Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: G1TCS6   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G_PROTEIN_RECEP_F1_2 domain-containing protein (Oryctolagus cuniculus (Rabbit))	BDBM405272 (1-(4-(7-(2,6-difluorobenzyl)-3-((dimethylamino)met...) Show SMILES CNC(=O)Nc1ccc(cc1)-n1nc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccc(OC)nn3)c(=O)c2c1CN(C)C Show InChI InChI=1S/C28H27F2N9O4/c1-31-27(41)32-16-8-10-17(11-9-16)39-21(15-36(2)3)24-25(35-39)37(14-18-19(29)6-5-7-20(18)30)28(42)38(26(24)40)22-12-13-23(43-4)34-33-22/h5-13H,14-15H2,1-4H3,(H2,31,32,41)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceutical Co., Ltd US Patent					Assay Description Rabbit: This assay was used to determine the inhibition effect of the present compounds on the activity of rabbit GnRHr protein expressed by rabbit G...				US Patent US10344034 (2019) BindingDB Entry DOI: 10.7270/Q29Z978Z
					More data for this Ligand-Target Pair
G_PROTEIN_RECEP_F1_2 domain-containing protein (Oryctolagus cuniculus (Rabbit))	BDBM405271 (1-(4-(3-((dimethylamino)methyl)-5-(2-fluoro-3-meth...) Show SMILES CNC(=O)Nc1ccc(cc1)-n1nc2n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(-c3cccc(OC)c3F)c(=O)c2c1CN(C)C |(-9.14,-1.9,;-8.37,-.56,;-6.83,-.56,;-6.06,-1.9,;-6.06,.77,;-4.52,.77,;-3.75,-.56,;-2.21,-.56,;-1.44,.77,;-2.21,2.1,;-3.75,2.1,;.1,.77,;1.01,-.48,;2.47,,;3.8,-.77,;3.8,-2.31,;5.14,-3.08,;6.47,-2.31,;7.81,-1.54,;7.81,-3.08,;7.81,-4.62,;6.47,-5.39,;5.14,-4.62,;3.8,-5.39,;2.47,-4.62,;3.8,-6.93,;5.14,-6.16,;5.14,,;6.47,-.77,;5.14,1.54,;6.47,2.31,;7.81,1.54,;9.14,2.31,;9.14,3.85,;7.81,4.62,;7.81,6.16,;6.47,6.93,;6.47,3.85,;5.14,4.62,;3.8,2.31,;3.8,3.85,;2.47,1.54,;1.01,2.02,;.61,3.5,;-.88,3.9,;-1.28,5.39,;-1.97,2.81,)| Show InChI InChI=1S/C31H28F5N7O4/c1-37-29(45)38-17-11-13-18(14-12-17)43-23(16-40(2)3)25-27(39-43)41(15-19-20(31(34,35)36)7-5-8-21(19)32)30(46)42(28(25)44)22-9-6-10-24(47-4)26(22)33/h5-14H,15-16H2,1-4H3,(H2,37,38,45)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceutical Co., Ltd US Patent					Assay Description Rabbit: This assay was used to determine the inhibition effect of the present compounds on the activity of rabbit GnRHr protein expressed by rabbit G...				US Patent US10344034 (2019) BindingDB Entry DOI: 10.7270/Q29Z978Z
					More data for this Ligand-Target Pair
G_PROTEIN_RECEP_F1_2 domain-containing protein (Oryctolagus cuniculus (Rabbit))	BDBM405274 (1-(4-(7-(2,6-difluorobenzyl)-3-((dimethylamino)met...) Show SMILES CONC(=O)Nc1ccc(cc1)-n1nc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccc(OC)nn3)c(=O)c2c1CN(C)C Show InChI InChI=1S/C28H27F2N9O5/c1-36(2)15-21-24-25(34-39(21)17-10-8-16(9-11-17)31-27(41)35-44-4)37(14-18-19(29)6-5-7-20(18)30)28(42)38(26(24)40)22-12-13-23(43-3)33-32-22/h5-13H,14-15H2,1-4H3,(H2,31,35,41)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceutical Co., Ltd US Patent					Assay Description Rabbit: This assay was used to determine the inhibition effect of the present compounds on the activity of rabbit GnRHr protein expressed by rabbit G...				US Patent US10344034 (2019) BindingDB Entry DOI: 10.7270/Q29Z978Z
					More data for this Ligand-Target Pair