBL2236794) Show SMILES NC[C@H]1Cc2c(C3=C(Nc4ccccc4)C(=O)NC3=O)c3ccccc3n2C1 |r,c:6| Show InChI InChI=1S/C22H20N4O2/c23-11-13-10-17-18(15-8-4-5-9-16(15)26(17)12-13)19-20(22(28)25-21(19)27)24-14-6-2-1-3-7-14/h1-9,13H,10-12,23H2,(H2,24,25,27,28)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PKCbeta2 (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-010-9439-6 BindingDB Entry DOI: 10.7270/Q2862KBF
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM2683 (2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C25H24N4O2/c1-28(2)12-7-13-29-15-19(17-9-4-6-11-21(17)29)23-22(24(30)27-25(23)31)18-14-26-20-10-5-3-8-16(18)20/h3-6,8-11,14-15,26H,7,12-13H2,1-2H3,(H,27,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.4	23
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM33970 (maleimide derivative, 12) Show SMILES CN1CCN(CC1)c1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc2c1 |t:11| Show InChI InChI=1S/C27H24N4O2/c1-30-10-12-31(13-11-30)18-14-17-6-2-3-7-19(17)21(15-18)24-25(27(33)29-26(24)32)22-16-28-23-9-5-4-8-20(22)23/h2-9,14-16,28H,10-13H2,1H3,(H,29,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.4	23
Novartis					Assay Description Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...				J Med Chem 52: 6193-6 (2009) Article DOI: 10.1021/jm901108b BindingDB Entry DOI: 10.7270/Q25X278Q
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM33970 (maleimide derivative, 12) Show SMILES CN1CCN(CC1)c1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc2c1 |t:11| Show InChI InChI=1S/C27H24N4O2/c1-30-10-12-31(13-11-30)18-14-17-6-2-3-7-19(17)21(15-18)24-25(27(33)29-26(24)32)22-16-28-23-9-5-4-8-20(22)23/h2-9,14-16,28H,10-13H2,1H3,(H,29,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PKCbeta-1 by scintillation proximity assay				J Med Chem 54: 6028-39 (2011) Article DOI: 10.1021/jm200469u BindingDB Entry DOI: 10.7270/Q2K35VR1
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50235287 (CHEMBL4089217) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c(Cl)ccc3ccc(CN4CCC4)cc23)c2ccccc12 |t:4| Show InChI InChI=1S/C27H22ClN3O2/c1-30-15-20(18-5-2-3-6-22(18)30)24-25(27(33)29-26(24)32)23-19-13-16(14-31-11-4-12-31)7-8-17(19)9-10-21(23)28/h2-3,5-10,13,15H,4,11-12,14H2,1H3,(H,29,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PKCbeta1 (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assay				Bioorg Med Chem Lett 27: 781-786 (2017) Article DOI: 10.1016/j.bmcl.2017.01.038 BindingDB Entry DOI: 10.7270/Q2930WF1
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM33971 (AEB071 | Sotrastaurin | med.21724, Compound 190) Show SMILES CN1CCN(CC1)c1nc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc2n1 |t:11| Show InChI InChI=1S/C25H22N6O2/c1-30-10-12-31(13-11-30)25-27-19-9-5-3-7-16(19)22(28-25)21-20(23(32)29-24(21)33)17-14-26-18-8-4-2-6-15(17)18/h2-9,14,26H,10-13H2,1H3,(H,29,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PKCbeta1 (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assay				Bioorg Med Chem Lett 27: 781-786 (2017) Article DOI: 10.1016/j.bmcl.2017.01.038 BindingDB Entry DOI: 10.7270/Q2930WF1
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50486401 (CHEMBL2236799) Show SMILES CN(C)C[C@H]1CCn2c(C1)c(C1=C(Nc3ccccc3)C(=O)NC1=O)c1ccccc21 |r,c:12| Show InChI InChI=1S/C25H26N4O2/c1-28(2)15-16-12-13-29-19-11-7-6-10-18(19)21(20(29)14-16)22-23(25(31)27-24(22)30)26-17-8-4-3-5-9-17/h3-11,16H,12-15H2,1-2H3,(H2,26,27,30,31)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PKCbeta2 (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-010-9439-6 BindingDB Entry DOI: 10.7270/Q2862KBF
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50393226 (CHEMBL2153748) Show SMILES CN1CCN(CC1)c1cc2ccccc2c(n1)C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12 |t:20| Show InChI InChI=1S/C26H23N5O2/c1-30-10-12-31(13-11-30)21-14-16-6-2-3-7-17(16)24(28-21)23-22(25(32)29-26(23)33)19-15-27-20-9-5-4-8-18(19)20/h2-9,14-15,27H,10-13H2,1H3,(H,29,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PKCbeta-1 by scintillation proximity assay				J Med Chem 54: 6028-39 (2011) Article DOI: 10.1021/jm200469u BindingDB Entry DOI: 10.7270/Q2K35VR1
					More data for this Ligand-Target Pair

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