Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412768 (N-(3-fluoropyridin-4-yl)-5-methyl-2-(6-methylpyrid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412735 (2-(6-(difluoromethyl)pyridin-2-yl)-N-(3-fluoropyri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412743 (N-(3-fluoropyridin-4-yl)-2-(pyridin-2-yl)-7H-pyrro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412766 (N-(4-((2-(6-(difluoromethyl)pyridin-2-yl)-7H-pyrro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412738 (2-(pyrrolidin-1-yl)-N-(4-((2-(6-(trifluoromethyl)p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.420 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412739 (2-(4-methylpiperazin-1-yl)-N-(4-((2-(6-(trifluorom...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412745 (N-(3-fluoropyridin-4-yl)-2-(6-(trifluoromethyl)pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PDB UniChem | PDB US Patent | n/a | n/a | 0.560 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412773 (N-methyl-N-{2-[6-(trifluoromethyl)pyridin-2-yl]-7H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412775 (3-chloro-N-{2-[6-(trifluoromethyl)pyridin-2-yl]-7H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412746 (2-(5-fluoro-6-methylpyridin-2-yl)-N-(3-fluoropyrid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412747 (2-(6-(difluoromethyl)pyridin-2-yl)-4-(1H-pyrrolo[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412774 (3-(trifluoromethyl)-N-{2-[6-(trifluoromethyl)pyrid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412755 (N-(4-((2-(6-(trifluoromethyl)pyridin-2-yl)-7H-pyrr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412734 (N-(3-fluoropyridin-4-yl)-2-(6-methylpyridin-2-yl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412751 (N-(4-((2-(6-(difluoromethyl)pyridin-2-yl)-7H-pyrro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412759 (N-(4-((2-(6-(trifluoromethyl)pyridin-2-yl)-7H-pyrr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412778 (N-[4-({2-[6-(difluoromethyl)pyridin-2-yl]-5-{[(2-h...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412741 (2-(6-(difluoromethyl)pyridin-2-yl)-N-(3-fluoropyri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412752 (US10399987, Example 17 | methyl (4-((2-(6-(difluor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412764 (N-(4-((2-(5-fluoro-6-methylpyridin-2-yl)-7H-pyrrol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412767 (2-morpholino-N-(4-((2-(6-(trifluoromethyl)pyridin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412736 (N-(4-((2-(6-(difluoromethyl)pyridin-2-yl)-7H-pyrro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412781 (N-[2-(5-fluoro-6-methylpyridin-2-yl)-7H-pyrrolo[2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.790 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412762 (3-methyl-N-(4-((2-(6-(trifluoromethyl)pyridin-2-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.850 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412772 (3-methyl-N-{2-[6-(trifluoromethyl)pyridin-2-yl]-7H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.870 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412776 (N-[4-({2-[6-(trifluoromethyl)pyridin-2-yl]-7H-pyrr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.870 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412756 (N-(4-((2-(pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412749 (2-(5-fluoropyridin-2-yl)-N-(3-fluoropyridin-4-yl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 0.910 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412757 (N-(4-((2-(6-methylpyridin-2-yl)-7H-pyrrolo[2,3-d]p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412780 (N-[2-(5-fluoro-6-methylpyridin-2-yl)-7H-pyrrolo[2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412744 (2-(pyridin-2-yl)-4-(1H-pyrrolo[3,2-c]pyridin-1-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412753 (N-(5-fluoro-4-((2-(5-fluoro-6-methylpyridin-2-yl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412770 (1-(((2-(6-(difluoromethyl)pyridin-2-yl)-4-((3-fluo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412782 (N-(4-{[2-(5-fluoro-6-methylpyridin-2-yl)-7H-pyrrol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412760 (N-(4-((2-(6-(difluoromethyl)pyridin-2-yl)-5-methyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412777 (3-methoxy-N-{2-[6-(trifluoromethyl)pyridin-2-yl]-7...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412771 (N-[3-fluoro-4-({2-[6-(trifluoromethyl)pyridin-2-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412784 (N-(6-{4-[(3-chloropyridin-4-yl)amino]-7H-pyrrolo[2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412765 (US10399987, Example 30 | methyl (4-((2-(6-(trifluo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412779 (N-[4-({2-[6-(difluoromethyl)pyridin-2-yl]-5-{[(2-h...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412761 (3,3-dimethyl-N-(4-((2-(6-(trifluoromethyl)pyridin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412742 (2-(6-(difluoromethyl)pyridin-2-yl)-N-(3-fluoropyri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412748 (N-(2-chloro-5-fluoropyridin-4-yl)-2-(5-fluoro-6-me...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412783 (N-(6-{4-[methyl(pyridin-4-yl)amino]-7H-pyrrolo[2,3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412769 (N-(3-fluoropyridin-4-yl)-5-methyl-2-(6-(trifluorom...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412758 (N-(4-((2-(5-(trifluoromethyl)pyridin-2-yl)-7H-pyrr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM412754 (1-(4-((2-(6-(difluoromethyl)pyridin-2-yl)-7H-pyrro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myer Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10399987 (2019) BindingDB Entry DOI: 10.7270/Q2222X4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM21506 (Dihydropyrrolopyrazole, 15a | dimethyl[2-({4-[2-(p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | 29 | n/a | n/a | 7.5 | 30 |
Lilly Research Laboratories | Assay Description The kinase activity was assayed by the autophosphorylation reaction of ALK5 (T204D) in the presence of 4 uM ATP and [33P]-gamma-ATP. After incubation... | J Med Chem 51: 2302-2306 (2008) Article DOI: 10.1021/jm701199p BindingDB Entry DOI: 10.7270/Q2G15Z4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM21505 (7-(2-chloroethoxy)-4-[2-(pyridin-2-yl)-4H,5H,6H-py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 33 | n/a | 66 | n/a | n/a | 7.5 | 30 |
Lilly Research Laboratories | Assay Description The kinase activity was assayed by the autophosphorylation reaction of ALK5 (T204D) in the presence of 4 uM ATP and [33P]-gamma-ATP. After incubation... | J Med Chem 51: 2302-2306 (2008) Article DOI: 10.1021/jm701199p BindingDB Entry DOI: 10.7270/Q2G15Z4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 [4-503,T204D] (Homo sapiens (Human)) | BDBM21510 (Dihydropyrrolopyrazole, 16a | dimethyl[5-({4-[2-(p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 47 | n/a | 24 | n/a | n/a | 7.5 | 30 |
Lilly Research Laboratories | Assay Description The kinase activity was assayed by the autophosphorylation reaction of ALK5 (T204D) in the presence of 4 uM ATP and [33P]-gamma-ATP. After incubation... | J Med Chem 51: 2302-2306 (2008) Article DOI: 10.1021/jm701199p BindingDB Entry DOI: 10.7270/Q2G15Z4K | |||||||||||
More data for this Ligand-Target Pair |
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