Compile Data Set for Download or QSAR

Found 7 hits of ic50 for UniProtKB: G1SVH0   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosylhomocysteinase (Oryctolagus cuniculus (Rabbit))	BDBM369458 (US10227373, Compound D-Isoneplanocin) Show SMILES Nc1ncnc2n(cnc12)C1=C[C@H](CO)[C@@H](O)[C@H]1O |r,t:12| Show InChI InChI=1S/C11H13N5O3/c12-10-7-11(14-3-13-10)16(4-15-7)6-1-5(2-17)8(18)9(6)19/h1,3-5,8-9,17-19H,2H2,(H2,12,13,14)/t5-,8-,9+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...				J Med Chem 51: 1904-12 (2008) BindingDB Entry DOI: 10.7270/Q24Q7X8H
					More data for this Ligand-Target Pair
Adenosylhomocysteinase (Oryctolagus cuniculus (Rabbit))	BDBM50140074 (CHEMBL2059155 | US10227373, Compound 3-Bromo-3-dea...) Show SMILES Nc1ncc(Br)c2n(cnc12)[C@@H]1C=C(CO)[C@@H](O)[C@H]1O |r,t:14| Show InChI InChI=1S/C12H13BrN4O3/c13-6-2-15-12(14)8-9(6)17(4-16-8)7-1-5(3-18)10(19)11(7)20/h1-2,4,7,10-11,18-20H,3H2,(H2,14,15)/t7-,10-,11+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...				J Med Chem 51: 1904-12 (2008) BindingDB Entry DOI: 10.7270/Q24Q7X8H
					More data for this Ligand-Target Pair
Adenosylhomocysteinase (Oryctolagus cuniculus (Rabbit))	BDBM50096906 (CHEMBL154745 | US10227373, Compound D-3-Deazaisone...) Show SMILES Nc1nccc2n(cnc12)[C@@H]1C=C(CO)[C@@H](O)[C@H]1O |t:13| Show InChI InChI=1S/C12H14N4O3/c13-12-9-7(1-2-14-12)16(5-15-9)8-3-6(4-17)10(18)11(8)19/h1-3,5,8,10-11,17-19H,4H2,(H2,13,14)/t8-,10-,11+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.19	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...				J Med Chem 51: 1904-12 (2008) BindingDB Entry DOI: 10.7270/Q24Q7X8H
					More data for this Ligand-Target Pair
Adenosylhomocysteinase (Oryctolagus cuniculus (Rabbit))	BDBM50465905 (CHEMBL4285617) Show SMILES Nc1cccc2n(cnc12)[C@H]1[C@H](O)[C@H](O)C(CO)=C1F |r,c:19| Show InChI InChI=1S/C13H14FN3O3/c14-9-6(4-18)12(19)13(20)11(9)17-5-16-10-7(15)2-1-3-8(10)17/h1-3,5,11-13,18-20H,4,15H2/t11-,12-,13+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibition of SAHase from rabbit erythrocytes using S-adenosyl-L-homocysteine as substrate preincubated for 5 mins followed by substrate addition and...				Bioorg Med Chem Lett 28: 3674-3675 (2018) Article DOI: 10.1016/j.bmcl.2018.10.030 BindingDB Entry DOI: 10.7270/Q2CN76KB
					More data for this Ligand-Target Pair
Adenosylhomocysteinase (Oryctolagus cuniculus (Rabbit))	BDBM369457 (US10227373, Compound 3-Deazaneplanocin) Show SMILES Nc1nccc2n(cnc12)C1C=C(CO)[C@@H](O)[C@H]1O |r,t:13| Show InChI InChI=1S/C12H14N4O3/c13-12-9-7(1-2-14-12)16(5-15-9)8-3-6(4-17)10(18)11(8)19/h1-3,5,8,10-11,17-19H,4H2,(H2,13,14)/t8?,10-,11+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...				J Med Chem 51: 1904-12 (2008) BindingDB Entry DOI: 10.7270/Q24Q7X8H
					More data for this Ligand-Target Pair
Adenosylhomocysteinase (Oryctolagus cuniculus (Rabbit))	BDBM369459 (US10227373, Compound L-Isoneplanocin) Show SMILES Nc1ncnc2n(cnc12)C1=C[C@@H](CO)[C@@H](O)[C@H]1O |r,t:12| Show InChI InChI=1S/C11H13N5O3/c12-10-7-11(14-3-13-10)16(4-15-7)6-1-5(2-17)8(18)9(6)19/h1,3-5,8-9,17-19H,2H2,(H2,12,13,14)/t5-,8+,9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...				J Med Chem 51: 1904-12 (2008) BindingDB Entry DOI: 10.7270/Q24Q7X8H
					More data for this Ligand-Target Pair
Adenosylhomocysteinase (Oryctolagus cuniculus (Rabbit))	BDBM369461 (US10227373, Compound L-3-Deazaisoneplanocin) Show SMILES Nc1nccc2n(cnc12)[C@H]1C=C(CO)[C@@H](O)[C@H]1O |r,t:13| Show InChI InChI=1S/C12H14N4O3/c13-12-9-7(1-2-14-12)16(5-15-9)8-3-6(4-17)10(18)11(8)19/h1-3,5,8,10-11,17-19H,4H2,(H2,13,14)/t8-,10+,11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...				J Med Chem 51: 1904-12 (2008) BindingDB Entry DOI: 10.7270/Q24Q7X8H
					More data for this Ligand-Target Pair